[daveman]

http://myhealth.hollandhospital.org/HealthTopics/allergies/dec07acMain.htm

Dr. Ronald Simon, an allergist at Scripps Clinic in San Diego , told HealthDay that he and his colleagues have treated patients with a mixture of contraceptive gel and an anti-allergy medication, cromolyn.

Thanks Horizon, I'll be contacting Dr. Ronald. 

This would be for women, (perhaps the contraceptive gel component would have to be reconsidered []).

It mentions the potential for a prostatic protein (part of the semen one would imagine) being a guilty culprit as well as sperm.

So interesting. They too are doing desensitizations.

[Guthrie]

He wasn't keen at all.  He said anyone can be hypersensative to their own semen/sperm as it's a foreign substance with 23 chromosomes and that's why it's produced and stored in a blood barrier (testies) away from the body.

The one-day desensitization is the goal for all of us.

Fascinating news!

The implication is that POIS may still be a reaction to semen/sperm that has broken the blood barrier, but that the skinprick is not at all relevant in the diagnosis? And that's why the potential for desensitization still exists?

No, I'm just not sure if I'm following the implications.

He says he doesn't agree that the skinprick test has any value, for the reasons he mentions, but he agrees that there can be a semen allergy once the blood barrier is broken, and therefore desensitization is possible.

Just trying to clarify that.

My sense of it (based on Limejuice's reporting from Dr. Bernstein) is:

Sperm can cause an allergic reaction in people in general.  So the skinprick test with sperm wouldn't indicate anything one way or another about POIS.  Both POIS and non-POIS people would be likely to react.

However, if there is a 'gap' or some other problem internally, and the sperm reaches the bloodstream, then this could *also* cause an allergic reaction.  So, in this case, it could be possible to treat it with desensitization.

His bottom line seems to be: the allergen hypothesis may not be useful for testing for POIS, but it may still be useful for treating POIS.

[Vincent M]

And on that note, did you manage to cut down your frequency of masturbation?

P.S. you sound like a very smart, decent guy and I hope your life currently is on the way up .

I think my masturbation frequency has somewhat decreased due to natural aging(maybe?) as I'm doing it closer to 3-4 times a day and rarely maybe once a week I'll do it more than that. I find that on days when I'm depressed I do it the most. It seems as if the fenugreek and garlic I've been taking have somewhat helped me control that addiction since they seem to be reducing my anxiety and depression slightly, which may have been part of the causes of my masturbation addiction.

You sound like a good, intelligent person as well and I'm glad you introduced yourself. The more active members we have here the better our publicity gets and the easier it is for new members to find us. Plus everyone has some helpful information to share.

[lidridop]

Hey Willem, thanks for the welcome!

  I'm normally a totally happy, upbeat guy, but POIS makes me feel like a dull jerk.

Tell me about it - in February i was having the best fun day off with my girlfriend, in such a good mood, just hanging out! Watching a game on tv, half time break comes and we did it. BAM! POIS ruins my day!! 100%!! For the rest of the day I was an irritable freak and had to take a nap! wtf. It's a head wrecker!!

Out of interest, does anyone have any of the following symptoms when masturbating regularly:

Dark Circles,
Paleness,
Tired, fatigued appearance?

I do believe that POIS and ejaculation is  a factor for these symptoms as well as normal POIS symptoms - especially if frequency of ejaculation is high. I don't want to know this stuff but when you're affected by it, it tends to become an interest of yours. Right now I'm just turned off by the whole thing - I don't want to have an orgasm, the price to pay is very high for a 10 second great feeling.

I'm beginning to think this is natures way of saying "hey, this is enough, you just need this to reproduce, dont abuse it!!".
Much like drugs, alcohol, bad food etc - it's nice at the time but too much/abuse it and it's baaaad news!!!

I'm trying to live my life without it right now and think about other things, which is fine - but when I live with my girlfriend again (we're long distance at mo), I don't want to f**k things up with this condition!! It's a total head wreck as all of us know only too well. Ready and willing to find a cure. Cue much research from me, I wont rest until this thing is gone!! 

[lidridop]

I think my masturbation frequency has somewhat decreased due to natural aging(maybe?) as I'm doing it closer to 3-4 times a day and rarely maybe once a week I'll do it more than that. I find that on days when I'm depressed I do it the most.

Really? How can you do it that often? I would probably collapse into a coma dude!! Why don't you give yourself a chance to recover? Sorry if i'm intruding, but your case sounds like one of the worst though in terms of your symptoms, and 3-4 times a day wouldn't be helping you.. have you tried eating well, exercising and cutting it down to maybe 3-4 times weekly instead of daily? Or is that too hard? Sorry again, I just feel for you, I was in that situation and realllly had to cut back or else things were not going anywhere. If I did that these days, I would collapse, no doubts.

[Willem]

http://myhealth.hollandhospital.org/HealthTopics/allergies/dec07acMain.htm

Dr. Ronald Simon, an allergist at Scripps Clinic in San Diego , told HealthDay that he and his colleagues have treated patients with a mixture of contraceptive gel and an anti-allergy medication, cromolyn.

Thanks Horizon, I'll be contacting Dr. Ronald. 

This would be for women, (perhaps the contraceptive gel component would have to be reconsidered []).

It mentions the potential for a prostatic protein (part of the semen one would imagine) being a guilty culprit as well as sperm.

So interesting. They too are doing desensitizations.

Exactly.  An interest and familiarity with the ailment and a willingness to do desensitization are the key.  My previous allergist was totally cool, but didn't specialize in handling semen. 

[sameer7777]

Thankyou everyone , 1st i thought i am alone ......we have to fight and stay together and share info with each other .......so from now on you guys are my family .....May God help us .......keep in touch guys

[Vincent M]

Really? How can you do it that often? I would probably collapse into a coma dude!! Why don't you give yourself a chance to recover? Sorry if i'm intruding, but your case sounds like one of the worst though in terms of your symptoms, and 3-4 times a day wouldn't be helping you.. have you tried eating well, exercising and cutting it down to maybe 3-4 times weekly instead of daily? Or is that too hard? Sorry again, I just feel for you, I was in that situation and realllly had to cut back or else things were not going anywhere. If I did that these days, I would collapse, no doubts.

I have tried using diet and exercise to reduce my sex drive, but that failed. Even tried prozac to calm my sex drive, but that just made some of my hair fall out. So yeahh...what can I say masturbation is truly an addiction for me just like alcohol is for an alcoholic except worse, because it's like an alcoholic with a never ending supply of vodka right by his bedside. Even if you know it's destroying your body & mind it's impossible to stop a true addiction with mere willpower. And trust me I know it's killing me. That's why I'm going the route of herbal supplements since they don't require much willpower and they won't cause hair loss like prozac did.

On that note I just ordered some relora. I've read that it reduces anxiety and helps you sleep better and the scientific studies on it seem legit. There's also the previous successes on this forum with relora so looks like it's worth a try.

Dan, I know you're trying to help give me some pointers so thanks man. I appreciate any advice. *EDIT*- I would be interested in any advice to reduce my sex drive though.

[Vincent M]

Thankyou everyone , 1st i thought i am alone ......we have to fight and stay together and share info with each other .......so from now on you guys are my family .....May God help us .......keep in touch guys

Well Sameer, you're not alone anymore that's for sure.

[lidridop]

Vincent, I don't necessarily believe that sex drive should ALWAYS mean - "I really need to masturbate or have sex." You can use that energy and desire - your sex drive, for "lust of life" pursuits instead. I'm not saying 100% abstinence, that's not wise either.

  I do have tips to reduce your need for masturbation. Do you mind if I private message you? I have a definite plan, you are NOT over the edge yet and a LOT can be done, trust me. 

[demografx]

You'd think everyone [here] would be arguing like a bunch of cantankerous geezers.

Oh, you've missed some real doozies here, trust me!  []

[demografx]

I think my masturbation frequency has somewhat decreased due to natural aging(maybe?) as I'm doing it closer to 3-4 times a day and rarely maybe once a week I'll do it more than that.

Really? How can you do it that often? I would probably collapse into a coma dude!!

At that frequency you'd find many of us in the ER or the morgue!

[demografx]

dan-ireland, welcome to the POIS thread of The Naked Science Forum!




Here are some POIS resources which may be helpful to you:

The Learning Channel (TLC) upcoming feature TV presentation on POIS, featuring our member here at this forum, "Animus". They're planning to air it on May 22, 10pm Eastern Standard time. Animus will keep us informed of any changes.

Our POIS Information Website, built by "mat780", is here:
http://sites.google.com/site/POISwebsite/

The POIS Information Website is home to the famous POIS Forum Compendium, written by "Pyropeach", and contains theories already discussed here and treatments that have both worked and failed.

Please see "B_Jim"'s POIS Summary of All Cases, here as well as others on the Web. This includes remedies that we have tested, and results.
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg149009#msg149009

"Girlwind" has created an excellent POIS Video:

Our new POIS chatroom (realtime chat). Invite or visit another member(s) there, ANY TIME. We can all get to know each other better:
http://forums.delphiforums.com/POIS/chat


* Most recent POIS Research Studies, 2011 *

If you will send Prof. dr. Waldinger an e-mail, stating that you have read his message on the Forum, at http://www.thenakedscientists.com/forum/index.php?topic=6576.msg340138#msg340138 and that you are willing to fill in a questionnaire, he will send you the copies of both 2011 research articles by return through email. At a later date, he will send you the questionnaire which, after having filled in, you should send him back by e-mail.
His email:
prof.dr.waldinger.pois@gmail.com

Prof. dr. Marcel D. Waldinger's website:
http://www.post-orgasmic-illness-syndrome.com/en/index.html


First POIS Research Study, 2002

We have a copy of the first formal medical investigation on POIS by Prof. dr. Marcel D. Waldinger,MD,PhD, and Dr. Dave Schweitzer, MD.

  
Recent POIS Research Study, 2010

CASE REPORT
Postorgasm Illness Syndrome - A Spectrum of Illnesses
Jane Ashby, MRCP, and David Goldmeier, MRCP
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg316781#msg316781


British Medical Journal Case Report, 2010

Case study by Dr. Selwyn Dexter of a patient with a headache-featured POIS symptom treated with progesterone/norethisterone.
http://casereports.bmj.com/content/2010/bcr.10.2009.2359.short?rss=1


There are a couple of ways to get any or all of the above 3 studies: (1) if you want a PDF copy, send me a Private Message (PM) with your regular email address (use "AT" instead of "@" ) and I'll send you back the PDF.

Or, if you prefer, (2) I can simply reply with a Private Message (no regular email needed) and provide you with a simple text version embedded in your PM.

To send a Private Message, click on "Messages" at the top of this page. At the Messages page, click on "New Message". From that point on, it works just like posting a message here, except that it only goes to the person(s) you designate.

Remember to put a quote around my name, i.e., "demografx".


New York Times article,

January 20, 2009
Mind
Sex and Depression: In the Brain, if Not the Mind
By RICHARD A. FRIEDMAN, M.D.
http://www.nytimes.com/2009/01/20/health/views/20mind.html?_r=1&scp=1&sq=friedman%20sexual%20January%2020&st=cse

- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

In addition to serving our own informational interests, the resources listed above can be useful for you to show our credibility to the medical world - which often shows little understanding and is sometimes skeptical of our condition: POIS has scientific underpinnings and POIS is not "just another psychological problem" related to sex - to be treated by the psychiatric/psychotherapeutic community. All of this information can greatly help you to fight the immediate reaction of some doctors: so just tell them, "IT'S NOT 'ALL IN OUR HEADS'! "

Also, it can be helpful when dealing with medical professionals to point out the successful existence of our rapidly growing forum, which has already been referenced in respectable sources such as the Journal of Sexual Medicine (Dr. Waldinger's study), British Medical Journal and wikipedia:
http://en.wikipedia.org/wiki/Postorgasmic_illness_syndrome

For over 4 years, our POIS forum has attracted over 200 POIS sufferers worldwide who have posted here, research on an additional 200 sufferers elsewhere on the internet, plus over 1,000,000 page visits. Not bad for a rare malady!

[demografx]

dan-ireland, this post will help you find information about POIS that we have already discussed, by tailoring a Google search to this forum:


SEARCH THE FORUM WITH GOOGLE

We have an overwhelming amount of data: more than 4 years' worth of posts (over  10,000 posts!) from 200+ Forum members, and an additional 200 POIS sufferers found elsewhere on the Internet by Member B_Jim.

In the Google search box, type
whatever-it-is-you're-interested-in-finding-out[space]POIS[space]site:http://thenakedscientists.com/

for example, I tried
nocturnal emission POIS site:http://thenakedscientists.com/

and 740 results came up for "nocturnal emission" within the Forum.

be careful with spaces (you can use them before the word "site") and no-spaces (everything after the word "site")

Google even provides you results with the Message# for each result. But Message #'s do change, so be patient and look for the approximate Message#.

[lidridop]

dan-ireland, this post will help you find information about POIS that we have already discussed, by tailoring a Google search to this forum:

Thanks very much Demo, and thanks for the welcome, hope I can make a difference

[Animus]

I recently spoke with the TV producer, and she said she'll definitely send me a DVD of the show upon airing. She added that they usually don't post the shows online, however I have been able to view other episodes of that series on YouTube, or online somehow.  So I don't know if that will be available.

The name of the series is called "Strange Sex" on TLC. And they do have a few episodes online. To be honest, it's not the type of show I'd watch voluntarily. Kind of gross, fetishistic at times! But...

That said, once I receive the DVD, I will do everything I can to make it available by sending copies of it, or posting it somehow online myself, maybe with someone's help.

It is still on schedule to air on May 22nd on TLC at 10pm. Don't forget the popcorn!

I wonder if you or another one of us posted the episode on youtube if it would go against some kind of copyright rule. Perhaps that would be a good question to ask the producer? Maybe they would even give you a digital copy for you to post directly online.

I don't think it's much trouble to get past the time limit for a youtube clip. I've watched entire movies on youtube before, the trick is just to break the video up into shorter youtube clips so you'll have "strange sex: episode POIS Part 1", strange sex: episode POIS Part 2",...part 3, ...ect...

Good idea, Vincent. I'll find that out.

[Vincent M]

Dan, PM me anytime. I just sent you a PM so you can just reply to that.

[Vincent M]

Of course, uploading commercial broadcasting onto an account may cause it to no longer have "good standing" - Youtube are fairly fast at taking things down, obviously they don't want people uploading Hollywood blockbusters etc.

Forgot about this. So maybe youtube would just take our video down anyway. Well I guess we could always upload the episode on another site and either link to that site from our current youtube video or link to it from the naked scientists site.

[horizon]

I'll have important test results very soon on the specific IgE antibodies to seminal plasma proteins, which is seen in women with seminal plasma hypersensitivity.

For the last 2.5 months I've worked with Dr. Bernstein and the University of Cincinnati Allergy Laboratory.

Does seminal plasma protiens mean "no sperm"? That would be a very cool test!

Nice one limejuice, I like your style, drop in once in a while, but you make sure to drop great bombs on us.

So those protein, is he testing every seminal protein or just does known to affect women.
It would be nice if he can also test sperm without seminal protein  that would answer alot of question.

The test is comprehensive of the human immune system and includes all mediators - IgE, IgM, IgG, and T-Cells.  It should truely determine if POIS is a reaction to seminal plasma or something else.  After all the test is $2,000.

I wonder if you are the first on the forum to have this test done?

[horizon]

http://myhealth.hollandhospital.org/HealthTopics/allergies/dec07acMain.htm

Dr. Ronald Simon, an allergist at Scripps Clinic in San Diego , told HealthDay that he and his colleagues have treated patients with a mixture of contraceptive gel and an anti-allergy medication, cromolyn.

Thanks Horizon, I'll be contacting Dr. Ronald. 

dont forget to add the other clinic/doctors in san diego where you got the skinprick test done to the collaborators list.