[kurtosis]

Kurtosis, you said that "after several blood tests it's clear that, for whatever reason, my body is constantly fighting some allergy". What blood tests your doctor do?

RAST tests to determine IgE levels. I've had 2 tests done over the past few years and they all come back with elevated IgE levels. I got another one done recently and was told over the phone some of the results were high and to come in and discuss it. I seem to have a lot of strong allergies but they don't check specifically for POIS-related allergens as they don't know what POIS is

[Joe L. Ogan]

Please permit me to say that there is nothing wrong with having a psychological problem.  Please do not misinterpret this statement to mean that I believe the problem to be psychological.  With all due respect, is the problem more prevalent among people who have a scientific background?  This does not seem logical to me but, since the only people that I know that have it, are people with scientific backgrounds, it poses the question.  No offence meant to anyone.  Thanks for comments.  Joe L. Ogan 

[observercenter]

Please permit me to say that there is nothing wrong with having a psychological problem.  Please do not misinterpret this statement to mean that I believe the problem to be psychological.  With all due respect, is the problem more prevalent among people who have a scientific background?  This does not seem logical to me but, since the only people that I know that have it, are people with scientific backgrounds, it poses the question.  No offence meant to anyone.  Thanks for comments.  Joe L. Ogan 

Who do you know suffering from POIS ? I do not think that we could jump into this conclusion. I bet that thousands of men are suffering from POIS all over the world and they do not know what is happening to them. It could happen to anyone. I have a scientific background, but when I got POIS I had not, so why are you asking the question?
If I have an Orgasm I would suffer from severe cognitive impairment, lethargy, depression, brain fog, bad stomach, red eyes..., but if I take the niacin pre-O I will block the symptoms. If you met any of us, you will notice the difference very clearly. 

[kurtosis]

Please permit me to say that there is nothing wrong with having a psychological problem.

Perhaps there isn't but that is not our understanding of what we're going through.

Please do not misinterpret this statement to mean that I believe the problem to be psychological.  With all due respect, is the problem more prevalent among people who have a scientific background?  This does not seem logical to me but, since the only people that I know that have it, are people with scientific backgrounds, it poses the question.  No offence meant to anyone.  Thanks for comments.  Joe L. Ogan 

That's an interesting question. I don't know who else you know with POIS but the question arose on the other forum at http://poiscenter.com/forums/index.php?topic=55.0
It's unlikely there's such a small group of people globally with this condition so a more plausible explanation is that we gravitated to this forum because

1) We had jobs requiring analytical skills and memory above the "average" and we could see that POIS was compromising these abilities. In some cases severely.
2) The association between an orgasm and the cognitive impairment is difficult to make and even when you make it you tend to deny it for a while. Years in some cases. The desire to fix the problem comes from frequently facing the effects of POIS in a demanding job. Who knows how many others are feeling these symptoms but dismissing it as feeling "under the weather" or suffering from other stressors.
3) We're all able to use the internet to research things and in the same manner, we came upon this site. Many came from watching the video on youtube.

Given the small sample size and the unique nature of the interaction here (on a science forum) it's difficult to draw conclusions. However, there may be a correlation between our personality types, neurotransmitter levels and POIS. I don't know

[Joe L. Ogan]

Hi, Thanks for your explanation.  My thought that there are probably many men and women suffering from the problem.  They must feel very isolated and alone.  I can see where they may feel very despondent from the isolation.  If possible, I would like to see some effort to identify them and give them some encouragement that they are not the only ones with the problem.  I also wonder if it is more prevalent among men than women.  Thanks for comments.  Joe L. Ogan

[Mer]

Joe,

As soon as I have an O back of my throat start to get swollen. The bump gets so big that I hardly can swallow my saliva.

Could you please help me understand how can a physiological condition lead to this effects? After I get a wet dream while I'm sleeping, the next morning I have the same condition.

If you can help me to avoid this condition it will be great. For now, I will forget about brain fog etc. which are more cognitive.

Thanks!

[GoingCrazy]

Joe there is just no way that this problem is psychological.  I used to be able to "O" freely at any time that I wanted, as many times as I could.  Than one day -BAM!-  got hit by a POIS train and am still laying on the tracks wondering what hit me and how do I get off of these tracks.  The symptoms of POIS, at least my own symptoms, are so severely debilitating that if I take no supplements such as niacin or benadryl beforehand I will be in a state of torture for at least a day or two until symptoms subside.  It is twice as bad if I have to work.  There is no psychological explanation towards POIS.  How do you explain a burning sensation in the groin (have had that a couple of times) after orgasm?  How do you explain someones throat clogging?  Not by any psychological means.  It is purely a physical reaction causing all of these POIS symptoms.

[Mermaid]

Doesnt everyone know by now this is all about prolactin/dopamine? I am new to this post but I am not sure if that has been mentioned at all in the 709 previous pages but dont people know by now the cause of this illness is hormonal?!

The cause of POIS is most likely due to the surge in prolactin which stays elevated for days post orgasm. Prolactin counters dopamine, which causes tiredness, depression, anxiety, etc. So really, you are dealing with 2 problems. One is the side effects of high prolactin and the other is the side effects of low dopamine. Excess prolactin also can result in higher cortisol, blunted thyroid response, etc! Has no one has figured this out by now on this post?

I am actually a 22 year old female in college and have this so I am seeing a doctor to see about lowering prolactin levels. I didnt start suffering with this until 2 years ago so I am trying to put it all together. I am going to my doctors to see about getting an MRI to see if I have a prolactinoma. It makes sense to me that if I have a prolactinoma (tumour in my pituitary causing increased prolactin) that is already giving me high prolactin levels, then an orgasm, which greatly increases prolactin as well, could tip my system over the edge and just knock all dopamine down to nothing. So, if you have POIS, I suggest you see a doctor who can tell you whether you have high prolactin levels naturally, low dopamine/low testosterone/low progesterone/excess estrogen which all can leave one susceptible to prolactin, or some other condition like hypothyroidism that will make you not be able to tolerate the surge in prolactin post orgasm.

I really feel for you all I know this is super annoying. I didnt start connecting my symptoms to orgasm until recently but since I have stopped ummm...well you know! lol... I feel much better! Of course its just my luck that I had to have an orgasm in my sleep this morning and put me back at square one! UGH!!!!! But I will figure this out I am making an appt with a very good physician tomorrow that my school clinic recommended.

Hope this helps!
<3

[Prancer]

Thank you for that information Mermaid! What you said does make a lot of sense. I hope you figure something out tomorrow, and feel better soon!

[GoingCrazy]

Doesnt everyone know by now this is all about prolactin/dopamine? I am new to this post but I am not sure if that has been mentioned at all in the 709 previous pages but dont people know by now the cause of this illness is hormonal?!

The cause of POIS is most likely due to the surge in prolactin which stays elevated for days post orgasm. Prolactin counters dopamine, which causes tiredness, depression, anxiety, etc. So really, you are dealing with 2 problems. One is the side effects of high prolactin and the other is the side effects of low dopamine. Excess prolactin also can result in higher cortisol, blunted thyroid response, etc! Has no one has figured this out by now on this post?

I am actually a 22 year old female in college and have this so I am seeing a doctor to see about lowering prolactin levels. I didnt start suffering with this until 2 years ago so I am trying to put it all together. I am going to my doctors to see about getting an MRI to see if I have a prolactinoma. It makes sense to me that if I have a prolactinoma (tumour in my pituitary causing increased prolactin) that is already giving me high prolactin levels, then an orgasm, which greatly increases prolactin as well, could tip my system over the edge and just knock all dopamine down to nothing. So, if you have POIS, I suggest you see a doctor who can tell you whether you have high prolactin levels naturally, low dopamine/low testosterone/low progesterone/excess estrogen which all can leave one susceptible to prolactin, or some other condition like hypothyroidism that will make you not be able to tolerate the surge in prolactin post orgasm.

I really feel for you all I know this is super annoying. I didnt start connecting my symptoms to orgasm until recently but since I have stopped ummm...well you know! lol... I feel much better! Of course its just my luck that I had to have an orgasm in my sleep this morning and put me back at square one! UGH!!!!! But I will figure this out I am making an appt with a very good physician tomorrow that my school clinic recommended.

Hope this helps!
<3

Sorry mermaid, this is probably the most obvious and it's probably listed on page 2 of the forums (Lol sorry) but it isn't POIS (I believe).  Don't mean to sound like an a$$ but the prolactin/dopamine response is a normal reaction to sex.  Like I said, I used to be able to O freely, experiencing general tiredness after "O", (sign of prolactin doing its job).  Than when I got hit by a POIS train, like I said before, the post orgasmic feeling is not tiredness.  It's like a terrible migraine, feel like my head is going to explode from inflammation.  Feel completely irritable and imbalanced, my eyes turn bloodshot indicating a sort of reaction, sometimes I get a burning sensation in the groin, feel like I'm going to die from stress that shouldn't be there.  Sex doesn't relieve stress for me if I take no medications/herbs/vitamins before hand, sex is the stressor. 

Maybe it could be like a reaction to something like prolactin.

It's interesting to note though that you are a girl and if you have all of the general POIS symptoms that would be even more interesting.  It's also interesting that I am also 22 and am in college, maybe we could meet and talk about POIS  .

[acronym]

Mermaid, Quite a number of us have had our prolactin levels tested, and if it was as straight forward as that we would have wrapped this up. Early on I thought the same. My prolactin levels were normal (I saw the results). If prolactin was the culprit, how does it explain the massive bias for pois condition in males. 
Could you please do me a favour and list your sympoms with a little detail, and how long does it take after an O to get them, and how long before you are back to normal. Does sexual stimulation also result in you feeling worse?

[fidalgo]

Kurtosis, you said that "after several blood tests it's clear that, for whatever reason, my body is constantly fighting some allergy". What blood tests your doctor do?

RAST tests to determine IgE levels. I've had 2 tests done over the past few years and they all come back with elevated IgE levels. I got another one done recently and was told over the phone some of the results were high and to come in and discuss it. I seem to have a lot of strong allergies but they don't check specifically for POIS-related allergens as they don't know what POIS is

I had this tests when my POIS starts, 5 years ago, and all of them was normal...

[littledragon]

hi all,

here is a little info/update about my P.O.I.S. experience
I have been taking niacin tablets for 3 months now and I can say it really has minimized my P.O.I.S symptoms and I'm feeling like a newborn man
the only most important thing is that I really have to have a FLUSH, otherwise the 'nightmare' will still occur
this happened to me yesterday, when I took my standard 200mg
somehow my body didn't react to it (I think the reason was I didn't drink enough water) and I decided to take another extra 100mg
still nothing happened so I decided to get an 'O' (after 1 hour) because I did not want to take an overdose of niacin
30 minutes later as I went to bed, my P.O.I.S. symptoms came back!
after having a terrible night, without hardly any sleep, a burning feeling and a lot of toilet visits (I always drink a lot of water after my 'O'), I actually felt quite good today
the 300mg niacin did kinda do its job, although it was after the 'O'

so I recommend ALWAYS GET A FLUSH before 'O' and try to urinate afterwards as soon as possible to get a clean valve

[Joe L. Ogan]

It is my understanding that this is an alergic reaction to semen.  If this is true, why would a woman have the reaction with no  exposure to semen?  Thanks for comments.   Joe L. Ogan 

[ophicus1213]

[littledragon]

thank you for this interesting link!

[Joe L. Ogan]

It is my understanding that this is an alergic reaction to semen.  If this is true, why would a woman have the reaction with no  exposure to semen?  Thanks for comments.   Joe L. Ogan    Does anyone have an answer to this question?  Thanks for comments.  Joe L. Ogan

[makrofag]

A very very very bad video. What that guy is saying is complete bullshit and he seems to be a fraud as well. People cling to these irrational deficiency stories because it's the most comfortable excuse for their (psychological) problems.

[CertainlyPOIS]

It is my understanding that this is an alergic reaction to semen.  If this is true, why would a woman have the reaction with no  exposure to semen?  Thanks for comments.   Joe L. Ogan    Does anyone have an answer to this question?  Thanks for comments.  Joe L. Ogan

Because of that and some other reasons a good amount of us are skeptical of immune reaction theory that is why we are pushing for reasearch. 

But if we do find out it is totally because of semen allergy then we have to think of the fluids women also discharge.
Maybe they are also allergic to something in their fluid.  Even for the men we are not sure what specific component we are allergic to.

[Joe L. Ogan]

Has anyone applied the Scientific method of problem solving to this problem?  If so, I would be very interested in seeing the results.  Thanks for comments.  Joe L. Ogan