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COVID-19
Will the Oxford/AZ vaccine be tested at lower doses?
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Will the Oxford/AZ vaccine be tested at lower doses?
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katieHaylor
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Will the Oxford/AZ vaccine be tested at lower doses?
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18/12/2020 13:49:36 »
Barrie says:
Surely, there needs to be a dose response trial in the vaccine trials. If the (accidental) low first dose is effective then it could be that a second low dose could also be effective. This would reduce the overall amount of vaccine required considerably. Should there now be a test of even lower doses?
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Re: Will the Oxford/AZ vaccine be tested at lower doses?
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18/12/2020 15:10:14 »
There's still some debate about the "accidental" half dose. It seems that some shots were manufactured at half dose in error, but intentionally used as part of a dose-efficacy investigation that turned up with an unexpected answer.
IMHO this is not the time for much further investigation unless clinical practice turns up a lot of adverse reactions. At this stage the overriding priority is to minimise the effect of government incompetence and public stupidity by whatever means we have available.
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