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  1. Naked Science Forum
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  3. Cells, Microbes & Viruses
  4. How can we test new vaccines quickly?
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How can we test new vaccines quickly?

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Offline Bored chemist

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Re: How can we test new vaccines quickly?
« Reply #120 on: 17/07/2021 15:34:46 »
Quote from: acsinuk on 12/07/2021 22:12:31
voluntary common sense measures should be taken by people that feel vulnerable or at risk
But the precautions that actually work; wearing a mask and not going out if you are ill are not something that are in the control of the people who are at risk, are they?

Also, re "common sense":
This is the level of common sense we are talking about.
(And if you don't want to see  man with a smoke flare in his back passage, don't look at the video.)

https://videos.dailymail.co.uk/preview/mol/2021/07/12/4603711667086053302/636x382_MP4_4603711667086053302.mp4


If the risk was only to the idiots then you could just shrug and say it's evolution in action.
But, in this case, the morons are typically young enough to be more or less immune to serious harm from the virus.
But they spread it, recklessly, to others who are at grave risk.
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Offline alancalverd

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Re: How can we test new vaccines quickly?
« Reply #121 on: 17/07/2021 16:05:30 »
Just heard from my copilot for next week. I'll be flying solo as his "double-jabbed" son has just been pinged and found positive, so the family is in purdah. Now I would have thought that the banker son of a vet and a pilot, having received  a complete course of vaccinations, would be the sort of guy who by nature and nurture is better loaded than average with common sense and precautions. Problem is that the virus doesn't know this, and whoever infected him clearly isn't in the same precautionary league either.

All thanks to government ineptitude. Latest stats, with 80,000,000 vaccines delivered, show 48,000 new cases a day. Compare with Australia, one third of the population, with only 9,000,000 vaccinations: 100 cases per day. The difference: quarantine.

Vaccination sometimes works but doesn't prevent mutation or protect effectively against mutants. Quarantine always works and prevents mutants spreading.
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Offline Bored chemist

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Re: How can we test new vaccines quickly?
« Reply #122 on: 17/07/2021 16:18:22 »

Quote from: evan_au on 17/07/2021 02:13:52
Boris doesn't look like the bad boy any longer.
Boris can't really blame anyone else for this


* cases uk.jpg (41.35 kB . 717x402 - viewed 2917 times)
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Offline alancalverd

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Re: How can we test new vaccines quickly?
« Reply #123 on: 17/07/2021 16:28:23 »
Quote from: acsinuk on 16/07/2021 12:33:48
But if the checkin desk official thinks the passenger looks sick or unwell then I assume the management have the right or option to ask the passenger to take a covid test at no cost to the passenger and if it is positive then insist they rebook a week later flight at no cost to the passenger.
But what if you are returning from holiday and out of money??  Where will you stay and who will pay??

It has been the rule in all forms of public transport since the stagecoach, that the captain has the absolute right to refuse to carry any passenger who he thinks may endanger, inconvenience or infect others, without compensation. For the sake of efficiency this has been delegated to checkin personnel, train guards, etc., who carry the same absolute authority, and in many cases where the passenger's condition is temporary and involuntary, compensation is offered as a gesture of goodwill.

There may be plenty of goodwill around nowadays. Southend Airport usually handles some 650,000 passengers between January and July: this year, they handled just 550, but still have to pay the rent, fire crew, traffic controllers, security.....so they are offering flying schools "five landings for a fiver" just to keep the place ticking over between cargo flights.
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Offline acsinuk (OP)

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Re: How can we test new vaccines quickly?
« Reply #124 on: 19/07/2021 15:58:03 »
No-one has suggested we scrap vaccinations because they do not work against mutations.  Boris did not say that we should  not bother to self isolate if we are feeling unwell, or think we may be infectious.
These voluntary actions to protect our selves and others are totally and absolutely necessary but they are not compulsory any more which is a huge leap forward in getting our lives back to normal.
No-one in NHS can guarantee you will be alive tomorrow.!.     Living at all is a risk !!       Everyone has to die sometime!!!.
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Offline Bored chemist

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Re: How can we test new vaccines quickly?
« Reply #125 on: 19/07/2021 16:23:11 »
Quote from: acsinuk on 19/07/2021 15:58:03
Everyone has to die sometime!!!.
Yes, but most of us would prefer to postpone it.
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Offline Bored chemist

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Re: How can we test new vaccines quickly?
« Reply #126 on: 19/07/2021 16:24:05 »
Quote from: acsinuk on 19/07/2021 15:58:03
Boris did not say that we should  not bother to self isolate if we are feeling unwell, or think we may be infectious.
What Boris said was that he had been round a hospital, shaking hands with patients.
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Offline alancalverd

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Re: How can we test new vaccines quickly?
« Reply #127 on: 20/07/2021 00:28:02 »
Quote from: acsinuk on 19/07/2021 15:58:03
 Living at all is a risk !!       Everyone has to die sometime!!!.
I have asked you several times to name those of your family and friends who you wish to become infected. You have never answered, so I assume that you do not believe your own propaganda. That, at least, suggests a grain of sanity.
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Offline acsinuk (OP)

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Re: How can we test new vaccines quickly?
« Reply #128 on: 22/07/2021 11:35:06 »
Everyone in the whole world, including relatives, must get the covid virus until we all become herd immune.
 Just like the common cold most of us will hardly be effected particularly if we have been vaccinated. 
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Offline alancalverd

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Re: How can we test new vaccines quickly?
« Reply #129 on: 22/07/2021 12:32:46 »
But some will suffer chronic or permanent disability, and those of your family who you have selected but are not been prepared to name, will die prematurely from an extremely unpleasant and entirely preventable disease.

And there is no evidence that herd immunity is genetic, so future generations will continue to suffer.

But at least you won't be inconvenienced.
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Offline Bored chemist

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Re: How can we test new vaccines quickly?
« Reply #130 on: 22/07/2021 12:53:27 »
Quote from: acsinuk on 22/07/2021 11:35:06
Everyone in the whole world, including relatives, must get the covid virus until we all become herd immune.
Why?
I have an idea for you- cross out covid and put "smallpox" or "ebola" in its place and see if you still think it's a good idea.
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Offline Bored chemist

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Re: How can we test new vaccines quickly?
« Reply #131 on: 22/07/2021 12:55:32 »
And todays lesson.
How to evolve a virus to be immune to the vaccine.
Quote from: acsinuk on 22/07/2021 11:35:06
Everyone in the whole world, including relatives, must get the covid virus until we all become herd immune.
 Just like the common cold most of us will hardly be effected particularly if we have been vaccinated. 

That should do it nicely.

Are you a special advisor to Boris?
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Offline acsinuk (OP)

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Re: How can we test new vaccines quickly?
« Reply #132 on: 23/07/2021 11:10:34 »
My concern is Aussies and Kiwis they must get vaccinated in time for the rugby.  Forget quarantine; that just a stop gap measure.
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Offline Bored chemist

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Re: How can we test new vaccines quickly?
« Reply #133 on: 23/07/2021 11:14:19 »
Quote from: acsinuk on 23/07/2021 11:10:34
Forget quarantine;
So, you advocate forgetting the policy which is actually known to work.

You will struggle to sell that idea in the antipodes where they have kept infection and death rates down by doing the thing you say they should forget.

Do you enjoy being laughed at?
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Offline evan_au

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Re: How can we test new vaccines quickly?
« Reply #134 on: 23/07/2021 11:38:20 »
Quote from: acsinuk
My concern is Aussies and Kiwis they must get vaccinated in time for the rugby.
After an unvaccinated airport limo-driver in Sydney caught Delta strain, Australia has a a significant outbreak.
- New Zealand has taken in their welcome mat
- All of the professional ellipsoid chasers have escaped to any state that will have them.
- But I think it has really changed the discussion around vaccination
- People in Sydney are grumbling about a lockdown, but that is nothing compared to lockdowns in Melbourne (or the UK)
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Offline alancalverd

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Re: How can we test new vaccines quickly?
« Reply #135 on: 23/07/2021 17:18:02 »
Quote from: acsinuk on 23/07/2021 11:10:34
Forget quarantine; that just a stop gap measure.
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Offline hamdani yusuf

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Re: How can we test new vaccines quickly?
« Reply #136 on: 27/07/2021 03:53:27 »
Quote from: acsinuk on 08/02/2021 15:50:43
First UK, then South African and now Brazilian mutate.  We have got to get our act together and set up a fast track testing on guinea pigs who will not sue us if some side effects occur..  Any suggestions??
I think the most accurate and safe way is using organoids.
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Offline alancalverd

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Re: How can we test new vaccines quickly?
« Reply #137 on: 01/08/2021 18:31:02 »
Safe, but irrelevant. The problem with COVID is that it induces a systemic over-reaction (cytokine storm) rather than attacking any particular organ, and the entire system can move into an unsustainable condition. 
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Offline hamdani yusuf

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Re: How can we test new vaccines quickly?
« Reply #138 on: 03/08/2021 14:59:13 »
Quote from: alancalverd on 01/08/2021 18:31:02
Safe, but irrelevant. The problem with COVID is that it induces a systemic over-reaction (cytokine storm) rather than attacking any particular organ, and the entire system can move into an unsustainable condition. 
Then the organoids can be assembled from various types of organs to create more complex system.
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Offline alancalverd

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Re: How can we test new vaccines quickly?
« Reply #139 on: 04/08/2021 11:37:07 »
....like a live animal, perhaps? Cheap, self-replicating with just enough variability to be a useful test, and a very good model of a live animal.
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