Could the human disease Cholera be caused by a sick bacterium?

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Offline evan_au

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It appears that the Cholera bacteria Vibrio cholerae does not actually cause the symptoms of Cholera until the bacterium is infected by a virus (a bacteriophage), which carries the gene for Cholera toxin.


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Offline CliffordK

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It may well be effective, and might give longer lasting protection than the current vaccines.  But it certainly would need a lot of testing.  It could be very bad if more people ended up being colonized by the virus free cholera, then contracted the pathogenic version.

I wonder if phages would be a factor in other diseases. 

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Offline cheryl j

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Diptheria only produces the diptheria toxin when it's infected with a phage. There are probably others.