[syhprum (OP)]

I have two computers making 5 systems available i:e two windows 7 64 bit one windows 8.1 32 bit and two windows 8.1 64 bit.
My main computer running win 8.1 64 bit will not let me access the nature magazine with IE11 although all the other publications' I have listed are available and Nature is available with Google Chrome.
It is only on this computer with this system and browser that this happens !!
DISM and reloading IE11 via features does no good !

[syhprum (OP)]

Mystery solved ! They have changed the name to
 
http://www.nature.com/news/index.html 

But why four systems responded to the old URL but not the Windows 8.1 system on my regular computer is a mystery.

It could be that this system is from a different source than the others .

[CliffordK]

Odd.

How big is the change in addresses?  Is it possible that different systems use different default DNS servers?  But that should only affect top level address changes. 

A lot of information gets cached, but I thought that address caches are usually purged every time one restarts the browser.  Perhaps look at your browser cache settings.