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I've stumbled onto an interesting piece about Niacin, Adrenaline and a substance called Adrenochrome which is claimed to be hallucinogenic (people's experience with it confirms its effects). That kind of gave me an idea for the origin of the brain-fog and the whole batch of psychological effects (feelings of being disconnected from reality, problems with social contact and etc). http://www.orthomolecular.org/library/jom/1990/pdf/1990-v05n01-p032.pdfThe paper is mainly about schizophrenia but the main idea is that under certain circumstances the adrenaline in the blood breaks down into Adrenochrome which if present in higher amounts can cause certain effects on the human brain (possible brain-fog origin).It sounds wild I know but what is interesting that I've seen many times results of POIS people that many had abnormal noradrenaline levels (this maybe requires a proper search the forums). From what i've read in the paper and elsewhere the noradrenaline breaks down to adrenaline and that breaks down to adrenochrome. This is also very interesting because I personally felt that POIS was a very strong and long lasting flight-or-fight response to my orgasms but I grew used to the feeling so I've kind of forgot about the flight-or-fight aspect of it and just focused on the brain fog. But still the flight-or-fight base always manifested itself when I was eating food and my mouth was overly salivating or when I touched a hot object my body would react in an extreme manner. Does anyone else also felt or feel that there's a flight-or-fight aspect to the POIS? Anyway Niacin according to the paper is a substance that can protect the brain tissue against the effects of adenochrome. Victor kons. if you're reading this - could this be the reason while you were trying with your doctor other vasolidators that only Niacin or Xanthiol Nicotinate really worked in preventing onset of the POIS symptoms??? It's kind of suspicious that other pro vasolidators were not really working.
I tried some alpha blockers and my POIS was even worse  but never beta blockers !
You need 60mg of tryptophan to synthetize 1mg of niacin.(other co-factor for this synthesis : B6, B2 and magnesium. This is very interesting for me because I have a chronic magnesium deficiency and I have fasciculation, especially hours after orgasm )
Has anyone seen this? http://www.herballove.com/article.asp?art=171Serotonin level!
okay I've taken Niacin 2 times in a row. The first night I took 100mg right after dinner and an hour before orgasm. I didn't notice a flush, but I seemed to have more energy around the afternoon of the next day.The night after I took 200mg of Niacin about 10hrs after eating anything and an hour before orgasm. I definitely got a flush about 30min after I took the pills. My arms were completely red and hot and itchy all over as were my ears and feet. I had an orgasm right when the flush was wearing off and while I did feel tired right after I orgasmed, after I laid down for a couple minutes I noticed I could still think somewhat clearly, which I'm never able to do immediately after orgasm. I felt okay today, but I had another orgasm or two during the night so I'm not 100% yet. I do notice that today my physical energy and stamina are greatly increased. For instance my arms feel a lot lighter if I lift one up and all movement simply happens so much easier than usual. If these results happen every time I take niacin I will conclude that it is definitely worth taking regularly, perhaps once a week so my body doesn't get too used to it.
Pinhole glasses are good for POIS.
Horizon, can you please elaborate on that?
Has anyone thought about allergy tablets?I have also been reading about a drug called Fexofenadine, its an allergy fight drug that says it takes away some of the symptoms we suffer from. I will take it and let you guys know how i feel.
Dont forget to Post on the other forum if you want your topic to be discussed in greater detail.
Quote from: horizon on 21/08/2011 18:32:15Pinhole glasses are good for POIS.Quote from: demografx on 21/08/2011 21:40:59Horizon, can you please elaborate on that?yep, i get about 50%+ [POIS] relief wearing them..until i take them off
Quote from: horizon on 23/08/2011 09:45:13Quote from: horizon on 21/08/2011 18:32:15Pinhole glasses are good for POIS.Quote from: demografx on 21/08/2011 21:40:59Horizon, can you please elaborate on that?yep, i get about 50%+ [POIS] relief wearing them..until i take them offhttp://en.wikipedia.org/wiki/Pinhole_glasses