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Quote from: Vandemolen3 on 09/08/2010 22:08:55Stress might be a factor. The famous Britisch writer Jane Austen died because of the dissaese of Adison. That's a dissease when the drenal cortex doesn't produce enough cortisol and aldosterone. She died in the 19th century, so no worries. Nowadays that can't cure Adison, but they have a treatment. Adison is rare, 120 per million people. During a stressful situation into the adrenal glands normally cortisol, which enables the body to deal with that situation. In people with Addison's disease can be very serious stressful situations lead to a crisis of Addison and a shock.With POIS you don't get a shock. But an O might be a stressfull situation for the body. So I am in for the cortisol theory. Does someone know which vitamins/pills you can use for a shortage of cortisol? Something you can buy without perscription. We all have too experiment a bit. Offcourse we have to be carefull. I ordered Fenugreek and Mecuna Pruriens. P.S. Or is the opposite with POIS: drenal cortex makes too much cortisol after an O? Stress is a factor of a lot of diseases (cardiovascular, cancer, immunity, diabete ) because stress hormones like cortisol have an effect on a lot of system (digestive, hormonal, nervous and immune systems). So of course stress is a factor.What is specific to Pois is the real question.I think orgasm causes a release of inflammatory agents (not a shock), following the inflammatory cascade schema. It seems confirmed by the 3rd study, recommanding usage of Nonsteroidal anti-inflammatory drugs.Then, the inflammation cascade is regulated by anti-inflammatory hormone cortisol, causing a temporary depletion, maybe not cortisol itself but several hormones (DHEA, progesterone). I think adrenal glands have double job : release of sexual hormones by orgasm (testosterone homeostasis (chinesisch study) and DHEA increased x5 according to american neurosexologist ) and regulation of inflammation by cortisol. So the adrenals are "tired" after orgasm. It works like an Addison crisis but of course our adrenals are physically normal. If someone has a flu every week, I think it's a normal thing that adrenals are tired. Some naturopath think adrenals glands are tired after winter because of cold and flu. Even if it's not scientific, I think the reasoning is not stupid.Some Pois have progesterone deficiency because progesterone is cortisol precursor. It explains carbohydrates sensivity too. I saw a big difference in my Pois when I stopped sugar.
Stress might be a factor. The famous Britisch writer Jane Austen died because of the dissaese of Adison. That's a dissease when the drenal cortex doesn't produce enough cortisol and aldosterone. She died in the 19th century, so no worries. Nowadays that can't cure Adison, but they have a treatment. Adison is rare, 120 per million people. During a stressful situation into the adrenal glands normally cortisol, which enables the body to deal with that situation. In people with Addison's disease can be very serious stressful situations lead to a crisis of Addison and a shock.With POIS you don't get a shock. But an O might be a stressfull situation for the body. So I am in for the cortisol theory. Does someone know which vitamins/pills you can use for a shortage of cortisol? Something you can buy without perscription. We all have too experiment a bit. Offcourse we have to be carefull. I ordered Fenugreek and Mecuna Pruriens. P.S. Or is the opposite with POIS: drenal cortex makes too much cortisol after an O?
Some Pois have progesterone deficiency because....
Quote from: Dean93 on 09/08/2010 23:47:45Quote from: demografx on 09/08/2010 15:54:06Health page writeup on POIS!http://www.tandurust.com/sexual-health/postorgasmic-illness-syndrome.htmlGents, we're coming out of the Dark Ages of POIS!! How exciting!This is great, but there are some things that I'm not so sure about such as:Some experts believe that relational and psychosomatic issues play a vital part in POIS.Sure, many doctors think that, but are they really experts? It's a little misleading.Doctors are experts in matters of health.Vasopressin has recently mentioned on the forum as it it released during sexual arousal and plays a role in Orgasm.We have no knowledge as yet whether it directly effects POIS either way, but this study in mice shows how Vasopressin/DNA can be effected by early trauma.http://www.modernghana.com/lifestylethread1/1188/16/You could also google Vasopressin and Oxytocin to find out there role/links in memory function.
Quote from: demografx on 09/08/2010 15:54:06Health page writeup on POIS!http://www.tandurust.com/sexual-health/postorgasmic-illness-syndrome.htmlGents, we're coming out of the Dark Ages of POIS!! How exciting!This is great, but there are some things that I'm not so sure about such as:Some experts believe that relational and psychosomatic issues play a vital part in POIS.Sure, many doctors think that, but are they really experts? It's a little misleading.
Health page writeup on POIS!http://www.tandurust.com/sexual-health/postorgasmic-illness-syndrome.htmlGents, we're coming out of the Dark Ages of POIS!! How exciting!
I've taken 2 different anti-depressant(zoloft and cymbalta) and both made my POIS symptoms worst. So I know they're not the answer. Multivitamins and a few herbs didn't work as well. Today I went to my doctor and got a hormone test. Will get result by thursday. I'm just hoping to find something.
Reply from Dr Selwyn Dexter, author of British Medical Journal Case Report 2010Dear "dermografx" [sic] Thank you for your e-mail.I am pleased you found my article interesting.I became involved through my interest on coital headache which may be just part of the syndrome of POIS.I intend to become further involved with this subject.Thank you for your offer of help,which perhaps I can take you up on in the near futureBest wishes Selwyn DexterOn Wed, Aug 4, 2010 at 2:46 AM, demografx wrote:Dear Dr Dexter, I want to thank you for your great work in publishing the study, " Benign coital headache relieved by partner’s pregnancies with implications for future treatment." After 30+ years suffering, I have personally been helped greatly with testosterone replacement therapy. Some members at the forum are considering - under physician supervision - combination treatments of progesterone and testosterone. Let me know if there is anything we can assist you with. Best regards, "demografx"ModeratorPOIS (Post Orgasmic Illness Syndrome) Internet Forum, http://www.thenakedscientists.com/forum/index.php?topic=6576.0
I think that more members of this forum have to sign in at the POIS Map. Only then we can see of members are from the same country/state. If so, maybe two ore more members can make an appointment at the same hospital. If there are more patient who say they have POIS more doctors will take POIS seriously. The more doctors who look seriously at POIS how bigger the change to find a cure.I am already on the POIS Map. I am from the Netherlands.
Hi, two questions to consider:1) who has a lot of hair? does POIS affect more people with or without hair??2) I'm called "itsallgood" because POIS have had some positive effects on me. And I think it is one thing to help me cope with this horrible condition. Has anyone else can think on a positive thing that POIS brought with it?
Quote from: B_Jim on 10/08/2010 06:43:15Some Pois have progesterone deficiency because.... Do we know this for sure?Has anyone actually had this confirmed through testing?thanks
Anti-depressants, from my perspective, definitely don't help and deal with a different aspect of the brain and mood. Quote from: itsallgood on 10/08/2010 19:17:47Hi, two questions to consider:1) who has a lot of hair? does POIS affect more people with or without hair??2) I'm called "itsallgood" because POIS have had some positive effects on me. And I think it is one thing to help me cope with this horrible condition. Has anyone else can think on a positive thing that POIS brought with it?1) Yes, full head of hair, really hairy actually2) No, not really, except a whole different outlook on life. I do feel more serious than i used to and yes I can say i feel more "pure"I really do think stress was the cause of my POIS. And dealing with work for me is in the same area POIS occurs in my brain. It's funny, I also used to gamble a lot and play video games competitively (xbox 360 halo) when I was younger and developed POIS. When I gamble or play now, just sitting there with the adrenaline, it is in the same area as POIS and I get really stressed out like POIS, so i try to stay away from it (I'm a teenager not a 80 year old gamer, no offense to the 80 year old gamers, just don't want to give out the wrong impression :} ). Is this some type of adrenaline/stress related disease?
itsallgood, belated welcome to the POIS thread of The Naked Science Forum! Here are some POIS resources which may be helpful to you:Our POIS Information Website, built by "mat780", is here: newbielink:http://sites.google.com/site/POISwebsite/ [nonactive]Please see "B_Jim"'s POIS Summary of All Cases, here as well as others on the Web. This includes remedies that we have tested, and results. newbielink:http://www.thenakedscientists.com/forum/index.php?topic=6576.msg149009#msg149009 [nonactive]Filling out the POIS survey created by "Counterpoints" can help you to share more POIS information and details with others here, as well as with future outside researchers. newbielink:http://pois.olympe-network.com/ [nonactive]"Girlwind" has created an excellent POIS Video: newbielink://www.youtube.com/watch?v=UWBxAUC9k1g [nonactive]Our new POIS chatroom (realtime chat). Invite or visit another member(s) there, ANY TIME. We can all get to know each other better: newbielink:http://forums.delphiforums.com/POIS/chat [nonactive]First POIS Research Study, 2002We have a copy of the first formal medical investigation on POIS by Prof. dr. Marcel D. Waldinger,MD,PhD, and Dr. Dave Schweitzer, MD. Recent POIS Research Study, 2010CASE REPORTPostorgasm Illness Syndrome - A Spectrum of IllnessesJane Ashby, MRCP, and David Goldmeier, MRCP newbielink:http://www.thenakedscientists.com/forum/index.php?topic=6576.msg316781#msg316781 [nonactive]British Medical Journal Case Report, 2010Case study by Dr. Selwyn Dexter of a patient with a headache-featured POIS symptom treated with progesterone/norethisterone. newbielink:http://casereports.bmj.com/content/2010/bcr.10.2009.2359.short?rss=1 [nonactive]There are a couple of ways to get any or all of the above 3 studies: (1) if you want a PDF copy, send me a Private Message (PM) with your regular email address (use "AT" instead of "@" ) and I'll send you back the PDF. Or, if you prefer, (2) I can simply reply with a Private Message (no regular email needed) and provide you with a simple text version embedded in your PM.To send a Private Message, click on "Messages" at the top of this page. At the Messages page, click on "New Message". From that point on, it works just like posting a message here, except that it only goes to the person(s) you designate. Remember to put a quote around my name, i.e., "demografx".New York Times article,January 20, 2009MindSex and Depression: In the Brain, if Not the MindBy RICHARD A. FRIEDMAN, M.D. newbielink:http://www.nytimes.com/2009/01/20/health/views/20mind.html?_r=1&scp=1&sq=friedman%20sexual%20January%2020&st=cse [nonactive]- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -In addition to serving our own informational interests, the resources listed above can be useful for you to show our credibility to the medical world - which often shows little understanding and is sometimes skeptical of our condition: POIS has scientific underpinnings and POIS is not "just another psychological problem" related to sex - to be treated by the psychiatric/psychotherapeutic community. All of this information can greatly help you to fight the immediate reaction of some doctors: so just tell them, "IT'S NOT 'ALL IN OUR HEADS'! "Also, it can be helpful when dealing with medical professionals to point out the successful existence of our rapidly growing forum, which has already been referenced in respectable sources such as the British Medical Journal and wikipedia: newbielink:http://en.wikipedia.org/wiki/Postorgasmic_illness_syndrome [nonactive]For over 3 years, our POIS forum has attracted over 150 POIS sufferers worldwide who have posted here, plus over 700,000 page visits. Not bad for a rare malady!
Hi everyone. Should I do this? Please let me know! (This is from The Spoof writer) Hey, [demografx], I was thinking: Would you be willing to be the subject of a formal interview? I would publish it in The Spoof Magazine, which is free form.I always conduct interviews via email, so there is never any question as to the accuracy of quotes. I would ask for a signed release, and offer you the right of final approval before publication.I own all my work published on thespoof.com, and would of course grant you license to do whatever you'd wish with it, including unlimited license to publish for profit.Let me know and we'll discuss in greater detail, OK?Thanks.