[demografx]

Testosterone does not help my pois. im on shots 2x a wk and my level is 789 but still have the symptoms after orgasms. I also take an estradoil blocker now, becuase T converts rapidly into estrogen. my level was 105 a year ago, so i assumed thats why i felt so bad after orgasm. It wasnt the answer. Im a 47 yr old male.

My injections didn't work well either and my endo explained that the injections "spike" then drop precipitously, which is why I was put on patches. Patches (worn 24/7) simulate the way testosterone naturally flows throughout the system steadily, rather than violently swinging up, down and out - as my endo believes is the case with injections.

[demografx]

One theory I have is that - even if we're not low on testosterone, a boost might work nevertheless, for some people. I have just increased my dose 50%, with doc's approval. I just wrote to my endo to get his opinion on my theory.

Reply from my endocrinologist: "Blood levels may not reflect tissue sensitivity - so the only way to tell is to test that hypothesis."

What got me thinking about this is that 8 years ago, desperately seeking a cure for my POIS, I contacted a well-known sexology-researcher in Czechoslovakia, and his immediate reply to me - without knowing whether or not I was testosterone-deficient - was...."testosterone!"

[pauliebaby61]

demografx----
I have used androderm patches, but they did not work and  severly burned my skin. I also used compounded T and Testim, both DID NOT work and never boosted my T level like the injections do.Testim made me really nauseaous for days---terible product imo
I now do .375cc of T 2x a week and take a pill that blocks the conversion into estrogen. I seem to feel more manly and confident now and have tons of facial and body hair growth, which i never had before. I could try a higher dose, but i dont see it affecting the pois symptoms. It seems to mimic a depletetion of something, and then it slowly builds up over 1-2 weeks.

[demografx]

Paulie, many thanks for sharing that! As I mentioned, my theory may only apply to some sufferers...or maybe none.

But I find it hard to believe that I'm the only one whose POIS can benefit from testosterone.

Paulie, can you please explain, "It seems to mimic a depletetion of something, and then it slowly builds up over 1-2 weeks."?

Thanks again!

[GoingCrazy]

Does anybody have an idea towards why POIS is worse in the morning?  (at least for me)

[Defsync]

well taking copper after an O doesnt help. even with ADD meds softening the blow. what a terrible week at work... even got taken before the boss for screwing up. what do you say to him? "uh sorry I got POIS after having an O last weekend" ROFL

well POIS has made it into a 2009 book about intimacy

http://books.google.com/books?id=88EU4S8BhtoC&pg=PT125&lpg=PT125&dq=post+orgasmic+illness+syndrome&source=bl&ots=AAF1fQY8Yk&sig=VjbIa3HEljV3UmQQ98xaEO_2XYw&hl=en&ei=if6rSrTWEZLSMuCm2PIN&sa=X&oi=book_result&ct=result&resnum=29#v=onepage&q=post%20orgasmic%20illness%20syndrome&f=false

though after the mention of POIS she says "the usual cure" is to have more O's.

lol

(looks around naked scientists forums)

hmmmm i missed that "usual" cure somewhere....

[demografx]

Does anybody have an idea towards why POIS is worse in the morning?  (at least for me)

Mine's worse in the evening. My no-POIS/low-energy time is evening.

Maybe your no-POIS/low-energy time is morning?

[demografx]

well POIS has made it into a 2009 book about intimacy

http://books.google.com/books?id=88EU4S8BhtoC&pg=PT125&lpg=PT125&dq=post+orgasmic+illness+syndrome&source=bl&ots=AAF1fQY8Yk&sig=VjbIa3HEljV3UmQQ98xaEO_2XYw&hl=en&ei=if6rSrTWEZLSMuCm2PIN&sa=X&oi=book_result&ct=result&resnum=29#v=onepage&q=post%20orgasmic%20illness%20syndrome&f=false

though after the mention of POIS she says "the usual cure" is to have more O's.

lol

(looks around naked scientists forums)

hmmmm i missed that "usual" cure somewhere....

The author, "reuniting" aka Ms. Marnia Robinson, is a good friend of this Forum, she has been extremely supportive of us. Counterpoints and 1-2 others have reported the cure you mentioned, which is intermittent, i.e., it doesn't always succeed.

I just recently posted about the book:

Interesting new book

Marnia Robinson, aka "reuniting" has been a POIS Forum member for quite some time and has contributed quite a bit to us. She and her husband are world-class experts in sexual relationships. Her new book looks like it might give us some more insight into POIS:
http://www.reuniting.info/cupids_poisoned_arrow

                       

[GoingCrazy]

Does anybody have an idea towards why POIS is worse in the morning?  (at least for me)

Mine's worse in the evening. My no-POIS/low-energy time is evening.

Maybe your no-POIS/low-energy time is morning?

In the morning I wake up and just cannot "focus", and still feel like I'm dreaming for about an hour or two after I wake up.  No-Pois?  Sometimes when I wake up it feels like POIS has recharged itself during sleep, but so has my body.  Very awkward feeling.

[demografx]

No-Pois?

No-POIS: meaning a day when we're not in-POIS or recovering, i.e., a "normal" day.

[Pronobis]

URGENT DANDRUFF

Hi everybody,

I have posted a similar question several times but I haven't got a right answer.
I have a dandruff since a year ago. I have got some product and I can treat it easily. But after each ejaculation it comes back in worst way (some hours after the ejaulation). Please tell me if you have the same problem and could it be due to POIS.
Thanx

[Z_one]

Thx "Demografx" and "B_Jim" for the welcome.....

"Goingcrazy" I tried inserting the link but the forum is not accepting it...maybe it's too long or something,,,,,though B_jim has successfully accessed it, therefore I don't think they removed it !


Z.

[GoingCrazy]

I don't know if by chance or not, but stretching my neck out and rotating it circularly seemed to actually calm me down a bit during POIS.

[Defsync]

hmm a couple things in this I havent heard of, like ACTH-MSH peptides and opioid peptides

The neurophysiology of the sexual cycle.

from:http://www.ncbi.nlm.nih.gov/pubmed/12834016

"The cycle of sexual activity in men and women occurs in 4 phases--excitation, plateau, orgasm, resolution--which are guided by sexual desire. Male sexual activity is characterized by erection, seminal emission and ejaculation (orgasm), whereas female sexual activity is characterized by vaginal lubrication, erection of the clitoris and orgasm. These responses are under the control of numerous central and peripheral neural systems. The central supraspinal systems are mainly localized in the limbic system (olfactory nuclei, medial preoptic area, nucleus accumbens, amygdala, hippocampus etc.), in the hypothalamus and its nuclei (paraventricular and ventromedial nuclei). Neural information travels through the brain stem, the medulla oblongata, the spinal cord and the autonomous nervous system to the genital apparatus. While we have very detailed knowledge of the neural mechanism, which controls the function of the male and female genital organs, in particular those mediating erection, very little is known of the central mechanism involved. Nevertheless, several neurotransmitters and neuropeptides, such as dopamine, glutamic acid, nitric oxide, oxytocin, ACTH-MSH peptides, are known to facilitate sexual function, while serotonin, gamma-aminobutyric acid (GABA) and opioid peptides reduce it. At the level of the paraventricular nucleus a group of oxytocinergic neurons projecting to extra-hypothalamic brain areas, including the spinal cord, have been identified, which facilitate erectile function and copulation when activated and reduce both when inhibited. Although the majority of results, which have clarified the mechanisms involved, have been performed in males, it is believed that similar mechanisms are also operative in females."

[CertainlyPOIS]

any body ever try that querctin supplement, it is suppose to be antihistamine and help with energy. I think studies on it is still early though.
http://www.umm.edu/altmed/articles/quercetin-000322.htm

[Defsync]

I was listening to NPR today about chemo-brain (info here: http://www.cancerhelp.org.uk/help/default.asp?page=40136)

symptoms:
    * Memory loss – forgetting things that you normally remember     
    * Difficulty thinking of the right word for a particular object     
    * Difficulty following the flow of a conversation     
    * Trouble concentrating or focusing on one thing     
    * Difficulty doing more than one thing at a time (multi tasking)     
    * More difficulty doing things you used to do easily, such as adding up in your head     
    * Fatigue (tiredness and lack of energy)     
    * Confusion     
    * Mental fogginess

okay why am i mentioning this, well Jim mentioned cytokines before... the doctor being interviewed said that some of the people who exhibit these symptoms have high level of cytokines in their blood. And they dont know why the cytokines could be causing them.

There exists a Cytokine panel of blood testing that can be done, like this one: http://www.lef.org/Vitamins-Supplements/ItemLCCYT/Cytokine-Panel---IL1b-IL6-IL8-TNF-Alpha-Blood-Test.html

The Cytokines in chemo-therapy result from an auto-immune response. Maybe for some of us the POIS is a auto-immune reaction triggering large amounts of these cytokines to be released. Once I have the health insurance again, I am definitely doing to get this panel done after a few O's (god that will be a crappy week at work lolz =)

Even in healthy males, studies (like this one: http://content.karger.com/ProdukteDB/produkte.asp?Aktion=ShowAbstract&ArtikelNr=79409&Ausgabe=230291&ProduktNr=224176) have shown that an O causes an immuno reaction by the human body.

[GoingCrazy]

Defsync, how come those individuals dont experience POIS?



More info about cranberry...

I O'd about a week and 2 days ago and symptoms are slow in diminishing.  I just started drinking cranberry juice again and it almost brings about more POIS symptoms.  I don't know what is going on.  It could be helping or it could be hurting me.

[Defsync]

Defsync, how come those individuals dont experience POIS?

dont know for sure, tho from the looks of it the immuno reaction is very very low, compared to what the cancer patients experience post-chemo

[Finally]

I was listening to NPR today about chemo-brain (info here: http://www.cancerhelp.org.uk/help/default.asp?page=40136)

symptoms:
    * Memory loss – forgetting things that you normally remember     
    * Difficulty thinking of the right word for a particular object     
    * Difficulty following the flow of a conversation     
    * Trouble concentrating or focusing on one thing     
    * Difficulty doing more than one thing at a time (multi tasking)     
    * More difficulty doing things you used to do easily, such as adding up in your head     
    * Fatigue (tiredness and lack of energy)     
    * Confusion     
    * Mental fogginess

okay why am i mentioning this, well Jim mentioned cytokines before... the doctor being interviewed said that some of the people who exhibit these symptoms have high level of cytokines in their blood. And they dont know why the cytokines could be causing them.

There exists a Cytokine panel of blood testing that can be done, like this one: http://www.lef.org/Vitamins-Supplements/ItemLCCYT/Cytokine-Panel---IL1b-IL6-IL8-TNF-Alpha-Blood-Test.html

The Cytokines in chemo-therapy result from an auto-immune response. Maybe for some of us the POIS is a auto-immune reaction triggering large amounts of these cytokines to be released. Once I have the health insurance again, I am definitely doing to get this panel done after a few O's (god that will be a crappy week at work lolz =)

Even in healthy males, studies (like this one: http://content.karger.com/ProdukteDB/produkte.asp?Aktion=ShowAbstract&ArtikelNr=79409&Ausgabe=230291&ProduktNr=224176) have shown that an O causes an immuno reaction by the human body.

When I am in POIS I notice swelling in my Lymph nodes especially under the arms and the neck.  This occurs even If I don't ejaculate.
Also have a fever feeling in back neck and face.  Always felt like an immune reaction.  Like when fighting a bad cold or flu.


Purchasing the LEF panel will probably not be reimbursed by insurance so make sure you check first.  I paid for mine because I trust them and I don't trust the people in my health care plan.

[Dean93]

Does anyone think that it's worthwhile or even helpful to do a "colon cleanse" before starting a supplement for better absorption? Not some brand name cleanse, just something simple like psyllium husk, for an effect similar to goingcrazy's from eating very little during cranberry testing.