[CertainlyPOIS]

Thanks

hows the norethisterone going

i was about to ask the same thing.

[CertainlyPOIS]

demografx-   

Before using testosterone and you were on aderall did you still heal normally within 3 days.
Can i just get a brief description of your experience on aderall before testosterone.

Did aderall make a dent on pois, mental wise.

[nova]

I have been doing testosterone injections 2x a week for 1 year and sorry to say it does not make any difference in my POIS.
My T level is 800+ now.The symptoms are the same as when my T level was 150.Only difference is my mood is better and i have bulked up. Wear the same clothes but my weight went up 20 lbs.

Many who suffer from POIS do not have low levels of testosterone.  Discussions in this forum over the past few years suggest that while POIS in some is alleviated greatly by TRT, the problem for most sufferers seems to be more complex than just adjusting ones testosterone levels.  

[daveman]

I was wondering if anyone here experiences this:

When I am aroused I start to feel unwell before orgasm and this keeps on for a while sometimes even if I dont orgasm.
By unwell I mean: feeling weak, nausea and even abdominal cramp with diarrhea.

Didn't use to happen before, it seems to happen more and more as I grow older. (I am 30)

Sigh, meanwhile I am still trying to find an endocrinologist who will look into this seriously.

The only thing I can say is that I usually have "pre-indicators", like a few twinges in the bladder area (like near the semenal vessels) or testicles, but I don't give them much attention now.

Before I came to this forum and when I thought I was a rare bird to have this curse, I didn't know what was happening to me. My mind could imagine 1001 fatal things! Of course, any twinge any where near the whole groin area would cause me to re-think the whole "having sex" situation. My fear and confusion made me feel bad before I would even try to get close. Good erections where few and far between.

There's stil no cure and I'm still not positive exactly what is causing my POIS, but knowing that I'm not alone, and that it's not cancer or anything that will take me in the next few weeks (more likely to get run over by a car), I have been able to approach sex with a lot more calm. I've even venture so far as to develop a protocol that helps me both to "understand" what's happening and reduce my symptoms. I'm down to 1 to 3 days of symptoms. When I first got here it was more like 6 weeks.

There is a heavy emotional influence that comes from fear and being alone. Here you are among fiends and people who will understand you completely. And sisnce each of us has a slightly different POIS, if yours is more different than others, you're still among those who really understand!

[mister_z]

Thanks daveman, how did you achieve a reduction in symptoms ?

[Limejuice]

Thanks

hows the norethisterone going

The norethisterone is going well, but it's not the 100% cure I'm looking for.  POIS is quite mild, but other possible associated issues are bothersome like difficulty sleeping and sensativity to carbs.  Because other POISers experience these issues I'm inclined to believe they might well be.  I've grouped my conditions in the same category as John21 and CounterPoints.

I've certainly gained weight on progestin, which is typically quite difficult for me.

[demografx]

demografx-  

1. Before using testosterone and you were on aderall did you still heal normally within 3 days.
2. Can i just get a brief description of your experience on aderall before testosterone.

3. Did aderall make a dent on pois, mental wise.

1. I don't understand the question.

2. It lifted depression significantly.

3. Yes. Decreased brain fog.

Switched to a different stimulant 7 months ago.

[demografx]

I have been doing testosterone injections 2x a week for 1 year and sorry to say it does not make any difference in my POIS.
My T level is 800+ now.The symptoms are the same as when my T level was 150.Only difference is my mood is better and i have bulked up. Wear the same clothes but my weight went up 20 lbs.

Many who suffer from POIS do not have low levels of testosterone.  Discussions in this forum over the past few years suggest that while POIS in some is alleviated greatly by TRT, the problem for most sufferers seems to be more complex than just adjusting ones testosterone levels.  

While I dont think testosterone is a universal panacea, we need more research to see the impact on POIS if we augment testosterone regardless of current T-levels.

My endo believes injections (which I started with sketchy results) are less effective than patches or gel. The former "spikes" in and out of the system, while the latter delivers more uniformly and evenly throughout the body, mimicking the way natural testosterone delivers.

[CertainlyPOIS]

Thanks

hows the norethisterone going

The norethisterone is going well, but it's not the 100% cure I'm looking for.  POIS is quite mild, but other possible associated issues are bothersome like difficulty sleeping and sensativity to carbs.  Because other POISers experience these issues I'm inclined to believe they might well be.  I've grouped my conditions in the same category as John21 and CounterPoints.

I've certainly gained weight on progestin, which is typically quite difficult for me.

Do you use the progestin everyday or just when you about to o'd.

[CertainlyPOIS]

demografx-  

1. Before using testosterone and you were on aderall did you still heal normally within 3 days.
2. Can i just get a brief description of your experience on aderall before testosterone.

3. Did aderall make a dent on pois, mental wise.

1. I don't understand the question.

2. It lifted depression significantly.

3. Yes. Decreased brain fog.

Switched to a different stimulant 7 months ago.

For question 1.  Did your pois cycle still occur normally. The stimulant did not affect your pois recovery process.

[demografx]

OK, the cycle was the same, but depression was lifted a lot, so I felt better in/out of POIS. But yes, the POIS duration was as agonizingly long as ever (3-4 days). Amazing that I accomplished as much as I did over 30+ years!!

[Guthrie]

http://en.wikipedia.org/wiki/Refractory_period_(sex)

That sounds like a really great idea to me- linking refractory periods and POIS. Keep up the good work...

Yes, I agree.  In fact, there could be ways in which POIS sufferers could be very helpful for researching refractory periods, since in general it's easier to understand a complex system if you can find an instance where something goes wrong.  That is, while it can be difficult to understand how the 'normal' refractory period works, studying us 'abnormal' folks could highlight key components of the mechanism.  So, even if a researcher was only interested in the normal refractory period (which applies to large numbers of people), and didn't have any inherent interest at all in POIS (which applies to a much smaller proportion of the population), they should still want to study us!

[lauracostis]

 very interesting article for my progesterone(GnRH antagonist) theory

"antibodies against gonadotropin-releasing
hormone (GnRH) and destruction of enteric
neurons in 3 patients suffering from
gastrointestinal dysfunction"

http://www.biomedcentral.com/content/pdf/1471-230X-10-48.pdf


yes that right some people have antibodies for GnRH, and you can be tested for them. what are the symptoms as related to the article: IBS(chronic diarrhea, and neurological damage. many of the pois suffers on this site suffer from lose bowls during pois.

my entire theory about using progestin/testosterone to block the release of GnRH might have a little more merit to it.

remember that GnRH is released from the hypothalamus which tells the anterior pituitary to in turn release LH and FSH. the androgens Progesterone and Testosterone are antagonists of GnRH, they dont actually antagonize GnRH itself, but the release of it from the hypothalamus. this is important to remember because once you have O'd GnRH is released, once it is released P/T will not have any effect on GnRH, they only stop it from being released. i strongly believe that the hypothalamus releases large amounts of GnRH after an orgasm, with or with out sperm as a mechanism to ensure that sperm gets replaced. why not just release GnRH after every orgasm, 99.999999999% of the time the orgasm is accompanied by sperm.  the sensor to turn on sperm production only turns on when your sperm count is down to like 20 million Sperm/ml. it will probably be impossible to prove this since any tests taken about the physiology of a male orgasm will be accompanied by ejaculation.

this new information has made trying my theory of the P/T contraceptive to cure pois a priority. my doctor told me to give her 3 months to put somthing together, that was about a month or more ago. that would put my start date at the end of the summer. i cant be sure that she will come through for me, she never did my endo test, so i had to go to my GP to get it done.

i will figure out what i have to do to get my GnRH antibodies tested

[lauracostis]

here is a research article on serum testosterone levels after ejaculation.
the article is not free, it can be purchased for 36 dollars.
it seems like it might be a must have for our forum and our own research.

the abstract is short but very interesting


http://www.springerlink.com/content/ex81g84768642505/

[horizon]

nice find!

[horizon]

Lauracostis : I have the full study if you want.
http://www.zju.edu.cn/jzus/2003/0302/030219.pdf

did you already own it?
if so, i guess its been previously discussed on the forum then?

[ad75]

Hi B_Jim!

Yes, I take Centrum Advance with full multivitamins and minerals. It contains 100% of the RDA of Vitamin D.

I feel that my own POIS issues were largely due to chronic vitamin B deficiency (with the associated adrenal problems) and, looking at the general symptoms of this, I wonder if it may be contributing to other individuals' enduring symptoms such as brain fog and tingling fingertips (B12 deficiency causes tingling of extremities)?

Here is an article which details the effects of chronic vitamin B complex deficiency.

"CHRONIC VITAMIN B DEFICIENCY

Vitamin B deficiency can sneak up on you, because it doesn’t have to create serious health problems right away. In fact, medical researchers have discovered that very often there can be no detectable signs according to scientific instrumentation, that you are experiencing a deficiency. For example, “memory impairment due to vitamin B12 deficiency can precede blood symptoms of deficiency by years. Evidence that vitamin B12 deficiency accounts for some cognition deficits in older people comes from a study that revealed abnormal short-term memory in more than two-thirds of clients with pernicious anemia…The researchers recommend that a diagnosis of senile dementia should not be made, even in the absence of anemia, until vitamin B12 status is determined biochemically.” (Hamilton, p. 476) This means that it is possible that certain mental disorders can be directly attributable to vitamin B complex deficiency, and it is easier to first start replenishing stores of vitamin B complex than to begin treating difficult mental illnesses with drugs, therapy or psychological counseling.

When vitamin B deficiency becomes chronic (long-lasting), other problems can occur, including troubles with your adrenal system. The adrenal glands serve many purposes, but in relation to this topic, they are the back up system for making energy. When there is a chronic lack of vitamin B complex then the adrenal glands are called upon to produce quick energy by injecting certain hormones like adrenaline into your system so that you can cope with life. If this goes on for a long time, then the adrenal glands become impaired or worn out, leading to even more health problems." newbielink:http://chetday.com/vitaminbdeficiencies.html [nonactive]

[mat780]

Dear All,

We would like to continue improving our POIS website and the information we have for future research.

What we would like to implement now, with your help, is the POIS Map (using the technology provided by Google maps).
This, not only will let us have an approximation of the World distribution of people with POIS symptoms, but also will show you
if you have a neighbor with whom you could possibly start visiting the same physician, etc.

Take a look at our beta version of the POIS map in our website:
http://sites.google.com/site/poiswebsite/pois-map [nofollow]

The only information we ask for is your approximate location, so your privacy won’t be compromised in any way.

We just ask for the Country you live in, but if you want to give us your state, province, or city, it would be much better to have a better map.

There are already some Forum members there.

How can you join?  Just send me (mat780) a Private Message and I’ll be glad to include you.

Regards,
Mat

[demografx]

Lauracostis : I have the full study if you want.
http://www.zju.edu.cn/jzus/2003/0302/030219.pdf


ad75 : Does your vitamin supplement contain Vitamin-D too ?

--

Link vitamin-D and testosterone :
http://news.bbc.co.uk/2/hi/health/8493042.stm

Some sites claim semen contains vitamin-D but it's not clear.

Thank you B_Jim and Laurac!!

[demografx]

Dear All,

We would like to continue improving our POIS website and the information we have for future research.

What we would like to implement now, with your help, is the POIS Map (using the technology provided by Google maps).
This, not only will let us have an approximation of the World distribution of people with POIS symptoms, but also will show you
if you have a neighbor with whom you could possibly start visiting the same physician, etc.

Take a look at our beta version of the POIS map in our website:
http://sites.google.com/site/poiswebsite/pois-map

The only information we ask for is your approximate location, so your privacy won’t be compromised in any way.

We just ask for the Country you live in, but if you want to give us your state, province, or city, it would be much better to have a better map.

There are already some Forum members there.

How can you join?  Just send me (mat780) a Private Message and I’ll be glad to include you.

Regards,
Mat

Thanks, Mat!