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Post Orgasmic Illness Syndrome (POIS)

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Offline afghan666

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11780 on: 24/02/2011 08:40:13 »
Quote from: hurray on 24/02/2011 06:51:43
Quote from: afghan666 on 23/02/2011 15:08:07
Hello evryone,
   A thought came to my mind.we have guys in forum who react badly to alcohol.my face goes pale if i smoke cigarettes.we might be having a sensitive or weak LIVER.the liver is responsible for producing antibodies,amino acids,hormones,blood,affects balancing sodium and neurotransmitters.it controls cholestrol,etc.
  there must be a relation between pois,allergy,neurotransmitter imbalance and liver.
 Fenugreek has liver protective properties.
 Turmeric is a gud liver protectant.i ll be checking out herbs used for hormone balancing and herbs good for live
 By the way fenugreek+ginseng+sulbutiamine+gingko biloba+optimen tabs hav an enormous improvement in pois and i am O ing daily.the only thing am concerned is whether fenugreek's effect will last or if i might build up some sort of tolerance.???

Hi afghan666,

Good to hear that fenugreek (amongst other things) is helping you with your POIS. I have been taking it daily myself for a long time now, and it is the best way I have found so far to minimise my POIS symptoms. I don't think I have built up a tolerance to it, but everybody's body is different. Interesting to hear that it helps to protect the liver.

 
 Thx man. . . I guess the positive effects of fenugreek will not be fading anytime soon

  progresterone has helped alleviate pois symptoms of a member in our forum.
  progresterone is estrogen and i guess its used for women's problms.
  fenugreek too has estrogens and steroidal compounds.i m trying to find similar herbs.may be a combo of fenugreek and another (hormone regulating herb) could increase improvement.
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Offline afghan666

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11781 on: 24/02/2011 08:46:24 »
Quote from: hurray on 24/02/2011 07:29:39
Quote from: afghan666 on 23/02/2011 17:08:58
Quote from: demografx on 23/02/2011 15:55:38
We don't "know" there's a neurotransmitter deficiency. Testing is highly inaccurate. Some evidence, please.

 It has been tested by scientists that low levels pf dopamine causes depression,loss of focus,Adhd and parkinson disease.After an O ,our body is depleted of dopamine which also results in high prolactin levels.prolactin is a sex and dopamine inhibiting hormone....after an O the body signals the release of prolactin as the natural process of mating is job done.But in pois sufferer the prolactin is released in far greater amounts thus it affects our focus,causes depression,ADHD,etc.the abnormal release might be an organ insuffiency e.g kidney,liver,thyroid or adrenal gland.

 For more evidence please google out ''effects of low levels of dopamine''...i m using android handy...other wise i wud had sent the links....


Am trying to put a piece in the puzzle...it might be one secondary or may be tertiary effects in the pois complex....

 Daveman is right...i agree...

I was convinced for a long time that low levels of dopamine were responsible for my POIS - during the last few years I have used Selegiline, L-Tyrosine, and Bupropion extensively (not all at the same time  [:)]), and I have also tried cabergoline.

None of these drugs felt like they were fighting my POIS symptoms, and did little to alleviate them. I'm not saying that dopamine does not play a key part in POIS - the whole prolactin/dopamine reaction seems like an excellent way to rationalise why POIS happens, but I personally have had no luck exploring this avenue.

Ur still missing the whole its not just a single neurotransmitter.its a whole chain of events.
 Dopamine might be a part . . . .but we r missing the point where it all begins from.
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Offline horizon

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11782 on: 24/02/2011 09:25:34 »
van,
do you ever get 'minor'/or any POIS from...
(a)arousal alone?
(b)mastubation without ejaculation and NO fluids/leakage?
(c)or mastubation without ejaculation but SOME fluids/leakage?
(d)how do NEs compare to (b)?
thanks

« Last Edit: 24/02/2011 09:28:43 by horizon »
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Offline Vandemolen3

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11783 on: 24/02/2011 12:05:58 »
Horizon,
a) no POIS
b) a bit of irritation
c) 1 day POIS (symptoms not very heavy)
d) In don't have NE's.
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Offline daveman

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11784 on: 24/02/2011 12:14:14 »
Quote from: afghan666 on 24/02/2011 08:40:13
Quote from: hurray on 24/02/2011 06:51:43
Quote from: afghan666 on 23/02/2011 15:08:07
Hello evryone,
   A thought came to my mind.we have guys in forum who react badly to alcohol.my face goes pale if i smoke cigarettes.we might be having a sensitive or weak LIVER.the liver is responsible for producing antibodies,amino acids,hormones,blood,affects balancing sodium and neurotransmitters.it controls cholestrol,etc.
  there must be a relation between pois,allergy,neurotransmitter imbalance and liver.
 Fenugreek has liver protective properties.
 Turmeric is a gud liver protectant.i ll be checking out herbs used for hormone balancing and herbs good for live
 By the way fenugreek+ginseng+sulbutiamine+gingko biloba+optimen tabs hav an enormous improvement in pois and i am O ing daily.the only thing am concerned is whether fenugreek's effect will last or if i might build up some sort of tolerance.???

Hi afghan666,

Good to hear that fenugreek (amongst other things) is helping you with your POIS. I have been taking it daily myself for a long time now, and it is the best way I have found so far to minimise my POIS symptoms. I don't think I have built up a tolerance to it, but everybody's body is different. Interesting to hear that it helps to protect the liver.

 
 Thx man. . . I guess the positive effects of fenugreek will not be fading anytime soon

  progresterone has helped alleviate pois symptoms of a member in our forum.
  progresterone is estrogen and i guess its used for women's problms.
  fenugreek too has estrogens and steroidal compounds.i m trying to find similar herbs.may be a combo of fenugreek and another (hormone regulating herb) could increase improvement.

I wonder. If you found a good natural testosterone stimulator in parallel with the fenugreek you might be able to close in a little on the male contraceptive formula.

Sure it could temporarily reduce sterility, but completely reversible. (according to extensive tests made with the two substances administered directly). Something to try.. although the dosage and method of administration is quite different from the male contraceptives.

In the end, may not do anything but hey.... if fenugreek helps why not try one step further?

« Last Edit: 24/02/2011 18:08:07 by daveman »
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Offline daveman

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11785 on: 24/02/2011 18:20:28 »
I think it's a good angle, this of isolating the Type I and Type IV reactions. It definately suggests the need for a good Type IV test.

That is, for those with mostly brain-fog and mental type problems, we could fail the skinprick test, but it doesn't mean we're not on the right track.

From what I could make of the reports, slightly higher concentrations should go so far as to provoke the Type IV reaction... more full blown POIS symptoms including mental.

So approached with care and the right professional guidance, perhaps the same skinprick test could serve for Type IV verification.

In any case, it appears to me that the remedy is the same, whether TypeI, Type IV or both.... desensitization.

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How does Murphey do it??
 

Offline Green

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11786 on: 24/02/2011 18:45:56 »
I wish there was more information about the patients who went through with the desentisisation therpay, such as the intensity of symptoms, what they now experience and whether or not they've managed to elminate PE.
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Offline Habibou

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11787 on: 24/02/2011 19:19:58 »
Quote from: afghan666 on 24/02/2011 08:40:13
Quote from: hurray on 24/02/2011 06:51:43
Quote from: afghan666 on 23/02/2011 15:08:07
Hello evryone,
   A thought came to my mind.we have guys in forum who react badly to alcohol.my face goes pale if i smoke cigarettes.we might be having a sensitive or weak LIVER.the liver is responsible for producing antibodies,amino acids,hormones,blood,affects balancing sodium and neurotransmitters.it controls cholestrol,etc.
  there must be a relation between pois,allergy,neurotransmitter imbalance and liver.
 Fenugreek has liver protective properties.
 Turmeric is a gud liver protectant.i ll be checking out herbs used for hormone balancing and herbs good for live
 By the way fenugreek+ginseng+sulbutiamine+gingko biloba+optimen tabs hav an enormous improvement in pois and i am O ing daily.the only thing am concerned is whether fenugreek's effect will last or if i might build up some sort of tolerance.???

Hi afghan666,

Good to hear that fenugreek (amongst other things) is helping you with your POIS. I have been taking it daily myself for a long time now, and it is the best way I have found so far to minimise my POIS symptoms. I don't think I have built up a tolerance to it, but everybody's body is different. Interesting to hear that it helps to protect the liver.

 
 Thx man. . . I guess the positive effects of fenugreek will not be fading anytime soon

  progresterone has helped alleviate pois symptoms of a member in our forum.
  progresterone is estrogen and i guess its used for women's problms.
  fenugreek too has estrogens and steroidal compounds.i m trying to find similar herbs.may be a combo of fenugreek and another (hormone regulating herb) could increase improvement.

I have just bought fengreek, let's give it a trial ! I will aslo start the "Silodosin cure" soon, under my doctor advice, of course ;) :)
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Offline daveman

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11788 on: 24/02/2011 20:01:03 »
Quote from: Habibou on 24/02/2011 19:19:58

I have just bought fengreek, let's give it a trial ! I will aslo start the "Silodosin cure" soon, under my doctor advice, of course ;) :)


Try to separate the result of the two for better resolution.

Are you going to start the fenugreek now (first). I don't remember what kind of a "ramp-up" it needs. How many days (weeks?) before noticing effects for instance?

How long before you think you'll start Silodosin, and will you stop fenugreek beforehand? etc. etc.
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Offline dbfd588

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11789 on: 25/02/2011 01:01:13 »
I looked all over for Fenugreek today and couldnt find it anywhere. I got 2 more places to check. But I did start Ginseng Complext today and can tell some difference already. Really looking forward to the Fenugreek, anything to help with symptoms until a cure comes along! Anybody Tried Milk Thistle? Bought some but havent tried it yet. Kinda wanted to se what the Ginseng was gonna do. Ive only had 1 half a dose and so far im liking it.
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Offline hurray

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11790 on: 25/02/2011 08:20:19 »
Quote from: dbfd588 on 25/02/2011 01:01:13
I looked all over for Fenugreek today and couldnt find it anywhere. I got 2 more places to check. But I did start Ginseng Complext today and can tell some difference already. Really looking forward to the Fenugreek, anything to help with symptoms until a cure comes along! Anybody Tried Milk Thistle? Bought some but havent tried it yet. Kinda wanted to se what the Ginseng was gonna do. Ive only had 1 half a dose and so far im liking it.

It's reasonably popular as a natural remedy in "vitamin shops", since it helps nursing mothers to produce more milk for their babies.

You can also make your own - I visited the Indian district of my nearby city and was able to purchase Fenugreek seeds and dried Fenugreek leaves (labelled as Kasoori Methi). Put them in a food blender for a couple of minutes and you will have a large quantity of powdered Fenugreek.
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Offline hurray

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11791 on: 25/02/2011 08:43:38 »
Quote from: horizon on 24/02/2011 09:25:34
van,
do you ever get 'minor'/or any POIS from...
(a)arousal alone?
(b)mastubation without ejaculation and NO fluids/leakage?
(c)or mastubation without ejaculation but SOME fluids/leakage?
(d)how do NEs compare to (b)?
thanks



Quote from: Vandemolen3 on 24/02/2011 12:05:58
Horizon,
a) no POIS
b) a bit of irritation
c) 1 day POIS (symptoms not very heavy)
d) In don't have NE's.

These are excellent questions horizon - my answers would be very similar to Vandemolen3.
I would be interested to know if anyone on the forum has a different answer for question c)

Do you ever get 'minor'/or any POIS from mastubation without ejaculation but SOME fluids/leakage?

I have often wondered if the people on the forum who don't get any POIS without ejaculation also don't have any pre-cum prior to ejaculation?
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Offline Counterpoints

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11792 on: 25/02/2011 09:41:24 »
Quote from: hurray on 25/02/2011 08:43:38
Quote from: horizon on 24/02/2011 09:25:34
van,
do you ever get 'minor'/or any POIS from...
(a)arousal alone?
(b)mastubation without ejaculation and NO fluids/leakage?
(c)or mastubation without ejaculation but SOME fluids/leakage?
(d)how do NEs compare to (b)?
thanks



Quote from: Vandemolen3 on 24/02/2011 12:05:58
Horizon,
a) no POIS
b) a bit of irritation
c) 1 day POIS (symptoms not very heavy)
d) In don't have NE's.

Do you ever get 'minor'/or any POIS from mastubation without ejaculation but SOME fluids/leakage?


Well, the way you've phrased it ('ever' and 'minor'), it would be hard to categorically say no.  But generally, I do not get POIS symptoms after pre-ejaculate.
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Offline hurray

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11793 on: 25/02/2011 14:27:02 »
Good feedback Counterpoints, thanks. Finding consistent symptom patterns with POIS sufferers is difficult!
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Offline Habibou

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11794 on: 25/02/2011 14:34:26 »
I don't know how many days I have to take fenugreek to try an O daveman :s if Someone tried and got some results, what was the duration please? :)
I will try Silodosin in about a week, but since I am very exhausted and only can stay home, I will try cure fenugreek/dopastim/silodosin at the same time to see if I recover faster.
Then, after, I will stop Fenugreek or dopatism and see the results, and so on...
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Offline daveman

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11795 on: 25/02/2011 15:46:38 »
Quote from: hurray on 25/02/2011 14:27:02
Good feedback Counterpoints, thanks. Finding consistent symptom patterns with POIS sufferers is difficult!

Very difficult, and this is a good example of why. Normally we don't notice much if there is pre-ejaculate or not, just that we stopped before.

I'm in the category that doesn't get a reaction, at worst lovers-nuts which is even normal for non-POISers. But at one point a began to doubt, or thought that I was developing a sensitivity to no-"O" masturbation. But in the end it was something else. So it complicates even further. So many variables.

Anyways, with or without pre-ejaculate I'm OK. I'm also in the category that has fewer mental effects.

 
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Offline hurray

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11796 on: 25/02/2011 16:11:01 »
I tried an O after taking a one-off 8mg dosage of Silodosin. The first 5 or 6 "spasms" of ejaculation were completely dry - the last one contained some semen, unfortunately for me.

I see 2 ways to proceed here - one is for me to up the dosage of Silodosin for "one-off" use and see if that has any impact. The other is to repeat my tests with 8mg per day for 3 days before O and see if it stops ejaculation again.

I started taking off taking a couple of capsules of fenugreek and then having an O about an hour later, then taking some more. I started off having practically no POIS symptoms at all for a couple of weeks, then the POIS symptoms began to return periodically, although they were much less severe than before - this is still true today.

I should mention that I now take fenugreek every day, POIS or not - it always has a positive social effect on me, and is pretty cheap now that I mix my own  [:)]
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Offline hurray

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11797 on: 25/02/2011 16:35:07 »
Quote from: daveman on 25/02/2011 15:46:38
Quote from: hurray on 25/02/2011 14:27:02
Good feedback Counterpoints, thanks. Finding consistent symptom patterns with POIS sufferers is difficult!

Very difficult, and this is a good example of why. Normally we don't notice much if there is pre-ejaculate or not, just that we stopped before.

I'm in the category that doesn't get a reaction, at worst lovers-nuts which is even normal for non-POISers. But at one point a began to doubt, or thought that I was developing a sensitivity to no-"O" masturbation. But in the end it was something else. So it complicates even further. So many variables.

Anyways, with or without pre-ejaculate I'm OK. I'm also in the category that has fewer mental effects.


More good information Daveman. I'm in the mainly mental effects category myself. Yes, plenty of variables!


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Offline Vincent M

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11798 on: 25/02/2011 16:45:34 »
Quote from: hurray on 25/02/2011 08:43:38
Quote from: horizon on 24/02/2011 09:25:34
van,
do you ever get 'minor'/or any POIS from...
(a)arousal alone?
(b)mastubation without ejaculation and NO fluids/leakage?
(c)or mastubation without ejaculation but SOME fluids/leakage?
(d)how do NEs compare to (b)?
thanks



Quote from: Vandemolen3 on 24/02/2011 12:05:58
Horizon,
a) no POIS
b) a bit of irritation
c) 1 day POIS (symptoms not very heavy)
d) In don't have NE's.

These are excellent questions horizon - my answers would be very similar to Vandemolen3.
I would be interested to know if anyone on the forum has a different answer for question c)

Do you ever get 'minor'/or any POIS from mastubation without ejaculation but SOME fluids/leakage?

I have often wondered if the people on the forum who don't get any POIS without ejaculation also don't have any pre-cum prior to ejaculation?

My POIS symptoms are actually relieved if I masturbate or become aroused and don't ejaculate. I also become more energetic after, however I have barely any pre-cum. My POIS symptoms seem to be the most severe of anyone's on this forum as I have brain fog to a zombie-like state as well as intense physical pains to the point where I basically live in my bed. I believe this is because  my refraction period is too short which causes me to need to ejaculate multiple times a day, thus I am ALWAYS in a state of POIS.
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Taking ginger tea, fenugreek+tea/garlic, saw palmetto, huperzine, niacin, boswellia, and nutmeg.
 

Offline Habibou

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #11799 on: 25/02/2011 18:56:30 »
Quote from: hurray on 25/02/2011 16:11:01
I tried an O after taking a one-off 8mg dosage of Silodosin. The first 5 or 6 "spasms" of ejaculation were completely dry - the last one contained some semen, unfortunately for me.

I see 2 ways to proceed here - one is for me to up the dosage of Silodosin for "one-off" use and see if that has any impact. The other is to repeat my tests with 8mg per day for 3 days before O and see if it stops ejaculation again.

I started taking off taking a couple of capsules of fenugreek and then having an O about an hour later, then taking some more. I started off having practically no POIS symptoms at all for a couple of weeks, then the POIS symptoms began to return periodically, although they were much less severe than before - this is still true today.

I should mention that I now take fenugreek every day, POIS or not - it always has a positive social effect on me, and is pretty cheap now that I mix my own  [:)]

Thank you so much for your trials and results Hurray! :)
Yes, I do agree that Fenugreek is great anyways ! how many pills do you take daily? (2 per day for me, but I just started...)
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