[Counterpoints]

My Pois is very reduced now.
 

Why?

[nick2k22]

Defsynch those ideas look great.  Im a student and dont have any money yet. It would be great to hear about any trials with those or any other drugs.  

I agree with you man, I get POIS without any fluid expulsion as well.

I'm not totally sold on the immune system theory but I haven't ruled it out.

Is anyone taking any non-herbal medication they can report on in addition to silosidin?
Any drug trial reports would be excellent. (non-herbal please)

Thanks,
Nick

[Counterpoints]

If it turns out that I'm just swapping one problem for another, I may have to ultimately abandon Silodosin, but I will keep trying for now. Time will tell.

Yeah, I think you should stay with it. You might be onto something major with this. don't give up. I mean, there are lots of people who would trade some drowsiness for their full POIS symptoms. And the drowsiness could be temporary.

Yes, I agree--it could prove an important result.  That is, if silodosin can prevent POIS by preventing ejaculation, then even if you decide that the side effects are too burdensome, we'll at least have learned that POIS is caused specifically by ejaculation, and not by orgasm per se!

It's already been confirmed by Waldinger that POIS is caused by ejaculation- at least that seems to be the hypothesis he's going on.
The benefit of this could be a much faster remedy for those who suffer with POIS instead of waiting years for the desensitization treatment. Perhaps the both could be done in tandem.

This is what Waldinger says and it bothers me.  

Agreed.... we still know very little about POIS with certainty.  

[lauracostis]

I have heard low dose naltroxene [sic] is good for these conditions. Has anyone tried it?

Perhaps some previous discussions here about naltrexone can help:
http://www.google.com/search?q=naltroxene+POIS+site%3Ahttp%3A%2F%2Fthenakedscientists.com&sourceid=ie7&rls=com.microsoft:en-us:IE-SearchBox&ie=&oe=#hl=en&rls=com.microsoft:en-us:IE-SearchBox&&sa=X&ei=21hsTdP2KpDSsAPs5N3LAw&ved=0CBgQvwUoAQ&q=naltrexone+POIS+site%3Ahttp%3A//thenakedscientists.com&spell=1&bav=on.1,or.&fp=42ea6e12edc6080

naltrexone did nothing for me

regular dose naltrexone (50 mg/day) helped me somewhat.

I have been taking LDN for over a year.  I think it has helped improve my cognition by 30-40%.  I was able to do math after I started taking it.  It is also possible it could be a placebo effect.  If you have the means to see a doctor and get a prescription its worth a try.  As I remember reading that for people with autoimmune disorders it is hit or miss.  Either the individual gets superlative results which usually continue to improve the longer they take it, or nothing happens at all.  My personal opinion is if the drug is safe and you get a doctors prescription, giving it a try is better than sitting on your ass and die of pois.  Although, these days I have not tried a new drug in a long time.  My best prophylactic has been not to produce an O manually in about a year and a half.  For this reason and this reason only has it been possible for me to be doing clinical rotations in hospitals working to get my nurse practitioners license.

[janiv]

Hi All,

I have joined to this forum 1.5 months ago, it is my first post and it's amazing to find you...
I have pois for the last 15 years, the Strong symptoms come immediately post O' and the moderate ones are after being aroused [usually because morning erection and etc.] The most tough symptoms are the Chronic headaches,brain fog-causing me to be out of focus and memory problems and damaging my ability to think clearly, tieredness, breathing problems, Anxiety and the neck muscles that are killing me.

Anyways, I am writing you today for telling you a story about bad and silly experience that I had last weekend.
To make story short, I read in the forum about the positive affects that nutmeg has on pois, Therefore I decided to go and buy those nuts in the nearest market. I ate 1 whole nutmeg [It was so disgusting, bitter and even the look inside of that nut - it's like Capillaries and veins; What would'nt you do for elminating the bad condition you are at when you have POIS ??]
So, after 4 hrs I started to feel very weird, totally high, my eyes were very red, I felt like my head is exploding from the pressure and it became worse, I had strong heartbeats, BP and the worst was an ongoing weird feeling of Anxiety.
On that day my wife and I went for a dinner at my parents house; having a conversation with my uncle I realize that he talks and I am totally out, I do not have a clue what he was talking about and I do not remember even the sentence before, I was totally blackout. I told him that I am can't follow him and I feel bad, then we went to hospital, all checks were good and it took me 2 days to totally recover.

Folks, Pls be careful when you using anything that might hurt you; we are totally suffering from pois and sometimes we may do mistakes like I did, pls take care of yourselves and learn from my story.

I wish you all to be healthy,

Yours,

Janiv

BTW: I am not against people who use nutmeg, I am sure that in small amounts it may be safe/benefit.

[demografx]

I am not against people who use nutmeg, I am sure that in small amounts it may be safe/benefit.

janiv, thanks for your cautionary tale! You were lucky. Nutmeg can cause hallucinations, vomiting, epileptic symptoms and large dosages can cause death.

[John21 (OP)]

Hi All,

I have joined to this forum 1.5 months ago, it is my first post and it's amazing to find you...
I have pois for the last 15 years, the Strong symptoms come immediately post O' and the moderate ones are after being aroused [usually because morning erection and etc.] The most tough symptoms are the Chronic headaches,brain fog-causing me to be out of focus and memory problems and damaging my ability to think clearly, tieredness, breathing problems, Anxiety and the neck muscles that are killing me.

Anyways, I am writing you today for telling you a story about bad and silly experience that I had last weekend.
To make story short, I read in the forum about the positive affects that nutmeg has on pois, Therefore I decided to go and buy those nuts in the nearest market. I ate 1 whole nutmeg [It was so disgusting, bitter and even the look inside of that nut - it's like Capillaries and veins; What would'nt you do for elminating the bad condition you are at when you have POIS ??]
So, after 4 hrs I started to feel very weird, totally high, my eyes were very red, I felt like my head is exploding from the pressure and it became worse, I had strong heartbeats, BP and the worst was an ongoing weird feeling of Anxiety.
On that day my wife and I went for a dinner at my parents house; having a conversation with my uncle I realize that he talks and I am totally out, I do not have a clue what he was talking about and I do not remember even the sentence before, I was totally blackout. I told him that I am can't follow him and I feel bad, then we went to hospital, all checks were good and it took me 2 days to totally recover.

Folks, Pls be careful when you using anything that might hurt you; we are totally suffering from pois and sometimes we may do mistakes like I did, pls take care of yourselves and learn from my story.

I wish you all to be healthy,

Yours,

Janiv

BTW: I am not against people who use nutmeg, I am sure that in small amounts it may be safe/benefit.

Here is the danger of people gleaning posts and not reading the cautions. I feel bad that this happened, as I initiated the dialog, but to restate what we clearly stated, nutmeg is very dangerous if too much is taken.

Always research substances before you consume them, and ease into it if you are at all unsure of the correct amount to take.

[demografx]

Thanks, John!

[alphaq]

Hi all,

I am also a sufferer of POIS and as everyone else here, am rather disappointed that the medical community doesn't have a clue to this stuff, and Dr. Waldinger's theories being rather unconvincing.

Recently I encountered the concept of mercury poisoning through amalgams in dental fillings. I did quite a bit of research on it and the symptoms do seem, in many ways similar to what many of POIS sufferers go through. And it does in a way coincide with Waldinger's theory that people become allergic to their our semen, or in other words, the immune system has an adverse response to semen in the system. Supposedly, mercury poisoning has been reported to cause in some cases auto-immunity.

I'd like to ask how many of us have had dental amalgam fillings containing mercury?

* Raise your hand * if you do, as sort of a poll.

Best,
AlphaQ

[daveman]

Hi all,

I am also a sufferer of POIS and as everyone else here, am rather disappointed that the medical community doesn't have a clue to this stuff, and Dr. Waldinger's theories being rather unconvincing.

Recently I encountered the concept of mercury poisoning through amalgams in dental fillings. I did quite a bit of research on it and the symptoms do seem, in many ways similar to what many of POIS sufferers go through. And it does in a way coincide with Waldinger's theory that people become allergic to their our semen, or in other words, the immune system has an adverse response to semen in the system. Supposedly, mercury poisoning has been reported to cause in some cases auto-immunity.

I'd like to ask how many of us have had dental amalgam fillings containing mercury?

* Raise your hand * if you do, as sort of a poll.

Best,
AlphaQ

Yes unfortunately the proffesional medical community and others sell product with a smile while we trust to our core that everything must be safe.

There must be millions of people around the world that have mercury amalgam fillings, many more I would assume, than the number of POIS victims in the world.

So wereas we may all have mercury amalgam fillings, there are many more as well who also have them without sufering POIS.

You are right though, many of the symptoms are similar. We have wondered here on the forum at times if POIS in some way may make us more sensitive to health anomolies.

[Vincent M]

I'd like to ask how many of us have had dental amalgam fillings containing mercury?

* Raise your hand * if you do, as sort of a poll.

Best,
AlphaQ

There was a previous discussion of amalgam fillings on this forum at this link: http://www.thenakedscientists.com/forum/index.php?topic=6576.685;wap2

One of the members here, John21, got all his amalgams replaced but it failed to have any effects on his POIS.

I do have 2 or 3 silver fillings which may be amalgam, but after doing some research it seems unlikely that they are the cause of my POIS since many many people have amalgam fillings and very few people have POIS. Also there are some members here with POIS who do not have amalgam fillings.

[demografx]

janiv, and alphaq, welcome to the POIS thread of The Naked Science Forum!




Here are some POIS resources which may be helpful to you:


Our POIS Information Website, built by "mat780", is here:
http://sites.google.com/site/POISwebsite/

The POIS Information Website is home to the famous POIS Forum Compendium, written by "Pyropeach", and contains theories already discussed here and treatments that have both worked and failed.

Please see "B_Jim"'s POIS Summary of All Cases, here as well as others on the Web. This includes remedies that we have tested, and results.
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg149009#msg149009

"Girlwind" has created an excellent POIS Video:

Our new POIS chatroom (realtime chat). Invite or visit another member(s) there, ANY TIME. We can all get to know each other better:
http://forums.delphiforums.com/POIS/chat


* Most recent POIS Research Studies, 2011 *

If you will send Prof. dr. Waldinger an e-mail, stating that you have read his message on the Forum, at http://www.thenakedscientists.com/forum/index.php?topic=6576.msg340138#msg340138 and that you are willing to fill in a questionnaire, he will send you the copies of both 2011 research articles by return through email. At a later date, he will send you the questionnaire which, after having filled in, you should send him back by e-mail.
His email:
prof.dr.waldinger.pois@gmail.com

Prof. dr. Marcel D. Waldinger's website:
http://www.post-orgasmic-illness-syndrome.com/en/index.html


First POIS Research Study, 2002

We have a copy of the first formal medical investigation on POIS by Prof. dr. Marcel D. Waldinger,MD,PhD, and Dr. Dave Schweitzer, MD.

  
Recent POIS Research Study, 2010

CASE REPORT
Postorgasm Illness Syndrome - A Spectrum of Illnesses
Jane Ashby, MRCP, and David Goldmeier, MRCP
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg316781#msg316781


British Medical Journal Case Report, 2010

Case study by Dr. Selwyn Dexter of a patient with a headache-featured POIS symptom treated with progesterone/norethisterone.
http://casereports.bmj.com/content/2010/bcr.10.2009.2359.short?rss=1


There are a couple of ways to get any or all of the above 3 studies: (1) if you want a PDF copy, send me a Private Message (PM) with your regular email address (use "AT" instead of "@" ) and I'll send you back the PDF.

Or, if you prefer, (2) I can simply reply with a Private Message (no regular email needed) and provide you with a simple text version embedded in your PM.

To send a Private Message, click on "Messages" at the top of this page. At the Messages page, click on "New Message". From that point on, it works just like posting a message here, except that it only goes to the person(s) you designate.

Remember to put a quote around my name, i.e., "demografx".


New York Times article,

January 20, 2009
Mind
Sex and Depression: In the Brain, if Not the Mind
By RICHARD A. FRIEDMAN, M.D.
http://www.nytimes.com/2009/01/20/health/views/20mind.html?_r=1&scp=1&sq=friedman%20sexual%20January%2020&st=cse

- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

In addition to serving our own informational interests, the resources listed above can be useful for you to show our credibility to the medical world - which often shows little understanding and is sometimes skeptical of our condition: POIS has scientific underpinnings and POIS is not "just another psychological problem" related to sex - to be treated by the psychiatric/psychotherapeutic community. All of this information can greatly help you to fight the immediate reaction of some doctors: so just tell them, "IT'S NOT 'ALL IN OUR HEADS'! "

Also, it can be helpful when dealing with medical professionals to point out the successful existence of our rapidly growing forum, which has already been referenced in respectable sources such as the Journal of Sexual Medicine (Dr. Waldinger's study), British Medical Journal and wikipedia:
http://en.wikipedia.org/wiki/Postorgasmic_illness_syndrome

For over 4 years, our POIS forum has attracted over 200 POIS sufferers worldwide who have posted here, research on an additional 200 sufferers elsewhere on the internet, plus over 1,000,000 page visits. Not bad for a rare malady!

[demografx]

janiv, and alphaq, this post will help you find information about POIS that we have already discussed, by tailoring a Google search to this forum:


SEARCH THE FORUM WITH GOOGLE

We have an overwhelming amount of data: almost 4 years' worth of posts (over  10,000 posts!) from 150+ Forum members, and an additional 150 POIS sufferers found elsewhere on the Internet by Member B_Jim.

In the Google search box, type
whatever-it-is-you're-interested-in-finding-out[space]POIS[space]site:http://thenakedscientists.com/

for example, I tried
nocturnal emission POIS site:http://thenakedscientists.com/

and 740 results came up for "nocturnal emission" within the Forum.

be careful with spaces (you can use them before the word "site") and no-spaces (everything after the word "site")

Google even provides you results with the Message# for each result. But Message #'s do change, so be patient and look for the approximate Message#.

[demografx]

I'd like to ask how many of us have had dental amalgam fillings containing mercury?

There must be millions of people around the world that have mercury amalgam fillings, many more I would assume, than the number of POIS victims in the world.

So wereas we may all have mercury amalgam fillings, there are many more as well who also have them without sufering POIS.

There was a previous discussion of amalgam fillings on this forum at this link: http://www.thenakedscientists.com/forum/index.php?topic=6576.685;wap2

One of the members here, John21, got all his amalgams replaced but it failed to have any effects on his POIS.

I do have 2 or 3 silver fillings which may be amalgam, but after doing some research it seems unlikely that they are the cause of my POIS since many many people have amalgam fillings and very few people have POIS. Also there are some members here with POIS who do not have amalgam fillings.

I had fillings, yes, but no idea what they contained.

Daveman and Vincent Marcus' reply makes a lot of sense to me.

[alphaq]

I do have 2 or 3 silver fillings which may be amalgam, but after doing some research it seems unlikely that they are the cause of my POIS since many many people have amalgam fillings and very few people have POIS. Also there are some members here with POIS who do not have amalgam fillings.

The thing with amalgam fillings is that it doesn't have adverse effects on everybody but on certain people it does, and at times it's quite bad and causes symptoms related to autoimmunity (might be correlated to semen allergy). The severity of mercury poisoning is debatable, but there's definitely times where there's poisoning and it's affecting you in some way but not actually knowing it. I'm not saying that mercury toxicity and POIS are directly causal, but we shouldn't rule it out until we find someone people here that haven't had fillings at all.

[alphaq]

I'd like to ask how many of us have had dental amalgam fillings containing mercury?

There must be millions of people around the world that have mercury amalgam fillings, many more I would assume, than the number of POIS victims in the world.

So wereas we may all have mercury amalgam fillings, there are many more as well who also have them without sufering POIS.

There was a previous discussion of amalgam fillings on this forum at this link: http://www.thenakedscientists.com/forum/index.php?topic=6576.685;wap2 [nofollow]

One of the members here, John21, got all his amalgams replaced but it failed to have any effects on his POIS.

I do have 2 or 3 silver fillings which may be amalgam, but after doing some research it seems unlikely that they are the cause of my POIS since many many people have amalgam fillings and very few people have POIS. Also there are some members here with POIS who do not have amalgam fillings.

I had fillings, yes, but no idea what they contained.

Daveman and Vincent Marcus' reply makes a lot of sense to me.

If they were silver/grey in color then they most likely were a 50% mercury amalgam

[demografx]

I do have 2 or 3 silver fillings which may be amalgam, but after doing some research it seems unlikely that they are the cause of my POIS since many many people have amalgam fillings and very few people have POIS. Also there are some members here with POIS who do not have amalgam fillings.

The thing with amalgam fillings is that it doesn't have adverse effects on everybody but on certain people it does, and at times it's quite bad and causes symptoms related to autoimmunity (might be correlated to semen allergy). The severity of mercury poisoning is debatable, but there's definitely times where there's poisoning and it's affecting you in some way but not actually knowing it. I'm not saying that mercury toxicity and POIS are directly causal, but we shouldn't rule it out until we find someone people here that haven't had fillings at all.

Good point. Sometimes I think we get over-anxious to rule things out because there seem to be a million-and-one possibilities to explain POIS and we're...frustrated!

One thing that keeps me sane is to think about POIS vs. the common cold: how many hundreds of years and billions of dollars' research and still...........no cure?

[Vincent M]

It seems that Counterpoints previously stated that he has no amalgam fillings, but still has POIS. I do think finding more people with POIS but with no amalgams could be worth it.

[alphaq]

It seems that Counterpoints previously stated that he has no amalgam fillings, but still has POIS. I do think finding more people with POIS but with no amalgams could be worth it.

It's also interesting to note that POIS has many forms and in some cases, and it appears rather different from person to person. Some people experience symptoms that are more physical, some experience symptoms that affects the mental state more than physically, some both. Not to mention that there's also different recovery period lengths, as some of us take only a few days (and as short as one day) and some take weeks to recover.

The point is that the "POIS" that people experience might not be actually the same thing. This also implies that these symptoms are also likely to have different causes. But of course we hope for the sake of simplicity that we are experiencing the same illness and there will hopefully be one universal cure, at this point which I doubt.

Ultimately we can conclude that mercury poisoning possibly indeed would be something to look into. To look into this more though we need a more controlled study with an experiment group (those with amalgam dental fillings) and control group (those without) and investigate if there's any similarities (and differences) in symptoms, basically trying to identify common patterns (can't prove anything but might help). In this case, because a lot of us have mercury fillings, this can be identified as a probable cause, which is a good thing.

[Vincent M]

I agree, alphaq. Perhaps we should ask each member via personal message if they have mercury amalgam fillings or not?