[demografx]

Hi finally i got xantinol nicotinate tablet in my area. One tablet is 150mg. How many tablets i require to take. At what time . And in empty stomach or with food. Please help.

Hi Nathan,
1. I think you need 3 tablets, e.g. 450mg in total of XN (thats my dose, my dose for pure Niacin is 150mg and I think its average among the people on this forum). I recommend you to start from one tablet and see if your body reacts okay on it. After that increase dose to two and the next time to 3 tablets. When you will take 3 tablets you can try having an O.
2. You need to wait at least 1 hour after taking tablets and before O. More generally you need to feel the flush and then feel that its gone and only after that have an O.
3. You need to take tablets on empty stomach. This way tablets will be absorbed better and faster.
4. Of course you need to check with your doctor if this is okay for you to take this medications in these dozes. I'm not a doctor. I'm telling you just my experience which might be not suited for YOUR case. So, do it, consult with your doctor first.

Hope this helps,
Victor

Victor, THANK YOU for posting the caveats!

Anyone seeking to treat POIS with ideas from this forum should PLEASE do so under a physician's care.

Some of what we discuss here can be dangerous if not done with medical supervision!

SAFETY FIRST, PLEASE

[fidalgo]

Good Night people,
At first I want to ask sorry for my bad english... I am brasilian.

Yesterday I discover this Forum. You couldn't Know my happiness after that. I'm suffering about POIS about five years. When start I stay a lot of time in the internet looking for what could be because all the doctors said that what I have doesn't exist. And now I have the certainty that I'm not alone in the world.

I read some post in the Forum about what can be used to improve our POIS but I don't know if you are in a best ou worst position than me. My POIS start five years ago, when I was 20 years. My two first years I couldn't live. I stay all the time in my home and I always feel terrible and with the sensation I couldn't control my acts. Because the doctors said that my disease doesn't exist, I didn't explain my problem to the doctors. In some times even I think my problem must be other. So I went in a lot of throat specialistm because I have always sore throat because of POIS. And then, after I use a lot of anti-allergics, I found one that change my life. My POIS didn't over, I cotinue with a lot of sore throat, but the medicinal improve a lot my POIS. I ejaculate at the night, I use the medician, I have the symptoms of POSI, but in the next morning, after I get up, I have almost no symptoms.

The name the medicinal in Brasil is Nasonex (I don't Know if in other countries have the same name). The active substance is Mometasona.

I don't know if my improve in symptons is bigger than yours with other medicinal, but I think you must try.

Other thing: I want try other things with nasonex, because I always have sore throat, what do you think is the best you tried? I like the ideia of patches of testorene because it seem to me two tottally differents ways of improve symtoms e may be adittionals... What do you think?

Other time: Sorry for my english...

Hi, Did you have chronic sinusitis? Have you had allergy testing?
I have  a lot of allergies and nasonex is just one of several sinus medications I've tried. None has brought about total relief but they do make a difference.

Hi Fidalgo,

Are you sure that you are suffering from POIS?  Are you getting the symptoms immediately after ejaculation?
Why I asked this, your medications seems to be best for Sinsuits treatment and its effects i.e. allergy in nasals.
I undergone Sinus X-ray and found normal in POIS period and doctor told me that there was not problem in Sinus. 

But, I always has a doubt that there is something imbalance happening in nasal after POIS.  I noticed many times that, imbalance in Nasal will happen immediately after the ejaculation and it is a first trigger for me in POIS. Later within 2 to 3 hours, from nasal imbalance is spread to Brain, behind eyes, and sometimes in knees (very rare).

I just ordered Nasonex spray and it will reach me tomorrow morning.  My friend who is a wholesale dealer in pharma warned me that, Nasonex has severe side effects if used excessively such as Sore throat, vulnerable to attack of Viral fever, bacteria, cold, headche and other illness and he suggested me to take precautionary action to avoid these side effects.  So, I will take Himalays's septilin and Azadirachta indica.  Septilin will boost the immune system and it protects attack of other viral, bacteria and other illness. Azadirachta indica is a god of herbals and there is no end of benefit of this.  So, from tomorrow I am starting use of Nasonex along with above 2 precautionary medicine. 

If you suffer from other illness after curing of POIS in single day, I am advise you to use the above 2 as these two herbals medicine will boost the immune system and side ee diffffects to this is very rare and if so, it is very minimal.

Nathan, starts using Nasonex one time per day, tow aplications in each nostrils. Always use after ejaculate. I think that, if works with you, you going to see the improve in the first week...  I hope that works...

I going try something like the Himalaya too...

[demografx]

fidalgo, I cannot remember when my POIS started!

But it's like since you start to ejaculate?

I remember POIS symptoms 30 years ago. But my POIS could have started as far back as 50 years ago! (Sorry to disappoint all of you who thought I was a teenager : - )

I - like so smany others here - simply could not 'connect the dots' from sex-to-POIS-symptoms.

This is very common with POISers. Sometimes the day(s) after sex feels horrible and we just DO NOT know why!!

It often takes years - since there are no "warnings" about POIS from your doctors, teachers, the media, friends, family, etc. It is often difficult to see that we are extremely fatigued, brain fogged, etc., the morning after.........sex!

[victor.kons]

Hi finally i got xantinol nicotinate tablet in my area. One tablet is 150mg. How many tablets i require to take. At what time . And in empty stomach or with food. Please help.

Hi Nathan,
1. I think you need 3 tablets, e.g. 450mg in total of XN (thats my dose, my dose for pure Niacin is 150mg and I think its average among the people on this forum). I recommend you to start from one tablet and see if your body reacts okay on it. After that increase dose to two and the next time to 3 tablets. When you will take 3 tablets you can try having an O.
2. You need to wait at least 1 hour after taking tablets and before O. More generally you need to feel the flush and then feel that its gone and only after that have an O.
3. You need to take tablets on empty stomach. This way tablets will be absorbed better and faster.
4. Of course you need to check with your doctor if this is okay for you to take this medications in these dozes. I'm not a doctor. I'm telling you just my experience which might be not suited for YOUR case. So, do it, consult with your doctor first.

Hope this helps,
Victor

Victor, THANK YOU for posting the caveats!

Anyone seeking to treat POIS with ideas from this forum should do so under a physician's care.

Some of what we discuss here can be dangerous if not done with medical supervision!

SAFETY FIRST, PLEASE

Btw, the meaning of my reply to Nathan was to note the information that from my experience the dosage of XN need to be bigger than the dosage of Niacin. I think this information is important to safe person from failing with XN by blindly following all Niacin recommendations. But for sure person need to visit the doctor and discuss with him whether it is safe to take XN in such dosage for his situation.

Victor

[nathan123]

Hi what happen to this forum. Why this is not opening

[fidalgo]

Fidalgo, No I haven't noticed a problem with eating before bed. Eating before bed is something I actually do often.

When do you take the Nasonex and how much?

Also, What kind of cognitive symptoms do you experience? A lot of us in here experience confusion, slowed thinking, trouble being alert, social diffulties, and even depression.

I canīt describe my symptoms with POIS and I think the others feel that way. All the symptoms that you said I have too but I think is more than that. Itīs a total desregulation of my body. My cognitive symptons are all of that you say and I feel like a Zumbi, like a dream, like a ilusion. I donīt feel like Iīm a living a normal life, mas like Iīm out. I think thatīs impossible to describe the symptons for a person that donīt have the symptons because, before POIS, I had never experienced something likely. But, because you have POIS, I think you understand what Iīm telling to you about the symptoms. Nasonex help me a lot with them, but I canīt tell you that is better than the one you in this Forum use. I suggest you to experiment and say.

What is the medication that the people have better results in Forum... Iīm thinking in test Niacin or and Caritin... Which do you think I would try first?

[fidalgo]

Good Night people,
At first I want to ask sorry for my bad english... I am brasilian.

Yesterday I discover this Forum. You couldn't Know my happiness after that. I'm suffering about POIS about five years. When start I stay a lot of time in the internet looking for what could be because all the doctors said that what I have doesn't exist. And now I have the certainty that I'm not alone in the world.

I read some post in the Forum about what can be used to improve our POIS but I don't know if you are in a best ou worst position than me. My POIS start five years ago, when I was 20 years. My two first years I couldn't live. I stay all the time in my home and I always feel terrible and with the sensation I couldn't control my acts. Because the doctors said that my disease doesn't exist, I didn't explain my problem to the doctors. In some times even I think my problem must be other. So I went in a lot of throat specialistm because I have always sore throat because of POIS. And then, after I use a lot of anti-allergics, I found one that change my life. My POIS didn't over, I cotinue with a lot of sore throat, but the medicinal improve a lot my POIS. I ejaculate at the night, I use the medician, I have the symptoms of POSI, but in the next morning, after I get up, I have almost no symptoms.

The name the medicinal in Brasil is Nasonex (I don't Know if in other countries have the same name). The active substance is Mometasona.

I don't know if my improve in symptons is bigger than yours with other medicinal, but I think you must try.

Other thing: I want try other things with nasonex, because I always have sore throat, what do you think is the best you tried? I like the ideia of patches of testorene because it seem to me two tottally differents ways of improve symtoms e may be adittionals... What do you think?

Other time: Sorry for my english...

Hi, Did you have chronic sinusitis? Have you had allergy testing?
I have  a lot of allergies and nasonex is just one of several sinus medications I've tried. None has brought about total relief but they do make a difference.

But your allergis has relations with POIS? I had a little cronic sinusis but I only have symptoms after ejaculate. And I had never noticed nothing before POIS. I think some noise allergy and cronic sinusis has relations with POIS .. Allergies I just have some little ones...

[demografx]

Hi what happen to this forum. Why this is not opening

Hi, Nathan. Everything is fixed now (I hope). Thanks for your patience.

[nathan123]

Today i used nasonex refered by fidalco.He recommended to to take it after orgasm. But i have taken one hour before. Today after orgasm i not felt any symptoms of alergic flu,congestion in the nose,burning eyes,headche,feeling like i hitted by truck to head, burning in head. So i can say whatever the problem relate to allergic reaction wil not trigger at all. But i felt dull, sadness, less social interaction and brain fog @ minimum. .  I can say that earlier we have to experience two type of symtons one is related to allergysuch as eye pain, burning in head,nasal block, physical pain etc and and another is in brain such as fog, difficult to speak ,confusion, low concentration,  which may due to imbalance in hormone. the first one wil not trigger for of today and i think we can face the later symptoms easily.

[fidalgo]

Today i used nasonex refered by fidalco.He recommended to to take it after orgasm. But i have taken one hour before. Today after orgasm i not felt any symptoms of alergic flu,congestion in the nose,burning eyes,headche,feeling like i hitted by truck to head, burning in head. So i can say whatever the problem relate to allergic reaction wil not trigger at all. But i felt dull, sadness, less social interaction and brain fog @ minimum. .  I can say that earlier we have to experience two type of symtons one is related to allergysuch as eye pain, burning in head,nasal block, physical pain etc and and another is in brain such as fog, difficult to speak ,confusion, low concentration,  which may due to imbalance in hormone. the first one wil not trigger for of today and i think we can face the later symptoms easily.

Ohhhh, I'm very happy that works... I already buy the Himalaya product and I expect that work for my throat. I think the other symtoms you say going be better tomorow... In the next time I will try to use nasonex before ejaculate...

[demografx]

Today i used nasonex refered by fidalco.He recommended to to take it after orgasm. But i have taken one hour before. Today after orgasm i not felt any symptoms of alergic flu,congestion in the nose,burning eyes,headche,feeling like i hitted by truck to head, burning in head. So i can say whatever the problem relate to allergic reaction wil not trigger at all. But i felt dull, sadness, less social interaction and brain fog @ minimum. .  I can say that earlier we have to experience two type of symtons one is related to allergysuch as eye pain, burning in head,nasal block, physical pain etc and and another is in brain such as fog, difficult to speak ,confusion, low concentration,  which may due to imbalance in hormone. the first one wil not trigger for of today and i think we can face the later symptoms easily.

One hour before is interesting!

Although I am largely cured of POIS, I still get heavy nasal congestion immediately afterwards.

The nasal spray, Afrin, works (too well) for me, but please be careful if you try it. It can become dangerously addictive, with side effects that can make your congestion much WORSE. It was once strictly Rx, now it's over the counter.

I am a lifetime user of it, but feel it should have remained Rx. Big mistake to make it so easily available, in my opinion.

[demografx]

From my experience the dosage of XN need to be bigger than the dosage of Niacin. I think this information is important to save person from failing with XN by blindly following all Niacin recommendations. But for sure person need to visit the doctor and discuss with him whether it is safe to take XN in such dosage for his situation.

Victor

Let's all follow Victor's good example of posting caution and the need for safe medical supervision in reporting all POIS experiments.

Many people read this forum silently (without posting) and will follow our suggestions. So keep in mind that when ANYONE posts something here at the forum, we have a leadership responsibility to our readers.

Recommending safety to our readers is needed, as often as is practicable.

Thanks again, Victor!

[fidalgo]

From my experience the dosage of XN need to be bigger than the dosage of Niacin. I think this information is important to safe person from failing with XN by blindly following all Niacin recommendations. But for sure person need to visit the doctor and discuss with him whether it is safe to take XN in such dosage for his situation.

Victor

Let's all follow Victor's good example of posting caution and the need for safe medical supervision in reporting all POIS experiments.

Many people read this forum silently (without posting) and will follow our suggestions. So keep in mind that when ANYONE posts something here at the forum, we have a leadership responsibility to our readers.

Recommending safety to our readers is needed, as often as is practicable.

Thanks again, Victor!

I donīt understand, are you cured of POIS? Donīt you have nothing after ejaculate? What dou you use?

Thank you...

[jferr]

Fidalgo,

What is the one herb or medication that has helped you most with your cognitive symptoms of things being like an illusion and dulled?

[fidalgo]

Fidalgo,

What is the one herb or medication that has helped you most with your cognitive symptoms of things being like an illusion and dulled?

The medication is Nasonex. Nathan used today and said that helped him. Itīs a ordinary medication, but helped me a lot. After you used, tell me if is better or worst the other medications you have used for POIS. I need to know if have a better medication to me.... And Iīm looking for good medications for sore throat case by POIS.

Thanks

[matthiasmainau]

Hello.

First of all: This is a great forum.
Amazing how much work has been done!

As I am strongly suspecting that I also suffer from POIS
I am very interested in Dr. Waldingers papers.
I tried to contact him, but was not successful.
Could somebody send them to my mail address? matthiasmainau /at"/ yahoo.com
I don't wish to be unpolite, but how reputable is he?
The website which has been given here has not been updated for years.

Thanks and regards

Matthias Mainau

[demografx]

I donīt understand, are you cured of POIS?

Yes.

Click here. I have posted here extensively about my TRT (testosterone replacement therapy) success.

And if you search further, you will see several other forum members posting TRT-for-POIS successes:

Green
EDS
Nova
Demografx
Animus
Pauliebaby61
Dave23

If you are interested, find a good endocrinologist and study the fertility risks.

[demografx]

matthiasmainau, fidalgo, Vasian1980, and napkynbass, welcome to the POIS thread of The Naked Science Forum!  We believe that 2012 is POIS' Breakthrough Year! We hope to launch serious POIS Medical Research! A great time to be here!



**(If you have any technical questions, please feel free to PM (private message) Daveman or me -- or another forum member - - go towards the end of this welcome message (after the 5 available research articles are described) for instuctions on how to send PM. We'll be happy to explain!)***


If you haven't already done so, but would like to like to join the new forum,  send "daveman" a PM here at the Naked Science Forum.


Here are some POIS resources which may be helpful to you:

Click here to see Mat780's excellent YouTube POIS Channel!   Mat's YouTube videos include (1) our great new April 12 POIS TV Documentary! A must-see. And (2) The Learning Channel documentary, featuring our forum member "Animus"!

Click here to see The POIS reddit post!  Outsiders (non-POISers) spontaneously gifted NORD's POIS Research Grant $1,000+ from this reddit post. Thanks to "mellivora" and "CCconfucius"!!!

Our POIS chatroom (realtime chat). Invite or visit another member(s) there, ANY TIME. We can all get to know each other better:
Just click here first, and then look for "CHAT" button towards top of page, 4th button to your right!

Our alternate POIS Forum - architectural genius: "daveman" - for detailed subject-by-subject discussion!
http://www.POISCenter.com/forums/index.php
Our 5-year-old POIS thread here at Naked Science Forum will also always remain open for newcomers, for general unstructured discussion, and historical research of the 10,000+ postings here since 2007.

Our POIS Information Website, built by "mat780", is here:
http://sites.google.com/site/POISwebsite/

The POIS Information Website is home to the POIS Forum Compendium, written by "Pyropeach", and contains theories already discussed here and treatments that have both worked and failed.

Please see "B_Jim"'s POIS Summary of All Cases, here as well as others on the Web. This includes remedies that we have tested, and results.
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg149009#msg149009

"Girlwind" has created an excellent POIS Video:

Post Orgasmic Illness Syndrome "POIS": Case report

Authors:
Abdalla M Attia*, Magda H Al-Ziny, Hossam A Yasien
*Corresponding author: Andrology Unit, Minoufiya University, Shibin El Kom, Eygpt

For more info, check out emi_b's  SMF POIS thread:
http://poiscenter.com/forums/index.php?topic=191.0;topicseen


POIS Research Studies available Upon Request:

1. and 2. POIS Research Studies, 2011

These 2 papers reveal Dr. Waldinger's POIS autoimmune hypothesis and suggest one possible avenue of treatment.

3. First POIS Research Study, 2002

We have a copy of the first formal medical investigation on POIS by Prof. dr. Marcel D. Waldinger,MD,PhD, and Dr. Dave Schweitzer, MD.

   
4. Recent POIS Research Study, 2010

CASE REPORT
Postorgasm Illness Syndrome - A Spectrum of Illnesses
Jane Ashby, MRCP, and David Goldmeier, MRCP
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg316781#msg316781


5. British Medical Journal Case Report, 2010

Case study by Dr. Selwyn Dexter of a patient with a headache-featured POIS symptom treated with progesterone/norethisterone.
http://casereports.bmj.com/content/2010/bcr.10.2009.2359.short?rss=1


How to get any or all of the above 5 studies: send me or "daveman" a Private Message (PM) with your regular email address (use "AT" instead of "@" ) and we'll send you back the PDF(s).

To send a Private Message, click on "My Messages" at the top of this page. Then click "Send Message". From that point on, it works just like posting a message here, except that it only goes to the person(s) you designate.


New York Times article,

January 20, 2009
Mind
Sex and Depression: In the Brain, if Not the Mind
By RICHARD A. FRIEDMAN, M.D.
http://www.nytimes.com/2009/01/20/health/views/20mind.html?_r=1&scp=1&sq=friedman%20sexual%20January%2020&st=cse

- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

In addition to serving our own informational interests, the resources listed above can be useful for you to show our credibility to the medical world - which often shows little understanding and is sometimes skeptical of our condition: POIS has scientific underpinnings and POIS is not "just another psychological problem" related to sex - to be treated by the psychiatric/psychotherapeutic community. All of this information can greatly help you to fight the immediate reaction of some doctors: so just tell them, "IT'S NOT 'ALL IN YOUR HEAD'! "





It can be very  helpful to you when dealing with medical professionals to point out the
POIS' official listing, as recognized by the
National Institutes for Health (NIH), Office of Rare Diseases Research:

And in Europe: Orphanet now lists POIS on their website! - Click here!

POIS also appears in credible medical sources such as the Journal of Sexual Medicine (Dr. Waldinger's study), British Medical Journal and wikipedia:
http://en.wikipedia.org/wiki/Postorgasmic_illness_syndrome

For over 5 years, our POIS forum has attracted over 200 POIS sufferers worldwide who have posted here, research on an additional 200 sufferers elsewhere on the internet, plus our pages have been read nearly 2,000,000 times! Not bad for a rare malady!

Show some of this to your doctor - with pride! Chances are, YOU know FAR more about POIS than s/he does! Don't be intimidated by fancy diplomas. It's almost impossible for ANY one doctor to know much about POIS before you walk into his/her office. Unfortunately, it's up to YOU to educate THEM! And if you happen to find yourself with a disagreeable "student"-doctor (you're the teacher!), find another doctor. Quickly!

SEARCH THE FORUM WITH GOOGLE

We have an overwhelming amount of data: more than 5 years' worth of posts (over  10,000 posts!) from 200+ Forum members, and an additional 200 POIS sufferers found elsewhere on the Internet by Member B_Jim.

In the Google search box, type
whatever-it-is-you're-interested-in-finding-out[space]POIS[space]site:http://thenakedscientists.com/

for example, I tried
nocturnal emission POIS site:http://thenakedscientists.com/

and 740 results came up for "nocturnal emission" within the Forum.

be careful with spaces (you can use them before the word "site") and no-spaces (everything after the word "site")

Google even provides you results with the Message# for each result. But Message #'s do change, so be patient and look for the approximate Message#.

[demografx]

I tried to contact [Waldinger], but was not successful.

A common complaint.

Could somebody send [Waldinger] papers to my email address?

Sent.

[littledragon]

Yesterday-night I took 150 mg of niacine 1 hour before 'O' by following the procedures described here.
I couldn't get back to sleep because of this burning feeling in my neck and upper back.
Does anyone experience this same burning feeling in the back which lasts a couple of hours after 'O'?