[LAPOISSE2]

I started eliminating gluten about a month ago ; I'll not draw any conclusion and will continue the experience for at least an other month  ; The idea behind this is gluten could cause some kind of malabsorption which could lead to various kind of symptoms which are specifically more intense after Orgasm.

After years of investigation, I'm now 100% sure that digestion is a least involved in the POIS mechanism

On my list of the potential culprit, there is also carbs and FODMAP's

[A-Memo]

have you been sensitive to gluten !!?

[narohWnarohW]

Dear jferr,

My story is a lot like yours. Please read. I think you will be helped.

My "POIS" was very similar to yours in that it lasted for months after a single orgasm. It was ruining my life much like it was yours. What was the cause? Anxiety? Depression? Vitamin Deficiency? Autoimmune? Mental? NO TO ALL OF THOSE!! I took every vitamin imaginable, went to a phsycologist and two doctors who did not do much help, and even abstained. What finally worked?

I tried slow deep belly breathing while masturbating. Not only did I last much longer, but I even felt a pleasant "afterglow" feeling when I was done! I felt slightly lethargic and  tired but that was gone by the next day. I take minimal vitamins and have a very healthy diet. I tried the chlorella thing and I haven't noticed a difference.

Thank you for reading and the best of luck to you and everyone else!

[Thapelo]

Hello readers,

I think i figgerd something out. If you have information about this, or you think i am wrong, please post it + send it to me private

Many pois suffers take Niancine, (vit b3) as a suplement, a half an our before orgasme. I think i figgered out why this helps.
Tryptofaan, as well as Ninance are required to make seratonine. (this is a neurotransmitter which make people feel good and happy, the opposite of a depression).
I read that in the western dieet you are short of vit b3. So supplementing this, does make you more seratonine, which reduces the effect of POIS.
This is why taking 5HTP also reduce the pois symptoms, like depression and anxiety.
Another point you might think is interesting, is that Niancine make you absorb your food better, which might reduce the diarree effect.

I just think all of this by reading some stuff,
notice, it is just an idea, if you have suggestions please also send me a private message so i can go further with my own "research"

Thank you for reading,

[LAPOISSE2]

Hey Lars,

I noticed that already and i believe serotonin is involved in POIS ; i've taken SSRI for two years with at first a total suppression of my symptoms.

That being said, I dont' think that the mechanism is that simple ; the niacin you ingest to produce serotonin after 30 minutes, it should have to inhibitory/protective effect somehow.

My experience with niacin has never been conclusive but I need to give other tentatives ; 5HTP helped me.

[gondal4]

what about the research?where r the results?

[Thapelo]

Hey Lars,

I noticed that already and i believe serotonin is involved in POIS ; i've taken SSRI for two years with at first a total suppression of my symptoms.

That being said, I dont' think that the mechanism is that simple ; the niacin you ingest to produce serotonin after 30 minutes, it should have to inhibitory/protective effect somehow.

My experience with niacin has never been conclusive but I need to give other tentatives ; 5HTP helped me.

Dear Lapoisse,

Niancine does more than just make seratonine, it reduces the effect of inflammation, which reduce the allergic reaction. This might be the protective effect of niacin.
Ill try 5htp for a while.
Thanks for sharing your experience.

[A-Memo]

hi , anybody knows the mechanism of being POIS with  kind of hypersensitivity reactions to caffiene and grains (hypersensitivity that disturb the whole day not just for hour and then it is relieved Okay !   ) , i really dont understand how this evolved it is a rare disorder that i cant understand.Any thing that i eat which release dopamine am sensitive to it , i think there is a defect which is related to the three of them ,, or if the defect in the immune sysytem then why am sensitive to all of these , note that i dont have any other manifestation of sensitivity except nervous maifestation  i dont have any kind of skin rash or anaphylaxis to any of them i just feel depressed and anxious after ingestion of caffiene , all grains except rice and then come the pois  which is not ingested  [] ,, any ideas guys ? , or any one have the same manifestations ? if some one has the same plz i to talk to him regarding this . cause never heard about person who have POIS and caffiene sensitivity at the same time !!   any person who has nervous sensitivity to stimulants or grain plz contact me privately or post a commet 

[gondal4]

New symptom since last 7 months ejaculation never stops after orgasm untill i urinate

[MrVat7]

Poisers may have a sudden fall in dopamine after an orgasm...symptoms says.

[FinalPanic]

A-Memo - I have terrible problems with caffeine. If I drink a regular ground coffee I very quickly develop seriously heightened anxiety - bordering on panic. This can last for hours - once I come down I feel absolutely exhausted - I will be anxious and trembling for rest of the day. I have had pois symptoms for over 30 years now. I manage it as best as I can. I developed anxiety problems when about 19 whilst suffering terrible insomnia. This just made me feel so ill. Any stimulants - coffee, alcohol, cigarettes all had an amplified effect on me. I was ok before my sleeping troubles. Then my trouble started and BAM - all over the place. Pois started during this period. It seems obvious to me that my body is all messed up - anxiety being caused by wayward body chemistry, intolerance of any stimulants which cause hugely exaggerated effects - I can avoid the obvious stimulants but avoiding orgasm is a bit of a tall order. I really do think that pois is a bodyshock to a weakened and perpetually over stimulated nervous system. Body just cannot cope and goes haywire. I believe that if I could unwind my anxiety that my pois would too subside - but that is easier said than done. Anxiety is a compounding condition for me - worry creates worry. I get anxious about feeling anxious. It becomes a self-fulfilling prophecy. It becomes part of your make-up - I live in a constant state of exhaustion, but I am honest with myself. I have tried many of the suggestions on here. They do not work for me as they do not treat the core problem. Having said this I am in a relationship, have a daughter, run a business - it takes determination but it is all do-able. As I have aged my pois symptoms are lasting longer - going from a very bad hit for a day or two, to less intrusive symptoms that now last over several days - usually 7 to 10. Thing is having more orgasms during pois does not make it worse.

[A-Memo]

Thanks Man , ur description of your state and condition is so comprhensive , it seems like there is a combination of congenital factors , hormone receptors secretions etc...  and as u said an enviromental factor which is the surrounding atmosphere of anxiety and stress ,, and the things that exaggerate the conditions are the stimulants , now i cant consume caffiene any more i get anxiety and pooor sleep and am sure it is a kind of hypersensitivity reaction cause when i avoid those stimulants i feel better some how but again the main core process of the illness is still unfixed, i still support the theory of allergy cause stressful situations can disturb your immunity ,, thanks U

[FinalPanic]

I have to view the orgasm and the chemical mechanism that drives it as another unwanted stimulus to an exhausted system. Problem is it is part of me and not something I can walk away from like coffee or booze.

[fornicationDENIED2]

Poisers may have a sudden fall in dopamine after an orgasm...symptoms says.

Everyone gets a sudden decrease in dopamine thanks to the temporal increase in prolactin after ejaculation. When you really think about it, hyperprolactemia could in theory cause similar symptoms to POIS

Talking about prolactin, I managed to reduce it from 11.66 ng/mL to 4.03 ng/mL and I have experienced progress because  of this.I could say I am almost cured, there are still things I must do like updated thyroid bloodwork and see it that was fixed and some  insomnia  I get if I ejaculate at night which I can't explain yet, better than POIS but still...
 

[johanstefansson]

Do any of you guys here do adrenaline intensive stuff, like riding dirt bike or skydiving??

Could doing adrenaline intensive stuff maybe be the solution???

What do you think guys?

ps keep posting and help each other.

[johanstefansson]

I developed anxiety problems when about 19 whilst suffering terrible insomnia. This just made me feel so ill. Any stimulants - coffee, alcohol, cigarettes all had an amplified effect on me. I was ok before my sleeping troubles. Then my trouble started and BAM - all over the place.

I actually do think pois came first for you, then insomnia.

[demografx]

You're right!!

[LupeNL]

I'm convinced that POIS is one of many manifestations of mercury poisoning. Before you call me paranoid, give this a chance and make your own investigation.
 
I had POIS since I remember. Through my teens I had some other minor symptoms, but generally concidered myself healthy. We get slowly worse and don't recognize a problem until it's too late. I've been coming across the idea of mercury being a problem many times and always disregard it as a conspiracy theory.

Two years ago my health became terrible. Insomnia, terrible gut issues, candida, loss of weight, panic attacks. I felt like something attacked my nervous system. I thought I was dying. At that time I wished to go back to times when my biggest problem was POIS. Going through hell forced me to go deep looking for answers. 2 years of everyday investigation - reading forums, books, visiting doctors, medical tests, trying different paths, numerous supplements and analyzing reactions - all led me back to mercury.

Main reason why mercury poisoning is not recognized by western medicine, are the unique characteristics of this heavy metal:
1) It goes to your body much easier than leaves it - it can stay for years if not detoxed
2) It doesn't stay in blood, but go straight to tissues hence blood tests are useless
3) It has strong affinity with brain causing brain diseases and behavioral problems (google "Mad Hatter Disease")
4) Liver, gut and kidneys are many times affected as a major detox pathway
5) Even with high exposure symptoms don't show up immediately but gradually, sometimes after months
6) It's not about how much mercury you excrete (it show up in hair test or urine test) but how much you retain - people suffering are those who cannot excrete hence showing very little mercury in hair test but all other essential metals out of whack
7) There's no safe level of mercury - it's toxic in most elementar state
It's second most toxic metal on earth
9) Getting rid of mercury is a long process of chelation most likely taking 1-3 years
10) Mercury pass the placenta during pregnancy and acumulate in unborn baby

Major source of exposure:
-dental amalgam fillings (in your mother's mouth during pregnancy is enough)
-vaccines (mercury compound Thiomersal)
-seafood (tuna, shark, other big fishes)

For more info I recommend watching on youtube: dr Boyd Haley, dr David Geier, Minamata Disease, Acrodynia, Mercury Exposure channel, Trace Amounts trailer

After getting familiar with the topic I recommend reading Frequent Dose Chelation group where people were reporting problems after having orgasm as one among many symptoms of mercury toxicity

I'm far from being healthy today, but made big progress with supplement program slowly replenishing mineral deficiencies caused by mercury and bringing my body to balance. I started frequent dose chelation 6 months ago and it was a breakthrough for me. Redistribution symptoms which are part of the process, feel exactly the same as post orgasmic downfall which led me to believe that orgasm is connected with redistributing mercury in the body.

[vik1379]

I'm convinced that POIS is one of many manifestations of mercury poisoning.

I have gave a urine sample to determine the toxic metals. I have mercury levels in 26 times higher than normal in Germany. The doctor surprised me - said it was not a big defeat mercury, and it can not be the cause of "pois"

[LupeNL]

I'm not a doctor and I understand you have full trust in what your doctor told you...

I've been through hell, made my investigation and only thing I'm encouraging is to do the same. Think for yourself and think about all the symptoms you had in your life besides POIS. Even minor ones. You may be suprised with your findings. As was I....

If you're from Germany I recommend to watch on youtube: Detoxing Fundamentals - Klinghardt(1998)