[smart (OP)]

The soup of psychoactive chemicals in cannabis bind to a variety of endocannabinoid receptors in the brain, blood vessels, heart and gut.
This produces gross effects on brain activity which are visible in EEG patterns.
To me that sounds pretty impactful on intrinsic brain activity.

See: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234454/

Thanks for the link. Activation of endocannabinoid receptors (CB1, CB2) in the brain is a totally safe and natural method to neuromodulate stress. The definition of "intrinsic brain activity" is the biological mecanism of how the brain respond to stress. Antipsychotics alters intrinsic brain activity by normalizing dopamine and serotonin levels, which may increase oxidative stress. [1]

So it appears to me THC is very safe substance compared to atypical antipsychotics with selective affinities to dopamine D1 and D2 receptors..

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1) The ‘Holy Grail’ and ‘Poisoned Chalice’ Effects of Antipsychotics on Oxidative Stress in Schizophrenia: Can ‘Hormesis’ Explain this Paradox? http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361856/

[exothermic]

The definition of "intrinsic brain activity" is the biological mecanism of how the brain respond to stress.

Where did you find that definition?

Intrinsic brain activity refers to the state of functional & spontaneous connectivity in the resting state.

[smart (OP)]

The definition of "intrinsic brain activity" is the biological mecanism of how the brain respond to stress.

Where did you find that definition?

Intrinsic brain activity refers to the state of functional & spontaneous connectivity in to the resting state.

There's no such thing as the "resting state". The brain is continuously attacked by oxidative stress and must defend itself from lipid peroxidation. Things like atypical antipsychotics generates oxidative stress and inflammation. Marijuana use is a anti-inflammatory and a anti-oxidant.

[exothermic]

There's no such thing as the "resting state"

Consistent resting-state networks across healthy subjects

Functional MRI (fMRI) can be applied to study the functional connectivity of the human brain. It has been suggested that fluctuations in the blood oxygenation level-dependent (BOLD) signal during rest reflect the neuronal baseline activity of the brain, representing the state of the human brain in the absence of goal-directed neuronal action and external input, and that these slow fluctuations correspond to functionally relevant resting-state networks. Several studies on resting fMRI have been conducted, reporting an apparent similarity between the identified patterns. The spatial consistency of these resting patterns, however, has not yet been evaluated and quantified. In this study, we apply a data analysis approach called tensor probabilistic independent component analysis to resting-state fMRI data to find coherencies that are consistent across subjects and sessions. We characterize and quantify the consistency of these effects by using a bootstrapping approach, and we estimate the BOLD amplitude modulation as well as the voxel-wise cross-subject variation. The analysis found 10 patterns with potential functional relevance, consisting of regions known to be involved in motor function, visual processing, executive functioning, auditory processing, memory, and the so-called default-mode network, each with BOLD signal changes up to 3%. In general, areas with a high mean percentage BOLD signal are consistent and show the least variation around the mean. These findings show that the baseline activity of the brain is consistent across subjects exhibiting significant temporal dynamics, with percentage BOLD signal change comparable with the signal changes found in task-related experiments.

J. S. Damoiseaux, S. A. R. B. Rombouts, F. Barkhof,‖ P. Scheltens, C. J. Stam, S. M. Smith, and C. F. Beckmann
Proc Natl Acad Sci U S A. 2006 Sep 12; 103(37): 13848–13853.
Published online 2006 Aug 31. doi:  10.1073/pnas.0601417103
PMCID: PMC1564249
Neuroscience

[exothermic]

The brain is continuously attacked by oxidative stress and must defend itself from lipid peroxidation.

ROS are a part of normal cellular metabolism and defence systems. The body's antioxidant defense system can readily detoxify intracerebral ROS-mediated lipid peroxidation & cellular damage. It's over accumulation of ROS which alters this dynamic balance between the antioxidant system and ROS, eventually leading to cellular injury in the form of lipid peroxidation, protein oxidation & DNA damage.

[exothermic]

Things like atypical antipsychotics generates oxidative stress and inflammation.

To what degree?

[smart (OP)]

Things like atypical antipsychotics generates oxidative stress and inflammation.

To what degree?

Atypical antipsychotics appears to increases metabolic inflammation and obesity. I gained 10lbs since I'm forced to take this treatment, three years ago.

Fortunately, aripiprazole doesn't seem to induce oxidative stress: http://www.ncbi.nlm.nih.gov/pubmed/18367441

[exothermic]

Marijuana use is a anti-inflammatory and a anti-oxidant.

Indeed. Great stuff.

[smart (OP)]

My former psychiatrist is assuming the risk of cannabis-induced psychosis is too strong to withdraw from antipsychotics. Since my delusional thoughts includes seeing visible and persistent plume of aerosol dumped from military aircrafts in the stratosphere, I really doubt this "medication" is helpful for anything. At least smoking pot relieves me from the stress of having no power on this clandestine activity. However, I'm feeling lucky that Abilify doesn't cause major extrapyramidal symptoms, but I don't see how this drug could force me to agree in the official narrative, or deter me to research the clinical effects of chemtrails on human health. So far, my experience with Abilify is positive (the drug seem to promote neurogenesis). Thus, cannabis is great stuff and the combination with Abilify appears a good one, but I will never quit smoking pot if the reason is to ignore science and believe in pseudo-scientific voodoo.

[the5thforce]

It's very simple, all anti psychotics work to make a person tired because they're all tranquilizers, if that helps the person then yes anti-psychotics can treat symptoms caused by pathological alertness/wakefulness, they cannot cure hallucinations and they cannot change thoughts or opinions which are the root cause of dissonance, effective counselling is likely the best approach in all but the most hysterical individuals, problem is theres very few effective counselors and pharmaceuticals = big money


I'll also mention I've been diagnosed with nearly every major mental ailment known and i can confirm vocal hallucinations are very real and nearly impossible to distinguish from real voices, however, each time that ive gotten stuck in something like ocd, adhd, tourettes, pica, obesity, anorexia, sexual addiction, drug addiction, anxiety, depression, rage, manic euphoria, hallucinations, delusions, insomnia, I've gotten past it by researching the problem and practicing self discipline, I'm doing just fine so its very possible to adapt without the latest patented thousand dollar designer sleeping pill, but there's also times I do need a little help relaxing or falling asleep and while weed benzos alcohol and benadryl work better, anti psychotics can still get the job done

that being said i like to think the government is innocently/genuinely ignorant in their recklessness and if we're still breathing and riding the highs and lows in life were probably just as healthy as any other point in history. Ill also add that my current understanding of the vocal hallucinations is that my creator wanted me to gain something from their perspectives which i relentlessly take with a grain of salt, i believe we exist inside a simulation aka the matrix, and I'm linked up to the machine and being fed by the agents, but regardless of hallucinations everyone still makes their own decisions even if faced with the possibility of death.

If anyone reading this is struggling with vocal hallucinations the best thing you can do is not to fear them, avoid hostility, find common ground when necessary, be polite and eventually try to befriend them as much as possible without losing your sense of self or your morals