[smart (OP)]

Thimerosal is a dangerous mercury-based vaccine preservative and possibly a component of the universal flu vaccine. Vaccination doesn't protect much agaisn't recombinant flu virus because viral DNA always recombine itself.

[Bored chemist]

Thimerosal is a dangerous mercury-based vaccine preservative

No.
Stop there.
You are spreading lies.
https://en.wikipedia.org/wiki/Thiomersal_controversy

[smart (OP)]

Thimerosal is a dangerous mercury-based vaccine preservative

No.
Stop there.
You are spreading lies.
https://en.wikipedia.org/wiki/Thiomersal_controversy

No, I'm not. The deep biological effects of thimerosal exposure are well known.

See: http://www.sciencedirect.com/science/article/pii/S0009898115001023

[Bored chemist]

No, I'm not. The deep biological effects of thimerosal exposure are well known.

See: http://www.sciencedirect.com/science/article/pii/S0009898115001023

Did you read the bits that said that 6 out of 7 of the authors had a clear conflict of interest and the quote that says "
“It is important to note that concerns about the toxicity of Thiomersal are theoretical and that there is no compelling scientific evidence of a safety problem related to its use in vaccines, although public perception of risk has been reported in some countries.”

Well, lets have a brief though about the "toxicity" they raise.
The lowest concentration for which they report any effect is 1 nM and that was a chronic effect- not really relevant to an acute exposure like vaccination.
That's 1 nanomole per litre. For a 70 Kg human it means 70 nMoles
About 28 µ g of thiomersal
The more relevant studies- for longer term effects had concentrations 20 fold higher.
So, how much of the stuff do you get in a vaccination?
Well, - not enough to worry about.
about a tenth of that
http://www.vaccinesafety.edu/thi-table.htm

[smart (OP)]

Even a low-dose thimerosal exposure can cause serious neuronal injury.

[Bored chemist]

Even a low-dose thimerosal exposure can cause serious neuronal injury.

No It can't.
Even the data you posted shows that.
why make up lies?

[smart (OP)]

You speak nonsense.

Thimerosal is a neurotoxic mercury-based vaccine preservative which decrease TRPV1 activity and facilitate glutamate overflow.

https://www.ncbi.nlm.nih.gov/pubmed/15464274
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264864/

Who do you work for?

[Bored chemist]

Who do you work for?

Thanks for clarifying your paranoia.
It doesn't matter whom I work for.

Water is poisonous.
https://en.wikipedia.org/wiki/Water_intoxication
I suggest you avoid drinking it, or eating foods that contain it.

Alternatively, you might want to consider that the dose is also important.
That's why I did the rough calculations for you earlier.
You may remember that post of mine- it showed that there's not really a problem. Why are you still trying to claim that there is?

[smart (OP)]

Who do you work for?

Thanks for clarifying your paranoia.
It doesn't matter whom I work for.

Water is poisonous.
https://en.wikipedia.org/wiki/Water_intoxication
I suggest you avoid drinking it, or eating foods that contain it.

Alternatively, you might want to consider that the dose is also important.
That's why I did the rough calculations for you earlier.
You may remember that post of mine- it showed that there's not really a problem. Why are you still trying to claim that there is?

The dose is not really a problem for nontoxic agents, not mercury-based preservatives. Any doses of thimerosal can lead to unexpected consequences.

[Bored chemist]

Any doses of thimerosal can lead to unexpected consequences.

Do you understand the irony of saying that?

The dose is not really a problem for nontoxic agents, not mercury-based preservatives

Do you really not understand what a toxic dose is?

Lets face it, anyone reading this thread has now been well and truly informed that you have no idea what you are on about.

Since you know nothing bout thiomersal and toxicity, with luck they will realise that you probably know nothing about vaccines.

[smart (OP)]

How effective are flu vaccines?


1. Thimerosal is a mercury-based neurotoxin which regulate site-dependent IP3 receptors and alter TRPV1 activity via oxidative modulation of cysteine orthologs. The effect of thimerosal exposure may be an increased response of heat-sensitive TRPV1 receptors to low-frequency electromagnetic waves.

2. Flu vaccines are quite effective agents to trigger neurotoxic insults from the list of undisclosed components possibly included.

3. Flu vaccination is a experimental model to study how thimerosal additives can alter the psychological behavior by modulating TRPV1 receptors.

[Bored chemist]

How effective are flu vaccines?


1. Thimerosal is a mercury-based neurotoxin which regulate site-dependent IP3 receptors and alter TRPV1 activity via oxidative modulation of cysteine orthologs. The effect of thimerosal exposure may be an increased response of heat-sensitive TRPV1 receptors to low-frequency electromagnetic waves.

2. Flu vaccines are quite effective agents to trigger neurotoxic insults from the list of undisclosed components possibly included.

3. Flu vaccination is a experimental model to study how thimerosal additives can alter the psychological behavior by modulating TRPV1 receptors.

I have added the bits you miseed out

1. Thimerosal is a mercury-based neurotoxin which regulate site-dependent IP3 receptors and alter TRPV1 activity via oxidative modulation of cysteine orthologs. The effect of thimerosal exposure may be an increased response of heat-sensitive TRPV1 receptors to low-frequency electromagnetic waves.
But only at concentrations much higher that people are exposed to when getting flu jabs, so this toxicity is not clinically relevant- it's just a scare story.

"Flu vaccines are quite effective agents to trigger neurotoxic insults from the list of undisclosed components possibly included."
This is Tkadm30 announcing to the world that he thinks there's a "list of undisclosed components".
Well, if they aren't disclosed, how are they listed.
However the reality is that many people have had flu  vaccines. Occasionally, they have reactions to it. More often than not it just protects them from flu.
On the whole the risks from the vaccine are smaller than those from the risk of flu.
They are certainly not " quite effective agents to trigger neurotoxic insults " because we would have noticed.

"Flu vaccination is a experimental model to study how thimerosal additives can alter the psychological behavior by modulating TRPV1 receptors."
No, it's not. It's not experimental- it's practical healthcare.
If it was an experiment they would do it differently.
For example, flu jabs are usually given to the elderly but not the young.
If there was a change in behaviour it would be impossible to tell if it was due to age or to the jabs.

Scientists are cleverer than that: Tkadm30 isn't

It would help this thread if the stuff about mercury was moved to another thread.

[smart (OP)]

If we let Bored chemist hijack my warnings about the safety of flu vaccines, nobody will dare to expose the real biological effects of this nonsense medical hoax. I propose we rename this thread "Do thimerosal damage the central nervous system?"

[smart (OP)]

https://www.fda.gov/BiologicsBloodVaccines/SafetyAvailability/VaccineSafety/UCM096228#pres

At concentrations found in vaccines, thimerosal meets the requirements for a preservative as set forth by the United States Pharmacopeia; that is, it kills the specified challenge organisms and is able to prevent the growth of the challenge fungi (U.S. Pharmacopeia 2004). Thimerosal in concentrations of 0.001% (1 part in 100,000) to 0.01% (1 part in 10,000) has been shown to be effective in clearing a broad spectrum of pathogens. A vaccine containing 0.01% thimerosal as a preservative contains 50 micrograms of thimerosal per 0.5 mL dose or approximately 25 micrograms of mercury per 0.5 mL dose. For comparison, this is roughly the same amount of elemental mercury contained in a 3 ounce can of tuna fish.

50 micrograms of thimerosal per 0.5 mL is enough elemental mercury to alter the dopaminergic system. See: https://www.ncbi.nlm.nih.gov/pubmed/21549155 

[smart (OP)]

I updated the title.

It appears the effects of thimerosal (THIM) on the dopaminergic system are poorly understood. I propose that thimerosal may act as a selective dopamine inhibitor. See: https://www.ncbi.nlm.nih.gov/pubmed/21549155

In specific, the loss of dopamine density is evidence of THIM-mediated interactions with dopamine neurons in the striatum.

[Bored chemist]

I updated the title.

And I will answer it.
"Do thiomerosal (thimerosal) damage the central nervous system?"
No- at least, not at doses you get in vaccines.

OK, you can stop now.

[smart (OP)]

50 micrograms of thimerosal per 0.5 mL is enough elemental mercury to alter the dopaminergic system. See: https://www.ncbi.nlm.nih.gov/pubmed/21549155 

You can stop the vaccination advocacy please.

[smart (OP)]

Here's another one:

Biol Trace Elem Res. 2015 Feb;163(1-2):28-38. doi: 10.1007/s12011-014-0169-3. Epub 2014 Nov 11.
A case-control study evaluating the relationship between thimerosal-containing haemophilus influenzae type b vaccine administration and the risk for a pervasive developmental disorder diagnosis in the United States.


Routine childhood vaccination is an important public health tool to reduce the morbidity and mortality associated with infectious diseases, but the present study provides new epidemiological evidence of a significant relationship between increasing organic Hg exposure from Thimerosal-containing vaccines and the subsequent risk of PDD diagnosis in males and females.

https://www.ncbi.nlm.nih.gov/pubmed/25382662

[Bored chemist]

50 micrograms of thimerosal per 0.5 mL is enough elemental mercury to alter the dopaminergic system. See: https://www.ncbi.nlm.nih.gov/pubmed/21549155 

You can stop the vaccination advocacy please.

OK, I had a look at that page and it says "Here we investigated neonatal treatment with THIM (at doses 12, 240, 1440 and 3000 μg Hg/kg) "

50 µg of mercury (the amount in a vaccination) would, in a typical 3.5 kg infant give rise to a dose of 50/3.5 i.e. 14.3 migrograms per kilo.
So, almost all the "experiments" were done at unrealistic doses.

They clearly tested at 200 times the realistic dose for a reason.
I postulate that the reason they used an absurdly high dose was that they knew that the right dose wouldn't have a noticeable effect.

Why do you think  they chose to use such a silly dose regimen?

And, no, I will not stop advocating things that save millions of lives.
https://www.unicef.org/pon96/hevaccin.htm

Why do you think I should?

[Kryptid]

https://www.fda.gov/BiologicsBloodVaccines/SafetyAvailability/VaccineSafety/UCM096228#pres

At concentrations found in vaccines, thimerosal meets the requirements for a preservative as set forth by the United States Pharmacopeia; that is, it kills the specified challenge organisms and is able to prevent the growth of the challenge fungi (U.S. Pharmacopeia 2004). Thimerosal in concentrations of 0.001% (1 part in 100,000) to 0.01% (1 part in 10,000) has been shown to be effective in clearing a broad spectrum of pathogens. A vaccine containing 0.01% thimerosal as a preservative contains 50 micrograms of thimerosal per 0.5 mL dose or approximately 25 micrograms of mercury per 0.5 mL dose. For comparison, this is roughly the same amount of elemental mercury contained in a 3 ounce can of tuna fish.

50 micrograms of thimerosal per 0.5 mL is enough elemental mercury to alter the dopaminergic system. See: https://www.ncbi.nlm.nih.gov/pubmed/21549155 

For the record, a pure element and a compound containing the element will not have the same toxicity. Table salt contains chlorine but is nowhere near as toxic as chlorine gas.