[katieHaylor (OP)]

Barrie wants to know:

What has been learned about the use of plasma donations that contain Covid-19 antibodies as a treatment for infected patients? China have used this treatment and they must have learned how effective it is. What are UK and other people's hospital findings?

What do you think?

[Zer0]

Hello Barrie!
🙋
Sorry for the Delay.
🙏

" The Department of Health and Social Care has asked NHS Blood and Transplant to stop collecting convalescent plasma donations. "

" This follows the completed analysis of trial results which showed no overall benefit for people in hospital with coronavirus and a decision not to proceed with a third trial into plasma use early in the disease. "

https://www.nhsbt.nhs.uk/covid-19-research/plasma-programme/




P.S. - I had also Read somewhere that WHO dropped CPT from possible treatment options list.
But Unable to Verify the information on the WHO webpage.
👎
(Note* - As Covid19 is New, data keeps coming in on an hourly basis...New techniques & methods are adopted & modified constantly.
TNS does Not make any Recommendations.
Please Contact your Family Doctor/Physician for stable valid medical advice. )
🖖

[CliffordK]

I believe there is some benefit from the monoclonal antibody treatment, especially when started early. 

Since one is fighting both the impact of the virus as well as the impact of the immune system, one would expect the antibody treatments to help knock down the virus when it is still spreading within the body, but not particularly to help clear the lungs as the disease progresses.

[evan_au]

Another approach that has proved helpful in other outbreaks is "ring-fence vaccination".
- It takes a couple of weeks after vaccination to mount a good immune response
- But a partial immune response starts after a day or so, which would limit the severity of the disease in newly-infected individuals

So if you discover an infected person, you immediately vaccinate everyone who might have contact with that person
- and anyone that they might have come in contact with...

This starts a stronger and more targeted response to infection amongst those who have been exposed, but are not showing symptoms
- And prevents the infected people from passing it on to others.

Not so effective in those who are already showing symptoms
- But then, neither was convalescent plasma...
 
See: https://en.wikipedia.org/wiki/Ring_vaccination

[CliffordK]

Another approach that has proved helpful in other outbreaks is "ring-fence vaccination".

Somewhat like what we do with Rabies post exposure, pre symptomatic.

Data is a bit ambiguous, but the J&J vaccine seems to have one of the strongest and most rapid early responses.