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  4. What is safety conditioning?
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What is safety conditioning?

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Offline smart (OP)

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What is safety conditioning?
« on: 11/04/2021 23:33:24 »
Hi all,

Compulsory mask wearing is a subliminal method to stimulate stress-mediated dopamine transmission in the striatum thereby enhancing post-synaptic D2 receptors connectivity from the central amygdala and nucleus accumbens. This extracellular dopamine activity in the striatum may prime neuronal (chemo)signaling associated to active avoidance conditioning, a Pavlovian type of instrumental learning.

Consequently, is dopamine-mediated avoidance conditioning a reversible fear-extinction learning paradigm?

What do you think?

smart
« Last Edit: 11/04/2021 23:49:47 by smart »
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Offline Origin

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Re: What is safety conditioning?
« Reply #1 on: 12/04/2021 00:09:20 »
I think you are joking...
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Offline smart (OP)

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Re: What is safety conditioning?
« Reply #2 on: 12/04/2021 07:02:07 »
Quote from: Origin on 12/04/2021 00:09:20
I think you are joking...

lol...  :D

Thanks for sharing!
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Offline Kryptid

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Re: What is safety conditioning?
« Reply #3 on: 12/04/2021 07:31:51 »
Compulsory mask-wearing is to reduce the spread of COViD. There's nothing subliminal involved.
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Offline smart (OP)

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Re: What is safety conditioning?
« Reply #4 on: 12/04/2021 07:47:45 »
Quote from: Kryptid on 12/04/2021 07:31:51
Compulsory mask-wearing is to reduce the spread of COViD. There's nothing subliminal involved.

A great amount of documentation is fully available on the effects of intermittent hypoxic stress on neuronal activity, arousal and human metabolism. Safety conditioning (Active avoidance) is just another paradigm associated to the psychological outcomes of chronic surgical mask wearing.

I believe a subliminal (or passive) outcome associated with chronic mask wearing is in the avoidance paradigm as there is nothing in COVID19 theory that may suggest a direct threat cue, thereby this compulsory behavior could be the result of instrumental (fear) conditioning.


Anyway, your typical avoidance of the initial question is largely insufficient to surprise me. ;)
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Offline Kryptid

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Re: What is safety conditioning?
« Reply #5 on: 12/04/2021 07:52:37 »
I wear a mask for hours while doing physical labor at work. I don't experience hypoxic stress from it, so I don't know why you are bringing that up.
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Offline smart (OP)

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Re: What is safety conditioning?
« Reply #6 on: 12/04/2021 08:12:18 »
Quote from: Kryptid on 12/04/2021 07:52:37
I wear a mask for hours while doing physical labor at work. I don't experience hypoxic stress from it, so I don't know why you are bringing that up.

I guess you never considered the fact that many healthcare workers do suffers from mild/intermittent hypoxic stress associated with chronic surgical mask wearing at work... These acute physiological effects are well known among scientists working on human metabolism and hypoxia. 

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Offline Bored chemist

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Re: What is safety conditioning?
« Reply #7 on: 12/04/2021 08:35:05 »
Quote from: smart on 12/04/2021 07:47:45
A great amount of documentation is fully available on the effects of intermittent hypoxic stress
And because masks do not produce hypoxia, that research is irrelevant, isn't it?


If you think this

Quote from: smart on 12/04/2021 08:12:18
many healthcare workers do suffers from mild/intermittent hypoxic stress

 is true then you need to show evidence.

Because, in the real world, the facts show that they do not.


https://www.mirror.co.uk/news/uk-news/nhs-doctor-begs-people-wear-22366171
https://abcnews.go.com/GMA/Wellness/doctor-runs-22-miles-face-mask-prove-impair/story?id=72353323

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Offline smart (OP)

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Re: What is safety conditioning?
« Reply #8 on: 12/04/2021 08:47:49 »
Quote from: Bored chemist on 12/04/2021 08:35:05
Quote from: smart on 12/04/2021 07:47:45
A great amount of documentation is fully available on the effects of intermittent hypoxic stress
And because masks do not produce hypoxia, that research is irrelevant, isn't it?


If you think this

Quote from: smart on 12/04/2021 08:12:18
many healthcare workers do suffers from mild/intermittent hypoxic stress

 is true then you need to show evidence.

Because, in the real world, the facts show that they do not.


https://www.mirror.co.uk/news/uk-news/nhs-doctor-begs-people-wear-22366171
https://abcnews.go.com/GMA/Wellness/doctor-runs-22-miles-face-mask-prove-impair/story?id=72353323



This wishful thinking is not appropriate scientific discussion as its not relevant to discuss hypoxia-related topics in this thread.

In contrast, chronic/intermittent mask wearing do obviously alter normoxic oxygenation levels (ie: SpO2/PAO2) but this is out of scope and COVID19-related misinformation is not helpful here.

Please help yourself and go read some online books.

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Offline Bored chemist

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Re: What is safety conditioning?
« Reply #9 on: 12/04/2021 10:38:41 »
Quote from: smart on 12/04/2021 08:47:49
This wishful thinking is not appropriate scientific discussion
Then stop doing it.
Do what the rest of us do, and use actual evidence (rather than silly conspiracies) as the basis for your decisions.

Quote from: smart on 12/04/2021 08:47:49
its not relevant to discuss hypoxia-related topics in this thread.
Well, if it's not relevant, why did you bring it up by posting this?

Quote from: smart on 12/04/2021 07:47:45
the effects of intermittent hypoxic stress on neuronal activity,


Quote from: smart on 12/04/2021 08:47:49
In contrast, chronic/intermittent mask wearing do obviously alter normoxic oxygenation levels (ie: SpO2/PAO2)
That is clearly wrong- and the videos prove it.
Quote from: smart on 12/04/2021 08:47:49
and COVID19-related misinformation is not helpful here.
Then stop posting it.
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Offline Bored chemist

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Re: What is safety conditioning?
« Reply #10 on: 12/04/2021 10:39:29 »
Quote from: Bored chemist on 12/04/2021 08:35:05
If you think this

Quote from: smart on Today at 08:12:18
"many healthcare workers do suffers from mild/intermittent hypoxic stress"

 is true, then you need to show evidence.
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Offline evan_au

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Re: What is safety conditioning?
« Reply #11 on: 12/04/2021 11:21:07 »
Quote from: smart
there is nothing in COVID19 theory that may suggest a direct threat
When China started two 1000-bed hospitals in Wuhan (for completion in 2 weeks), that suggested a direct threat to me.
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Offline Origin

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Re: What is safety conditioning?
« Reply #12 on: 12/04/2021 13:32:53 »
Quote from: smart on 12/04/2021 07:02:07
lol... 

Thanks for sharing!
You weren't joking?!
You really believe that mask wearing is some sort of conspiracy?  OK then, have a good day and don't forget to wear your tin foil hat.
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Offline Bored chemist

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Re: What is safety conditioning?
« Reply #13 on: 12/04/2021 13:36:17 »
Quote from: smart on 12/04/2021 07:47:45
there is nothing in COVID19 theory that may suggest a direct threat cue
I don't know about the "theory", but in practice:
Deaths:
2,951,714
from
https://www.worldometers.info/coronavirus/
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Offline Kryptid

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Re: What is safety conditioning?
« Reply #14 on: 12/04/2021 14:58:14 »
Quote from: smart on 12/04/2021 08:47:49
In contrast, chronic/intermittent mask wearing do obviously alter normoxic oxygenation levels

If it's "obvious", then you should be able to supply evidence showing that it is so.
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Offline smart (OP)

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Re: What is safety conditioning?
« Reply #15 on: 14/04/2021 21:48:51 »
Quote from: Kryptid on 12/04/2021 14:58:14
Quote from: smart on 12/04/2021 08:47:49
In contrast, chronic/intermittent mask wearing do obviously alter normoxic oxygenation levels

If it's "obvious", then you should be able to supply evidence showing that it is so.

That is not the subject of this thread. I was hoping to discuss about the relevant association between chronic mask wearing and avoidance learning. In contrast, there is sufficient peer-reviewed studies on the effects of mask wearing on oxygen and carbon dioxide consumption. There was no need to hijack this post with a low-level brainwashing video.... :(

Predator avoidance conditioning is a real problem associated to the etiology of dysfunctional surgical mask use and very few people are aware of the psychological effects associated to long-term mask wearing.

Anyway, my research found reliable evidences that stress-dependent cortisol overexpression may mediates avoidance response conditioning in people wearing a face mask on long-term basis by stimulating inhibitory dopamine signaling in the striatum, thereby promoting avoidance behavior, a lesser-known type of instrumental/safety conditioning.

Likewise, hypoxic stress may drives dopaminergic signaling thereby enhancing instrumental conditioning of avoidance behavior: https://www.sciencedirect.com/science/article/pii/S1074742711000931

smart

ps: please stop the low-level ad hominem thread hijacking  8)
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Offline Kryptid

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Re: What is safety conditioning?
« Reply #16 on: 14/04/2021 21:54:09 »
Quote from: smart on 14/04/2021 21:48:51
That is not the subject of this thread.

Masks producing hypoxia is a necessary component of your idea, is it not? If masks don't produce hypoxia, then your idea is wrong.

Quote from: smart on 14/04/2021 21:48:51
In contrast, there is sufficient peer-reviewed studies on the effects of mask wearing on oxygen and carbon dioxide consumption.

Care to post them?

Quote from: smart on 14/04/2021 21:48:51
There was no need to hijack this post with a low-level brainwashing video....

How are those videos brain washing?

Quote from: smart on 14/04/2021 21:48:51
Anyway, my research found reliable evidences

Then please post that evidence.

Quote from: smart on 14/04/2021 21:48:51
Likewise, hypoxic stress may drives dopaminergic signaling thereby enhancing instrumental conditioning of avoidance behavior: https://www.sciencedirect.com/science/article/pii/S1074742711000931

Which is irrelevant if masks don't cause hypoxia.

Quote from: smart on 14/04/2021 21:48:51
ps: please stop the low-level ad hominem thread hijacking 

I never used ad hominem.
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Offline smart (OP)

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Re: What is safety conditioning?
« Reply #17 on: 14/04/2021 22:03:45 »
Quote from: Kryptid on 14/04/2021 21:54:09
Quote from: smart on 14/04/2021 21:48:51
That is not the subject of this thread.

Masks producing hypoxia is a necessary component of your idea, is it not? If masks don't produce hypoxia, then your idea is wrong.

Quote from: smart on 14/04/2021 21:48:51
In contrast, there is sufficient peer-reviewed studies on the effects of mask wearing on oxygen and carbon dioxide consumption.

Care to post them?

Quote from: smart on 14/04/2021 21:48:51
There was no need to hijack this post with a low-level brainwashing video....

How are those videos brain washing?

Quote from: smart on 14/04/2021 21:48:51
Anyway, my research found reliable evidences

Then please post that evidence.

Quote from: smart on 14/04/2021 21:48:51
Likewise, hypoxic stress may drives dopaminergic signaling thereby enhancing instrumental conditioning of avoidance behavior: https://www.sciencedirect.com/science/article/pii/S1074742711000931

Which is irrelevant if masks don't cause hypoxia.

Quote from: smart on 14/04/2021 21:48:51
ps: please stop the low-level ad hominem thread hijacking 

I never used ad hominem.

Did you ever attempted to hold your breath while underwater? Chronic/intermittent mask wearing does alter systemic oxygen and CO2 input in such ways that your brain cannot notice any differences. This is known as hypobaric hypoxia and its well-known scientific phenomenon.  ;)

Anyway, if you insist on discussing about chronic hypoxia here i should probably mute you off, since thread hijacking is definitely not my cup of tea.. . 



« Last Edit: 14/04/2021 22:05:52 by smart »
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Offline Kryptid

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Re: What is safety conditioning?
« Reply #18 on: 14/04/2021 22:07:47 »
Quote from: smart on 14/04/2021 22:03:45
Did you ever attempted to hold your breath while underwater ?

Normally, you wouldn't be expected to hold your breath while wearing a mask.

Quote from: smart on 14/04/2021 22:03:45
chronic/intermittent mask wearing does alter systemic oxygen and CO2 input in such ways that your brain cannot notice any differences. This is known as hypobaric hypoxia and its well-known scientific phenomenon.

Evidence please.

Quote from: smart on 14/04/2021 22:03:45
Anyway, if you insist on discussing about chronic hypoxia here

Please explain to me how your idea does not involve chronic hypoxia.

Quote from: smart on 14/04/2021 22:03:45
i should probably mute you off

Good luck, since I'm a moderator.

Quote from: smart on 14/04/2021 22:03:45
since thread hijacking is definitely not my cup of tea.

This isn't thread hijacking. If you will recall what you said here:

Quote from: smart on 12/04/2021 07:47:45
A great amount of documentation is fully available on the effects of intermittent hypoxic stress on neuronal activity, arousal and human metabolism. Safety conditioning (Active avoidance) is just another paradigm associated to the psychological outcomes of chronic surgical mask wearing.

You are definitely talking about mask-induced hypoxia.
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Offline Bored chemist

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Re: What is safety conditioning?
« Reply #19 on: 14/04/2021 22:31:41 »
Quote from: smart on 14/04/2021 22:03:45
hypobaric hypoxia
What is hypobaric about it?
Or are you just stitching "sciencey sounding words" together?
Quote from: smart on 14/04/2021 22:03:45
Chronic/intermittent mask wearing does alter systemic oxygen and CO2 i
The evidence makes it clear that your claim is false.

Quote from: smart on 14/04/2021 21:48:51
Anyway, my research found reliable evidences
Cite it , or shut it.
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