[smart (OP)]

hypobaric hypoxia

What is hypobaric about it?
Or are you just stitching "sciencey sounding words" together?

Chronic/intermittent mask wearing does alter systemic oxygen and CO2 i

The evidence makes it clear that your claim is false.

Anyway, my research found reliable evidences

Cite it , or shut it.

You and Kryptid are deceitfully short-minded, perhaps because it goes inline with the policies on this forum. I have no motivations in trying to discuss science with people not able to understand that 2+2=4 or that simply blocking your nose and mouth do affect breathing. There is basic science manuals for this online and elsewhere.

Moreover its very unfortunate that this forum is being condemned to such evil deceptive thread hijackings by people that try to convince me that 2+2=5.

smart

[Kryptid]

that simply blocking your nose and mouth do affect breathing.

Except that the kind of masks encouraged during the pandemic are not "blocking" your nose and mouth. They are porous. They allow gases in and out.

Moreover its very unfortunate that this forum is being condemned to such evil deceptive thread hijackings by people that try to convince me that 2+2=5.

Please show where such a thing happened.

[smart (OP)]

that simply blocking your nose and mouth do affect breathing.

Except that the kind of masks encouraged during the pandemic are not "blocking" your nose and mouth. They are porous. They allow gases in and out.

Yes they do allow O2 and CO2 exchanges except they also alter the respiratory rate accordingly. OT.

[Colin2B]

Moreover its very unfortunate that this forum is being condemned

Please show evidence of anyone condemning this forum for questioning your claims - other than yourself.

[Kryptid]

Yes they do allow O2 and CO2 exchanges except they also alter the respiratory rate accordingly.

First of all, evidence?

Second of all, can you show how an elevated respiratory rate would somehow lead to hypoxia?

[Petrochemicals]

Masks of the variety demonstrated above don't work either way. They may stop you sneezing a large droplet onto an open wound in an operation theatre but won't stop you inhaling soot, operating theatres have ventilation to deal with airborne particles. I thought the fact that cases rose even though mask wearing was mandatory proved that. Plus the fact dear old Sweden failed to implode even without a lockdown.

[Kryptid]

I thought the fact that cases rose even though mask wearing was mandatory proved that.

No, because (1) masks are not 100% effective, (2) those who do wear masks don't wear them 24/7, and (3) there are plenty of those who either don't wear their masks properly or don't wear them at all.

[Bored chemist]

hypobaric hypoxia

What is hypobaric about it?
Or are you just stitching "sciencey sounding words" together?

Chronic/intermittent mask wearing does alter systemic oxygen and CO2 i

The evidence makes it clear that your claim is false.

Anyway, my research found reliable evidences

Cite it , or shut it.

You and Kryptid are deceitfully short-minded, perhaps because it goes inline with the policies on this forum. I have no motivations in trying to discuss science with people not able to understand that 2+2=4 or that simply blocking your nose and mouth do affect breathing. There is basic science manuals for this online and elsewhere.

Moreover its very unfortunate that this forum is being condemned to such evil deceptive thread hijackings by people that try to convince me that 2+2=5.

smart

Why didn't you simply cite the evidence you claim to have found?
That would have left Kryptid and me looking really stupid and you looking like a scientists.
Your decision not to cite it achieved the opposite.

[smart (OP)]

This post contains False News and a bogus study.
Please read https://www.factcheck.org/2021/04/scicheck-stories-falsely-cite-stanford-study-to-misinform-on-face-masks/ before deciding whether to read the post

WARNING - THIS POST IS FALSE NEWS - CLICK AND BE BRAINWASHED AT YOUR OWN RISK

Spoiler: show

 [/b]

From "Facemasks in the COVID-19 era: A health hypothesis": https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680614/

Physiological effects of wearing facemasks

Wearing facemask mechanically restricts breathing by increasing the resistance of air movement during both inhalation and exhalation process [12], [13]. Although, intermittent (several times a week) and repetitive (10–15 breaths for 2–4 sets) increase in respiration resistance may be adaptive for strengthening respiratory muscles [33], [34], prolonged and continues effect of wearing facemask is maladaptive and could be detrimental for health [11], [12], [13]. In normal conditions at the sea level, air contains 20.93% O2 and 0.03% CO2, providing partial pressures of 100 mmHg and 40 mmHg for these gases in the arterial blood, respectively. These gas concentrations significantly altered when breathing occurs through facemask. A trapped air remaining between the mouth, nose and the facemask is rebreathed repeatedly in and out of the body, containing low O2 and high CO2 concentrations, causing hypoxemia and hypercapnia [35], [36], [11], [12], [13]. Severe hypoxemia may also provoke cardiopulmonary and neurological complications and is considered an important clinical sign in cardiopulmonary medicine [37], [38], [39], [40], [41], [42]. Low oxygen content in the arterial blood can cause myocardial ischemia, serious arrhythmias, right or left ventricular dysfunction, dizziness, hypotension, syncope and pulmonary hypertension [43]. Chronic low-grade hypoxemia and hypercapnia as result of using facemask can cause exacerbation of existing cardiopulmonary, metabolic, vascular and neurological conditions [37], [38], [39], [40], [41], [42].

Notice im not posting a random low-level video link to provide real evidences. 

smart

[smart (OP)]

For people interested in stress-induced avoidance conditioning a separate thread about this topic is available here: <<<link removed>>>

[Kryptid]

Well, how about that? You actually did find something that supports your claim. To an extent, at least. It seems that chronic mask wearing can indeed reduce oxygen levels and increase carbon dioxide levels in the blood. The question now is, is it at a level that is enough to be concerned about? That doesn't appear to be completely clear, as this points out: https://clinicaltrials.gov/ct2/show/NCT04670484

There is some evidence that the use of surgical masks can induce mild hypoxia with a low level of activity (e.g. performing surgery) with prolonged use. There is no evidence that this decrease in oxygenation is clinically significant. The degree of hypoxia associated with surgical mask use, N-95 mask use, or the combination at rest and with exertion is unclear and warrants further investigation, particularly given the current widespread use of both due to the COVID-19 pandemic. Our working hypothesis is that there is a decrement in oxygenation with the use of a mask with exertion. The general public is being advised to wear a mask, including those with pre-existing pulmonary disease and heart disease. If there is evidence of a statistically significant decrease in oxygen saturation with short duration mask use with exertion, then further studies on patients at risk for decompensation due to mask-induced hypoxia is warranted. Our working hypothesis is that there is a decrement in oxygenation with the use of a mask with exertion.

Whether or not it is significant probably depends on the individual as well. Then there is also this: https://www.mayoclinichealthsystem.org/hometown-health/speaking-of-health/debunked-myths-about-face-masks

3. Myth: Wearing a mask will increase the amount of carbon dioxide I breathe and will make me sick.
For many years, health care providers have worn masks for extended periods of time with no adverse health reactions. The CDC recommends wearing cloth masks while in public, and this option is very breathable. There is no risk of hypoxia, which is lower oxygen levels, in healthy adults. Carbon dioxide will freely diffuse through your mask as you breathe.

[smart (OP)]

3. Myth: Wearing a mask will increase the amount of carbon dioxide I breathe and will make me sick.

Fact check: Breathing through a face respirator or surgical mask will decrease oxygen and carbon dioxide consumption.

Note that this is out of scope from the original thread.

[Kryptid]

Fact check: Breathing through a face respirator or surgical mask will decrease oxygen and carbon dioxide consumption.

Well, you don't consume carbon dioxide, so that says a lot about that "fact check" of yours...

Note that this is out of scope from the original thread.

Okay, if you don't want to talk about hypoxia, I'll take a look at your original question:

Consequently, is dopamine-mediated avoidance conditioning a reversible fear-extinction learning paradigm?

If your question is whether people will willingly stop wearing masks once the pandemic is over, the answer is obviously yes. I take my mask off whenever I get home.

[Bored chemist]

For people interested in stress-induced avoidance conditioning a separate thread about this topic is available here: <<<link removed>>>

In a forum which, under the heading of "Biology and Medicine" includes just three sub headings
Sexology
Synthetic biology and
neurocardiology.

That's an interesting level of specialisation.

And which also says "115 Posts in 51 Topics by 2 Members. "
Basically, you wrote a forum to agree with yourself.

Do you have any idea how pathetic that is?

[smart (OP)]

Well, you don't consume carbon dioxide, so that says a lot about that "fact check" of yours...

Thats incorrect. Even without rebreathing through a surgical mask a small percentage of CO2 will get inhaled.

If your question is whether people will willingly stop wearing masks once the pandemic is over, the answer is obviously yes. I take my mask off whenever I get home.

Thank you for your input.

I recall to had many interesting talks with you back in the days.

I noticed as well that many people are dreaming that this pandemic scam will end someday.

Just for your info i don't wear mask outside except when mandatory in local stores. I believe this type of stress-dependent conditioning do promotes pathological social avoidance as excessive (hypoxic) stress does stimulate inhibitory dopamine activity in the ventral striatum.

Likewise, striatal dopamine signaling can also prime the amygdala and hippocampus towards instrumental learning of avoidance.

In other words, the hypoxia-mediated overstimulation of dopaminergic cells in the striatum may potentially act as partial/selective dopamine agonists thereby promoting antipsychotic activity.

Unfortunately, that novel mechanisms is poorly understood and most people don't understand science enough to notice any subliminal changes in their behavior since the beginning of the "pandemic".

smart

[Colin2B]

I noticed as well that many people are dreaming that this pandemic scam will end someday.

Please steer well clear of any conspiracy theories. This pandemic is real.
Also, please do not advertise your personal forum created to support your theories.

[Kryptid]

Thats incorrect. Even without rebreathing through a surgical mask a small percentage of CO2 will get inhaled.

Yes, but you don't "consume" it like you consume oxygen. It's a waste product, not a vital gas. Besides, following your logic, shouldn't the face mask increase carbon dioxide consumption instead of decreasing it?

pandemic scam

It isn't a scam. The virus is real. I know a lot of people who caught it and one who died from it.

In other words, the hypoxia-mediated

So now you've brought up hypoxia again. Is hypoxia relevant to this thread or not? Make up your mind.

[Bored chemist]

I believe this type of stress-dependent conditioning do promotes...

We recognise that you believe it.
But we keep asking for your evidence in support of that belief and you don't provide any.

In effect, you are preaching.

[smart (OP)]

Yes, but you don't "consume" it like you consume oxygen. It's a waste product, not a vital gas. Besides, following your logic, shouldn't the face mask increase carbon dioxide consumption instead of decreasing it?

i believe both O2 and CO2 are essential particles that are being inhaled during normal respiration.

Correct me if im wrong.

smart

[Kryptid]

i believe both O2 and CO2 are essential particles that are being inhaled during normal respiration.

Oxygen is, but carbon dioxide is not. Carbon dioxide is a waste product of respiration and the air is normally less than 1% carbon dioxide (compared to about 21% oxygen).