Post Orgasmic Illness Syndrome (POIS)

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1600 on: 15/10/2008 00:36:54 »
JUST TO LET YOU ALL KNOW:  I emailed and requested the recovered ex-POIS forum member to post his story on the
site. He sounds like he might be willing to do that some time. He is very informed on hormonal issues, so I hope he does.

Great, girlwind! I also emailed a dozen or so early forum members who posted, inviting them back (just to tune in, not to necessarily post like you suggested, which was terrific). Hope they do come back. Or maybe they've been back and are just quiet.
« Last Edit: 15/10/2008 05:16:36 by demografx »

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1601 on: 15/10/2008 01:07:45 »
Here is the site of Dr. Louis Ignarro, Professor of Molecular Biology at UCLA. He won a nobel prize for his research in NO as it relates to heart disease prevention. Theres are some videos in which he explains NO.

http://www.drignarro.com/about.php

This supplement was made in consultation with him, it's a bit pricey but perhaps it's good.

http://www.amazon.com/Herbalife-Niteworks/dp/B0009XFJ40


Another NO supplement that sounds interesting:

http://www.amazon.com/Oxegen-Stimulator-Vasodilator-Dietary-Supplement/dp/B000E9V6IW


John, great sleuthing!

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Offline Finally

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1602 on: 15/10/2008 05:34:23 »
SOME OBSERVATIONS:

After my last orgasm (saturday)I immediately took some sea salt and used ice packs to cool off the fever areas shoulder, neck, face and one down my pants.
I woke Sunday a little tired but not feeling too bad.  libido was back to full strength.  My muscles have been feeling  a little stiff  the last few days but getting better.
Sea salt does contain a lot of iodine.  I am slowly beginning to try Dhea although the lab tests showed it normal.  I have started at 10 mg/day.  It is rough to take on an empty stomach though.

I took Argenine at one time.  It gave me harder, fuller erections but I didn't notice any Pois benefit.  In fact I think I had more muscle stiffness.  I started getting similar symptoms from alcohol so I gave that up.  POIs is somewhat similar to a hangover. I don't know how much of a connection there is. 

Also If I have an injury sex prolongs the time it takes to heal

I take a suplement with Caffeine and Phenylalinine in the Am or 2x day with fruit juice.  It helps mood and with energy.  Also Enzymes(Bromeline, protease) and a probiotic.

The mountain success story was interesting as I seemed to have less symptoms with higher elevation and thinner air.
 

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Offline martin88

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1603 on: 15/10/2008 13:18:24 »
Hi Finally,
I'd like to know the quantity of salt you take, and is it iodized salt ?

I heard about L-citrulline in the video of the scientist who's talking about nitric oxyde, but i wasn't able to understand (english deficiency), i was hearing sertraline ... We can find this in watermelon. 
http://www.webmd.com/erectile-dysfunction/news/20080701/watermelon-a-natural-viagra
On a french site (bodyfitness-fr) they say to take a watermelon juice at each meal for 3 weeks to increase nitric oxyde by 18% . L-citrulline decrease ammoniac in the body to make L-arginine. Ornithine is also increased.
« Last Edit: 15/10/2008 13:28:23 by martin88 »

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Offline martin88

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1604 on: 15/10/2008 13:39:27 »
Biological functions
In humans, a high-salt intake has long been known to generally raise blood pressure, especially in certain individuals. More recently, it was demonstrated to attenuate nitric oxide production. Nitric oxide (NO) contributes to vessel homeostasis by inhibiting vascular smooth muscle contraction and growth, platelet aggregation, and leukocyte adhesion to the endothelium.[2][3]

http://en.wikipedia.org/wiki/Sodium_chloride

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Offline girlwind

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1605 on: 15/10/2008 15:12:21 »
SOME OBSERVATIONS:

 I am slowly beginning to try Dhea although the lab tests showed it normal.  I have started at 10 mg/day.  It is rough to take on an empty stomach though.
 

I had trouble taking DHEA initially. Then I tried 7 Keto DHEA, and that was much more tolerable for me.
My DHEA levels were down below normal, and now they are up in the low normal range. I take between
25 to 100 mg/day, depending on how tired I am. It is one of the things that helped my POIS and helps
my CFS as well.

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Offline Chewbacca

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1606 on: 15/10/2008 18:53:17 »
So yesterday I was thinking about the relationship between levitra, cialis, nitric oxide and POIS. What came to mind was.....if both levitra and cialis increase the amount of nitric oxide to certain areas of the body, why does only levitra work in alleviating symptoms of POIS? It seems to me that levitra must have a different ingreidient to it than cialis does that helps our POIS symptoms. If we could isolate that ingriedient or ingriedients we might better understand why levitra works and cialis does not. Further, by understanding how those "special" ingriendients affect the body we might be able to understand the mechanisms behind POIS and maybe figure out a more robust "cure" than levitra....hypothetically speaking. What's the difference between the two? I'll look into it and see what I can find out. Maybe the differences are small. It could also be that they have the same ingriegiendts but in different proportions. However, those proportional differences could tell us something as well.

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Offline imre1

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1607 on: 15/10/2008 21:47:10 »
...Germany was the land for sexual research prior to the 1930's and...Hitler leveled it all to the ground.

Good thing it was leveled. If Hitler discovered POIS, he could've figured out a way to give it to the enemy [>:(]

I take it you don't like gays.

Well if you are wondering where your dopamine is at, maybe you should try to do somebody else.

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1608 on: 15/10/2008 21:49:01 »
FROM A PHARMACIST-LAWYER FRIEND RE LEVITRA AND POTENTIAL VISION-LOSS SIDE EFFECTS:

He writes:

" Re the vision loss from Levitra, the manufacturer states:

' Non-arteric anterior ischemic optic neuropathy (NAION), a cause of decreased vision including permanent loss of vision, has been rarely reported......Most, but not all ....had underlying anatomic or vascular risk factors for development of NAION...including age over 50, diabetes,hypertension, coronary artery disease, hyperlipedemia [elevated
cholesterol and/or LDL/and/or triglycerides] and smoking...It is not possible to determine whether the events are related directly to the use of...PDE5 inhibitors (Levitra is one). '

All drugs, prescription and OTC, have potential side effects.  It's a risk/benefit assessment. There are other side effects as well. If you have more than one of the risk factors you might want to weigh the risk vs. the benefit.  The % of reported incidents, to date, is small, but that's cold comfort if you're in that %. "
« Last Edit: 15/10/2008 21:50:48 by demografx »

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1609 on: 15/10/2008 21:56:17 »
...Germany was the land for sexual research prior to the 1930's and...Hitler leveled it all to the ground.

Good thing it was leveled. If Hitler discovered POIS, he could've figured out a way to give it to the enemy [>:(]

I take it you don't like gays.

Well if you are wondering where your dopamine is at, maybe you should try to do somebody else.

WOW, IMRE1, FROM WHAT I WROTE, WHERE IN THE WORLD DID YOU GET THAT I "...DON'T LIKE GAYS" ? THERE IS SOME SERIOUS MISCOMMUNICATION HERE. PLEASE CLARIFY. THANKS.
« Last Edit: 16/10/2008 17:02:31 by demografx »

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1610 on: 15/10/2008 22:07:19 »
So yesterday I was thinking about the relationship between levitra, cialis, nitric oxide and POIS. What came to mind was.....if both levitra and cialis increase the amount of nitric oxide to certain areas of the body, why does only levitra work in alleviating symptoms of POIS? It seems to me that levitra must have a different ingreidient to it than cialis does that helps our POIS symptoms. If we could isolate that ingriedient or ingriedients we might better understand why levitra works and cialis does not. Further, by understanding how those "special" ingriendients affect the body we might be able to understand the mechanisms behind POIS and maybe figure out a more robust "cure" than levitra....hypothetically speaking. What's the difference between the two? I'll look into it and see what I can find out. Maybe the differences are small. It could also be that they have the same ingriegiendts but in different proportions. However, those proportional differences could tell us something as well.

Chewbacca, thank you, this is exactly what I've been thinking for a long time!

The only thing I can add is that - in my one trial of Cialis - the ED "repair" function lasts a long, long time, 36 hours according to the manufacturer I think, while Levitra lasts about 4-6. (not sure about the exact number of hours for both but the Cialis-effectiveness time for ED is far greater than that of Levitra's.)

My conclusion is that the components - that go into Cialis to make it last much longer - somehow nullify the POIS-beneficial effects of the drug.

Keep in mind that the Cialis trial was only a one-shot event. And I was so disappointed that I don't wish to repeat it, unless an outside researcher wants me to.

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Offline John21

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1611 on: 15/10/2008 22:31:26 »
Martin88,
Quote
I heard about L-citrulline in the video of the scientist who's talking about nitric oxyde, but i wasn't able to understand (english deficiency), i was hearing sertraline ... We can find this in watermelon.

Very interesting, thank you for this!

NO from watermelon: http://www.nutraingredients.com/Research/Watermelon-juice-may-be-novel-amino-acid-source


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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1612 on: 16/10/2008 00:18:37 »
Martin88,
Quote
I heard about L-citrulline in the video of the scientist who's talking about nitric oxyde, but i wasn't able to understand (english deficiency), i was hearing sertraline ... We can find this in watermelon.

Very interesting, thank you for this!

NO from watermelon: http://www.nutraingredients.com/Research/Watermelon-juice-may-be-novel-amino-acid-source

Seems like there's a Watermelon/POIS Connection here! Yum.
« Last Edit: 16/10/2008 00:21:51 by demografx »

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Offline hurray

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1613 on: 16/10/2008 01:23:12 »
Hi everyone!

I had the idea that since oxytocin is heavily involved in the chemistry of orgasms, it might be worth trying to supply my body with the necessary ingredients to produce more oxytocin.

Synthetic oxytocin is difficult to obtain and administer, so I thought I'd give Fenugreek a try, which is praised for its oxytocin-like properties. You can buy it at most heath stores I believe.

I took some of it before and after 2 lots of orgasms, and well ...


Wow!


I had work the next day, which normally would be an excruciating trial socially. Not that day it wasn't. I happily chatted to the boss about some complex issues, and spent a lot of the day chatting and flirting with a couple of my female co-workers .... something that would have been impossible under normal POIS circumstances.
The brain fog had been greatly reduced, while the social anxiety component of POIS had been almost completely eliminated! The following day was more of the same.

I don't want to get too excited too soon, I know drugs and herbs can become less effective as they are used more frequently, and the positive effects might not last forever. Also, maybe I have just had two particularly good days, and it will be back to normal during my next potential POIS episode.

If anybody else is thinking of taking it, it sounds very safe - in fact it is an ingredient in certain foods. Only pregnant women should stay away from Fenugreek. I'll carry on posting here as I continue taking fenugreek, I hope I will continue to have good news!

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1614 on: 16/10/2008 01:33:26 »
WOW hurray! Let's keep ALL fingers and toes crossed for repeated success! Very exciting news! Thank you so much.
« Last Edit: 16/10/2008 01:36:15 by demografx »

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1615 on: 16/10/2008 01:50:50 »
Counterpoints, and B_Jim, I just wanted to say thank you again for helping to synthesize some of the information here.

Otherwise we could easily drown in so much of the data that we've accumulated, with no real direction!

And thank you again to everyone for stepping forward and posting your experience, theories and results!
« Last Edit: 16/10/2008 02:01:39 by demografx »

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Offline hurray

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1616 on: 16/10/2008 02:02:36 »
Thanks Demografx, it would change my life so much for the better if the effects keep working, let's hope they do! Thanks for your support :)


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Offline Finally

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1617 on: 16/10/2008 03:54:05 »
Hi Finally,
I'd like to know the quantity of salt you take, and is it iodized salt ?


I am currently using Hain sea salt as a basic table salt.  I use it more than the  average person.  Anyone who sees me eat usually thinks I am going to die but I had my BP taken today and it is normal.  There may be a genetic factor in that. 
The only info is the nutritional label that says a serving(1/4 TSP) provides 45 % of daily Iodine.   If I have an orgasm I will maybe 1-2X that at once with water for "damage control".
I took a daily seaweed  supplement called sea Vegg  for a while and had positive results. I may need to get back on that.
« Last Edit: 16/10/2008 03:55:53 by Finally »

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Offline martin88

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1618 on: 16/10/2008 05:20:48 »
Thanks Finally for this info. You may eventually want to try an organic iodine supplement instead of salt, just to see if it's iodine or sodium chloride. I think sodium chloride can be the effective ingredient or other trace minerals.
Unfortunately the NO (which we don't know if it works for pois) will be decreased with salt.
There is a supplement very rich in salt (not iodized) called quinton plasma, isotonic form is less salty). http://www.plasmaquinton.com/quinton-isotonic.php

Thank you John, i hope it will be useful. I've always been well with watermelon. The seeds have also a good effect on me.
« Last Edit: 16/10/2008 17:24:10 by martin88 »

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1619 on: 16/10/2008 16:09:25 »
INTERESTING (and humorous) NOTE FROM MY PHARMACY-LAWYER FRIEND

...there is a natural product which is touted to be a natural Viagra. I'm not making the name up.  Italian scientists have extracted the active ingredient and claim that in clinical trials it is as effective as Viagra, et al. It is also, allegedly, an herb which is effective for treating artherosclerosis and allergies. It's called Horny Goat Weed [translation from the Chinese]. There was an article about the Italian clinical trials on Yahoo last week. The active ingredient does have a similar effect to the PDE5 inhibitors.

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1620 on: 16/10/2008 16:48:09 »
Thanks Demografx, it would change my life so much for the better if the effects keep working, let's hope they do! Thanks for your support :)

You're more than welcome. It would change my life, too: I'm not wild about Levitra, hoping one day I won't need it!

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1621 on: 16/10/2008 16:50:44 »
Fantastic post Hurray. I hope the anti-POIS effect will be repeated for you.    I like your logical idea to find what is released during orgasm and try to supply it.
I saw that oxytocin deficiency can cause communication troubles. And a lot of us have communication troubles. Especially Day 1 for me.

Up : fenugreek seems not good for hypoglycemic symptoms :/

B_Jim, yes, communication problems have become more apparent to me since I have been paying more attention to my symptoms.

I just remembered a speech I gave years ago. The morning of the speech (Day 1), I was very jetlagged PLUS I had a NE the night before. WHAT A DISASTER THAT SPEECH WAS!!!!!
« Last Edit: 16/10/2008 17:10:41 by demografx »

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Offline imre1

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1622 on: 16/10/2008 18:10:54 »
...Germany was the land for sexual research prior to the 1930's and...Hitler leveled it all to the ground.

Good thing it was leveled. If Hitler discovered POIS, he could've figured out a way to give it to the enemy [>:(]

I take it you don't like gays.

Well if you are wondering where your dopamine is at, maybe you should try to do somebody else.

WOW, IMRE1, FROM WHAT I WROTE, WHERE IN THE WORLD DID YOU GET THAT I "...DON'T LIKE GAYS" ? THERE IS SOME SERIOUS MISCOMMUNICATION HERE. PLEASE CLARIFY. THANKS.

Sory, I was just trying to be funny. Very sorry you couldn't take it that way.

Anyway the idee expressed by this, i thought funny statement, may actually be the case.

That some cases of POIS like dopamine deficiency is actualy caused by suppressed homosexuality.

So sorry if you thought i attacked you personally. I will try to be more discrete next time. 

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Offline imre1

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1623 on: 16/10/2008 18:14:53 »
Hi everyone!

I had the idea that since oxytocin is heavily involved in the chemistry of orgasms, it might be worth trying to supply my body with the necessary ingredients to produce more oxytocin.

Synthetic oxytocin is difficult to obtain and administer, so I thought I'd give Fenugreek a try, which is praised for its oxytocin-like properties. You can buy it at most heath stores I believe.

I took some of it before and after 2 lots of orgasms, and well ...


Wow!


I had work the next day, which normally would be an excruciating trial socially. Not that day it wasn't. I happily chatted to the boss about some complex issues, and spent a lot of the day chatting and flirting with a couple of my female co-workers .... something that would have been impossible under normal POIS circumstances.
The brain fog had been greatly reduced, while the social anxiety component of POIS had been almost completely eliminated! The following day was more of the same.

I don't want to get too excited too soon, I know drugs and herbs can become less effective as they are used more frequently, and the positive effects might not last forever. Also, maybe I have just had two particularly good days, and it will be back to normal during my next potential POIS episode.

If anybody else is thinking of taking it, it sounds very safe - in fact it is an ingredient in certain foods. Only pregnant women should stay away from Fenugreek. I'll carry on posting here as I continue taking fenugreek, I hope I will continue to have good news!

Seems very plausible that this would work. I guess it more simulates an environment between two lovers that are realy into each other.

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1624 on: 16/10/2008 20:06:09 »
Sory, I was just trying to be funny. Very sorry you couldn't take it that way.

Anyway the idee expressed by this, i thought funny statement, may actually be the case.

That some cases of POIS like dopamine deficiency is actualy caused by suppressed homosexuality.

So sorry if you thought i attacked you personally. I will try to be more discrete next time. 

Thanks. I was also partially joking about Hitler's "leveling of sexuality research" , so I thought you may have taken offense. Glad we straightened it out.

Internet communication is not ideal for humor, I know, it's backfired on me before.
« Last Edit: 16/10/2008 20:24:59 by demografx »

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Offline hurray

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1625 on: 17/10/2008 00:44:16 »
Thanks B_Jim, I am hoping very much indeed that fenugreek keeps working for me :)

Great summary of fenugreek's uses, I agree that the reported ability of oxytocin to influence social behaviour is incredible.

Oxytocin nasal sprays are being used by mothers of autistic children to help them socialise more normally, apparently they are very effective!

It makes me wonder if POIS actually makes our brains somewhat autistic temporarily, I have heard that autism is a sliding scale, it can be measured from normal to shy to Aspergers syndrome, and eventually to full-blown autism.

Quote
Seems very plausible that this would work. I guess it more simulates an environment between two lovers that are realy into each other.

Good point Imre1 - you could well be right, earlier in the thread I seem to remember people discussing that the quality of the orgasm had a direct effect on how much they were subsequently affected by POIS.

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Offline Chewbacca

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1626 on: 17/10/2008 01:59:46 »
Guys!!!!!I just read a very interesting article. It's about how drugs like Levitra, Cialis, and Viagra increase the levels of oxytocin in the brain during genital stimulation. What does this mean? Well....if Hurry is trying a supplement that increases the level of oxytocin and it is working for him that would suggest oxytocin imbalance as a possible cause for POIS. If levitra causes an increase of oxytocin during sexual stimulation that also points to oxytocin imbalance as a possible cause for POIS. I'm curious and hopeful to see how things pan out for Hurry. But I think the oxytocin hypothesis is worth investigating in detail since levitra seems to alleviate some symptoms of POIS and apparently so does fenugreek....both of which effect levels of oxytocin!!!! The only question is why does levitra work and not cialis? Could be individaul biochemical differences. Could also be differences in the drugs themselves. However, this all seems very promissing. Nice job Hurry! below is where i found the article. -chewbacca

http://209.85.173.104/search?q=cache:bAmX5M5eZ0wJ:www.news.wisc.edu/14034+does+levitra+increase+levels+of+oxytocin%3F&hl=en&ct=clnk&cd=7&gl=us

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Offline Counterpoints

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1627 on: 17/10/2008 03:24:26 »
B_Jim: What is an IG diet?

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Offline Whoa

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1628 on: 17/10/2008 09:32:56 »
I've definitely had this for a few years. I'm 30 now, and started masturbating up to 7 times a day (and no less than 2 times a day) beginning at age 14. Back then, I didn't have any symptoms of POIS except when I hit upwards of 7 orgasms in one day. I just figured that was what happened when you overdid it.

Fast forward to my mid-20's. After ejaculating I increasingly felt very weak, tired, dehydrated, my testicles felt sore and empty, and my voice cracked and became higher pitched than normal - like an old man's voice - this lasted for a couple days usually. It seemed like, the more and more my balls "filled back up", the symptoms disappeared - I felt more mental clarity, physical strength, energy, happiness, and confidence.

I should also point out: It seems like the more awesome the splash, the worse the sickness. So when I blast a load six to twelve feet I might as well call in sick for work. If it's a weak one, then I'm probably going to be fine within an hour or two. If it were a weak one, but I rub another one out within a short period of time, again it's guaranteed sickness.

While I've never had trouble getting it up, I've always had issues climaxing during intercourse - this was probably due to anxiety, said my doctor, and she prescribed me Levitra - which is why I felt obliged to register and post here today. On Levitra, I can confirm that the POIS symptoms were lessened dramatically post-orgasm. Even after an awesome load, I can still get up and do things. I don't feel paralyzed. However, I've never masturbated with Levitra and only used it for a short while until I was comfortable with my girlfriend - So my testing was limited.

One other thing I've noticed is that I will work out really heavy one day (at the gym and not my on penis). The next day I will indulge on my libido and ejaculate after perhaps 2-3 minutes of masturbation or 15 minutes of sex. Immediately after ejaculating I get a feeling of strong relaxation and relief, then about 5-10 minutes later the muscles I worked out at the gym the day before become extremely sore. Maybe they were even a little sore before ejaculating; however, they are extremely sore afterward. By not having an orgasm, I can literally prevent my muscles from getting very sore if at all.

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1629 on: 17/10/2008 19:17:08 »
WHOA! Clever name! And WELCOME to The POIS Forum! Sit back, grab some popcorn and watch our Forum-member girlwind's video.
http://www.youtube.com/watch?v=UWBxAUC9k1g

And many thanks for posting. We look forward to your contributions as we search for a cure for this messy malady!

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1630 on: 17/10/2008 19:26:40 »
...she prescribed me Levitra - which is why I felt obliged to register and post here today. On Levitra, I can confirm that the POIS symptoms were lessened dramatically post-orgasm. Even after an awesome load, I can still get up and do things. I don't feel paralyzed. However, I've never masturbated with Levitra and only used it for a short while until I was comfortable with my girlfriend - So my testing was limited.

This is a terrific confirmation to have a 2nd POIS sufferer reporting Levitra! Levitra has been my personal cure (50% to 75% alleviation of POIS symptoms) for about a year now. Glad to see that it can work safely for someone younger and not necessarily prescribed for ED!

Whoa, we're also exploring nitric oxide, which is an important component of the Levitra story. Related to that, Forum-member hurray has had success so far with an oxytocin-like substance. Oxytocin is manufactured at orgasm.
« Last Edit: 18/10/2008 04:38:22 by demografx »

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1631 on: 17/10/2008 19:34:57 »
IMPORTANT NOTICE TO ALL: Please see a physician if you wish to investigate Levitra, to see if it is right for you.
« Last Edit: 17/10/2008 19:55:28 by demografx »

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Offline acronym

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1632 on: 18/10/2008 03:27:36 »
Fantastic post hurray on oxytocin and fenugreek. It was something I always wondered about from both a POIS and CFS aspect. There is a well known doctor who has success with some of his patients by giving them oxytocin, but it didnt seem that it worked for all his patients. When I enquired about it with my CFS doc he didnt seem to see the connection in regards to immunity + it was a hormone that had a clrear role for women but not really for men. I didn't push on it as it required regular (I think daily) IV injections. Something like oxcytocin would explain the differences in pois between the sexes. Also its role in social anxiety and appetite helps to support it case, and Chewbacca's post linking it to ED meds was great in helping to make the connection to Levitra.
I've read a couple of articles on it and I get conflicting info on fenugreek. Some say it mimics oxytocin and others say its synergestic and others say it stimulates the pituitary to produce more. Depending on how it works we could get variable results. I've started to trial it.

I've been thinking more on nitric oxide and I'm not so sure now. When I was younger I could hang a wet towel off my boner, and if I had an orgasm, the refactory period was under an hour and I was good to go again. To me this indicates a very healthy level of NO. If we were wiping out our NO levels then it would make sense that POIS would get worse as we get older and that does not seem to be the case.

Its annoying how many symptoms and circumstances are not quite the same for everyone. Some people get fever like effect, some people get diarrhea, neither of which I get. Then some people say ejeculation is a big deal and other say not (for me its not) and then some say an all out orgasm is worse and others say its better (I'm the latter).

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1633 on: 18/10/2008 04:54:26 »
Thanks, acronym. You have some interesting thoughts on Fenugreek and nitric oxide.

The connection between refractory period and NO?

I think we need more research and safely conducted trials.

Symptoms and circumstances are different, but I think the theme of 1) DAYS of postorgasmic symptoms, 2)fatigue and 3) mental fog is fairly consistent. I agree though, it would be nice if there weren't many variations.

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Offline Finally

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1634 on: 18/10/2008 07:06:25 »
Whoa, I have noticed that anything that makes you sore has a recovery  period.  If I have an orgasm before the pain goes away that lengthens the time it to heal.  Perhaps the POIS recovery drains something necessary for healing.   
It seems exercising the day or even hours after may help the POIS effects process along, although no one seems to have the  desire to do much at all.  I wonder if anyone has noticed anything similar?   

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Offline Counterpoints

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1635 on: 18/10/2008 08:17:37 »
Here is a compilation I made.   I also have relevant questionnaire responses compiled, but to see these, you must fill out the questionnaire yourself.

Symptoms vary between sufferers, but there are many most of us have in common. 

Group 1 (Most Common Symptoms)
- brain fog
- intense withdrawal
- intense cravings
- difficulty communicating
- difficulty comprehending
- difficulty focusing
- thick-headed
- slow to respond
- absent mindedness
- short attention span (cannot concentrate for more than 2-3 minutes)
- anxiety
- poor short term memory
- lexical recall affected
- restless/agitated
- lack of creativity
- social phobia
- lack of confidence
- embarrassment
- mental exhaustion
Important notes: *  Symptoms generally last 6 to 70 hours.  Some do not recover as quickly during sleep as when they are awake. After 1-3 days of no orgasm, intense cravings for orgasm can re-appear, but the other symptoms do not re-surface unless stimulated by orgasm.  In a given month, people in this group are afflicted by symptoms between 10% and 90% of the time -- depending on the person, and frequency of orgasm.  Note: no loss of motor control apparent amongst most sufferers.  This is perhaps counter to the dopamine depletion theory.  Levitra has helped two sufferers with symptoms.  Oxytocin appears to be helping some people, and apparently Levitra has been linked with Oxytocin production.  Symptoms have sometimes immediately been alleviated by a subsequent orgasm.


Group 2 (Less common)
- derealisation
- lethargy (physical fatigue)
- cold (day 1), sweats/heat (day 2)
- dizziness
- paleness
- shame
- skin conditions following orgasm. (e.g. dry skin).
- visual disturbances
- lack of spontaneity
- diarrhea (helped by low IG diet)
- hypoglycemia (helpd by low IG diet)
- muscle tremors and spasms.
- depression
- headache
- skin conditions
- insomnia
- hunger and thirst affected

Group 3 (Even less common)
- dark circles beneath eyes
- curvature of spine
- joint pain
- dull pain in scalp
- elevated blood pressure  *(noticed by some members of groups 1 and 2)
- swollen neck glands
- double vision
- aphthous ulcers
- allergies
- mild fear of light
- swollen eyelids, runny nose, flu like symptoms
- dilated pupils
- burning fingertips

Also, very important compiled information:
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg95285#msg95285
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg149009#msg149009

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Offline Counterpoints

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1636 on: 18/10/2008 08:19:06 »
Note: I am currently very busy, and will only be available to post approximately once a week, for the next month.

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Offline Whoa

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1637 on: 18/10/2008 09:11:38 »
Thanks for the greeting demografx. It is good to see an active thread on this topic.

To follow up my earlier post, my Rx for Levitra was 10mg. I had some left over, and tested one out today post-orgasm.

Basically, I woke up earlier than my girlfriend this morning and blasted one off. It was a bad idea(I get POIS symptoms worse if I don't go to sleep immediately after orgasm) and I've had horrible POIS symptoms all day. I just wanted to lay down by myself and read or nap, but I couldn't because there was too much to do, and my girlfriend suggested that later in the evening we'd have sexual intercourse.

So I decided to try taking a Levitra midday to see if it would take away the symptoms. It did not. Perhaps because it is now slightly expired, or because it should be taken before ejaculating. I'll try the latter before my next explosive solo session and see what happens.


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Offline hurray

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1638 on: 18/10/2008 12:04:59 »
Thanks for all the great posts!

I only have a couple of minutes before I go away for a few days, just wanted to say that I have been taking 3 capsules 3 times a day,I am taking Solgar Fenugreek containing 370mg raw fenugreek seed powder and 150mg Fenugreek seed powdered extract.

Thanks again for the support!

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1639 on: 18/10/2008 20:40:49 »

Here is a compilation I made...


COUNTERPOINTS:

BRILLIANT!

THANK YOU!

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1640 on: 18/10/2008 22:45:49 »
Thanks for the greeting demografx. It is good to see an active thread on this topic.

To follow up my earlier post, my Rx for Levitra was 10mg. I had some left over, and tested one out today post-orgasm.

Basically, I woke up earlier than my girlfriend this morning and blasted one off. It was a bad idea(I get POIS symptoms worse if I don't go to sleep immediately after orgasm) and I've had horrible POIS symptoms all day. I just wanted to lay down by myself and read or nap, but I couldn't because there was too much to do, and my girlfriend suggested that later in the evening we'd have sexual intercourse.

So I decided to try taking a Levitra midday to see if it would take away the symptoms. It did not. Perhaps because it is now slightly expired, or because it should be taken before ejaculating. I'll try the latter before my next explosive solo session and see what happens.


Thanks, Whoa. I tried Levitra once or twice _AFTER_wards (but shortly thereafter), and it worked! I was surprised.

It worked, but it did not work as powerfully as taking it _before_hand.

I reported on it here when it happened.

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Offline John21

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1641 on: 19/10/2008 00:28:23 »
I bought some Fenugreek seed last night, twice today I took a single 620mg capsule. This stuff definitely has an effect on my brain, it kinda feels like I'm on an antidepressant or something, although I have to give it some time to see if it is good for me or not. I didn't expect this reaction, I think I'll ease down to one a day. I have not recently experienced orgasm to know if there is any POIS altering effect.

Sparking my curiosity in herbs I did a little searching...has anyone heard of Brahmi (Bacopa)?

Quote
Brahmi has been valued as a cardiac, nerve and brain tonic and widely used by students for improving mental clarity, confidence, intelligence, concentration and memory recall. Brahmi as herbal supplements and tablets have been marketed for super learning, for memory and as a brain tonic. In 1963 research on the brahmi plant identified 2 active molecules: Bacoside A that assists in the release of nitric oxide allowing relaxation of the aorta and veins and blood to flow more smoothly through the body and aids circulation; and Bacoside B, a protein valued for nourishing nerve cells in the brain.
http://myfolia.com/plantings/25

I also sampled some Stevia today, a herbal sweetener, it wasn't too bad on oatmeal, (although I eventually added some maple syrup.  [:)])

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Offline Chewbacca

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1642 on: 19/10/2008 01:33:21 »
A quick note about levitra and oxytocin for those who are taking it as a treatment for POIS. The increase in oxytocin only happens during sexual stimulation. Not sure why this is, but that's what the article I read said that linked oxytocin increase to PDE-5 inhibitors(levitra, viagra, cialis). If an increase in oxytocin is what is responsible for lessening the effects of POIS... if you take PDE-5 inhibitors after orgasm you will not get an increase in the levels of oxytocin!!! This is probably why demografx and whoa had more sever symtoms when they took levitra after orgasm....because the mediating effects of PDE-5 inhibitors only work when you take the pill before sexual stimulation. If you don't, you don't get an increase in oxytocin.

So just remember....take the pill first...then do the deed!!!! - and as always, make sure you have a doctors approval(disclaimer:)

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1643 on: 19/10/2008 01:38:01 »
IMPORTANT NOTICE TO ALL:
Rx, FENUGREEK, AND ALL OTHER NON-PRESCRIPTION SUPPLEMENTS


I would strongly urge a healthcare practitioner or physician's involvement before taking any prescription drugs OR health supplements mentioned here. For example, googling Fenugreek shows that it is used to enlarge female breasts! HOWEVER, we are not physicians or healthcare practitioners here. Please use caution when following someone else's suggestions, no matter how enticing. Everyone's body chemistry is unique.
« Last Edit: 19/10/2008 03:50:09 by demografx »

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1644 on: 19/10/2008 03:51:32 »
A quick note about levitra and oxytocin for those who are taking it as a treatment for POIS. The increase in oxytocin only happens during sexual stimulation. Not sure why this is, but that's what the article I read said that linked oxytocin increase to PDE-5 inhibitors(levitra, viagra, cialis). If an increase in oxytocin is what is responsible for lessening the effects of POIS... if you take PDE-5 inhibitors after orgasm you will not get an increase in the levels of oxytocin!!! This is probably why demografx and whoa had more sever symtoms when they took levitra after orgasm....because the mediating effects of PDE-5 inhibitors only work when you take the pill before sexual stimulation. If you don't, you don't get an increase in oxytocin.

So just remember....take the pill first...then do the deed!!!! - and as always, make sure you have a doctors approval(disclaimer:)

Chewbacca, very good post. Thanks.

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Offline tarkington

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1645 on: 19/10/2008 16:14:52 »
Great News!!!!!!!!

I bought Relora from Swanson Health for a good price (only $7.00).  I then took three capsules per day.  But first let me say that before I started taking Relora I had not had an orgasm for at least two weeks, so I was pretty normal.  I also had started taking Centrum Chewable tablets once a day for about two weeks.  So after taking Relora three times a day for four days I decided to have an orgasm.  I felt just fine and normal.  I encountered no feeling inside me like many people describe feeling after orgasm.  But I did start to feel the onset of my POIS symptoms after about four hours.  BUT, they were reduced to about 10 - 15% of their normal power (instead of feeling terrible -- 9 out of 10 on scale -- I felt around 2).  I was still feeling pretty normal.  And to make things better, these reduced symptoms only lasted for about 4 or 5 hours.  That is so much better than my normal 72 hours.  So to summarize, Relora reduced all of my symptoms to virtually nothing.  I have now had two orgasms both or which followed the same pattern.  I believe this is as close as I can get to a "cure." 

By the way my symptoms included feeling brain fog, anti social, helpless, depressed, confused, anxiety.  I had no physical problems like dry skin or pain (well I did have cold sweats for about 5 hours following orgasm).  all these went away. 

Also, when I first started taking Relora I felt much calmer and less stressed.  I have always been stressed and anxious and this helped.
I HOPE THIS CONTINUES TO WORK THIS WAY!!

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Offline John21

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1646 on: 19/10/2008 20:49:16 »
Well I didn't wake up with female breasts this morning, this is good. [:D] Last night I had an NE (it seemed somewhat small), and today I had zero POIS effects. I am still consuming raw garlic so I can't say if fenugreek is responsible or not, but I am hopful that it turns out to be of assistance.

Good stuff Tarkington, nice to hear you had some positive results. When I tried Relora I was very sensitive to it. It aggrivated my insomnia so I gave up on it.


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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1647 on: 20/10/2008 16:00:40 »
TARKINGTON:

THANKS FOR POSTING

YOUR GREAT NEWS!!

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1648 on: 20/10/2008 16:02:43 »
JOHN,

Congratulations on maintaining breast size!


[;D]

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1649 on: 20/10/2008 22:55:40 »
Last night I had an NE (it seemed somewhat small), and today I had zero POIS effects. I am still consuming raw garlic so I can't say if fenugreek is responsible or not, but I am hopful that it turns out to be of assistance.

John, if you never "escaped" POIS in the past with "small NE" this would be a good sign! (I never escaped it [:-'(]  <<real tears).

Please tell us!
« Last Edit: 21/10/2008 00:06:19 by demografx »