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  4. Post Orgasmic Illness Syndrome (POIS)
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Post Orgasmic Illness Syndrome (POIS)

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Offline martin88

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3720 on: 06/03/2009 03:44:26 »
Quote from: B_Jim on 03/03/2009 06:49:42
I'm day 2 today (25 hours later) .Dispite my post-orgasm supplements (vitamin C + B, bromelain), I have flu-like symptoms (sweats, feverish...). Sunday I ate a lot of high carbs (Family Banquet) : ice cream, pastas, pizzas, cakes, satured fats... I don't say my vitamins and enzyme is useless but the high carbs have a strong and quick negative effect to compare to supplements. I had clear muscle tremors yesterday. My urinary pH is too acid (5 to 6).
Few weeks ago I was ill and I couldn't eat a lot for several days. After this I noticed my social phobia was reduced significantly.
If you don't eat enough food you'll have a lack of vitamins (maybe this is true) but here they say food deprivation can lower catabolic hormones:
- http://cat.inist.fr/?aModele=afficheN&cpsidt=19450718

- same study with more details

Cortisol is a catabolic hormone:
http://en.wikipedia.org/wiki/Catabolism
I'm just wondering if reducing by 25% our food intake could be of any help. Hope I'm not becoming anorexic !
« Last Edit: 06/03/2009 03:56:52 by martin88 »
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Offline CertainlyPOIS

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3721 on: 06/03/2009 03:47:59 »
just wondering i tried dhea, i didnt really notice much but what i noticed was a testicular shrinkage did anybody experience that.
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Offline Christopher

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3722 on: 06/03/2009 04:14:51 »
Your brain on sex

newbielink:http://www.reuniting.info/science/sex_in_the_brain [nonactive]

The orgasmic brain

newbielink:http://www.reuniting.info/science/orgasm_pill_sex_addiction_holstege_all_in_the_mind [nonactive]

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3723 on: 06/03/2009 05:36:26 »
Welcome, Christopher!

Thanks for the article links from Reuniting. Marnia visits here from time to time.


I love this cartoon on one of your links. Is this The Future Of POIS Therapy? [;D]
« Last Edit: 06/03/2009 06:13:48 by demografx »
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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3724 on: 06/03/2009 05:59:28 »
Christopher, please tell us something about yourself!
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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3725 on: 06/03/2009 06:26:09 »
Quote from: neverstop on 05/03/2009 20:52:36

I wonder what is different (aside from duration of action) between Cialis and Levitra? I used a 20mg and did have a headache (which I seldom get) and a flushed feeling but no increased POIS symptoms as you experienced.


To clarify, Cialis did not increase my POIS symptoms. It just didn't work at all. So the letdown felt devastating, emotionally. Failed experiment.

Also, at the time I didn't realize the importance of testosterone, which I was taking erratically via depotestosterone injection, which as you know "spikes". so I might have simply been on the other side of "spike".

Last year I mistakenly attributed all my POIS success (and failure) to Levitra. And then I stopped testosterone altogether, not realizing it was a major contributor to my POIS healing!

Amazing how something so simple became so complicated! Similar to Hurray's experimentation with Fenugreek and DHEA.
« Last Edit: 06/03/2009 06:38:17 by demografx »
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Offline martin88

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3726 on: 06/03/2009 13:05:01 »
Quote from: B_Jim on 06/03/2009 07:25:11
Phosphatidylserine

Scientific study :

Quote
Effects of phosphatidylserine on the neuroendocrine response to physical stress in humans
The data indicate that physical stress induced a clear-cut increase in plasma epinephrine, norepinephrine, ACTH, cotisol, GH and prolactin, whereas no significant change was observed in plasma dopamine and glucose. Pretreatment with brain cortex-derived phosphatidylserine significantly blunted the ACTH and cortisol responses to physical stress.

Naturopaths/nutritionists think :
- Phosphatidylserine can modulate release of cortisol and ACTH
- Phosphatidylserine blocks the excessive response of  adrenals to a stress
- "repair" HPA axis
- The treatment must be prolonged at least 3 months (?)
Thanks a lot B_Jim for posting this. I'm wondering if it makes a difference to take brain cortex-derived PS as it's mentionned in the study.
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Offline Ambient123

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3727 on: 06/03/2009 13:30:06 »
Neverstop, apologies for bombarding you with questions. I have one more

On a scale of 1 to 10 (1 = No difference, 10 = Great effect), how much of a difference did the Tyrosine make to your POIS symptoms?

(P.S, im aware of the fact that Tyrosine is only one of many treatments you are taking. I am asking for its effect as a singular treatment)

Thanks 
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Offline neverstop

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3728 on: 06/03/2009 17:48:22 »
Ambient123,  That's all right,,  (though I will disclose now, typing is a bit difficult for me with some paralysis from the spinal cord injury so I may be inactive here at times) I'd have to say that it would be impossible to give you an L-Tyrosine only rating (Singular) as I've been working on this (or more accurately my even bigger symptoms from SCI) for years with incremental successes that I keep up with. So, when I tried the L-Tyrosine this wasn't done with the same severity of POIS symptoms I once had. The only way I could really give one singularly would be to stop the various things (the "T" DHEA. assorted neurotransmitter precursor supplements, as my "primaries" to mention) I utilize. I'll give you an answer though,  this way,,,,,,, of the remaining post "O" symptoms of decreased mental clarity, depression, and some physical energy depletion, it would be an 8 I would say. (we can always wish for more right) It was as though I "hit the mark" with this one thing which was very satisfying indeed.

Hope this helps some,
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Offline neverstop

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3729 on: 06/03/2009 17:51:30 »
Quote from: demografx on 06/03/2009 06:26:09
Quote from: neverstop on 05/03/2009 20:52:36

I wonder what is different (aside from duration of action) between Cialis and Levitra? I used a 20mg and did have a headache (which I seldom get) and a flushed feeling but no increased POIS symptoms as you experienced.


To clarify, Cialis did not increase my POIS symptoms. It just didn't work at all. So the letdown felt devastating, emotionally. Failed experiment.

Also, at the time I didn't realize the importance of testosterone, which I was taking erratically via depotestosterone injection, which as you know "spikes". so I might have simply been on the other side of "spike".

Last year I mistakenly attributed all my POIS success (and failure) to Levitra. And then I stopped testosterone altogether, not realizing it was a major contributor to my POIS healing!

Amazing how something so simple became so complicated! Similar to Hurray's experimentation with Fenugreek and DHEA.

Demo, Thanks for the clarification, I get you now. Yes, multiple solutions in combination for multiple symptoms can be difficult to sort out once you are a ways along.
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Offline longwalkhome

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3730 on: 06/03/2009 23:30:09 »
I'm not sure if this has been brought up already, but there seems to be a very small group of women who react allergically to semen. But the question is: Can the male body regard something that is produced by itself as hostile or unknown, thus leading to some sort of anaphylactic shock? Or to put it short - can a man be allergic to his own sperm? Unfortunately I don't know anything about this sort of thing, so I'm sorry if this sounds childish to some of the more well-read members on this board ...

http://www.essortment.com/articles/semen_allergy_100017.htm [nofollow]
Quote
What kinds of allergic reactions can people have to semen?
People can have localized problems after immediate contact with semen. They can have burning, pain and swelling that can occur for long periods of time. Typically it affects the outer vaginal vault area, though it can also affect the inner vault. Some women describe severe burning and pain, where it feels like 1,000 needles have been injected in them at one time.

Quote
What in semen are people allergic to?
People are allergic to proteins in semen. We don't really know which proteins are responsible at this point. Many of the proteins associated with the semen allergy are believed to be common proteins found in all semen, but it's also possible for people to be allergic to a protein that is unique to an individual.

The systemic reaction is believed to be linked to a specific IgE antibody that is triggered by the protein; this antibody response is similar to what occurs in people who have seasonal allergies. There are probably multiple causes of the localized reaction. A delayed type of hypersensitivity response similar to what occurs with poison ivy may be involved.

From http://www.ncbi.nlm.nih.gov/pubmed/81816?dopt=Abstract [nofollow]:
Quote
A case of an anaphylactic type of allergy is reported with pruritus, mucosal edema, asthma and shock symptoms which developed in a 26 year old female against her husbands sperma fluid. Symptoms and test results are compared with those of six other published cases. Results of skin tests obtained with a fraction of sperma plasma separated by chromatography are indicating that the antigen is of protein nature with a molecular weight of about 14.100. A molecular weight between 12.400 and 24.00 has also been reported in the literature.
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Offline longwalkhome

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3731 on: 06/03/2009 23:35:34 »
I'm sorry, I just found out that there's already been a post about this ... But maybe it makes at least a little sense to bring it back up again anyhow.
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Offline Ambient123

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3732 on: 07/03/2009 00:38:45 »
Hey guys.

This is a random question, but does anyone know what happens to Thyroxine (For the thyroid gland) levels after an "O"?
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Offline Defsync

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3733 on: 07/03/2009 00:39:10 »
OH MY FREAKIN LORD

let me tell you all i've been looking for information on this MY WHOLE LIFE.

I FINALLY FOUND A THREAD ADDRESSING THIS.

what the op describes in his first post i've experienced my whole life as well.

okay so $20,000 of brain MRI and EKG found nothing. I havent gone as far as an endo makeup, though I should in the near future. I haven't read this entire thread yet, i'm going to right now.

THIS SYNDROME IS NO JOKE FOR PEOPLE WHO HAVE IT.

I cannot function at WORK for a few days after a climax of any kind. Try telling your boss that's why you are screwing up the last couple days. Also try telling your wife or girlfriend that no, you really dont like sex cause it !@#$!#@ your head up in an utterly frightening way. You want to know what it's like? Here, let me shoot you up with some nice tranquilizer that lasts for days and see how much fun you have.

what gets hit?

memory recall
concentration and focus
vocal communication

I have been abstinent most of my life because of it. Do I really mind being totally abstinent? Not at this point, I'm use to it. But it would be great to please a girlfriend al naturale without having to suffer like this.

Man I cant wait to read this entire thread. Im saving it and I'm shoving it in my doctor and neurologists face.
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Offline underwater

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3734 on: 07/03/2009 01:21:12 »
Nice to see new members with great contributions and positive therapies.
I wish my symptoms were similar to the vast majority of POIS sufferers.
Mine is like a slow panic attack with tingles, sweats, depression and a general amped up feeling. I keep this anxious, tense condition for about 4 days. I don't get this severe exhaustion and cognitive impairment. Yet like everyone else, I don't like to socialize at all during this period. During my POIS, I have to avoid arousal or I get worse. There is a bit of madness to mine. As a consequence of my symptoms, I am still pursuing the auto-allergic side of things. Another term for me might be a hyperstimulatory response to orgasm and arousal. Something (some chemical/s) stay in my system and don't let me relax!!!!! Mine is almost opposite of everyone's main symptoms.
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Offline Ambient123

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3735 on: 07/03/2009 01:35:42 »
I have been looking into what happens to thyroxin levels after orgasm, but have still found nothing.

Does anybody know what happens to Thyroxin levels after an orgasm?
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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3736 on: 07/03/2009 02:00:23 »
Quote from: longwalkhome on 06/03/2009 23:30:09

I'm not sure if this has been brought up already, but there seems to be a very small group of women who react allergically to semen. But the question is: Can the male body regard something that is produced by itself as hostile or unknown, thus leading to some sort of anaphylactic shock? Or to put it short - can a man be allergic to his own sperm?


Longwalkhome this sounds reasonable. Thanks for the links. Maybe testosterone - by way of helping (pushing?) sperm regeneration - prevents this allergic-type reaction?
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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3737 on: 07/03/2009 02:13:20 »
Quote from: Defsync on 07/03/2009 00:39:10

I FINALLY FOUND A THREAD ADDRESSING [POIS].


Defsync, welcome to the POIS thread of The Naked Science Forum!

Thank you for sharing your experiences. Most of us were incredibly/pleasantly surprised as well to find this forum after years alone in "the wilderness", where most people just don't have a clue: friends, family and medical "professionals" alike.

We look forward to more of your posts.

Here are some POIS forum resources which may be helpful to you:

Please see "B_Jim"'s POIS Forum Summary of All Cases, here as well as others on the Web:
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg149009#msg149009

"Girlwind" has created an excellent POIS Video:

And filling out the POIS survey created by "Counterpoints" will enable you to share POIS information and details with others here. This will also enable us to work more easily with outside researchers by having more organized data available about us:
http://pois.olympe-network.com/

POIS Research Study

We have a copy of the first and only study on POIS by Dr. Marcel Waldinger,MD and Dr. David Schweitzer, MD.

If you want a copy (PDF), send "Pyropeach" a Private Message with your regular email address and he'll send you back the PDF.

To send a Private Message, click on "Messages" at the top of this page. At the Messages page, click on "New Message". From that point on, it works just like posting a message here, except that it only goes to the person(s) you designate.

Remember to put a quote around the recipient's name, e.g., "pyropeach".

New York Times article,

January 20, 2009
Mind
Sex and Depression: In the Brain, if Not the Mind
By RICHARD A. FRIEDMAN, M.D.
http://www.nytimes.com/2009/01/20/health/views/20mind.html?_r=1&scp=1&sq=friedman%20sexual%20January%2020&st=cse


In addition to serving our own informational interests, the above can be useful for you to show the medical world - who often shows little understanding and is sometimes skeptical of our condition - that POIS has scientific underpinnings and that POIS is not "just another psychological problem" related to sex - to be treated by the psychiatric/psychotherapist community.

Also, it can be helpful when dealing with medical professionals to point out the successful existence of this forum for over 2 years, which has attracted over 100 POIS sufferers worldwide who have posted here, plus nearly 250,000 page visits. Not bad for a rare malady!

Again, Defsync, welcome!
« Last Edit: 07/03/2009 02:37:53 by demografx »
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Offline Defsync

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3738 on: 07/03/2009 07:15:00 »
Thanks. I havent really shared yet =) I am still gathering my thoughts on my experiences with POIS and things i've tried. It will be a day or two till I post more on that.

But in the meantime, what I think the result of all this collective research is a "portfolio" of everything that's been learned, that we can submit to research clinics and medical universities around the country, on hopes that some clinic or some aspiring student would find interest in a study to learn more about POIS.

one place i would send such a "portfolio"
http://my.clevelandclinic.org/endocrinology/research/default.aspx

in my city we have one of the top medical universities in the nation. i would also send it there. Also, why is all this information in a forum thread? Why doesn't POIS have its own website already? A place where we have all the information gathered and digital copies saved to the server, with links to where it all came from, with each person's experiences listed, something a bit more organized so if we are trying to get medical professionals to do research at the very least we can point them to the website.
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Offline John21 (OP)

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3739 on: 07/03/2009 13:25:04 »
Another NE (wow, what a string!)

This time I am affected, garlic is not saving me (but perhaps helping). I would give it a 4.5 on a scale 1-10.

Quote
I wish my symptoms were similar to the vast majority of POIS sufferers.
Mine is like a slow panic attack with tingles, sweats, depression and a general amped up feeling. I keep this anxious, tense condition for about 4 days. I don't get this severe exhaustion and cognitive impairment. Yet like everyone else, I don't like to socialize at all during this period. During my POIS, I have to avoid arousal or I get worse. There is a bit of madness to mine. As a consequence of my symptoms, I am still pursuing the auto-allergic side of things. Another term for me might be a hyperstimulatory response to orgasm and arousal. Something (some chemical/s) stay in my system and don't let me relax!!!!! Mine is almost opposite of everyone's main symptoms.


Underwater,
I can identify with this, but without sweats or depression. Being somewhat "in it" presently I will try to explain what I am experiencing.

I also feel mentally excited, like my mind is swimming in something stimulating, slowing my thought and making me spaced out. I am less available for communication because of this mental overload. With my social ability degraded I become hyperfocused on trying to act normal. The situation makes me want to hide under a rock to avoid embarrassment, as stress can only make the problem worse. With time the only "way out" I feel helpless and dejected. Solitude is welcomed.

Edit: After the last couple of NEs I have had lots of muscle twitching, this time in my nose area.
« Last Edit: 07/03/2009 13:32:39 by John21 »
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