[Pablo445]

He also told me that one hit of cocaine[ i never did cocaine or any drugs] will use up the bodies supply of dopamine and it talks a full year for the dopamine level to be restored. I mention this only because it shows how important and frail this neurotransmitter is, and , just in case anyone has done this drug may explain possibly why they have pois and that quiting such drugs may reverse your symptoms over time.

That is interesting. I only tried cocaine once about 35 years ago but for a whole weekend! I felt so incredibly good that I decided to never touch this again because I knew I would not be able to live without it. The downside is that I was unbelievably tired and exhausted afterward. For the first and only time in my life I actually slept for 24 hours in a row (from 8 am to 8 am) and felt completely out of it for several weeks. Yes it did feel like POIS in many aspects. But I came back to normal and never touched that stuff again (or any other recreational drug for that matter). It gave me a vague personal understanding of how someone can easily get hooked to that substance. The Clark Kent in myself enjoyed being Superman for few days for sure!  

[Z_one]

Unbelievable! CNN has just announced that Oprah has quit her talk show!

Z_one, yes, I heard that Oprah quit because she knew that we were about to contact her!  []

"Oh no, it's the Guys From POIS!"

Z_one, all's not lost. Oprah will stay thru 2010. And 2011 she'll simply do her own TV thing, raking in billions more. So    she is still a viable prospect!

....indeed!  []

[Dean93]

http://www.neuroassist.com/Neurotransmitter-Depletion.htm

I've been reading up on that website, and what it basically says is that Tyrosine (precursor to Dopamine) depletes Serotonin, and 5-HTP (precursor to Serotonin) depletes Dopamine. The are two parts of a system, and they must be in balance, otherwise one will inhibit the other, and over time, one may shut down the other, and treatments will become ineffective. This would explain why both tyrosine and 5-HTP stop working for people. So, while not exact, wouldn't it be much more effective to take them both, on and off?

I know I'm oversimplifying.

[Pablo445]

Dopamine and Omega 3

What has been your experience with a daily high dose of Omega 3 (1,500 mg EPA + 1,000 DHA)? Few years ago I was told my Omega 3 fatty acids level were very low. I supplemented for a while but I did not take it seriously and only took small quantities. Now I am trying again - I just got started. According to what I have read if it makes any difference I should start feeling it in about 6 weeks.

From The Omega3 Connection by Andrew L Stoll MD, page 117
The omega-3 fatty acids are an integral part of the structure and function of the brain. The brain does not function well unless adequate amounts of omega-3 fatty acids circulate in the bloodstream and are incorporated into cell membranes. Omega-3 fatty acids also appear to influence the brain chemicals involved in antidepressant action. For example, French scientists have shown that rats deficient in omega-3 fatty acids had more receptors for the neurotransmitter serotonin and a corresponding decrease in dopamine in the frontal cortex. The direction of the changes in these neurotransmitter systems is consistent with some human models of major depression. Not surprisingly, other scientists have observed that increasing the dietary intake of omega-3 fatty acids boosted the levels of the neurotransmitter dopamine in the frontal cortex of rats. In humans, increased dopamine in the frontal cortex increases drive and motivation, attributes lacking in the depressed person.

[demografx]

Unbelievable! CNN has just announced that Oprah has quit her talk show!

Z_one, yes, I heard that Oprah quit because she knew that we were about to contact her!  []



"Oh no, it's the Guys From POIS!"

Z_one, all's not lost. Oprah will stay thru 2010. And 2011 she'll simply do her own TV thing, raking in billions more. So    she is still a viable prospect!

....indeed!  []

Z_one, so..........does this mean you'll contact Oprah? And Larry King? (Last year I ran into Larry King outside his office, but I was tongue-tied! [pois lol] )

[Dean93]

tinyurl . com / PostOrgasmicIllnessSyndrome and /poisforumstart will now get you to page 1 of the forum.

[demografx]

Thanks, Dean!

[Dean93]

No problem Demo

[Holden F. Anmar-Dey]

Hello my fellow POIS sufferers.
I would like to extend a hand of friendship and comradary to everyone who participates in this forum. I would also like to say how grateful I am for this resource that has been like a beacon of light, that has pierced the long night and given me hope.
To the regulars who keep this forum alive I give an extra-big thank you for all that you have done in keeping us informed on your trials and tribulations and bringing our affliction into the light of day.

It may not be an auspicious start to have my first post to be that of praising or "ass-kissing" but every word is true and genuine.

You'll probably be seeing me around.

[Z_one]

Z_one, so..........does this mean you'll contact Oprah? And Larry King?[/b] (Last year I ran into Larry King outside his office, but I was tongue-tied! [pois lol] )
 

I'll do my best man,,,but meanwhile try hitting onto Dr.Phil and Snoop Dog....I am sure the latter might be more than pleased to share his POIS experience.................  [O8)]

[Z_one]

.....what a relief.....just took a capsule of Gotu Kola...no more brain fog and much improved mental focus.....apparently Gotu Kola boosts the brain's neurotransmitters....no more need for "Adderall" to relief ADD.....Love U mother nature!

[Z_one]

Hello my fellow POIS sufferers.
I would like to extend a hand of friendship and comradary to everyone who participates in this forum. I would also like to say how grateful I am for this resource that has been like a beacon of light, that has pierced the long night and given me hope.
To the regulars who keep this forum alive I give an extra-big thank you for all that you have done in keeping us informed on your trials and tribulations and bringing our affliction into the light of day.

It may not be an auspicious start to have my first post to be that of praising or "ass-kissing" but every word is true and genuine.

You'll probably be seeing me around.

Welcome aboard!

[demografx]

Holden F. Anmar-Dey, welcome to the POIS thread of The Naked Science Forum and thank you for your very kind words of introduction!




Here are some POIS resources which may be helpful to you:

Our new POIS Information Website, built by "mat780", is here:
http://sites.google.com/site/POISwebsite/

Please see "B_Jim"'s POIS Summary of All Cases, here as well as others on the Web. This includes remedies that we have tested, and results.
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg149009#msg149009

"Girlwind" has created an excellent POIS Video:

And filling out the POIS survey created by "Counterpoints" will enable you to share POIS information and details with others here. This will also enable us to work more easily with outside researchers by having more organized data available about us:
http://pois.olympe-network.com/

POIS Research Study

We have a copy of the first and only study on POIS by Dr. Marcel Waldinger,MD and Dr. David Schweitzer, MD.

If you want a copy (PDF), send me a Private Message with your regular email address (use "AT" instead of "@" ) and I'll send you back the PDF.

To send a Private Message, click on "Messages" at the top of this page. At the Messages page, click on "New Message". From that point on, it works just like posting a message here, except that it only goes to the person(s) you designate.

Remember to put a quote around my name, i.e., "demografx".


New York Times article,

January 20, 2009
Mind
Sex and Depression: In the Brain, if Not the Mind
By RICHARD A. FRIEDMAN, M.D.
http://www.nytimes.com/2009/01/20/health/views/20mind.html?_r=1&scp=1&sq=friedman%20sexual%20January%2020&st=cse

- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

In addition to serving our own informational interests, the resources listed above can be useful for you to show the medical world - which often shows little understanding and is sometimes skeptical of our condition - that POIS has scientific underpinnings and that POIS is not "just another psychological problem" related to sex - to be treated by the psychiatric/psychotherapist community. This can help fight the immediate reaction of some: IT'S NOT "ALL IN OUR HEADS"!

Also, it can be helpful when dealing with medical professionals to point out the successful existence of our rapidly growing forum for nearly 3 years, which has attracted over 150 POIS sufferers worldwide who have posted here, plus nearly 500,000 page visits. Not bad for a rare malady!

[demografx]

Holden F. Anmar-Dey, this post will help you find information about POIS that we have already discussed, by tailoring a Google search to this forum:


SEARCH THE FORUM WITH GOOGLE

We have an overwhelming amount of data: over 2 years' worth of posts from 150+ Forum members, and an additional 150 POIS sufferers found on the Internet, but not on this forum.

In the Google search box, type
whatever-it-is-you're-interested-in-finding-out[space]POIS[space]site:http://www.thenakedscientists.com/

for example, I tried
demografx POIS site:http://www.thenakedscientists.com/

and 1,000+ results came up for "demografx" within the Forum.

be careful with spaces (you can use them before the word "site") and no-spaces (everything after the word "site")

Google even provides you results with the Message# for each result. But Message #'s do change, so be patient and look for the approximate Message#.

[Z_one]

I am going to see three endos in a row this week..in an aim to put an end to this misery....

I will be bringing up several theories to the table among which the following....

1- Hypothalamus disorder/ tumor.
2- Pituitary gland disorder/tumor
3- Autoimmune Endocrine disease and related.
4- Adrenal gland/cortex disorder/exhaustion.
5- Deficiency in one or several brain transmitters.
6- Any suggested theories by the docs....

P:S Thyroid disease does not seem to apply to me since have already checked on hypo and hyper both were negative......while my preliminary blood tests taken on Day1 did not reveal any abnormalities so far ( FSH, LH, Prolactin, T, ect...all within normal ranges!)....which is why I am gonna continue further in raising the roof....

I'll be pointing out at this forum as reference as well as the youtube video.....while will do all necessary tests...including blood, scan, MRI and others....

Will surely share with you all the outcome of my raid....and we're not giving up!


Kind regards,

[demografx]

I am going to see three endos in a row this week..in an aim to put an end to this misery....I'll be pointing out at this forum as reference as well as the youtube video.....

Wow! Wonderful, Z_one! 3!!! []

May I suggest something? It helped me a lot when meeting and establishing credibility with a top endocrinologist, who I am now working with:

For medical credibility, show the original POIS paper written by Dr Waldinger, (MD) and importantly, his co-author, Dr Dave Schweitzer, who is an endocrinologist(!)

I think it's difficult for an endocrinologist to outright dismiss another endocrinologist!

I can only email you a copy of it, PDF's don't attach to PM's here at the forum.

At least, here is an Abstract
http://cat.inist.fr/?aModele=afficheN&cpsidt=13719471

[Porke]

I am going to see three endos in a row this week..in an aim to put an end to this misery....

Cant wait to see what you find. Good luck

[demografx]

Welcome back, Porke!

[GoingCrazy]

Just had an MRI and MRA taken, results will be back in a few days.  What I've noticed that was really weird as i went into the MRI machine, I was all fine and all as I was in it, and then the noises started (when they were actually scanning), then i had pretty much instantaneous blurry vision, continuous for 40 minutes.  I haven't researched much yet on blurry vision caused by mri, don't know if it really is a side effect or not.

[JonJen99]

Could POIS simply be a severe symptom of Adrenal exhaustion or adrenal disease rather than being a disease itself?

Some causes of adrenal disorders are Cushing's syndrome, hypothalamic disorders, pituitary gland disorders, pheochromocytoma and benign and cancerous adrenal tumours.


The reason why Iam thinking of that is because sexual exhaustion and adrenal fatigue are suppose to be very much interrelated ...and with very common symptoms....

Also last month I totally abstained  for 3 weeks in a row...after which I noticed that POIS was 90% cured after the first time....When my sexual activity resumed and increased in frequency ( Four times and above within the fourth week)...POIS was back....I guess it was an false early Hurray....but apparently with a pause, my overall body & metabolism have dramaticaly improved....

By the way, I had done a complete blood test including Hormonal & Immune system check three weeks ago,,,both my Endo & Generalist doctors think that all test are normal,,,,which only makes me shift again my focus to the adrenal fatigue theory,,,since apparently unless adrenal fatigue is severe..it is hard to detect with routine tests....

On the other hand, I am also considering a hypothalamus/pituitary gland disorder which only gets manifested during release of sexual hormones....I am still inquiring & researching with regard to that,,,,


B_Jim sorry for not replying to ur PM earlier...I was inactive for a while...as to answer u..my symptoms are similar to everybody else but without the flu symptoms ( I thankfully never got those). Therefore I beleive those who have flu symptoms are more or less dealing with an auto-immune disorder such as Addison disease or others...

My symptoms are mainly:

1- Excessive fatigue (Impossible to wake up early the next day!)
2- Fast heart palpitations
3- Weight & muscle loss
4- Eating disorder/ Cravings.
5- Brain fog
6- All senses get confused.
7- Low blood pressure.
8- Anti-social mood.

If I would to put a title I would choose: " The 72hrs body crash!"

Hope this helps.....Also with regard to Black seed oil or Nigella Sativa..it personally helps me alot....it is a general tonic and cure all for the body and works well with Ginseng and Tribulus....

In addition, at a certain stage , Maca worked like magic for me,,,somehow after 2 weeks of use it appears to have completely lost its effectiveness...like a reverse effect or something from overuse....

Tribulus & Ginseng has proven the most effective for me, while Fenugreek, Zinc & Garlic were useless....

I still have not tried Relora nor Rhodiola.....ordered them from the US.

Hope this helps....



Peace.

Wishing you the best on your success with Rhodiola . . . I've had some great results using a US-brand of Rhodiola (Mind Body & Spirit). I combine it with an adaptogens blend called ENERGY RESERVES, which works great to supplement the Rhodiola.