[demografx]

The goal was not to point out @ the credentials of the author but @ the neuro-transmitters deficiency theory

As you can see from my earlier post, I do not attack the theory (which you postulate as more of a "given" with your definitive equation statement, no qualifier). I'll say it again: I'm 100% in favor of investigating neurotransmitters-and-POIS.

But why not pick a credible, trustworthy, and plausible author and website to quote?

You can't separate a statement from its environment. I know this example is extreme, but perhaps it will make it more clear: If a serial killer wants to give me advice on morality, I think I'll pass.

There's no way in the world at this forum that I will encourage that kind of extremely questionable, integrity-lacking information sourcing, no matter how well it suits the opinion of the poster.

[prism]

Just seen an interesting programme on TV about super tall people.

It featured the (previous) tallest man in Britain at 7ft 5in.
They said his 'giantism' was cause by a tumour on the Pituitary gland.
The tumour (now removed) caused years of his Pituitary Gland being over-active causing his great height and large bones etc.

I watched the programme because I am 6ft 4in.
I shot up in height when puberty kicked in (in freakishly quick way).

Theory of mine..
I am thinking now of the links to my testicle problem and the links to the endocrine system/Pituitary gland. As my testicle was 'over-worked' during POIS as a teenager, this surely would have made my Pituitary Gland be over-worked too, which now explains why I shot up in height in such extremely freakish manner as a teenager. 
I have noticed for a longtime during pois i felt more lanky.

The function and state of the Pituitary Gland has been mentioned alot in relation to POIS and on the forum.

Of course, not all will be tall, but it be interesting if anyone relates to this.

[demografx]

Neurotransmitter testing

Like others here, I have been fascinated by the possible link between neurotransmitters and POIS, but to my knowledge, the state-of-the-art in testing is not accurate for the general population.

My understanding is that there are some nascent tests emerging, but that they are extremely expensive and not generally available to the public.

My main source for this is a top endo I have been working with at a major university medical research center.

Does anyone here know about some valid testing?

[demografx]

The function and state of the pituary Gland has been mentioned alot in relation to POIS and on the forum.

Of course, not all will be tall, but it be interesting if anyone relates to this.

db, very interesting post. Not sure you were here yet when I discussed it, but my prolactin count was sky-high (10X the average).

The first reaction of my endo was to do an MRI of my brain, with a focus on my pituitary gland.

The MRI didn't show anything special (a partially empty sella), so I was on my own again.

I was lucky in finding out by just reading wikipedia that Rx drugs can raise prolactin, and Reglan was named, so I got off it, with the endo's blessing, and I was "cured" of sky-high prolactin! It's now average range.

But I wish I were as tall as you []

[Dean93]

Guys read this link very carefully and you will understand why POIS is the result of Neuro[trasmitter]s deficiency...
http://cure-erectile-dysfunction.org/symptoms-of-sexual-exhaustion

What are the credentials of this author, a "Dr" M. (no full first name shown?) Richards, a "urologist" (no MD?). An MD education is required to call oneself a urologist, see http://en.wikipedia.org/wiki/Urology 

And it seems highly unlikely that a urologist would be aligned with a health-supplement business.

On the article author, I found nothing at all about him (her?) on Google. Usually, there are multiple Google  listings from one or more data collection/reporting services on health practitioners. At least for any one of the many I've visited over the years.

The website sells health-supplement products, to "cure" the ailments that they write about. A red-flag conflict of interest that casts serious doubt in my mind about any articles they write.

Last, when I clicked on the website's "About Us" section, a very terse, nondescriptive 2-liner came up, witten by "Anonymous".

The goal was not to point out @ the credentials of the author but @ the neuro-transmitters deficiency theory.....and this article explains it extremely well from a biological angle.....

In addition, if you examine the website of the "International society of sexual medecine" and search for POIS you will notice that all the doctors point out directly or indirectly to neuros deficiency through ADD/ Anxiety disorder/ Antidepressants....ect.... That in addition to many similar remarks posted on this forum....

Finally, again credibility is relative to each person....for me no one has provided me with a concrete straight forward answer nor explanation so far....therefore following tons of reading and research and endless back and forths to endos, uros, and neuros....even my own personal conclusions point out to neuros deficiency.....since auto-immune, STD's and hormonal imbalance are pre-existing disorders & are ruled out by simple elimination....the Neuro-Parasympathic system is the only feasible biological option that can and is still under the spot light.....naturally you're free to think otherwise.....but keep in mind that what we are dealing with is not like Mathematics...so there's no simple equation....it's more or less like trying to point out at a rare never seen kind of fish within a whole Ocean! This is how vague to doctors and sufferers POIS has been so far!

As to confirm even more the neuros deficiency...I would like to report again huge improvements using herbal MAOIs & SSRIS on a constant basis....thx God it seems my brain neuros are replenishing quickly....and Im lovin' it!

Hey Z_one, it's good to know you're doing well but you should know now rather than later that MAOI's and SSRI's aren't "replenishing" anything.

[demografx]

                       


Come on over!
http://forums.delphiforums.com/POIS/chat

[demografx]

"Zinc is an essential mineral needed for the production of testosterone,"  (demo?) 

GC, thanks! (But careful w/quotes from sellers : - )

edit - GC, I take back my comment above about "sellers", I looked too quickly at first. They do appear to be pretty good neutral sources, and more importantly they spell out exactly who they are. Thanks again!

[demografx]

Vitamin C reduces blood pressure

The dosage is high (3 grams) but the effect is quick.

This is great, B_Jim. Thanks!!

[demografx]

My latest POIS episode

This week was one of my worst episodes since treatment began about a year and a half ago. I attribute it to major stress. This is the 2nd time it happened. I think I just need to be more careful with my environmental situation AND frequency.

Still, no comparison to pre-treatment. Even at it's "worst", I think I'm extremely fortunate.

Thanks all for being part of the platform that enabled a major positive life change for me, even after 30+ years of POIS agony and being hopeless about it.

[Z_one]

Has anyone tried Astralagus &/ or Ashwaganda?

[daveman]

....even my own personal conclusions point out to neuros deficiency.....since auto-immune, STD's and hormonal imbalance are pre-existing disorders & are ruled out by simple elimination....

none of those disorderes are necesarily pre-existing... Each one of them can be initiated by a change caused by some external event, even though we are not aware of the occurance of such.

An auto immune reaction or hormone imbalance could be caused by an operation or injury which effects a balance in the endo system for instance.

I'm not so sure that my case isn't one of those. I wouldn't rule out neurotransmitter disfunction either, whether it be just that or in conjunction with something else (like auto-immune disorder). I wouldn't be surprised at all that a neuro transmitter disorder could be a side effect of an auto-immune problem. Immune system attacks could well cause adverse effecs on the neurotransmitter system.

One thing I've come to terms with, especially after coming to this forum, is that this is not all cut and dried. The proffesionals don't have answers for that very reason.

The problem with POIS is that it's very difficult to distinguish the chicken from the egg. It's all too easy to accuse the symptom for the cause.

 

[demografx]

It seems one of possible diagnostic for this problem is 24 hours catecholamines dosage in urine.

So, why not such a test in-Pois to show a supposed abnormal catecholamines activity ?

B_Jim, would it be possible for us to test catecholamines activity when we go for other tests? For example, when I see my urologist - and my nephrologist - they always collect urine samples.

Can it be blood tested? (All my hormonal testing is done via bloodwork).

Can they request this from their laboratory or would it be a special diagnostic?

[demografx]

The problem with POIS is that it's very difficult to distinguish the chicken from the egg. It's all too easy to accuse the symptom for the cause.
 

Very well put.

[demografx]

Has anyone tried Astralagus [sic] &/ or Ashwaganda? [sic]

2 good info sources

Astragalus
http://www.pdrhealth.com/drugs/altmed/altmed-mono.aspx?contentFileName=ame0011.xml&contentName=Astragalus&contentId=174

Ashwagandha
http://www.pdrhealth.com/drugs/altmed/altmed-mono.aspx?contentFileName=ame0203.xml&contentName=Ashwagandha&contentId=365

[Dean93]

Z_one, I'm trying Ashwagandha next, its in the mail. I'll let you guys know how it goes.

[demografx]

Hey Dean, wash it [Ashwagandha] down with blueberry juice!  []

[Dean93]

Well, the word Ashwagandha is Sanskrit for "horse's smell", so I might have to! Its actually supposed to give you the strength of a horse.

[demografx]

I could use that strength!

[Defsync]

hey demografx, i just finally looked over yer site: http://sites.google.com/site/poiswebsite

could you add to the list of "successful remedies" complete abstinence? and please include in that the use of 1) lucid dreaming to control dreams in order to prevent nocturnal emissions, and 2) in combination with a mild muscle relaxer, taken before sleep, that desensitizes and makes nocturnal emissions virtually 100% preventable.

This is the method I have used for half a decade and has a 99.98% (DAMN THAT .02%!!) success rate, and has enabled me to be symptom-free virtually every day of those 5 years. I think it's important that this is listed since, imho, it is the only 100% cure (yeah yeah not a cure but you know what i mean).

and btw realllly nice work on that site.... thats exactly what is needed... sry i havent checked it out earlier....

coming to this Naked Science Forum regularly is.... a difficult process for me, since i have zero hope a cure will ever be found. i apologize for not checking out YOUR site sooner.

zomg i found a discussion on POIS that Jim_B hasnt posted in yet:

http://forums.plentyoffish.com/13714168datingPostpage2.aspx

guy on a dating website wants some help lol.

[GoingCrazy]

coming to this Naked Science Forum regularly is.... a difficult process for me, since i have zero hope a cure will ever be found.

You'll be surprised