[janiv]

Hi Guys,

Just want to have your thought about something that I think is missing.
I believe that many of us started to take POIS more seriously since each of us understood he is not the only one on earth with such a disorder.

That means that each one of us has lot of medical information [Comprehensive Blood tests, sperm tests, allergy tests and etc.]

I'd say, what is missing is an integration of all that data - if we could do a data analysis of all that data -we might find some commonalities, I be live the answer is might be there;
what we do have now is individuals that kindly shares their medical tests data along the hundreds of pages of this forum. If we only could have a share point or shared excel document/ web document including all tests of each 1 of us - that could be a big step forward.

I would go further and say we could build a profile of each 1 of us. But let's start with integrating the medical data of each of us. That's lot of work that demands how to organize the file, adding into it all test in details, I won't get technically now how it should be looked, first let's have your feedbacks,

Wish you all health !

[lauracostis]

Demo,

I cant remember, I know we have talked about FMRI's, but has anyone taken an FMRI while in pois or out.

[JRD]

Has anybody here tried to masturbate several times in a row (i.e. 4 - 10 times in a few hours) and watched its effects or better - tried to masturbate as many times as possible per day and keep continuing in the following days?

Btw. an interesting article to read:
http://www.drlwilson.com/ARTICLES/MASTURBATION.htm [nofollow]

"Holding the mind in unhealthy thought patterns. This is a further problem with frequent masturbation in both men and women.  It is worse in women, in fact.  This problem simply means that stimulating the genital organs tends to cause a certain type of thinking and feeling that is generally harmful for a person.  Once in a while it is fine, but it is not healthful, overall, especially if it is a habit that one does daily or more often.  This applies to sexual relations also, along with pornography.
This is more complex topic that has to do with the type of energy that resides in the lower part of the body, as compared with the type of energies that reside in the upper part of one’s body.
The symptoms of this problem include difficulty concentrating, attention deficit or ADD, ADHD, irritability, superficiality in your thinking, lack of intelligence, lack of follow through ability, impaired school or work performance, and other difficulties in thinking clearly and forcefully."

[lauracostis]

Here is a new and interesting drug to look at, "Vinpocetine", it is a prescription drug in Europe marketed for cerebral vascular disease, but recently approved as a over the counter supplement marketed for cognitive enhancement in the United states and Canada.  It says it is a cerebral vascular dilator, increasing blood flow to the brain.  After our recent mixed success with xanthinol nicotinate and niacin, I started to look into drugs that might increase blood flow to the brain.  Unrelated to my search, I found a web page that referenced both vinpocetine and XN.

http://www.vinpocetine.com/how-can-vinpocetine-help-us.html


"In 1976 Vamosi and colleagues reported their favorable results comparing Vinpocetine with Xanthinol Nicotinate in treating 143 patients with various cerebrovascular diseases. They measured a large number of blood and cerebrospinal fluid variables before and after treatment, such as glucose, lactate, pyruvate, oxygen, pH, electrolyte levels, etc. They concluded from their study "…Though not all the changes are significant statistically, yet connected with each other they prove that Vinpocetine enhances both glycolytic and oxidative reactions of glucose breakdown in eNS [brain]. The changes in the concentration of K [potassium] and Mg [magnesium]. .. may be considered a sign of recovery of the energy metabolism of the nerve cells.…"1
Vamosi's study also demonstrated a superior clinical efficacy of Vinpocetine over Xanthinol Nicotinate."

This may lead to other drugs that may help us such as Vinpocetine or may just give us a better understanding of how Niacin containing compounds may be helping us, such as increasing cerebral blood flow.

[danny123]

I think I have POIS psychological effects but none of the physical effects of POIS. I also have a very adverse reaction to alcohol or drugs where I am psychologically damaged for months afterwards from only a few beers or even being in a room that has marijuwana smoke. after a long period of soberiety I have healed from previous alcohol/drug intake. It seems like I have a hyper sensitivity to anything that is mind altering including an orgasm. It can take me about 6 weeks after orgasm to be mentally sharp, relaxed, not anxious but confident but the side effect of abstaining from an orgasm is over confidence. I feel like I'm alternating between two worlds never knowing who I am. The person with POIS symptoms who takes life seriously and works really hard to get by or the recovered but over confident person. Does anyone else have a hyper sesitivity to alchol, fumes, or drug smoke and have POIS? I wish I knew why I am so super sensitive to anythig mind altering including an orgasim.

[daveman]

Here is a new and interesting drug to look at, "Vinpocetine", it is a prescription drug in Europe marketed for cerebral vascular disease, but recently approved as a over the counter supplement marketed for cognitive enhancement in the United states and Canada.  It says it is a cerebral vascular dilator, increasing blood flow to the brain.  After our recent mixed success with xanthinol nicotinate and niacin, I started to look into drugs that might increase blood flow to the brain.  Unrelated to my search, I found a web page that referenced both vinpocetine and XN.

http://www.vinpocetine.com/how-can-vinpocetine-help-us.html


"In 1976 Vamosi and colleagues reported their favorable results comparing Vinpocetine with Xanthinol Nicotinate in treating 143 patients with various cerebrovascular diseases. They measured a large number of blood and cerebrospinal fluid variables before and after treatment, such as glucose, lactate, pyruvate, oxygen, pH, electrolyte levels, etc. They concluded from their study "…Though not all the changes are significant statistically, yet connected with each other they prove that Vinpocetine enhances both glycolytic and oxidative reactions of glucose breakdown in eNS [brain]. The changes in the concentration of K [potassium] and Mg [magnesium]. .. may be considered a sign of recovery of the energy metabolism of the nerve cells.…"1
Vamosi's study also demonstrated a superior clinical efficacy of Vinpocetine over Xanthinol Nicotinate."

This may lead to other drugs that may help us such as Vinpocetine or may just give us a better understanding of how Niacin containing compounds may be helping us, such as increasing cerebral blood flow.

This could be a good test to make to determine if it as a result of vasodilation in the brain or
some other effect like the building of missing components in important brain components like serotonine and dopamine et al. see: http://poiscenter.com/forums/index.php?topic=197.0

[daveman]

I think I have POIS psychological effects but none of the physical effects of POIS. I also have a very adverse reaction to alcohol or drugs where I am psychologically damaged for months afterwards from only a few beers or even being in a room that has marijuwana smoke. after a long period of soberiety I have healed from previous alcohol/drug intake. It seems like I have a hyper sensitivity to anything that is mind altering including an orgasm. It can take me about 6 weeks after orgasm to be mentally sharp, relaxed, not anxious but confident but the side effect of abstaining from an orgasm is over confidence. I feel like I'm alternating between two worlds never knowing who I am. The person with POIS symptoms who takes life seriously and works really hard to get by or the recovered but over confident person. Does anyone else have a hyper sesitivity to alchol, fumes, or drug smoke and have POIS? I wish I knew why I am so super sensitive to anythig mind altering including an orgasim.

Hey Danny123,

Over at reuniting.info they have a whole forum dedicated to addiction / withdrawl which even includes sex. You can probably get a lot of help over there.

[daveman]

Has anybody here tried to masturbate several times in a row (i.e. 4 - 10 times in a few hours) and watched its effects or better - tried to masturbate as many times as possible per day and keep continuing in the following days?

Are you kidding, if I have one "O" on each of two days in a row, I'm practically ready for the hospital.

If there's anyone here that can have several "O"s per day, I don't think it's POIS that they have.

[Habibou]

Hi Guys,

Just want to have your thought about something that I think is missing.
I believe that many of us started to take POIS more seriously since each of us understood he is not the only one on earth with such a disorder.

That means that each one of us has lot of medical information [Comprehensive Blood tests, sperm tests, allergy tests and etc.]

I'd say, what is missing is an integration of all that data - if we could do a data analysis of all that data -we might find some commonalities, I be live the answer is might be there;
what we do have now is individuals that kindly shares their medical tests data along the hundreds of pages of this forum. If we only could have a share point or shared excel document/ web document including all tests of each 1 of us - that could be a big step forward.

I would go further and say we could build a profile of each 1 of us. But let's start with integrating the medical data of each of us. That's lot of work that demands how to organize the file, adding into it all test in details, I won't get technically now how it should be looked, first let's have your feedbacks,

Wish you all health !

GREAT THAT SOMEONE THINKS THE SAME AS ME ! I already created a topic on the other forum, please post there to have more info : http://poiscenter.com/forums/index.php?topic=98.0

[JRD]

Are you kidding, if I have one "O" on each of two days in a row, I'm practically ready for the hospital.

If there's anyone here that can have several "O"s per day, I don't think it's POIS that they have.

As far as I know, most people have no physical abnormalities capable of explaining such a variety of symptoms and no diagnostic criteria has been constitued to prove this mystical illness. The only certain thing disproving the suspicion is not to have post-orgasmic complications and probably nobody like this has joined the discussion yet.

And I am curious what reaching several orgasms in a row (even if the first one or two brings up problems) looks like in your case or in case of somebody who has experimented this way.

[Starsky]

[/quote

Has anybody here tried to masturbate several times in a row (i.e. 4 - 10 times in a few hours) and watched its effects or better - tried to masturbate as many times as possible per day and keep continuing in the following days?

Are you kidding, if I have one "O" on each of two days in a row, I'm practically ready for the hospital.

If there's anyone here that can have several "O"s per day, I don't think it's POIS that they have.

Which hospital? Psychiatric? POIS is not a life threatening condition...

Has anybody here tried to masturbate several times in a row (i.e. 4 - 10 times in a few hours) and watched its effects or better - tried to masturbate as many times as possible per day and keep continuing in the following days?

Last week I tried to force as many ejacalutions as i could get on a day... 2days, 7 ejaculations... i would be normally sick after 2 but thanks to XN i was able to get to the point where i got dry ejaculations. I wasnt sick, i was just tired and really unmotivated. Was it POIS or was it a normal reaction to so many ejaculations?

[B_Daniel]

Here is a new and interesting drug to look at, "Vinpocetine", it is a prescription drug in Europe marketed for cerebral vascular disease, but recently approved as a over the counter supplement marketed for cognitive enhancement in the United states and Canada.  It says it is a cerebral vascular dilator, increasing blood flow to the brain.  After our recent mixed success with xanthinol nicotinate and niacin, I started to look into drugs that might increase blood flow to the brain.  Unrelated to my search, I found a web page that referenced both vinpocetine and XN.

http://www.vinpocetine.com/how-can-vinpocetine-help-us.html

Anyone want to try it and report back to the group?  It's relatively cheap ($13.99):
http://www.antiaging-systems.com/159-vinpocetine-intelectol

[Vincent M]

Which hospital? Psychiatric? POIS is not a life threatening condition...

I don't think there's enough data gathered to prove whether anyone has died from it yet. Before I found fenugreek I could barely leave my bed and I could forget about getting a job ever. I'm fairly certain that people have lost jobs and gone homeless from POIS...death could easily follow that.

Besides as we've seen there is a spectrum of the severity which POIS symptoms manifest themselves in different people. Who can say with all certainty that some of the earlier members who no longer post on our forums have not died from POIS?

[Quasar]

Here is a new and interesting drug to look at, "Vinpocetine", it is a prescription drug in Europe marketed for cerebral vascular disease, but recently approved as a over the counter supplement marketed for cognitive enhancement in the United states and Canada.  It says it is a cerebral vascular dilator, increasing blood flow to the brain.  After our recent mixed success with xanthinol nicotinate and niacin, I started to look into drugs that might increase blood flow to the brain.  Unrelated to my search, I found a web page that referenced both vinpocetine and XN.

http://www.vinpocetine.com/how-can-vinpocetine-help-us.html


"In 1976 Vamosi and colleagues reported their favorable results comparing Vinpocetine with Xanthinol Nicotinate in treating 143 patients with various cerebrovascular diseases. They measured a large number of blood and cerebrospinal fluid variables before and after treatment, such as glucose, lactate, pyruvate, oxygen, pH, electrolyte levels, etc. They concluded from their study "…Though not all the changes are significant statistically, yet connected with each other they prove that Vinpocetine enhances both glycolytic and oxidative reactions of glucose breakdown in eNS [brain]. The changes in the concentration of K [potassium] and Mg [magnesium]. .. may be considered a sign of recovery of the energy metabolism of the nerve cells.…"1
Vamosi's study also demonstrated a superior clinical efficacy of Vinpocetine over Xanthinol Nicotinate."

This may lead to other drugs that may help us such as Vinpocetine or may just give us a better understanding of how Niacin containing compounds may be helping us, such as increasing cerebral blood flow.

Lauracostis, really thanks for that. It goes in the same direction i've been thinking about (migraine/blood circulation/serotonin theory...)

Some replies ago i posted that the Niacin flush was caused by a release in peripheral serotonin, which causes a vasodilation in the body. The raised levels of peripheral serotonin inhibit the release of brain serotonin, so it prevents the contraction of brain blood vessels (serotonin inside the brain causes contraction).

So, Vinpocetine seems to work in a similar way as Niacin, but in a more active way. Maybe it's a little more aggressive than Niacin, but also more effective. It should be very interesting to try it!!

BTW, at last i've bough Niacin pills!! THis afternoon i'll try them and comment on how they've worked for me!

Another one i'd like to try is Pycnogenol:

In addition, the particular proanthocyanidins found in the propriety extract for maritime pine bark called Pycnogenol have been shown to optimize the production of nitric oxide in the artery walls so as to relax them and allow greater blood flow and reduced pressure.[23] Additionally, this same preparation, Pycnogenol, has been found to normalize platelet adhesion (aggregation) so as to facilitate normal blood flow.[24]

[Vincent M]

Are you kidding, if I have one "O" on each of two days in a row, I'm practically ready for the hospital.

If there's anyone here that can have several "O"s per day, I don't think it's POIS that they have.

I disagree with you here, Daveman. I am able to have multiple orgasms a day, but I am always in a constant state of POIS because of this. My major recent accomplishment has been being able to stay awake during the day and sleep at night, but I've only accomplished that with fenugreek. I'm still quite a ways off from being able to work. I suffer from almost every symptom that POIS sufferers have mentioned except for, perhaps, headaches.

In addition I wear a chastity device which I had to design myself since I don't have money to buy a real one and when I get an erection what are basically metal spikes drive into my penis causing enough pain to force me to stop the erection. I wear this device everyday now just so I can stay on a normal sleep schedule in hope that I'll one day be able work up enough energy and confidence to apply for some jobs.

Just because my sex drive is higher or the time between orgasm and when I'm able to ejaculate again is shorter than normal doesn't mean that my POIS symptoms are any less debilitating than yours.

I like you, Daveman, and I agree with many of your points. But I know you are wrong when you say that I don't have POIS, because I know I do. POIS is defined by debilitating symptoms that last for multiple days after orgasm. It takes me about a week after an orgasm before I feel able to get out of my bed and even have a normal conversation with one of my close friends or do any kind of physical labor. Until that point all I wanna do is lay in my bed and try to figure out a way to make the horrible pain go away.

I believe that this forum might prevent me from becoming homeless one day since my mom's not gonna be able to support me forever. So don't count me out. I understand you think I probably have sexual exhaustion and not POIS, but how can you say that when there is no precise definition of either that differentiates POIS from SE? If you believe that SE is a milder version of POIS then I have POIS. Not SE.

[daveman]

Has anybody here tried to masturbate several times in a row (i.e. 4 - 10 times in a few hours) and watched its effects or better - tried to masturbate as many times as possible per day and keep continuing in the following days?

Are you kidding, if I have one "O" on each of two days in a row, I'm practically ready for the hospital.

If there's anyone here that can have several "O"s per day, I don't think it's POIS that they have.

Which hospital? Psychiatric? POIS is not a life threatening condition...

Yes psychiatric! I did it once and thought I was going out of my mind. It was at night, perhaps a combination of panic atttack and a strong after POIS depression!

Not at all to laugh at. I hope that wasn't your intention!

[Vincent M]

Has anybody here tried to masturbate several times in a row (i.e. 4 - 10 times in a few hours) and watched its effects or better - tried to masturbate as many times as possible per day and keep continuing in the following days?

Yep I think when I tried doing that I masturbated like 10 times in one day. My POIS symptoms just became so severe that I could barely walk because my knees and tendons felt so inflamed and all I could do was lie down and think about ways to kill myself. Even lying down didn't take away all the pain since my face was so inflamed or something it felt like my skin was barely attached to my face and my eyes felt like they were on fire if I tried to open them. Oh and my intestines were probly inflamed too because my belly ballooned to the point where it looked like I had a soccer ball stuffed in there even though normally I had a fairly visible abs. I remember I couldn't wear pants because my skin was so irritated.

[daveman]

Are you kidding, if I have one "O" on each of two days in a row, I'm practically ready for the hospital.

If there's anyone here that can have several "O"s per day, I don't think it's POIS that they have.

As far as I know, most people have no physical abnormalities capable of explaining such a variety of symptoms and no diagnostic criteria has been constitued to prove this mystical illness. The only certain thing disproving the suspicion is not to have post-orgasmic complications and probably nobody like this has joined the discussion yet.

And I am curious what reaching several orgasms in a row (even if the first one or two brings up problems) looks like in your case or in case of somebody who has experimented this way.

Are you saying JRD that POIS is a mystical illness? How many of you all agree with this!

We've spent too much time taking POIS out of some etheral space to have it put back into a fantasy category again.

[JRD]

Well, no satisfactory explanation has been found, so it is quite obvious for me, it is mystical in the same sense such as schizophrenia or depression - scientists and doctors claim they know a lot, but in fact, they only offer many speculative approaches with little to no effective help to their patients.

[Starsky]

Has anybody here tried to masturbate several times in a row (i.e. 4 - 10 times in a few hours) and watched its effects or better - tried to masturbate as many times as possible per day and keep continuing in the following days?

Are you kidding, if I have one "O" on each of two days in a row, I'm practically ready for the hospital.

If there's anyone here that can have several "O"s per day, I don't think it's POIS that they have.

Which hospital? Psychiatric? POIS is not a life threatening condition...

Yes psychiatric! I did it once and thought I was going out of my mind. It was at night, perhaps a combination of panic atttack and a strong after POIS depression!

Not at all to laugh at. I hope that wasn't your intention!

Sorry. I was ironic... But I asked myself what kind of help we could get in a hospital? Intravenous fenugreek?

You were going out of mind because of POIS or because of things they gave you? I think if someone is lucky, will get just a hand full of benzodiazepines, if not.... they can make you really bad with neuroleptics.