[nathan123]

nathan123
That is wonderful news for you that Flunarizine hydrochloride is working well for you. With your doctor, did you describe migraines as one of your main symptoms? I don't get migraines at all. I do get pressure headaches but it is only during the warmer more humid months of the year, otherwise I get brain fog all year around. I did not find much info on Flunarizine hydrochloride and post coital headache on the www. 
Are you experiencing any side effects since taking it?

nathan, as regards your point C. Neem has anti-parasite + anti-bacterial properties I thought. The fact that you feel better skipping meals can also fit in with this. I get the same effect, eating less I handle pois/cfs better, skipping the evening meal and I have a more refreshing night's sleep. Many CFS sufferers report the same. I have had a few bowel/fecal pathology tests and showed up with parasites + numerous bad bacterial overgrowths. I am have had a number of treatments over the past 4 yrs and my pois symptoms are not as severe, but I still have them. I am going to do a follow up path test in a few weeks to see how things are. I am not saying this is the cause of pois, but maybe a contributing factor for some of us that puts extra load on the liver or absorption of nutrients or creation ofneurotransmitters, IDK.

I never told that I am suffering from Migraine with my doctor.  I explained my POIS symtoms with him which will trigger after an o.  And he mentions it as Post Coital illness syndrome and prescribed medicine.  It seems he knows more on this illness and treatment.  During my next visit, I will ask my doctor to post in this forum how I am getting success with this medicine and how POIS trigger after an o.  so that everyone including me get clarity . Presently there is no side effects after taking it. 

For me in POIS, i gets only cognitive symtoms.  My all cognitive symtoms has been reduced to an great extent so that this can be tolerable like a common headche / fever. Hopefully this small POIS effects will be reduced within next 3 months as per told by doctor. 
In google, there is no more information on Post coital illness as this name we call in our country and neighbouring country. 

[nathan123]

I have a confusion about whether I have POIS or Post Coital headche and for my condition doctor told that it is a Post Coital headche illness.  So, please explain me whether my problem is a POIS by seeing the following symtoms.  By Calcium Channel blocker, my POIS has clearing now, so I want to discuss with doctor on POIS vs Post Coital headche illness. 

When I am in POIS, I have the following symtoms,

a) Brain fog, low concentration, low memory, Fatigue, burning in head, confusion
b) Depression
c) Burning eyes,
d) feeling imbalance in head
e) Abnormal breathing
f) High Anxiery
g) Difficult to have eye contact
h) Stammerting at the great extent
i) Imbalance in sleep and excessive dreaming
j) Emotional imbalance
h) Very rare occasion I also had throat infection.
and I don't get any flu and physical symtoms.
These symtoms will be there for atleast one months and very difficult to remove when attacked.  Upto last 2 months, my symtoms as explained above.  Please clarifiy to me.

[kurtosis]

I have a confusion about whether I have POIS or Post Coital headche and for my condition doctor told that it is a Post Coital headche illness.  So, please explain me whether my problem is a POIS by seeing the following symtoms.  By Calcium Channel blocker, my POIS has clearing now, so I want to discuss with doctor on POIS vs Post Coital headche illness. 

When I am in POIS, I have the following symtoms,

a) Brain fog, low concentration, low memory, Fatigue, burning in head, confusion
b) Depression
c) Burning eyes,
d) feeling imbalance in head
e) Abnormal breathing
f) High Anxiery
g) Difficult to have eye contact
h) Stammerting at the great extent
i) Imbalance in sleep and excessive dreaming
j) Emotional imbalance
h) Very rare occasion I also had throat infection.
and I don't get any flu and physical symtoms.
These symtoms will be there for atleast one months and very difficult to remove when attacked.  Upto last 2 months, my symtoms as explained above.  Please clarifiy to me.

It does seem like your doctor is just giving this a label because the symptoms aren't primarily about headaches, although I've had some POIS-related headaches they're actually rare.
However, that doesn't mean that flunarizine won't be effective in treating symptoms but I'd be worried about taking calcium blockers indefinitely.

[B_Daniel]

Nathan, is your question whether u have pois or pois coital headache syndrome?

You clearly have pois as we define it. Does the real definition of poist coital headach syndrome overlap with Pois? the answer to that is maybe but probably not. Does your doctor's definition of post coital headaches overlap with pois? He seems to think so. But it doesnt matter what he calls pois as long as he understands it and knows how to fix it. Does he understand it and know how to fix it? Who knows Nathan.

Regardless, as kurtosis points out the calcium blocker is not healthy to take long term. At some point, even if it's is working, u will need to find an alternative. I suggest starting with a supplement that decreases histamine and increases methylation.

[daveshan]

Hi, my name is Dave and this is my problem with what I believe is P.O.I.S.




-The Problem-
*Masturbation and only masturbation causes negative effects on my body and mind that can last indefinitely.
*Sex and nocturnal emissions do no harm.  It’s only masturbation.
*No doctor nor therapists has been able to help.


 -Body Problems-
*Decrease in muscle mass.
*Feeling of a lack of connection between parts of the body, as if tendons and ligaments are weak.
*Joints are tense and weak, especially knees.
*Sweat is more profuse.
*Penis feels stiff and tense, but is flaccid and soft.
*Breathing isn’t labored or strained, but it is harder breath.
*Slight increase in blood pressure.
*Blood vessels feel constricted.


-Mental Problems-
*Harder to focus
*Harder to stay awake
*Learned skills that require coordination diminish in quality.



-The Only Way I’m Able to Fix the Problem-
*Achieving a full and solid erection using only arousing thoughts and memories as stimulation.
*Cannot use any other stimulation.  Not pictures, sounds, touch, not even muscle contractions.  ONLY thoughts and memories.
*All problems with masturbation remain until and only until a full erection is achieved just from thought.
*While the basic problems that occur from masturbation go away, the parts of body and factors of the mind that were affected don’t return to previous levels (i.e., muscle mass returns somewhat but not completely, learned skills don’t get completely re-learned,…).  More erections purely from thoughts and memories help though.


-Difficulties with Erections caused only from Thought-
*Takes LOTS of time and effort.
*Comparable to practicing to run a mile when being out of shape.  At first, arousing thoughts can only give me a small tingle.  Then a little more the next day.  Then a little more a day or two after that.  Then a little more the next day…  so on and so forth until I get a full erection.  Then I won’t be able to get another erection for a day or so.  After a while, though, I’m able to have a full erection, purely from thoughts or memories with ease.
*However, if I masturbate again, everything goes back to zero and it’s as though I have to ‘practice for the mile’ all over again from square one.
*Also after masturbating, whatever thoughts and memories helped me get an erection before typically won’t help again.


-Being well-hydrated seems to help

-Eating pizza seems to help


-Info about my health-
*I don’t do drugs, although I was over-prescribed with behavior meds as a child.
*Physically active
*In all around good health
*Not a very active sex life.
*I’ve had an MRI and nothing unusual was found.

[John21 (OP)]

Nathan, I hope the medication continues to work for you. The histamine theory does sound plausable to me, it would explain how anti-inflammatory foods help reduce POIS for me. I am interested learning any way that high histamine can be reduced, I'll have to read up on calcium channel blockers.  I have also noticed recently that reducing food intake makes me feel better. It seems all too easy to eat too much, so I am making a point of trying to eat only what I need to so that the body has less work to do digesting. Digestion takes a whole lot of energy, and reducing the workload on the body might free it to work on repair, like an energy budget.

[Kingkong]

Just an update,

It is after 14 days start taking the calcium channel blockers (Flunarizine hydrochloride). I have an o at the 10th day, 11th day, and 14th day (twice).  My all cognitive symptoms such as lack of mental clarity, Stammering, anxiety, difficulty in thinking, burning sensation are reduced extremely and presently running without Herbal life and Neem. Only taking the above medicine.  The only problem remaining is excess dreaming at night and abnormal breathing.

Hence, it is working superbly.  Now my social life has changing, I am calm, cool and started to present papers & seminars in office. My life totally changed.   I met doctor yesterday and he told that it is only 20 to 30% of recovery and it takes around 3 months for complete recovery from this.  But I am in a feeling that I have recovered 70% as my cognitive symptoms disappeared. 

Waiting in next 3 months, how my life will be after complete recovery.

Request you to consult your doctor and as per his guidance take the above mentioned tablet. Its working.  Initially I shared only herbal remedies with temprovery sucess and without scientific reason.  Finally I have shared my success with scientific medicine with reason for clear of POIS. 

My next proposed findings with the help of this forum and my doctor:
a) I want to know how the Testerone replacement theraphy reduce symptoms (cured)for demo and other person in this forum.  (What is the link between TRT and Calcium Channel Blocker)
b) What is the link between Niacin and Calcium Channel Blocker.
c) How Neem has stopped my POIS for 2 months and then how low diet food (without morning breakfast and dinner  and Herbal life) has helped me in some how temprovery blocking of POIS.

Please try this medicine for atleast 20 days (under guidance of doctor) and see the results.   Please don't expect result in first week. 

Hi Natan, I'm taking flunarizine for two day now. Even if I'm taking citalopram since 6 years for anxiety, my doctor don't find any problem for me taking flunarizine. Here in Canada, flunarizine is not use anymore but still available. So, i'll wait ( we'll wait, my wife and me) and I will give news after two weeks.

[jferr]

Wow how much worse my POIS has gotten in the past couple of months. I have muscle tremors, I cant think well at all, Trouble breathing correctly, Fatigue, Trouble sleeping/getting up, Neuro problems so bad that I have trouble controlling facial expressions, Etc.. 25 years old just getting into my family's business and I am not me. I have tried so many things .... I really need help ....

[gondal4]

i dont understand what you people mean by "flush".explain in simple terms

[CertainlyPOIS]

i dont understand what you people mean by "flush".explain in simple terms

First of all you get the flush from using niacin and not from pois.

The flush occurs after about 30 mins after using niacin on an empty stomach. the flush involves redding of the skin and very intense itching sensation you would not be able to stop scratching your body for about 30 mins.  And then the sensation subsides.
It is generally considered safe.  Dont be scared of it.

[CertainlyPOIS]

That is the only way that

Just an update,

It is after 14 days start taking the calcium channel blockers (Flunarizine hydrochloride). I have an o at the 10th day, 11th day, and 14th day (twice).  My all cognitive symptoms such as lack of mental clarity, Stammering, anxiety, difficulty in thinking, burning sensation are reduced extremely and presently running without Herbal life and Neem. Only taking the above medicine.  The only problem remaining is excess dreaming at night and abnormal breathing.

Hence, it is working superbly.  Now my social life has changing, I am calm, cool and started to present papers & seminars in office. My life totally changed.   I met doctor yesterday and he told that it is only 20 to 30% of recovery and it takes around 3 months for complete recovery from this.  But I am in a feeling that I have recovered 70% as my cognitive symptoms disappeared. 

Waiting in next 3 months, how my life will be after complete recovery.

Request you to consult your doctor and as per his guidance take the above mentioned tablet. Its working.  Initially I shared only herbal remedies with temprovery sucess and without scientific reason.  Finally I have shared my success with scientific medicine with reason for clear of POIS. 

My next proposed findings with the help of this forum and my doctor:
a) I want to know how the Testerone replacement theraphy reduce symptoms (cured)for demo and other person in this forum.  (What is the link between TRT and Calcium Channel Blocker)
b) What is the link between Niacin and Calcium Channel Blocker.
c) How Neem has stopped my POIS for 2 months and then how low diet food (without morning breakfast and dinner  and Herbal life) has helped me in some how temprovery blocking of POIS.

Please try this medicine for atleast 20 days (under guidance of doctor) and see the results.   Please don't expect result in first week. 

Hi Natan, I'm taking flunarizine for two day now. Even if I'm taking citalopram since 6 years for anxiety, my doctor don't find any problem for me taking flunarizine. Here in Canada, flunarizine is not use anymore but still available. So, i'll wait ( we'll wait, my wife and me) and I will give news after two weeks.

nice.

[JACKMAN]

yo guys, im 21 and i have  symptoms you guys have described.

i feel really weak, agitated and nauseous, also my penis feels tight and my prostrate feels to be fighting the flow of semen, (this could be physical) after ejaculation but for from what ive read i dont suffer as bad as some of you, my symptoms usually last about 15-20mins but in that time i feel like death, so of course has depressed me for a while, and it is quite hard to explain to partners why you cant go through with it avoiding sexual contact altogether,
when i have ejaculated with partners i have felt really cold towards them and do not want to be touched. sometimes i feel that my symptoms dont last long enough for me to worry as much but people dont know how we feel so cant understand.

[JACKMAN]

yo guys, im 21 and i have  symptoms you guys have described.

i feel really weak, agitated and nauseous, also my penis feels tight and my prostrate feels to be fighting the flow of semen, (this could be physical) after ejaculation but for from what ive read i dont suffer as bad as some of you, my symptoms usually last about 15-20mins but in that time i feel like death, so of course has depressed me for a while, and it is quite hard to explain to partners why you cant go through with it avoiding sexual contact altogether,
when i have ejaculated with partners i have felt really cold towards them and do not want to be touched. sometimes i feel that my symptoms dont last long enough for me to worry as much but people dont know how we feel so cant understand.

must add that when i have nighttime emissions i dont get any of these symptoms.

[Prancer]

yo guys, im 21 and i have  symptoms you guys have described.

i feel really weak, agitated and nauseous, also my penis feels tight and my prostrate feels to be fighting the flow of semen, (this could be physical) after ejaculation but for from what ive read i dont suffer as bad as some of you, my symptoms usually last about 15-20mins but in that time i feel like death, so of course has depressed me for a while, and it is quite hard to explain to partners why you cant go through with it avoiding sexual contact altogether,
when i have ejaculated with partners i have felt really cold towards them and do not want to be touched. sometimes i feel that my symptoms dont last long enough for me to worry as much but people dont know how we feel so cant understand.

Hey jackman, welcome! Really interesting to hear that your symptoms only last 15-20 minutes.

If you have any questions, feel free to ask one of us and we will try to get your answer for you.

[John21 (OP)]

If POIS is a histamine problem I wonder if it might be possible to take an anti-histaime some time before and perhaps after sex to prevent the symptoms, without being on it full time. Has anyone experimented with anti-histamines besides nathan? I know the histamine theory has been kicked around for years, GoingCrazey had some success with Clairitin. Has anyone else benefited from anti-histamines besides Nathan and GC?

[Over it]

Surprise, surprise, the Doxycycline has not cured me. But the relief it gave me from symptoms was very real, until I copped a severe bout of POIS before I had even finished the second and final week of my perscription (go figure). I am very eager to hear more from user Coreman, particularily so after coming across a breif discussion about sustained, elevated prolactin levels in a post by user Mellivora in 2007 (see page 2 of this thread).

[CertainlyPOIS]

If POIS is a histamine problem I wonder if it might be possible to take an anti-histaime some time before and perhaps after sex to prevent the symptoms, without being on it full time. Has anyone experimented with anti-histamines besides nathan? I know the histamine theory has been kicked around for years, GoingCrazey had some success with Clairitin. Has anyone else benefited from anti-histamines besides Nathan and GC?

If you are going by kurtosis theory then normal antihistamines would not be enough because they dont cross BBB well and dont go after the histamine3 receptors which are connected to cognition problems.
You can try his proposed combination to deactivate histamine by increasing methylation.

[acronym]

If POIS is a histamine problem I wonder if it might be possible to take an anti-histaime some time before and perhaps after sex to prevent the symptoms, without being on it full time. Has anyone experimented with anti-histamines besides nathan? I know the histamine theory has been kicked around for years, GoingCrazey had some success with Clairitin. Has anyone else benefited from anti-histamines besides Nathan and GC?

If you are going by kurtosis theory then normal antihistamines would not be enough because they dont cross BBB well and dont go after the histamine3 receptors which are connected to cognition problems.
You can try his proposed combination to deactivate histamine by increasing methylation.

Its possible the methylation cylcle in us is not normal. It would be great if we could all do gene testing for this, but it is not cheap.
Here are a couple of links for those interested in methylation that may see something interesting in relation to their health. I know it was interesting for me because a number of liver supps and methylation supps I have taken have made me worse over the years. It can explain why for some of us why diet changes play a role in feeling better...but its tricky to 2nd guess.

http://www.mthfrsupport.com/1/post/2012/05/other-gene-mutations-that-must-be-addressed-before-starting-an-mthfr-protocol.html
http://www.heartfixer.com/AMRI-Nutrigenomics.htm

[GoingCrazy]

If POIS is a histamine problem I wonder if it might be possible to take an anti-histaime some time before and perhaps after sex to prevent the symptoms, without being on it full time. Has anyone experimented with anti-histamines besides nathan? I know the histamine theory has been kicked around for years, GoingCrazey had some success with Clairitin. Has anyone else benefited from anti-histamines besides Nathan and GC?

Yes, claritin did help me, I was definitely better taking claritin than nothing at all.  When I took claritin most and sometimes all of the mental symptoms were gone, but they were delayed for about a day, but that makes sense because I took a claritin 24hr.  So even after orgasm, and taking an antihistamine, the reaction still was occurring but I wouldn't feel it, and when the claritin stopped working I felt it.

I also wanted to note that after taking a heavy dose of aspirin for POIS I've had one of the worst episodes to date.  It is now day 4 and I still feel like I am in day 1, although it did offer relief when I first took it.  Aspirin's blood-thinning affect can last for a long time.

[GoingCrazy]

I was also thinking about trying a "mast cell stabilizer" it prevents histamine, prostaglandins and leukotrienes from being released by mast cells, instead of just an antihistamine.  Here is a link I found.

http://www.urticare.com/Treatments/Mast+Cell+Stabilisers.html

Imagine if the same applied to POIS; "An additional feature that has been noticed with Ketotifen is that in the vast majority of patients who have become asymptomatic on Ketotifen if the medication is continued for some 4 months or so, a significant proportion of patients remain well after that without any further treatment being required."

Tell me what you guys think.  I did notice they have some side effects, but I may still give them a try.

On second note after researching them some more they do seem a little extreme, for ketotifen you have to be on it for some months for it to work, it's also used for asthma patients.