[Gbolduev]

Acethylcholine  GABA balance is   adrenal  thyroid  balance,   copper zinc/     
One day  you will remember what I told you .  Make sure   to keep your  zinc  and thyroid up and your Gaba will be up and you wont have  acethylcholine overload.  But some people  have it  other way  around,  and in both cases,  you will  end up with  estrogen   dominance,  like you had,   high thyroid or low thyroid  equals  estrogen  dominance and POIS

[desperate man]

Acethylcholine  GABA balance is   adrenal  thyroid  balance,   copper zinc/     
One day  you will remember what I told you .  Make sure   to keep your  zinc  and thyroid up and your Gaba will be up and you wont have  acethylcholine overload.  But some people  have it  other way  around,  and in both cases,  you will  end up with  estrogen   dominance,  like you had,   high thyroid or low thyroid  equals  estrogen  dominance and POIS

TRUE! I have choline deficiency. Hypothyroid and adrenal fatigue will be enough to give you POIS.
I'm like 6 days ejaculation free and just started having symptoms of POIS without even doing anything at all.
Now I really really feel that my POIS is tied together with adrenal fatigue and it will have more impact on me if I masturbate in the morning but not in the evening.

Why? Most likely because my cortisol is low in the morning and high in the evening. It's the blood sugar imbalance + low cortisol induced by AF that triggers this nightmare but the funny thing is I can get rid of this feeling if I go eat something that elevates my blood sugar and take a 30 minute nap on the bed.

If I ejaculate it will take me 4-5 days to recover.Having a hard time thinking right now but it also could be brain inflammation from heavy metal toxicity that over-excites the neurons and that leads to AF and POIS.

Is there any of you who haven't started masturbating to porn in their teens? Why can't I see 50 or 60 years old POIS patients around?
I'm guessing that porn does permanent damage to the developing brain and will alter firing rate in those WHO ARE GENETICALLY PREDISPOSED TO IT.

[johanstefansson]

Nathan,

If you read my previous posts that is what  I wrote exactly, about acethycholine and gaba imbalance and  POIS as an effect of post marijuana  smoking.

I have never smoked anything in my entire life and I have POIS.

[LAPOISSE2]

Hi All,

I had a 12 days vacation in a tropical country ; As I was in holiday, I O everyday ; Strangely, I felt great(maybe 20% of my usual POIS symtoms) ; what is interesting I spent two days in the mountains(2400m altitude) and my POIS symtoms came back. For me 4 explanations :
-No stress = less POIS ; in addition being in hollidays, we don't need to use our brain so POIS is less noticable
-Food was different : i ate a lot of fruit and raw food
-The climate has an important in POIS(not the first one too notice)..I would like to understand what in the climate has an influence inb biochemistry ; D vit ? What elses.
-O everyday allow me to remain reasonably high and not experience deep POIS symtoms(not the first one also to try this strategy)

Since I'm back, I stopped Sex and I slowly dive into POIS symtoms to reach a peak about 1 week after.

It's very similar to after drug usage crash ; It's like I was high for 10 days and now i've been down for a week.

I thought it could help.

[LAPOISSE2]

Hi, from the god sake POIS not bounce back even after one and half month and having an avg of three o's in a week. 
Today visited the doctor for further appointment had a discussion for 2 hours and I would like to explain the discussion as per with my doctor. 

In the earlier post, I posted only there was only numerological imbalance in me due to over masturbation resulted in POIS.  Today I asked in depth.  As per doctor for me, there was a over stimulation of acetylcholine parasympathetic nervous system.  Due to there was a imbalance in CNS and over production of acetycholine leading to imbalance in brain chemistry.  Further, there was also imbalance in digestive system and function of liver.  That's why he has prescribed me four different varieties (one for CNS, one for digestion, one for parasite and another for stress and another for increasing vitamin C i.e. amla juice) and also suggested to follow one diet system for one month so that brain chemeistry should be normal. 

After following the medicine and diet, brain chemistry i.e. ratio of various hormones and CNS came normal.  He warned if any time continues Over masturbation for one month, again POIS will come.   

To confirm this, pl check google for symtoms of over stimulation of acetylcholine parasympathetic nervous system and also for symtoms of high acetycholine.  Also for masturbation and acetycholine parasympathetic nervous system.

Also I found one of the symtoms of high acetycholine is flu like symtoms that we have in POIS. 

Further he also mentioned that there is no medicine to restore this in allopathy medicine.  for this the only solution through herbal.

Problem is symtoms of excess or deficience acetilcholine or pretty much the same ; My doc prescribed me two drugs to try : it's deanol and sulbutiamine ; they apparently both stimulates cholinergic activity ; As I fell like sh1t anyways, i'll give a try...i should be fixed about wich side I am.

[nathan123]

Nathan,

If you read my previous posts that is what  I wrote exactly, about acethycholine and gaba imbalance and  POIS as an effect of post marijuana  smoking.

I have never smoked anything in my entire life and I have POIS.

Look, i don't the raionale on smoking an acethycholine imbalance.  But over masturbation or over sex leads to high acethycholine imbalance.  For me the problem was come from over masturbation and leading to over stimulation of acethycholine parasthetic nervous system and resulting in over production of sex hormones i.e. acethycholine leading to imbalance in other hormones in the brain.  I never spoken on smoke.  To confirm my view you just search in google for excesssive masturbation and acethycholine. 

[fornicationDENIED2]

Hi All,

I had a 12 days vacation in a tropical country ; As I was in holiday, I O everyday ; Strangely, I felt great(maybe 20% of my usual POIS symtoms) ; what is interesting I spent two days in the mountains(2400m altitude) and my POIS symtoms came back. For me 4 explanations :
-No stress = less POIS ; in addition being in hollidays, we don't need to use our brain so POIS is less noticable
-Food was different : i ate a lot of fruit and raw food
-The climate has an important in POIS(not the first one too notice)..I would like to understand what in the climate has an influence inb biochemistry ; D vit ? What elses.
-O everyday allow me to remain reasonably high and not experience deep POIS symtoms(not the first one also to try this strategy)

Since I'm back, I stopped Sex and I slowly dive into POIS symtoms to reach a peak about 1 week after.

It's very similar to after drug usage crash ; It's like I was high for 10 days and now i've been down for a week.

I thought it could help.

Folic acid deficiency can lead to decreased levels of serotonin in the brain. Fruits and vegetables that contain folic acid can help to boost serotonin levels. There is an inverse, antagonistic relationship between acetycholine (ACh) and serotonin (SE) in the brain. In other words as the quantity of one increases, the quantity of the other decreases.

Acetylcholine excess includes all my symptoms, brain fog, nightmares, diarrhea, flu like symptoms, and maybe decreased levels in the brain of the neurotransmitters: serotonin, norepinephrine,  and dopamine . But why we have an imbalance? I don't buy the over masturbation (because if it were true POIS would be an epidemic), it must be something, else, a mutation in our DNA causing  acetylcholinesterase (Acetylcholine breaking enzyme) deficiency?

http://mindrenewal.us/page13.html

[fornicationDENIED2]

I do not fully understand this balancing/lowering of Acetylcholine. Where can I find detailed information about this?

[Vincent M]

Do anyone of you get facial swelling,puffiness after ejaculation? Also,do you have low sodium levels?
Seem to be silly questions but I need you to answer them.

I get noticeable facial swelling and face and scalp irritation within an hour after an ejac. When I first began developing pois my friends commented that I appeared to be getting fatter, even though I was actually not gaining any weight - it's just that my face seemed fatter due to the inflammation/swelling. Also my muscles around my face seemed to slacken slightly causing some of the flesh to sag lower on my face. Not sure about low sodium, but I once had a blood test that showed I was slightly low in potassium and the doc suggested I might need to add more salt to my diet. I feel slightly better after having a glass of salt water, but the effect is barely noticeable.

Saw palmetto and fenugreek+tea/garlic reduce a significant amount of the face swelling and irritation.

[Vincent M]

Huperzine is an acetylcholinesterase inhibitor and improves my cognition during pois after 2 days of 200 micrograms per day. There is some good lab evidence of its ability to improve cognition in alzheimer's patients. That's all I have to add about acetylcholine.

[CertainlyPOIS]

Everybody one of the rules of the forum is to not use adult language because of kids that come by the forum.

[B_Daniel]

Desperate, Some of the things youre saying resonate with my own experiences. For instance, i have weak adrenals. And, my blood-sugar is definitely tied to my pois. Even if im experiencing a fantastic day, and i go most the day without eating, my pois will come back, very strongly. I'll basically become a mute. And even if i eat a big meal, it's too late. My pois is there to stay. After times like these my pois will be bad another 2-4 days. Consequently, I never allow myself to get too hungry anymore.

 I'm not sure  I'm not sure whether morning Os or having an O on an empty stomach translate to worse pois, but ill try to pay attention to that in the future. Seems plausible.

Ive personally never had a negative sexual experience so i dont think ptsd plays a role w me.

My sodium is 138 within a 135 to 145 reference range, so low depending upon who u ask.

[meteo74]

Hi All

-for me if I smoke I well  get my hed lost(I dont smoke).
-mast. has powerfull pois than sex.

masturbation is the reason of pois.

[Gbolduev]

Nathan

 I am not talking about smoking anything/  I said   that  marijuana  inhibits acethylcholinesterase  which  increases  acethylcholine.  I also said that masturbation and excessive sex  will deplete zinc,    which  will lower your gaba  which will automatically  increase  acethylcholine  gaba balance and  make your thyroid low.  This is your case.  It is not like your replenished  zinc,  you just  induced  acethylcholine  with  your medicine, which  is not going to last,  especially  since you are having orgasms,  depleting zinc even more.  Vitamin  C  increases   iron which  decreases copper and  automatically increases zinc  relatively , but   in your case 3-4 orgasm a week is  insane. 

[Gbolduev]

zinc  and copper    control   gaba and  acethylcholinesterase/    There are no mutations, there is simply deficiencies.  You have to stay away from sex and  replenish   these metals,   including  iron manganese  copper and zinc , and all your enzymes will  work again.  Zinc increases gaba , lowers  acethylcholine for instance , if you have that imbalance/  POIS is caused by inflammation from  low testosterone levels, since  your horomones are not balanced. 

[johanstefansson]

Hi All,

I had a 12 days vacation in a tropical country ; As I was in holiday, I O everyday ; Strangely, I felt great(maybe 20% of my usual POIS symtoms)

I have had the same experience but I think the sunshine was what made me feel better.

[johanstefansson]

Since 1st of May I have abstrained from sex with my partner, taken niacin more often and kept a strict diet, making sure i always eat breakfast, lunch and dinner. Here´s what has has happened.

- improved sleep, quite better and more regular
- more nocturnal emissions, drastic increase
- less sex drive
- more calm and relaxed
- overall more healthy, no anxiety for quite some time.

[benvil]

Hello guys. Is it worth trying the recipe kurtosis made? I've tried Niacin and it works for me but I still am damaged a lot from POIS. Can the "recipe" help this and what is your experience when trying it?

[Vincent M]

Hello guys. Is it worth trying the recipe kurtosis made? I've tried Niacin and it works for me but I still am damaged a lot from POIS. Can the "recipe" help this and what is your experience when trying it?

A few others have seemed to have had some benefits from b-complex and the recipe. I took a highly bio-available b-complex for a while and had mild improvement in some physical pois symptoms. I think more of our members have had better improvements with fenugreek+garlic than b-complex.

[romies]

Hello guys. Is it worth trying the recipe kurtosis made? I've tried Niacin and it works for me but I still am damaged a lot from POIS. Can the "recipe" help this and what is your experience when trying it?

A genetic test, e.g. 23andme.com, will help you to identify which part of your pathways (methylation etc) may be inefficient. You can then adjust Kurtosis' regimen to fit your need.

I found his regime very helpful for me, with some small tweaks.