[CertainlyPOIS]

I was wondering if you guys can please Pm me the outside reasearch that you have done.  i want links, books. I am going to start doing some extensive reasearch and i want to know where to start and what to skip.
I will start with alcohol+weightgain+immunesystem.
alcohol and weight gain were the two main things that change in my life when i noticed full effects of pois.

[CertainlyPOIS]

MUST CHECK OUT/ 2ND TO THE LAST PARAGRAPH.
http://www.nutramed.com/immunology/mediators.htm, -
This website talks about cytokins and interlukins and how they affect thinking.

[demografx]

I had an orgasm 3 days ago and I catch a cold the day after... There is really something wrong with immune system.

B_Jim, in my earlier years of POIS, I was constantly getting colds the day after, until I learned to keep my physical and mental activity/output to a bare minimum. That worked for me very well. (But I became a zombie).

I agree, it always felt like orgasm immediately lowers the proper functioning of the immune system: a sudden and very strong feeling of susceptibility to colds and flu.

[demografx]

We exceeded the number of 300 [POIS] cases.

Great to hear!

[demografx]

I was wondering if you guys can please Pm me the outside reasearch that you have done.  i want links, books.

Doesn't the welcome-newcomer post contain all that?

[martin88]

Personally I rarely get flu, but have allergies. I had allergies before my first orgasm which could eventually cause a tendency to develop POIS (?)
The flu-like symptom described by some of you in POIS does not appply to me or I don't have enough experience with flu. I'd say I'm just very tired after a short effort in POIS.

Do you get flu the day after or immediately?
Bad sleep weakens the immune system and has often been reported in POIS.

I forgot to report that after a nocturnal emission I always have half sleep for the rest of the night with very pronounced racing mind, I can't relax.

[martin88]

Watson Pharmaceuticals
Our contact promised to write up a possible POIS study scenario and send it on to a company committee that meets several times a year for consideration.
I wrote again today asking when I can call to follow up with Watson to see what our status is.

Great efforts Demo, hope this will work!

Good to hear that you are still getting the better of POIS, Demo! My Fenugreek has all but killed the social anxiety component of POIS I used to suffer from.

I believe that POIS is a sliding scale, and potentially millions of people may suffer from a milder form of POIS which could also be treatable.

I think my sociability is not changed in POIS, but since my cognitive problems will eventually be noticed by people this is causing social anxiety.
Maybe we have excessive dopamine out of POIS and not enough in POIS, like hyperglycemia followed by hypoglycemia. Fenugreek is reducing dopamine..

I believe a lot of cases of depression can be undiagnosed POIS.

[mister_z]

I believe a lot of cases of depression can be undiagnosed POIS.

From what I have been reading so far, it would seem to me that starting at puberty the human brain is flooded with "random" spikes of hormones; which define our behavior for the rest of our lives. So, personally I believe ANYTHING that we do/experience from puberty until death is heavily influenced by our hormonal/neurotransmitter state.

[mister_z]

I was wondering and looking for a simple answer actually...

As far as blood pressure is concerned does dopamine lower or raise it?
How about serotonin? testosterone?

I have noticed that after orgasm when I dont get the shakiness, nausea, cold, sweats etc... I get irritable and eventually sad.
My father (after interrogation confessed that after orgasm he also feels sad)

Should I give SSRI (or SNRIs) a go? I tried Paxil a long time ago, gave me panic attacks so never finished the first 2 weeks of "adaptation". (same problem with imipramine)
The problem I have with SSRI/SNRI (and other psychoactive drugs) is the time they take to work and their addictive properties. I'm not sure I could be bothered to renew
prescriptions for such drugs.

I'd like to give testosterone patches a shot (even though it is my free testosterone that is low) just to briefly see how I feel on them. I wouldn't intend to stay on them for a long period also as I suspect that it would soon become useless as the testosterone would just get bound. Is there btw a proven way to unbind testosterone ?
I doubt my doctor would agree to give me testosterone even as a short trial because my free testosterone levels are indeed lower than normal range but not dramatically so; or should I insist ?

[nsf]

I have observed my blood pressure level goes up significantly in 24-hours after orgasm. It takes days, sometimes weeks, before feeling being back to normal. My BP readings goes beyond 150/90. Do anyone feel similar symptoms?

[demografx]

B_Jim, in my earlier years of POIS, I was constantly getting colds the day after, until I learned to keep my physical and mental activity/output to a bare minimum.

I agree. Many testimonies refers to "cold after sex". In fact, the  best thing to do is to sleep, if possible.

Yes, I agree! Sleep is the most effective tool. Naps, even for just a few minutes have often broken or at least reduced the POIS spell (hell!) for me!

[CertainlyPOIS]

I have observed my blood pressure level goes up significantly in 24-hours after orgasm. It takes days, sometimes weeks, before feeling being back to normal. My BP readings goes beyond 150/90. Do anyone feel similar symptoms?

that has happned to me once but i never checked after that.

[demografx]

I doubt my doctor would agree to give me testosterone even as a short trial because my free testosterone levels are indeed lower than normal range but not dramatically so; or should I insist ?

I insisted. Insisting worked.

I suspect that taking more T than necessary, i.e., going beyond normal range might be the trick for POIS (vs. for hypogonadism, the usual treatment application). It certainly was for me. Just my theory, though! Not proven! Caution please, and work with an open-minded endo!

Insisting on treatment (I emphatically said it was for POIS, and said it loud and clear as if POIS were a major worldwide illness : - ). And this was 7 years ago! I was desperate, after 30 years of POIS Agony/Life Destruction and then finding a highly regarded Czech sex researcher who thought testosterone was the key to POIS. Insisting was necessary before working with my endocrinologist. No need to insist now.

I don't trust most T-testing. Prior to my current endo, my tests were mostly done badly with GP's and urologists, including one test that classified me as a female and said my T was too high!! (There is no way that my first name is even close to a female name!)

I trust the testing now (which includes much repeat testing of not just T (incl free T and bioavailable T), but related hormones such as LH) And I very much trust my endo - who was and is open to POIS, a very important point - and the University lab, which has a strong reputation.

[demografx]

I believe a lot of cases of depression can be undiagnosed POIS.

I think goingcrazy would agree. I responded negatively to one of his posts about that, but maybe I was wrong.

[CertainlyPOIS]

I was wondering if you guys can please Pm me the outside reasearch that you have done.  i want links, books.

Doesn't the welcome-newcomer post contain all that?

It only contains what people have posted i want what hasnt been posted.

I want more material other than summaries.

[mister_z]

Anyone suggested starting a wiki yet?

[demografx]

http://en.wikipedia.org/wiki/Postorgasmic_illness_syndrome

[demografx]

CC, everything I know is posted. After 3 years, you think we've missed some major non-posted references? If so, where would we, or anyone, start to look?

[John21 (OP)]

nsf,
As I mentioned, temporary high blood pressure in the POIS state was a definite symptom for me, at least some of the times.

[demografx]

I'm not sure I can contribute intelligently to the BP discussion, since I'm on (very effective) blood pressure meds.