[Counterpoints]

Ive yet to try it prior to orgasm,
but Im thinking its not for me.

The most critical time to test these meds is prior to orgasm... I would do that before dismissing it.

I think about 2-3 hours before orgasm would be the best time to take the norethisterone.  Could take two tablets every hour for three hours preceding orgasm, and then two tablets one hour after.  (That *is* a reasonably large dose, and it's probably what I'd do for myself if I tried it again (after checking to see its reasonably safe), but you decide what's right for you.  The main point here, however, is the timing).

[CertainlyPOIS]

Horizon how many hrs did use it before orgasm.

it was 5 days after I took it (Norethisterone) 4x5mg.
On a second occasion I took 2x5mg about 24hrs after. no positive effects.

Ive yet to try it prior to orgasm,
but Im thinking its not for me.

I agree with counter point that you must use it before orgasm. I will do some reasearch on how quickly noriethisterone is absorbed by the body to determine best time to use it. 

from the artice i deduce since 10mg prevented pois for the patient and his recovery takes 3 days and  in my case it takes 7 days to recover,  i will try 20mg before orgasm. to prevent recurring symptoms i will use 5 mg for couple more days.   
I havnt tried this yet but hopefully i can try it in the future.
* before trying any drug make sure to consult your doctor.*

[pauliebaby61]

Since we are all axiously awaiting Dr. Waldingers treatment, I thought it might be interesting if we all shared our thoughts about what his cause/treatment will be. Here is my best shot:

After 19 yrs of this issue, and spending multiple thousands of $$ on 'cures' or seeing specialists and trying everything imaginable, such as: Ozone,Chelation, I.V. antibiotics, I.V. vitamins,Bio feedback, Rife,HGH, testosterone (cream,patch and injections),B12 shots,depression meds, diets,hydrocortisone, prednisone, vitamins,herbs,colonics,diflucan[for systemic yeast],I.V. hydrogen Peroxide,colloidal silver,I.V. C4, amalgan removal[teeth],assorted bloodwork, mri's, cat scans,etc...

I have concluded that this problem[in my case] is probably closely related to exhausted adrenal glands,which is called hypoadrenalism. The adrenal glands are responsible for our bodies handling stress. Sex, and O put a huge amt of stress on the adrenal glands. When they become exhausted we can no longer function. If your glands are not that bad, you come back quicker[a few days]. If your glands are real bad, it takes weeks or months to recover from O.
Adrenals make Testosterone and DHEA,as well as the vital cortico steriods your body need everyday for normal function.... This may explain low T levels for some of us pois sufferers. A classic symptom of low adrenal function is feeling exhausted even after a nights sleep, and feeling better after 8pm.
Do a google search about hypo-adrenalism, or low adrenal fuction symptoms. The symptoms are errily close to those of POIS.Fatigue, brain fog,muscular weakness,thirst, hypogycemia.The answer MAY be adrenal support. I have used hydrocortisone during pois periods, and although it does not make me all better, it does pull me out of it.
I am an unusual, multi-layerd case though, as I have been dealing with Lyme disease and systemic yeast for years.I may be just a weird case. Hope you all get relief soon. I cant wait for the Dr's findings! Thank you all for your efforts in this endevor.
If POIS was a 'chic' disease, im sure everyone in hollywood would be having fundraisers and be in Washington or on TV, rallying for our cause. Thanks to every one of you! Your experiences have given me comfort and hope that our answer is coming soon!!!

[GoingCrazy]

I've read about insomnia because the last few days prior to last night I was having trouble sleeping, my heart would race as if I was combating infection, I'd sweat.  It says that insomnia can cause sexual problems.  I was having trouble sleeping because I'm trying to get myself on a sleep schedule.  Everyday I go to bed before 10 and wake up at 9.  i feel really good right now.

[Vandemolen3]

I know that this discussed earlier, but has one of the new users experimented with Viagra? Viagra raises testosterone....

[Green]

Perhaps Dr Waldinger's study will help to answer. Was this treatment effective also for fatigue?

Unfortunately for me it doesn't help a great deal on the fatigue side of things, but for myalgia there is definetly a positive difference, it's certianlly more effective if taken before orgasm say 1/2 hour prior or so.

[Green]

Same with me.  However, looking at pornography can make things worse.  Also, if I get really close to orgasm, I often can't just stop everything and go back to normal.  I'll feel quite tense.  I don't think this is specific to POIS, I think this is normal.  This makes me think it would be hard to follow Marnia's (sex without orgasm) suggestions.

Quitting pornography altogether might sound a little brash, but this is what I've done. It's probably been a lot easier for me because my libido has been diminishing for years and now it's practically 0. As long as it's not built up like an anxiety it does reap positive benefits out of POIS, such as increased concentration, ability to persevere and lethargy is significantly reduced.

Stimulation for long periods of time prior to orgasm for me always leads to an Incomplete Orgasm and as a result another one usually follows after a day or so and then that's it... full blown POIS hits me like a falling anvil from above.

[Green]

Since we are all axiously awaiting Dr. Waldingers treatment, I thought it might be interesting if we all shared our thoughts about what his cause/treatment will be. Here is my best shot:

After 19 yrs of this issue, and spending multiple thousands of $$ on 'cures' or seeing specialists and trying everything imaginable, such as: Ozone,Chelation, I.V. antibiotics, I.V. vitamins,Bio feedback, Rife,HGH, testosterone (cream,patch and injections),B12 shots,depression meds, diets,hydrocortisone, prednisone, vitamins,herbs,colonics,diflucan[for systemic yeast],I.V. hydrogen Peroxide,colloidal silver,I.V. C4, amalgan removal[teeth],assorted bloodwork, mri's, cat scans,etc...

I have concluded that this problem[in my case] is probably closely related to exhausted adrenal glands,which is called hypoadrenalism. The adrenal glands are responsible for our bodies handling stress. Sex, and O put a huge amt of stress on the adrenal glands. When they become exhausted we can no longer function. If your glands are not that bad, you come back quicker[a few days]. If your glands are real bad, it takes weeks or months to recover from O.
Adrenals make Testosterone and DHEA,as well as the vital cortico steriods your body need everyday for normal function.... This may explain low T levels for some of us pois sufferers. A classic symptom of low adrenal function is feeling exhausted even after a nights sleep, and feeling better after 8pm.
Do a google search about hypo-adrenalism, or low adrenal fuction symptoms. The symptoms are errily close to those of POIS.Fatigue, brain fog,muscular weakness,thirst, hypogycemia.The answer MAY be adrenal support. I have used hydrocortisone during pois periods, and although it does not make me all better, it does pull me out of it.
I am an unusual, multi-layerd case though, as I have been dealing with Lyme disease and systemic yeast for years.I may be just a weird case. Hope you all get relief soon. I cant wait for the Dr's findings! Thank you all for your efforts in this endevor.
If POIS was a 'chic' disease, im sure everyone in hollywood would be having fundraisers and be in Washington or on TV, rallying for our cause. Thanks to every one of you! Your experiences have given me comfort and hope that our answer is coming soon!!!

MRI's, CT scans, Ultrasounds, Blood tests, Private consultations, Acupuncture, Prescription medicines, Herbs, Homeopathic medicines and flights abroad for consultations have all cost me somewhere between £10K-£15K in difficult times, my estimation would be somewhere near the latter.

The tests have provided me with some answers and I'm happy with the treatment I get for some other health problems I've got bar POIS, which is the big one.

Some of the Doctors I've met have a perception of me with an Illness that's all in my head therefore it won't show up on the tests, it's quite the opposite. Personally I don't really care if they sympathise with me or not, the reasons for spending this much time and resources is obviously for a cure or effective which they have yet to provide, as life with POIS is pretty unbearable, miserable, sedate and I'm never really able to live to the potential which feel I can seek and I am mostly doing the job which they are employed to do so, because after all medicine is not an exact science and should be treated as such, it's the Doctors who treat POIS like a work of fiction that really manage to piss me off, it makes an absolute mockery of my efforts to seek a livable life.

I've given up on speculating the origins of POIS, it just appears people can be suffering from POIS for more reasons than one, but there may be a major factor in all cases thats contributes mostly to the cause of POIS.

Just last week I had an ACTH stimulation test, which tests for the functioning of the adrenal glands, hopefully when I get the results for this it'll clear up if adrenal fatigue has any play.

On a side note, it's been a pretty good day today, just gone a month since last POIS, I've been eating healthily as possible (low carbs/candida diet) exercise when I can and today I managed to successfully work on my car and fit the big brake conversion to my car which has been sitting around for a year  [B)] cue aching back  [xx(]

[Vandemolen3]

Since we are all axiously awaiting Dr. Waldingers treatment, I thought it might be interesting if we all shared our thoughts about what his cause/treatment will be. Here is my best shot:

After 19 yrs of this issue, and spending multiple thousands of $$ on 'cures' or seeing specialists and trying everything imaginable, such as: Ozone,Chelation, I.V. antibiotics, I.V. vitamins,Bio feedback, Rife,HGH, testosterone (cream,patch and injections),B12 shots,depression meds, diets,hydrocortisone, prednisone, vitamins,herbs,colonics,diflucan[for systemic yeast],I.V. hydrogen Peroxide,colloidal silver,I.V. C4, amalgan removal[teeth],assorted bloodwork, mri's, cat scans,etc...

I have concluded that this problem[in my case] is probably closely related to exhausted adrenal glands,which is called hypoadrenalism. The adrenal glands are responsible for our bodies handling stress. Sex, and O put a huge amt of stress on the adrenal glands. When they become exhausted we can no longer function. If your glands are not that bad, you come back quicker[a few days]. If your glands are real bad, it takes weeks or months to recover from O.
Adrenals make Testosterone and DHEA,as well as the vital cortico steriods your body need everyday for normal function.... This may explain low T levels for some of us pois sufferers. A classic symptom of low adrenal function is feeling exhausted even after a nights sleep, and feeling better after 8pm.
Do a google search about hypo-adrenalism, or low adrenal fuction symptoms. The symptoms are errily close to those of POIS.Fatigue, brain fog,muscular weakness,thirst, hypogycemia.The answer MAY be adrenal support. I have used hydrocortisone during pois periods, and although it does not make me all better, it does pull me out of it.
I am an unusual, multi-layerd case though, as I have been dealing with Lyme disease and systemic yeast for years.I may be just a weird case. Hope you all get relief soon. I cant wait for the Dr's findings! Thank you all for your efforts in this endevor.
If POIS was a 'chic' disease, im sure everyone in hollywood would be having fundraisers and be in Washington or on TV, rallying for our cause. Thanks to every one of you! Your experiences have given me comfort and hope that our answer is coming soon!!!

When I showed the results of my bloodtest on a Dutch hormon forum they said maybe there is something wrong with my adrenal glands. The moderator said that alternative doctors give hydrocortisone for it.

[Vandemolen3]

Just last week I had an ACTH stimulation test, which tests for the functioning of the adrenal glands, hopefully when I get the results for this it'll clear up if adrenal fatigue has any play.

Interesting. Let us know what the results are. If they find a shortage of cortisol after the test maybe others have a disorder on the adrenal glands too.

[Vandemolen3]

There are 2 major disorders of adrenal glands: Dissease of Adison and Cushing's syndrome. I don't think POIS-patiensts have Cushing because you have to see this on your side:



See my earlier post about adrenal glands.

Stress might be a factor. The famous Britisch writer Jane Austen died because of the dissaese of Adison. That's a dissease when the drenal cortex doesn't produce enough cortisol and aldosterone. She died in the 19th century, so no worries. Nowadays that can't cure Adison, but they have a treatment. Adison is rare, 120 per million people.
During a stressful situation into the adrenal glands normally cortisol, which enables the body to deal with that situation. In people with Addison's disease can be very serious stressful situations lead to a crisis of Addison and a shock.

With POIS you don't get a shock. But an O might be a stressfull situation for the body. So I am in for the cortisol theory. Does someone know which vitamins/pills you can use for a shortage of cortisol? Something you can buy without perscription. We all have too experiment a bit. Offcourse we have to be carefull. I ordered Fenugreek and Mecuna Pruriens.

P.S. Or is the opposite with POIS: drenal cortex  makes too much cortisol after an O?

[Counterpoints]

There are 2 major disorders of adrenal glands: Disease of Adison and Cushing's syndrome. I don't think POIS-patiensts have Cushing because you have to see this on your side

You don't need stretch-marks to have Cushings... it's just a symptom.  But if POIS people have hypercortisolism (my own urine tests have been high in cortisol), it does not seem to have a typical clinical manifestation of Cushing's.

[demografx]

 full blown POIS hits me like a falling anvil from above.

I love it! Best POIS description yet!!  []

[demografx]

I just found this article :
http://www.digitaljournal.com/article/286390#tab=comments&sc=&local=
Not sure it's serious.

I always think there is a little  part of truth in concept of "adrenal fatigue", even if some charlatans are abusing of it to sell useless supplements.

--

Pauliebaby61 : I agree with you.

B_Jim, perhaps that's why low-dose stimulants (as well as testosterone) seem to help my POIS so much.

[demografx]

pauliebaby61, many thanks for sharing your 19 years' accumulated wisdom! Painful trial and error, I'm sure!

[demografx]

While in a mood of gratitude, I'd like to once again acknowledge "neilep" (aka Neil) of The Naked Scientists/Naked Science Forum for his unflagging support of this thread since Day One!

Many thanks, Neil, for helping us make this thread at the very least a place for us all to lessen our POIS symptoms simply by sharing them with one another!

A manly xoxo to you!

[Vandemolen3]

There are 2 major disorders of adrenal glands: Disease of Adison and Cushing's syndrome. I don't think POIS-patiensts have Cushing because you have to see this on your side

You don't need stretch-marks to have Cushings... it's just a symptom.  But if POIS people have hypercortisolism (my own urine tests have been high in cortisol), it does not seem to have a typical clinical manifestation of Cushing's.

That's true.

And with Adison 92% of the suffers have Hyperpigmentation (a discoloration of the hands/ palms).

About a few weeks I will ask my familydoctor to send me too a endocrinologist. So he can check my cortisol. Last time I asked for a bloodtest for cortisol and other hormons. But the urologist didn't put cortisol on the list. And maybe he van do an ACTH test. In the meantime I hope that Green can tell us his result of his test.

[Vandemolen3]

Found some information about how to prevent UTI's (a few POIS-suffers have them). D-mannose is 50 times more effective than cranberries.

[Vandemolen3]

B-Jim, in the watching porn-theory the testosterone of POIS-sufferers must be high and the cortisol low. But most of us who had their testosterone checked have a low level. The low cortisol can be right.

So is L-Carnite good or bad to take in your opinion?

Hartproblems? Demo is still alive. Haha.
But if they find a cure for POIS this might not happen.

[Vandemolen3]

Haha I've got a lot of vitaminboxes too. And two of them (Fenugreek and Mecuna Pruriens) are unopened.
I've to still use Vitamin D because of my low level. I take 3 a day, 1 more than adviced. I've got magnesium too. I stopped using it because it gave me problems in the stomach (diarrhea). I will try it in the evening again.