[demografx]

Habibou, very well said!!!

[Quasar]

Put your shame in a bag and ask it (as I did and many others !)  [] it could make your shape better soon, do not miss this opportunity...

Thanks Habibou. I'm quite a shy guy, but I'll try to do it!

[Quasar]

I've got a question: Has anyone tried the standard procedure for semen allergy? I mean, the procedure they use to treat women for allergy of their men. Check this:

"At the University of Cincinnati, we treat semen allergy by desensitizing women to their sexual partner's semen with injections similar to regular allergy shots. We take ejaculate from the woman's sexual partner and separate the large and small proteins. The woman is skin tested to these proteins to determine which ones she react to. She is then desensitized over several hours to the proteins she reacted to in the skin test. The injections are given every 10 to 15 minutes at increasing concentrations. After the desensitization has been completed, ejaculate is instilled into the woman's vagina. If she has no symptoms, then the treatment has been successful.

It is believed that desensitization induces tolerance to one or more proteins, similar to how standard allergy injections work. We've had over 95 percent success with this treatment, but it's a laborious and costly process and it's hard to get insurance to cover it.

Some clinicians have tried to desensitize women using whole seminal fluid. They dilute the semen and gradually instill increasing concentrations of seminal fluid in the woman's vagina over time. There are several reports of this treatment being successful, but we have not found this treatment to be uniformly successful. Treatments used to treat seasonal allergies, such cromolyn sodium and oral antihistamines, have not been helpful, either."

Does Dr.Waldinger check for specific proteins?

[victor.kons]

Did she ever explain why she thinks XN will work she is the doctor she prolly has the best theory.

CCconfucius, I'm just echo-ing / adding on to your question above

Victor - Does Dr. Bruslenko speak English? 

It would be interesting to get a more detailed explanation from her of how she arrived at her Niacin theory, and also, given that she hit the nail on the head, perhaps she has her own theory on exactly WHAT pois is.  I'm especially blown away by the timing of her diagnosis with you - because she recommended Niacin to you even BEFORE Dr. Waldinger's auto-immune theory was published.  These were the 'dark ages' in my mind, when the leading theory on POIS was a hormone deficiency.  We've come a long way. 

Also, I wonder if she's read Dr. Waldinger's papers.  And I bet she'd be interested to learn that there's a forum of 300 people who suffer from POIS and a few of us are beginning to benefit from her treatment.  Perhaps even she'd be a candidate for the NORD research fund.

Have you seen her over the last few weeks and discussed any of these things with her yourself?  What is her specialty as well, I forgot what you told us

As far as I know she doesn't speak English and she don't know how to use computer, at least one year ago she didn't know.

I'm not sure about what was her theory, or whether she had a strong theory about POIS at all. Remember that her primary concern was to help me with my edema, not with POIS. POIS just was on her way and she needed to neutralize it somehow to have her treatment work on me. I didn't communicate with her for more then year after that, because the treatment of edema was over and thats it. But I think it would be great to invite and have a "cup of coffee" with her now.

Victor

[B_Daniel]

As far as I know she doesn't speak English and she don't know how to use computer, at least one year ago she didn't know.

I'm not sure about what was her theory, or whether she had a strong theory about POIS at all. Remember that her primary concern was to help me with my edema, not with POIS. POIS just was on her way and she needed to neutralize it somehow to have her treatment work on me. I didn't communicate with her for more then year after that, because the treatment of edema was over and thats it. But I think it would be great to invite and have a "cup of coffee" with her now.

Victor

It's ultimately up to you, Victor - but I personally think that'd be both a nice and potentially helpful (for our understanding of POIS) thing to do!  The financially backwards part about being a good doctor is that you lose your patient (and revenue source) as soon as you cure them.  maybe that's why my doctors have been so incompetent...

So do we have a POIS award lying around somewhere that we could hand over to Victor to present to Olga   []  I say that really only half-joking as she really does deserve some recognition from us.

[victor.kons]

Niacin Acid Tablets Report #5.

Yesterday I've tried to experiment with the dose of Niacin Acid used by jivetalk. I took 300mg in Niacin Acid tablets. And I had a very good experience.

Last time I'm working pretty hard - 15 hours a day, and last days I felt pretty bad, my heart started going down because of tiredness. After taking 300mg Niacin Tablets I felt rise of my strength, my heart started working good again and I finished important milestone yesterday in my work after having an O. Also I had pleasant feeling in my head. This time there were not any negative feelings from stomach or liver. So maybe I have started to adapt to Niacin Acid tablets somehow.

After taking 300mg of Niacin Acid I felt flush in 5 minutes and in an hour the flush was pretty strong, but this time it was even pleasant. My face was red, but I didn't feel any discomfort. I had an O in an hour after taking the tablets. I didn't feel any POIS symptoms neither yesterday, nor today in the morning. So, this time niacin acid tablets was as good as XN injections for me.

I'm going to continue taking niacin acid tablets several times more to check whether this result will be stable.

Victor

[jivetalk]

If you will now excuse me, I am going to make some 'I LOVE B3' Tshirts to wear around. I think some of you here also made some promises about putting up posters of a certain Guy and his CAT  []

That's hilarious!  First of all, I'd love an I heart B3 or maybe even a B3 is my Homeboy t-shirt.  Second, it'd be a bit cruel to have Demo hang up a picture of a banned former-member of the forum.  Victor, do you have a cat??  Maybe a picture of Victor would be a good compromise!  []

B_Daniel,

Hahaha..I was really only joking about the T-Shirts Great to hear you're fond of the idea though..
 

[jivetalk]

If you will now excuse me, I am going to make some 'I LOVE B3' Tshirts to wear around. I think some of you here also made some promises about putting up posters of a certain Guy and his CAT  []

That's hilarious!  First of all, I'd love an I heart B3 or maybe even a B3 is my Homeboy t-shirt.  Second, it'd be a bit cruel to have Demo hang up a picture of a banned former-member of the forum.  Victor, do you have a cat??  Maybe a picture of Victor would be a good compromise!  []

Unfortunately, due to forum space considerations, I had to merge the two (sorry).

Demo.......That is GOLD!

[jivetalk]

Niacin Acid Tablets Report #5.

Yesterday I've tried to experiment with the dose of Niacin Acid used by jivetalk. I took 300mg in Niacin Acid tablets. And I had a very good experience.

Last time I'm working pretty hard - 15 hours a day, and last days I felt pretty bad, my heart started going down because of tiredness. After taking 300mg Niacin Tablets I felt rise of my strength, my heart started working good again and I finished important milestone yesterday in my work after having an O. Also I had pleasant feeling in my head. This time there were not any negative feelings from stomach or liver. So maybe I have started to adapt to Niacin Acid tablets somehow.

After taking 300mg of Niacin Acid I felt flush in 5 minutes and in an hour the flush was pretty strong, but this time it was even pleasant. My face was red, but I didn't feel any discomfort. I had an O in an hour after taking the tablets. I didn't feel any POIS symptoms neither yesterday, nor today in the morning. So, this time niacin acid tablets was as good as XN injections for me.

I'm going to continue taking niacin acid tablets several times more to check whether this result will be stable.

Victor

Victor, Thank you very much for your continued experimentation and reports - I look forward to more of them. I am very Glad to hear that the 300mg of Niacin is almost as good or even the same as a XN injection. I'm going to place an order for some Xan-Pro Tablets soon to see if they are the same/better/worse than Niacin tablets.

I am VERY interested to see and hear about other people's experience with Niacin also - But please adhere to Victor's previous warnings.

[demografx]

Niacin Acid Tablets Report #5.

Yesterday I've tried to experiment with the dose of Niacin Acid used by jivetalk. I took 300mg in Niacin Acid tablets. And I had a very good experience.

Last time I'm working pretty hard - 15 hours a day, and last days I felt pretty bad, my heart started going down because of tiredness. After taking 300mg Niacin Tablets I felt rise of my strength, my heart started working good again and I finished important milestone yesterday in my work after having an O. Also I had pleasant feeling in my head. This time there were not any negative feelings from stomach or liver. So maybe I have started to adapt to Niacin Acid tablets somehow.

After taking 300mg of Niacin Acid I felt flush in 5 minutes and in an hour the flush was pretty strong, but this time it was even pleasant. My face was red, but I didn't feel any discomfort. I had an O in an hour after taking the tablets. I didn't feel any POIS symptoms neither yesterday, nor today in the morning. So, this time niacin acid tablets was as good as XN injections for me.

I'm going to continue taking niacin acid tablets several times more to check whether this result will be stable.

Victor

Victor, Thank you very much for your continued experimentation and reports - I look forward to more of them. I am very Glad to hear that the 300mg of Niacin is almost as good or even the same as a XN injection. I'm going to place an order for some Xan-Pro Tablets soon to see if they are the same/better/worse than Niacin tablets.

I am VERY interested to see and hear about other people's experience with Niacin also - But please adhere to Victor's previous warnings.

Yes, jivetalk, I agree.

Thank you, Victor, for sharing your experiences, insight and cautionary warnings about Niacin!

[B_Daniel]

I took 3 Xan-Pro tablets (450mg of XN) last night and after a mild flush for 20 mins I had an O.  My POIS today is sub 20% for sure!  Success!  I woke up this morning at 6:30am and had trouble going back to sleep until 8am.  On a POIS day, I wouldve slept til 1pm no problem.  I'll write a follow-up post later to let ya'll know if my pois symptoms creep back later today or not.

[B_Daniel]

I have a personal question.  I would love to get some feedback/understanding of this:

So I only realized I had POIS about 3 months ago.  Before that, I hated the fact that I could never think properly, that I was so moody, and that i was always tongue-tied - but that being said I just thought that that was ME.  When i first found this site I wend cold turkey from sexual activity.  haha I wouldn't even turn on my computer   Within 3 days the brain fog melted and I was a half-normal person.  Within 7 or 8 days, I would wake up in the morning completely wired - like I was on a drug.  I thought I was the smartest human being on the planet and there was nothing I couldn't do.  I became so witty and having conversations with people became so easy and going out was so much fun.  I could see through other people's lies and at work I could perform mathematical calculations in my head with no problem. etc, etc... 

Fast forward 3 months later, I typically go 5 days between O's now.  The POIS thick, impermeable brain fog melts away after day 2ish, but even by the 5th day I don't feel ANY better than day 2!  I'm a somewhat normal person again, but absolutely no superman.  It's like I'm in a constant state of 10% pois. 

(A few weeks ago I tried to break this and I went 2 weeks No "O".  It didn't do it.  That being said, i think it was one of those rare times I was in a pois funk, and having the O at the end of the 2 weeks got me out of it.  These "funks" btw aren't that rare with me.  I might get 1 in every 8 O's.)

Does anyone have any insight into what's going on with me?

The only explanation that I can think of to all this is that the 1st time I went w no sexual activity for a week and I felt like superman, my load was so FULL that I constantly was fighting the urge to O.  I don't get that anymore.  After day 3 the urges mostly take a backseat in my life now.  I take Saw Palmetto which reduces my urge - perhaps thats a bit of an explanation.

So my main question is, do any of you still feel like Superman when you're out of POIS?  Do I have hope that that can be my norm?

[Vincent M]

I also get that superhuman feeling while out of POIS sometimes. I used to orgasm about 3 to 5 times a day and if I went 2 days without an orgasm I'd feel normal, but on day 4 or 5 I'd feel revved up, my thoughts came very quickly and clearly, my physical strength increased dramatically, less social anxiety, super pain tolerance, etc. But once I got to that point it is impossible for me to resist any sexual urge and the only time I did go farther than 5 days the superhuman feeling wore off the next day and I merely felt normal. I haven't tried going that long without an orgasm for probly a year though so I don't know if I would still get that reaction.

[FinalPanic]

In reference to the above considerations - I have had pretty obvious POIS symptoms for best part of 28 years - it can be variable but all the feelings are identifiable as regularly discussed on here. My situation has improved with a healthier lifestyle but it is still far from perfect - just more manageable. I had often considered that I had been somehow afflicted by something that was causing a lot of fatigue in general and having an O simply drained the final energy remaining leading to a rapid downward spiral, from which recovery was a slow process - the depletion effectively leading to the POIS effect (I had considered the virus angle). It has been a very isolating and distressing time - it feels like the most stupid condition to have and I have been continually told by Dr's that I suffer from anxiety and so on (not so sure now). After orgasm I feel really great - wanting more - it takes about half an hour for the POIS to manifest - usually feeling uncomfortably hot (no temperature increase though - checked for that) and agitated with a strange scratchy headache and painful eye-sockets, then I get very down at the symptoms leading to a feeling of wanting to withdraw and be left alone, conversation feels like I have had too much to drink in a room full of teetotalers - all so unnerving. It makes me feel stupid and like I am living life through treacle (the brain fog I guess). Can this really be an allergic reaction - I suppose it can. I too have had days of abstinence and feeling empowered - almost elated - had occurred to me that maybe that was just a 'normal' feeling for most people, one that I rarely get to experience. I do seem to have variable amounts of fatigue - I can wake up more tired than when I go to bed sometimes - almost POIS like - all so confusing.


Enough of that - I have had a reply from Dr. Goldmeier:

"The psychologists I work with are doing neuropsychiatric testing to see if we can pick up objective evidence of poor brain function post orgasm compared to well time.
 
The immunologists are looking at semen allergy- but they are only seeing patients v slowly
 
If you want to come to see me- please let me have your name, dob and address"


I now just have to get motivated - will do my best as this in not exactly a local call for me and I am misunderstood at home (not believed).

[FinalPanic]

I am sure that this has been asked before - but it is hard to work through 100's of posts to find out. The allergy hypothesis is looking quite popular - it was even reported in last months Fortean Times magazine, it is good to see the coverage. What I am trying to get straight in my mind is when does the reaction take place - we obviously carry our semen around day-in day-out with no obvious issues. Is there some point of contact with the body that triggers this off. I know that I can be bought to the point of 'O' and the stop right before the actual event (big self-control required here) but still with semen being released - but there is no POIS afterwards. Carry on through and the symptoms will hit. I still think it possible the 'hit' from the orgasm can still be somehow responsible (like the mother of all hangovers) - any thoughts? Or am I way behind the curve on this?

I still find that a couple of Nytol help the next night.

[B_Daniel]

I am sure that this has been asked before - but it is hard to work through 100's of posts to find out. The allergy hypothesis is looking quite popular - it was even reported in last months Fortean Times magazine, it is good to see the coverage. What I am trying to get straight in my mind is when does the reaction take place - we obviously carry our semen around day-in day-out with no obvious issues. Is there some point of contact with the body that triggers this off. I know that I can be bought to the point of 'O' and the stop right before the actual event (big self-control required here) but still with semen being released - but there is no POIS afterwards. Carry on through and the symptoms will hit. I still think it possible the 'hit' from the orgasm can still be somehow responsible (like the mother of all hangovers) - any thoughts? Or am I way behind the curve on this?

I still find that a couple of Nytol help the next night.

Yes, FinalPanic, I asked this same question a few months back.   Basically, what I asked, is why when I play with myself (but don't get the big "O") I can still get fluid through the Urethra, but it doesn't bring on the full POIS force?  I was almost trying to prove that it is NOT an allergic reaction.

The response was from Guthrie. It was a great response so I paste it here for you:

I think we should distinguish between three different potential allergens: 1) sperm, 2) ejaculate-semen, 3) pre-ejaculate fluid.

So, when you masturbate, while stopping before ejaculation, pre-ejaculate (3) flows through your urethra, but semen (2) does not flow through your urethra.

We know that some people develop a POIS episode just from 3, without the occurrence of 1 or 2.  And, for instance, in Demo's case, he still has POIS symptoms after getting rid of 1, while 2 and 3 remain for him.  

Thus, ... we should ... take into account and distinguish the various elements that can potentially be contributing to an auto-immune reaction.

To rephrase part of what Guthrie wrote, some of us get POIS from the pre-cum AND the seminal fluid.  Some of us just get it from the seminal fluid.


I'll answer your other questions more specifically.

Quote:
I still think it possible the 'hit' from the orgasm can still be somehow responsible (like the mother of all hangovers) - any thoughts?

Yes - that is somewhat possible.  It's possible that the dopamine rush you got from the "O" is so intense, that similat to the after effect of a hardcore drug, you have depleted your seratonine and you get POIS.  However this has been disproved by night emissions.  Some ppl can have a Night Emission, and then wake up in the morning with full throttle POIS, although they got no pleasure out of it.  They didn't get the dopamine rush, but they did get the POIS.  You can test this on yourself by having an "O" and release all pressure on yourself as you "O".  It won't feel great, and you'll get full POIS.

Quote:
What I am trying to get straight in my mind is when does the reaction take place?

My rudimentary understanding is that when POISers have an "O", the allergic reaction begins when the seminal fluid hits the Urethra wall, the Vas Deferens, or somewhere else - as long as the seminal fluid passes the testes/blood barrier, we can then have caused the allergic reaction and the POIS chain of events can begin.  So at the point of the "O" is definitely WHEN.  That's pretty much agreed upon.  It's the HOW and WHERE that comprise most of the mystery.

Hopefully that answers your question.

[B_Daniel]

I want to be selfish and get back to my question regarding never feeling like Superman anymore.

So I have a feeling that if I masturbated twice a day for a week straight, and started this biofeedback mechanism cycle that my body always THOUGHT that I was going to "O" again soon, and then I went cold turkey from sexual activity for a week, I think that I would fill up to the point of pain, and I would feel like Superman again. But that's such a painful/uncomfortable/unsustainable state for me to be in.  If this is true, I find it unfortunate that I can only be 100% when I'm in pain.

Do other people agree/disagree with this fullness theory of mine?   Has this issue been broached before?

So if this new theory is valid, I now look at this Saw Palmetto that I've been taking for 2 months now.  It shrinks my prostate and reduces the amount of fluid in me (or so it feels like).  I always thought it was a godsend - my urges are reduced and I can go longer btwn "O"s.  But given my new thought process on this, I'm now beginning to think that it does me more harm than good, as it helps keep me in a constant state of 10-20% POIS.  To all those on a prostate medication like Flomax or Avodart - can you attest that you also don't feel like Superman on your non-POIS days bc you're never actually completely full?

Demo - your T replacement - you mentioned once before that that helps you rejuvenate more rapidly.  Does it also fill you up so that you're uncomfortably full and your mind is 100%??

What I'm getting at is I need to find a way to fill myself up and feel like Superman again.  Not that I would do it all the time, but I would like to have the ability/option to do it.  Even if it's uncomfortable, there are times when a lot is demanded from me at work or school and i can't just feel half-normal and get by. 

[pois_pois_go_away]

Hi guys. I've been a lurker on this forum for a loooong time, checking in occasionally to see what progress may have been made. Sorry I have not contributed to the forum in that time but work, family, and other things have just kept me too busy.

I would tell all the details of my story but it's pretty much been heard before here many times. This thing has plagued my life and is, as you all know, a major curse and a cruel, cruel joke. Like many here, it lasts for a good 5 days with me and hence, I abstain for weeks and even months or else risk my job anything else having to do with being a normal, productive human being. It's a total panic, and I go from intelligent, dynamic superman to a worthless, shriveled shell of a human being who doesn't want to face anyone or anything until the horror passes.

Needless to say this is a huge hit with my wife, who loves sex and deserves the best. Thank GOD she's incredibly understanding, never makes me feel bad about it, and we just both want to work to find a solution. But now I just wanted to throw in my 2 cents and state for the record that although I greatly appreciate the work that's been done on the study and allergy theory, I'm not buying it for one single minute. I know this thing better than the back of my hand (no pun intended), we've been "friends" now for many years.

I just know, intuitively, beyond any "facts" that what I experience is nothing like an allergic reaction. It's more like being impaled by Kryptonite. It's like my entire physical, mental and spiritual beings DIE. It's more than any flu-like symptoms, more than any allergic reaction, and more than anything that can even be described with mere words. This much I know: THERE'S MORE TO IT than what's being concluded here.

I wish I could contribute something more but I'm afraid that's it. Thanks for listening...

[CertainlyPOIS]

I want to be selfish and get back to my question regarding never feeling like Superman anymore.

So I have a feeling that if I masturbated twice a day for a week straight, and started this biofeedback mechanism cycle that my body always THOUGHT that I was going to "O" again soon, and then I went cold turkey from sexual activity for a week, I think that I would fill up to the point of pain, and I would feel like Superman again. But that's such a painful/uncomfortable/unsustainable state for me to be in.  If this is true, I find it unfortunate that I can only be 100% when I'm in pain.

Do other people agree/disagree with this fullness theory of mine?   Has this issue been broached before?

So if this new theory is valid, I now look at this Saw Palmetto that I've been taking for 2 months now.  It shrinks my prostate and reduces the amount of fluid in me (or so it feels like).  I always thought it was a godsend - my urges are reduced and I can go longer btwn "O"s.  But given my new thought process on this, I'm now beginning to think that it does me more harm than good, as it helps keep me in a constant state of 10-20% POIS.  To all those on a prostate medication like Flomax or Avodart - can you attest that you also don't feel like Superman on your non-POIS days bc you're never actually completely full?

Demo - your T replacement - you mentioned once before that that helps you rejuvenate more rapidly.  Does it also fill you up so that you're uncomfortably full and your mind is 100%??

What I'm getting at is I need to find a way to fill myself up and feel like Superman again.  Not that I would do it all the time, but I would like to have the ability/option to do it.  Even if it's uncomfortable, there are times when a lot is demanded from me at work or school and i can't just feel half-normal and get by. 

I used to get superhuman feeling on consistent basis and with that came extremely full testicles that hurted when water from shower it.
I dont get extremely full testicles anymore, and that stoped around the moment i tried dr lins product and dhea.  But when i do get a chance to heal it is a hit and miss with superhuman feeling but i do get superhuman feeling without full testicles.  So i dont think it has anything to do with full testicles. 


But your experience with not healing all the way even after abstaining for a long time is the same dilemma i face alot now.   
my theories;
not getting enough sleep during recovery week,
food allergy
sex dreams ( dreams about sex give me pois symptoms)
all that superhumanfeeling has taxed the body
the scariest of all,so much pois is starting affect the brain even outside of pois.
 

[Animus]

Hi Folks,
I've been working on some graphs and just posted them up on the Theoretical discussion thread (page 4!)of the new forum. Please have a looksee and comment. This was based on a very interesting article ( forwarded to me by lauracostis) which showed a relationship between ejaculation, and a period of 7 day semen regeneration. 
This was a scientific study, and could be a clue linking semen regeneration to POIS.
The work is theoretical, so please take it with a grain of salt! I made the graphs, and they can be modified or revised... Hope it generates some discussion.
thanks