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Post Orgasmic Illness Syndrome (POIS)

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8880 on: 18/08/2010 19:55:45 »
Quote from: reuniting on 18/08/2010 19:34:40

My site has a lot of visitors with various post-orgasmic complaints, although its focus is different (sexual relationships). I'm therefore always interested in the experiences of people struggling with POIS.

I know there's a belief that a pill will cure POIS, but it's actually looking like the situation is more complex than that. While we're waiting for science to figure it out, I'd just like to report on a behavioral approach that might offer comfort for some of you.

I know intimate relationships can be fear-producing when severe post-orgasmic symptoms will inevitably follow orgasm. Just keep in mind that many lovers experience milder forms of neurochemical shifts and related mood and perception changes after orgasm, too. Here's an account of a very sexually active woman (28) who decided to play around with the concept of sex play without orgasm. It might offer you another way of coping. http://www.reuniting.info/node/4466

As tribal, pair-bonding primates, we humans get a lot of rewards from friendly interaction, whether with a lover or other companions (pets can help too). The latest research on this point shows that having a mate reduces cortisol levels during stress. http://scienceblog.com/37587/marriage-and-committed-romance-reduce-stress-related-hormone-production/ I share this because I suspect that one way to improve neurochemical balance, and reduce symptoms, is to increase the degree of connection with others.

Intriguingly, the ancient Chinese sexologists observed that "frequent sex with occasional ejaculation is less depleting than occasional sex with habitual ejaculation." It may be that frequent affection with virtually no orgasm is an ideal path for those whose brains are very sensitive to the neurochemical changes after orgasm.



Reuniting, thank you so much for that wonderful post!! I sincerely hope that this will open a (continued) dialogue here at the forum about some immediate non-chemical ways to combat POIS, either as standalone experiments - or in combination with the chemical treatments that we have all been putting our hopes in.

Two is better than one, I say!

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8881 on: 18/08/2010 20:10:13 »

We also have "Reuniting"'s article links on our POIS Information Website. Her recently published book below covers quite a bit of ground on POIS:



Thanks again, "reuniting"!
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Offline Vandemolen3

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8882 on: 18/08/2010 20:15:28 »
Quote from: B_Jim on 18/08/2010 20:06:11
Vandemolen3:
Low vitamin-D = Low testosterone !

http://www.ncbi.nlm.nih.gov/pubmed/20050857

Reuniting : thank you for article.
It's clear that social and love behaviour increase release of oxytocin, causing a regulation of cortisol.
Thanks for the link.

It's true: my testosterone is also on the low side (11). Not too low.
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Offline Green

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8883 on: 18/08/2010 20:17:23 »
Quote from: Vandemolen3 on 18/08/2010 15:30:54

No this all there was on the form.


VitD: I will call my familydoctor when the result is final.
Testosterone: 6-12 is normal/ on the lower side
A familydoctor will not intervene my himself when the TT is 11. Maybe I have to ask him myself for a test treatment. Or do you know if there 's a vitamin/ pills/ food diet you can buy to bring Testosterone up?


Diet, Stresses, Lifestyle, Sleep, Exercise, Nutrition all have a significant bearing on testosterone levels.

Living with POIS is a MEGA stressor, I struggle mentally quite a bit both in and out of POIS, so even if there is no direct link for testosterone reduction for POIS suffers, indirectly it must have some sort of significance.

Vitamin D3 has a significant impact on total testosterone [1]http://news.bbc.co.uk/1/hi/health/8493042.stm and overall wellbeing, but from my experience, this sentiment isn't shared by the doctors I've consulted in the past. I'm deficient in D3 and soon as I get some of these other blood tests out of the way I'm going to try my hand at mega doses of D3 (5000IU<d3<10000IU superficial doses (400IU what was recommended by my doctor) hasn't worked in my favour to increase my levels and on the surface, vitamin d toxicity is easily recognisable.

My argument for trying out mega doses is because one of my colleagues also has a deficiency her levels were slightly below mine and she qualifies for 50000IU injections, weekly till her levels fall into a suitable area in the range.

Converse with your doc to discuss options!

[/quote]
Quote from: demografx on 18/08/2010 17:49:11
POIS turns up in the strangest places!
http://itsonlyfashionblog.com/2010/08/17/its-a-mens-sweater-i-dont-care/

lol, see first paragraph.

Demo congrats!!! You've inadvertently found the first case of POIS in a non biological being :P Maybe the owner of the sweater passed on the POIS to it :P
« Last Edit: 18/08/2010 20:20:03 by green »
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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8884 on: 18/08/2010 20:21:25 »
Quote from: reuniting on 18/08/2010 19:34:40

I know intimate relationships can be fear-producing when severe post-orgasmic symptoms will inevitably follow orgasm. Just keep in mind that many lovers experience milder forms of neurochemical shifts and related mood and perception changes after orgasm, too. Here's an account of a very sexually active woman (28) who decided to play around with the concept of sex play without orgasm. It might offer you another way of coping. http://www.reuniting.info/node/4466


I'm glad you said this because a number of us here have complained about POIS turning off female partners - because they might expect orgasmic sex and we're afraid of it!

But if this very sexual woman described above is happy to experiment, why not our wives or dating partners?

We don't even need to bring up the fact that we have POIS! (Besides, few people really "get it" when we do tell them!!)

Just tell your girlfriend or wife that this way might be more exciting!

Just another experimental thought!
« Last Edit: 18/08/2010 20:42:10 by demografx »
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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8885 on: 18/08/2010 20:28:43 »
Quote from: demografx on 18/08/2010 17:49:11

POIS turns up in the strangest places!
http://itsonlyfashionblog.com/2010/08/17/its-a-mens-sweater-i-dont-care/

lol, see first paragraph.

Quote from: green on 18/08/2010 20:17:23

Demo congrats!!! You've inadvertently found the first case of POIS in a non biological being :P Maybe the owner of the sweater passed on the POIS to it :P


 [;D] [;D] [;D]
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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8886 on: 18/08/2010 21:04:07 »
Quote from: demografx on 11/08/2010 17:27:48

Hi everyone. Should I do this? Please let me know! (This is from
The Spoof Magazine
writer)

Hey, [demografx], I was thinking: Would you be willing to be the subject of a formal interview?  I would publish it in The Spoof Magazine, which is free form. I always conduct interviews via email, so there is never any question as to the accuracy of quotes. I would ask for a signed release, and offer you the right of final approval before publication. I own all my work published on thespoof.com, and would of course grant you license to do whatever you'd wish with it, including unlimited license to publish for profit. Let me know and we'll discuss in greater detail, OK? Thanks.


I've decided not to do the interview with The Spoof Magazine.

Many thanks, everyone, for your input, I really appreciated it!!
« Last Edit: 18/08/2010 21:06:03 by demografx »
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Offline Green

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8887 on: 18/08/2010 21:19:45 »
Quote from: reuniting on 18/08/2010 19:34:40
My site has a lot of visitors with various post-orgasmic complaints, although its focus is different (sexual relationships). I'm therefore always interested in the experiences of people struggling with POIS.

I know there's a belief that a pill will cure POIS, but it's actually looking like the situation is more complex than that. While we're waiting for science to figure it out, I'd just like to report on a behavioral approach that might offer comfort for some of you.

I know intimate relationships can be fear-producing when severe post-orgasmic symptoms will inevitably follow orgasm. Just keep in mind that many lovers experience milder forms of neurochemical shifts and related mood and perception changes after orgasm, too. Here's an account of a very sexually active woman (28) who decided to play around with the concept of sex play without orgasm. It might offer you another way of coping. http://www.reuniting.info/node/4466

As tribal, pair-bonding primates, we humans get a lot of rewards from friendly interaction, whether with a lover or other companions (pets can help too). The latest research on this point shows that having a mate reduces cortisol levels during stress. http://scienceblog.com/37587/marriage-and-committed-romance-reduce-stress-related-hormone-production/ I share this because I suspect that one way to improve neurochemical balance, and reduce symptoms, is to increase the degree of connection with others.

Intriguingly, the ancient Chinese sexologists observed that "frequent sex with occasional ejaculation is less depleting than occasional sex with habitual ejaculation." It may be that frequent affection with virtually no orgasm is an ideal path for those whose brains are very sensitive to the neurochemical changes after orgasm.

This is it mate.

Human beings are sexual beings.

The only coping strategy I've had to POIS has been abstinence, this was difficult at the age of 12-16 and I would go just about life in a debilitated fashion and somehow manage to cope. Longer periods of abstinence always yielded what I guess other people would consider a normal life. I have won this battle and certainly lost the war... Abstinence these days is extremely easy, I can go on for months and months with complete Chasity, infact the longest I've gone is a year, this has destroyed me mentally... all in a vein attempt to allude POIS which has failed.

Not sure if this is a direct result of the above, but I have lost my libido completely... with the loss of libido has come with other consequences such as impotence, lethargy, loss of interest for all hobbies and I'm quite alienated from a lot of people in society, when out of POIS I can hold conversations for long, tell jokes, engage in sports and other recreational activities, but this is all accompanied with no feelings or passion, which is a very bad and unwanted feeling itself.

Regrettably the way I've dealt with it will probably have consequences till I die, but I'm forced to conceed to abstinence to survive as, simply the life I live and the things I do will not be attainable or sustainable if I engage in sexual activity, not even slightest, I'd soon find myself out of a home, food and the bare essentials to live.

I'm sure my coping strategies are not different from a lot of people on this site, infact I can't remember reading a single post on this site where a person reportedly engages sexual activity on a normal basis. I've tried and tested a lot of things and spent a colossal amount of money chasing after POIS. POIS is a lot more complex than what both studies report it to be.
« Last Edit: 18/08/2010 21:22:26 by green »
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Offline Green

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8888 on: 18/08/2010 21:24:16 »
Quote from: B_Jim on 18/08/2010 20:23:00
Don't use mega dose with Vitamin-D. Mega doses are used for rickets only.
1000 UI a day (during meal for better absorbtion, according to a study).

Many thanks for letting me know about that, I'll check it out and weigh up both sides of the argument before dosing on higer doses.
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Offline Vandemolen3

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8889 on: 18/08/2010 22:59:40 »
Quote from: green on 18/08/2010 20:17:23
Quote from: Vandemolen3 on 18/08/2010 15:30:54

No this all there was on the form.


VitD: I will call my familydoctor when the result is final.
Testosterone: 6-12 is normal/ on the lower side
A familydoctor will not intervene my himself when the TT is 11. Maybe I have to ask him myself for a test treatment. Or do you know if there 's a vitamin/ pills/ food diet you can buy to bring Testosterone up?


Diet, Stresses, Lifestyle, Sleep, Exercise, Nutrition all have a significant bearing on testosterone levels.

Living with POIS is a MEGA stressor, I struggle mentally quite a bit both in and out of POIS, so even if there is no direct link for testosterone reduction for POIS suffers, indirectly it must have some sort of significance.

Vitamin D3 has a significant impact on total testosterone [1]http://news.bbc.co.uk/1/hi/health/8493042.stm and overall wellbeing, but from my experience, this sentiment isn't shared by the doctors I've consulted in the past. I'm deficient in D3 and soon as I get some of these other blood tests out of the way I'm going to try my hand at mega doses of D3 (5000IU<d3<10000IU superficial doses (400IU what was recommended by my doctor) hasn't worked in my favour to increase my levels and on the surface, vitamin d toxicity is easily recognisable.

My argument for trying out mega doses is because one of my colleagues also has a deficiency her levels were slightly below mine and she qualifies for 50000IU injections, weekly till her levels fall into a suitable area in the range.

Converse with your doc to discuss options!

I am going to use for a month: Thyrax to raise my T4.
And I am going to use vitamin D pills from the drugstore.
And then I will go to the doctor and see if I made some progress. Maybe I need a mega dose of vitamin D too. I heard that there is a pill you have to take once a week. And this brings the vitamin D up. From some the vitamin D pills from the shop doesn't work enough.

Yes I know that sports help to raise testosterone. After a few weeks when I feel a bit better I am going too the gym again.
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Offline Vandemolen3

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8890 on: 18/08/2010 23:02:56 »
Quote from: B_Jim on 18/08/2010 20:23:00
Don't use mega dose with Vitamin-D. Mega doses are used for rickets only.
1000 UI a day (during meal for better absorbtion, according to a study).
I use only 2 pills a day. That's the maximum dose. I know that it's not good to use too much vitamin D.

The megadose vitamin D, once a week, is only by supervision of a doctor.
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Offline Vandemolen3

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8891 on: 18/08/2010 23:04:11 »
Quote from: demografx on 18/08/2010 21:04:07
Quote from: demografx on 11/08/2010 17:27:48

Hi everyone. Should I do this? Please let me know! (This is from
The Spoof Magazine
writer)

Hey, [demografx], I was thinking: Would you be willing to be the subject of a formal interview?  I would publish it in The Spoof Magazine, which is free form. I always conduct interviews via email, so there is never any question as to the accuracy of quotes. I would ask for a signed release, and offer you the right of final approval before publication. I own all my work published on thespoof.com, and would of course grant you license to do whatever you'd wish with it, including unlimited license to publish for profit. Let me know and we'll discuss in greater detail, OK? Thanks.


I've decided not to do the interview with The Spoof Magazine.

Many thanks, everyone, for your input, I really appreciated it!!

I think that's a wise decision.
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Offline Green

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8892 on: 18/08/2010 23:21:28 »
Quote from: Vandemolen3 on 18/08/2010 22:59:40

I am going to use for a month: Thyrax to raise my T4.
And I am going to use vitamin D pills from the drugstore.
And then I will go to the doctor and see if I made some progress. Maybe I need a mega dose of vitamin D too. I heard that there is a pill you have to take once a week. And this brings the vitamin D up. From some the vitamin D pills from the shop doesn't work enough.

Yes I know that sports help to raise testosterone. After a few weeks when I feel a bit better I am going too the gym again.

The conversion factor from nmol to ng/ml is 0.4 so your result will be 7.2ng/ml

Mine was 10.6ng/ml on a reference range of 11.1-42.9

Just remembered my mum is on monthly injections, her levels were ~6ng/ml

You might have a strong case to be put on injections by your GP if you wish.

Heavy squats are also a good way of increasing T levels :D
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Offline martin88

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8893 on: 19/08/2010 04:22:32 »
Even if I wasn't tested for vitamin D I think I can have it too low. I was improved (a lot more energy) with sun and with vitamin D from pharmacy (ddrops or sterogyl). Other brands I took were not very effective. I can't take more than 800UI/day or I feel restless, thirsty with headache.
The most effective was sterogyl, which is D2 not D3, even if people say D2 is not good.
Eventually vitamin D deficiency is a symptom of POIS and not a cause (link with endocrine gland parathyroid?)
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Offline GreenWyvern

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8894 on: 19/08/2010 09:23:48 »
Hi B_Jim,

Quote from: B_Jim on 18/08/2010 15:56:15

Hi Greenwyvern and welcome !
Thank you for L-carnitine.It's coincidence, I was just looking for it :) Do you suffer of flu-like symptoms during your very long Pois ? (fever or hot flash, joint pains, muscle aches...). What about exercice during Pois days ?


I do have some fever (body heated, but feeling cold as well), and muscle tension in my neck gets worse. There is physical weakness as well, and I get tired easily.

Quote from: B_Jim on 19/08/2010 06:48:19

Maybe I will test carnitine. Greenwyvern,
How much L-Cartinine do you take ? 500 mg a day ?
Does the positive effects come quickly or after some weeks ?


I'm taking one 500mg dose about mid-morning. It took about 2-3 weeks to have an effect, but then it was very noticeable. All the negative experiences were far less, and lasted far less time. A very big improvement. I'm still getting very good results, and continuing to improve.

For the first few days I was taking L-Carnitine I noticed that I sometimes felt angry, irritable, or hot after taking it, but this effect now seems to have disappeared.

Probably dosage and effects will vary from one person to another, but it may be worth trying. Good luck!
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Offline Vandemolen3

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8895 on: 19/08/2010 12:41:01 »
Quote from: green on 18/08/2010 23:21:28
Quote from: Vandemolen3 on 18/08/2010 22:59:40

I am going to use for a month: Thyrax to raise my T4.
And I am going to use vitamin D pills from the drugstore.
And then I will go to the doctor and see if I made some progress. Maybe I need a mega dose of vitamin D too. I heard that there is a pill you have to take once a week. And this brings the vitamin D up. From some the vitamin D pills from the shop doesn't work enough.

Yes I know that sports help to raise testosterone. After a few weeks when I feel a bit better I am going too the gym again.

The conversion factor from nmol to ng/ml is 0.4 so your result will be 7.2ng/ml

Mine was 10.6ng/ml on a reference range of 11.1-42.9

Just remembered my mum is on monthly injections, her levels were ~6ng/ml

You might have a strong case to be put on injections by your GP if you wish.

Heavy squats are also a good way of increasing T levels :D
Yes that's very low.
I will ask my doctor what is possble. I think he will say that I have to do another bloodtest and then decide what kind of Vitamin D-medicine I have to take.
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Offline Vandemolen3

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8896 on: 19/08/2010 12:42:42 »
Quote from: martin88 on 19/08/2010 04:22:32
Eventually vitamin D deficiency is a symptom of POIS and not a cause (link with endocrine gland parathyroid?)
I don't think so. My low Vitamin D is caused by a lack of sun. And I don't use milkproducts, sometime a little bit of cheese.
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Offline martin88

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8897 on: 19/08/2010 13:18:14 »
Quote from: B_Jim on 19/08/2010 06:48:19
yesterday it was my Day2, I do sport and after some kilometers I was really tired and concentration and mood start to decrease. I had a bad sleep too.
So, exercice has a big effect on my Pois and the best way to avoid symptoms is to be inactive and rest a lot.

Maybe I will test carnitine. Greenwyvern,
How much L-Cartinine do you take ? 500 mg a day ?
Does the positive effects come quickly or after some weeks ?

There are some positive articles on Carnitine :
http://cme.medscape.com/viewarticle/473414
Carnitine is more active than testosterone for improving symptoms of male aging such as sexual dysfunction, depressed mood, and fatigue, according to the results of a randomized study published in the April issue of Urology.
(2g a day ; 6 months :/ )

I'm also having severe problems with sport in POIS, with only 1-2 hours exercise each week since last November : increased difficulty to work in the following days, exhaustion, joint pain.
I just don't know what to do with that. I can stop but I think I need it for cardiovascular health so I don't (an other good reason for scientists to research about POIS!).
I must say that I have to stand up for a long time in my work and this doesn't help.

Thanks Greenwyvern for report. I tried l-carnitine 500mg for ten days after reading on androgen receptors (I think acetyl l carnitine was also mentionned by Michael a long time ago). I had no help from it. Maybe I'll try again with increased dosage.

Quote from: Vandemolen3 on 19/08/2010 12:42:42
Quote from: martin88 on 19/08/2010 04:22:32
Eventually vitamin D deficiency is a symptom of POIS and not a cause (link with endocrine gland parathyroid?)
I don't think so. My low Vitamin D is caused by a lack of sun. And I don't use milkproducts, sometime a little bit of cheese.
You're doing well, sun is not recommended by dermatologist associations, they suggest to take vit D supplement instead of sun. I think it depends how much exposure time. (I read on a naturopath site "half the time needed for the skin to turn pink is OK").
« Last Edit: 20/08/2010 10:28:10 by martin88 »
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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8898 on: 19/08/2010 18:04:51 »
Quote from: martin88 on 19/08/2010 04:22:32

Even if I wasn't tested for vitamin D I think I can have it too low.


I don't recall seeing it, how do we get tested for Vitamin D? Bloodtest with standard doctor's lab tests?
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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8899 on: 19/08/2010 18:07:40 »
Quote from: martin88 on 19/08/2010 13:18:14

...sun is not recommended by dermatologist associations,


Yes. As soon as I moved to this sunny clime, almost immediately after a few stays in the sun I developed a skin cancer on my nose (removed by dermatologist).
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