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  1. Naked Science Forum
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  4. Post Orgasmic Illness Syndrome (POIS)
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Post Orgasmic Illness Syndrome (POIS)

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Offline Vandemolen3

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8980 on: 25/08/2010 02:43:59 »
Quote from: GoingCrazy on 25/08/2010 02:29:06
Quote from: Vandemolen3 on 25/08/2010 02:25:16
Be carefull with nutmeg. An overdose nutmeg can be deadly!

For the people who believe the high cortisol theory:
Caffeine raises the cortisol level.

Ginseng and Relora brings cortisol down. Ginseng is Chinese.

The best way to lower the cortisol level is to stay relaxed, don't stress.

I am not going to try Relora or Ginseng before a urine test of my cortisol. Tommorow I will go to my specialist and ask for a test or he has to make an appointment about a week. He doesn't know why I have so many UTI's. Well I know, because of the high Cortisol.



Thanks for that vandemolen.  I was actually considering just taking the whole bottle 0_o

I support the cortisol theory too, as I thought my POIS began with the consumption of coffee.

I used to drink Ginseng A lot, but stopped, don't really know why I'm going to try drinking it again though.

Another reason I support the cortisol theory is because when I gamble, play highly competitive games, I can feel the POIS a lot more.  But, a reason that I doubt it is cortisol is because of my body weight, I am pretty thin, and I read that cortisol causes excess weight gain.
Don't forget that with every dissease some people don't get all the symptoms. And maybe some symptoms can come later.

I was really thin, but gained 20 kilo's. Now I am normal. But I have a little belly. I could control POIS a year ago. But then I had a lot of stress at work and a broken relationship. Then my POIS was very bad. I was very stressed. In the last months I slow it down.

I don't know if Ginseng helps. Try Relora. For others on this forum Relora worked very well. For me it's tempting to use Relora. But I don't want to lower my cortisol and then do a urine test. The doctor will say: you are OK. So first the test. And maybe the doctor will give me a real medicine and maybe a scan of my adrenal glands and the pituitary.
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Offline martin88

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8981 on: 25/08/2010 03:32:43 »
I'm not sure if this article was posted before: two interesting points among others:
"brain imaging"
what to look for if a scan is done in POIS.

and "The post-ejaculatory refractory period and ‘sexual satiety’"
7 ejaculations are necessary to cause complete satiation for 15 days (which I think is similar to POIS). Serotonin, opioids, dopamine, norepinephrine are all involved, NE being a key role in this mechanism.

http://joe.endocrinology-journals.org/cgi/content/full/186/3/411%20%20
« Last Edit: 25/08/2010 03:54:52 by martin88 »
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Offline Vandemolen3

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8982 on: 25/08/2010 04:00:40 »
High cortisol slows down the thyroid. My T4 was on the lower side. If cortisol is high for a long period the adrenal glands can be tired and stop working. Then you have another problem: low cortisol, which is dangerous. In that case you can have the Dissease of Adison.
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Offline John21 (OP)

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8983 on: 25/08/2010 10:18:24 »
Quote from: Vandemolen3 on 25/08/2010 02:25:16
Be carefull with nutmeg. An overdose nutmeg can be deadly!

For the people who believe the high cortisol theory:
Caffeine raises the cortisol level.

Ginseng and Relora brings cortisol down. Ginseng is Chinese.

The best way to lower the cortisol level is to stay relaxed, don't stress.

I am not going to try Relora or Ginseng before a urine test of my cortisol. Tommorow I will go to my specialist and ask for a test or he has to make an appointment about a week. He doesn't know why I have so many UTI's. Well I know, because of the high Cortisol.


Very good point, I should have noted that. Nutmeg is toxic in high doses, be careful!
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Offline Vandemolen3

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8984 on: 25/08/2010 12:39:03 »
Quote from: B_Jim on 25/08/2010 07:15:36
No, you don't have Addison because your cortisol is low. Your cortisol is low because you have Addison 's disease.

Nobody has Addison here. But we make the hypothesis cortisol (and other hormones) may be too high or too low for another cause.
Yes I know that now nobody has Addison. But in the long term it could. But let's forget the Addison theory.

There are two options for the cortisol:
1. Cushing. In most cases easy to find. A scan of the adrenal glands and the pituitary.
2. Another reason.

I'm off now to the urologist! Keep you posted.
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Offline Vandemolen3

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8985 on: 25/08/2010 15:18:51 »
The urologist said that for a cortisol test I had to contact the family doctor. The assistant of the family doctor gave me a form for cortisol. So about a week I will know my cortisol level.

It was strange that it was a bloodtest. I thought that cortisol was a urine test. They said the first time could be a bloodtest. When the cortisol level is not good then they check it trough urine.
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Offline Dave23

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8986 on: 25/08/2010 16:01:51 »
Blood cortisol tests can be inconsistent/inaccurate due to whitecoat syndrome giving false cortisol blood spikes.I and others have had normal to high blood cortisol but tested lower than bottom range on urine, saliva cortisol 4x aday..In my case saliva cortisol was always the lowest during in POIS mode.Cortef has helped alot with af and also pois.

I have addisons although I use the term adrenal fatigue and so does many on the Sexual exhaustion forum.
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Offline Vandemolen3

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8987 on: 25/08/2010 16:15:41 »
Quote from: Dave23 on 25/08/2010 16:01:51
Blood cortisol tests can be inconsistent/inaccurate due to whitecoat syndrome giving false cortisol blood spikes.I and others have had normal to high blood cortisol but tested lower than bottom range on urine, saliva cortisol 4x aday..In my case saliva cortisol was always the lowest during in POIS mode.Cortef has helped alot with af and also pois.

I have addisons although I use the term adrenal fatigue and so does many on the Sexual exhaustion forum.
Thanks for the information Dave. I think a blood tes is the first step. When they see something I will ask my familydoctor to send me to the endo. And then the endo will ask for a urine test for cortisol.

So you have Addison/ adrenal fatigue. Sorry to hear that. But it's interresting that you mention it. I saw on B_Jims list that you use Relora. Isn't that strange because Relora brings cortisol down. And you have already a low cortisol level because of Addison.

I thought that all POIS-sufferers will have a high cortisol. If there is something with my adrenal glands it would be Cushing. If someone has Cushing there is a cyste on the adrenal gland or the pituitary. But there can be a cyste on another place which raises the cortisol level. I have got a cyste betweem the anus and the scrotum. Since I discovered the cyste, more than 5 years ago, I have POIS-symptoms.

Last week I thought that if someone is cured/handled for Cushing or Addison this person would also be cured for POIS.

P.S. For me the test is done in day 3 in POIS mode.
« Last Edit: 25/08/2010 18:05:30 by Vandemolen3 »
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Offline girlwind

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8988 on: 25/08/2010 17:45:32 »
Hi Everybody--

I just received a note from Cconfucius about the upcoming Waldinger research papers. This is exciting news.

As some of you may remember, my primary health issue is Chronic Fatigue Syndrome (CFS), and POIS is secondary to that. Recently CFS has been in the news again as well, due to breakthroughs in research on that front.

Last October (2009), researchers at the Whittemore Peterson Institute (in conjunction with Cleveland Clinic and the National Cancer Institute) discovered the XMRV retrovirus (Xenotropic Murine Leukemia Virus Related Virus) in 67 of 101 blood samples of CFS patients they studied. XMRV was also found in about 4% of healthy controls. The findings (by Lombardi, Ruscetti,  Mikovits, et al) came out in the prestigious journal of Science.  http://www.sciencemag.org/cgi/content/abstract/1179052

Just two days ago the PNAS (FINALLY!) published a new research paper by Alter and Lo that has pretty much replicated the XMRV findings! http://www.nytimes.com/2010/08/24/health/research/24fatigue.html?_r=2

Judy Mikovits of WPI explains the Alter and Lo findings here.

News had leaked back in June about Harvey Alter's (of NIH) and Shyh Ching Lo's (of FDA) work, but their paper was delayed by the usual CDC political shenanigans. It turns out that the CDC had conducted its own XMRV study (using the wrong cohort and questionable procedures) and had gotten negative XMRV findings, so (as usual) they interfered and did their damnedest to delay publishing of the Alter/Lo PNAS paper. I can't tell you how thrilled everyone is now that the paper is published. It will bring more attention, research and treatment possibilities to those who suffer from CFS.

Anyone who has CFS as well as POIS will be able to find additional info if they just google.

I look forward to more info about the upcoming Waldinger research on POIS.
All the best to you,  GW



 
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Offline Vandemolen3

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8989 on: 25/08/2010 18:09:49 »
There is also a Belgian research for CFS, just published today in the Belgian newspapers:

http://translate.google.nl/translate?u=http%3A%2F%2Fwww.nieuwsblad.be%2Farticle%2Fdetail.aspx%3Farticleid%3DGGM2UERL7&sl=nl&tl=en&hl=&ie=UTF-8
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Offline Dave23

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8990 on: 25/08/2010 18:11:41 »
Quote from: Vandemolen3 on 25/08/2010 16:15:41
Quote from: Dave23 on 25/08/2010 16:01:51
Blood cortisol tests can be inconsistent/inaccurate due to whitecoat syndrome giving false cortisol blood spikes.I and others have had normal to high blood cortisol but tested lower than bottom range on urine, saliva cortisol 4x aday..In my case saliva cortisol was always the lowest during in POIS mode.Cortef has helped alot with af and also pois.

I have addisons although I use the term adrenal fatigue and so does many on the Sexual exhaustion forum.
Thanks for the information Dave. I think a blood tes is the first step. When they see something I will ask my familydoctor to send me to the endo. And then the endo will ask for a urine test for cortisol.

So you have Addison/ adrenal fatigue. Sorry to hear that. But it's interresting that you mention it. I thought that all POIS-sufferers will have a high cortisol. If there is something with my adrenal glands it would be Cushing. If someone has Cushing there is a cyste on the adrenal gland or the pituitary. But there can be a cyste on another place which raises the cortisol level. I have got a cyste betweem the anus and the scrotum. Since I discovered the cyste, more than 5 years ago, I have POIS-symptoms.

P.S. For me the test is done in day 3 in POIS mode.

Your welcome Van, dont be sorry Ive been pois free for quite a while now by optimising my hormone profile with help from couple of docs.

You said :

When* they see something I will ask my familydoctor to send me to the endo.And then the endo will ask for a urine test for cortisol.

Thats could be the problem that gets away down the road ..  9/10 your blood cortisol will likely be normal, within range but like i said due to whitecoat syndrome unless you have extremely low cortisol levels that even the white coat syndrome doesnt
bring it high enough to be in the *normal range. Make sure to have your endo test you for urine/saliva cortisol even if blood is in range especially if one feels they have adrenal fatigue type symptoms which can be identical to POIS symptoms depending on the Pois individual  .. *for the benefit of your health and others.

So you have cyste on your prostate muscle, do you experience any unusual or changes in prostate contractions during the point of ejaculation since having this cyste on prostate?

I had a cyste that wouldnt stop growing, hanging of my earlobe many moons ago , luckily it
was external and got it removed without being comatosed. However during this period or not long after I started experiencing adrenal fatigue symptoms and not long after POIS symptoms. Now i remember the doc i spoke to before having the cyste removed said its a sign of high stress which brings on high cortisol. First signs of adrenal fatigue is high stress/high cortisol due to burn out either from mental, physical, emotional stress of combination of above ...
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Offline Vandemolen3

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8991 on: 25/08/2010 18:38:47 »
Quote from: Dave23 on 25/08/2010 18:11:41
Your welcome Van, dont be sorry Ive been pois free for quite a while now by optimising my hormone profile with help from couple of docs.

You said :

When* they see something I will ask my familydoctor to send me to the endo.And then the endo will ask for a urine test for cortisol.

Thats could be the problem that gets away down the road ..  9/10 your blood cortisol will likely be normal, within range but like i said due to whitecoat syndrome unless you have extremely low cortisol levels that even the white coat syndrome doesnt
bring it high enough to be in the *normal range. Make sure to have your endo test you for urine/saliva cortisol even if blood is in range especially if one feels they have adrenal fatigue type symptoms which can be identical to POIS symptoms depending on the Pois individual  .. *for the benefit of your health and others.

So you have cyste on your prostate muscle, do you experience any unusual or changes in prostate contractions during the point of ejaculation since having this cyste on prostate?

I had a cyste that wouldnt stop growing, hanging of my earlobe many moons ago , luckily it
was external and got it removed without being comatosed. However during this period or not long after I started experiencing adrenal fatigue symptoms and not long after POIS symptoms. Now i remember the doc i spoke to before having the cyste removed said its a sign of high stress which brings on high cortisol. First signs of adrenal fatigue is high stress/high cortisol due to burn out either from mental, physical, emotional stress of combination of above ...
The cyste and POIS came six years ago. I don't know if there is a connection. A few weeks ago I had a scan in the prostate. There was nothing to see. This research was done by a replacer because my urologist was called for an emergency case. One appointment before I mentioned the cyste to my urologist. I said that maybe the cyste oppress the prostate. He said that it's possible and that we have to wait the scan. But his replacer didn't mention it. And I was forgotten it because I was happy that it wasn't cancer in the prostate.
But the only unusual thing about the cyste/prostate is that I couldn't have a full O since I discovered the cyste. That was the reason to go to urologist. He said that it was just a UTI.
But in stress the cyste grows. It's more internal.

About a few weeks I already have an appointment with my familydoctor to discuss the resultst of the last blood test (low Vitamin D) and my experiment with Thyrax. So if the cortisol test is not out of range, I will ask him to send me to the endo.

P.S.  I saw on B_Jims list that you use Relora. Isn't that strange because Relora brings cortisol down. And you have already a low cortisol level because of Addison.
« Last Edit: 25/08/2010 18:42:25 by Vandemolen3 »
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Offline Dave23

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8992 on: 25/08/2010 18:40:59 »
Quote from: Vandemolen3 on 21/08/2010 23:31:29
There are 2 major disorders of adrenal glands: Dissease of Adison and Cushing's syndrome. I don't think POIS-patiensts have Cushing because you have to see this on your side:



See my earlier post about adrenal glands.
Quote from: Vandemolen3 on 09/08/2010 22:08:55
Stress might be a factor. The famous Britisch writer Jane Austen died because of the dissaese of Adison. That's a dissease when the drenal cortex doesn't produce enough cortisol and aldosterone. She died in the 19th century, so no worries. Nowadays that can't cure Adison, but they have a treatment. Adison is rare, 120 per million people.
During a stressful situation into the adrenal glands normally cortisol, which enables the body to deal with that situation. In people with Addison's disease can be very serious stressful situations lead to a crisis of Addison and a shock.

With POIS you don't get a shock. But an O might be a stressfull situation for the body. So I am in for the cortisol theory. Does someone know which vitamins/pills you can use for a shortage of cortisol? Something you can buy without perscription. We all have too experiment a bit. Offcourse we have to be carefull. I ordered Fenugreek and Mecuna Pruriens.

P.S. Or is the opposite with POIS: drenal cortex  makes too much cortisol after an O?
Interesting post but mostly picture stood out since i have these marks on shoulders, chest, hips, legs all over actually.
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Offline CertainlyPOIS

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8993 on: 25/08/2010 18:52:11 »
Bjim in addition to trying l-cartinine, you should look into vinpocetine, is a nootropic that boost brain flow, help with concentration, memory cognitiion, glucose metabolism, and to be great antioxidant.   
I loooked at some acientific article on it, and they concluded it works and safe to use by itself and with other medicines, i am thinking of trying vinpocetine with l-cartinine. 
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Offline Dave23

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8994 on: 25/08/2010 19:12:52 »
Quote from: B_Jim on 25/08/2010 18:26:42
Quote from: Vandemolen3 on 25/08/2010 12:39:03

 But in the long term it could. But let's forget the Addison theory.


No, you can't.
We must be careful the words we use here.

Addison's disease : destruction of adrenal glands and need to take cortisol to stay alive.

adrenal insufficiency : the low levels are proved by cortisol test (urine or blood test. Controversy for saliva test). But the cause is not inevitably Addison.

Adrenal fatigue : it's a supposed adrenal insufficiency which is not really proved by biological test. Anyway the Who seems to consider it as a real disorder since 2010.

Dave, i supose you have adrenal insufficiency and not Addison. I'm reading your last posts and I have a lot of questions :)



Hi Jim,

Doc diagnosed me with adrenal fatigue and possibly addisons from very low cortisol levels
from morning, noon, afternoon to evening and *slightly low aldosterone, extremely low sodium levels as well. Some slight differences between both illnesses...

Also had very low urine 24hr cortisol
levels as well as the cortisol metabolites.

I cant get by a day without cortef(cortisol/hydrocortisone med)
will be stuck sick in bed. It makes sense since cortisol is the only hormone a human being cannot physically live without.

My dosing is 10mg morning, 5mg 3hrs later and 5mg 3hrs after. If i miss
a dose adrenal fatigue symptoms will kick in. Before each sex session i will
do a 5-10mg cortef dose since I know cortisol will rise
initially after orgasm from saliva cortisol test but then will drop extremely low
the morning after sex. The morning after each sex session i need a higher cortef
dose to replace the extremely low level of cortisol from 10mg to 20mg along with celtic sea salt 1teaspoon in glass of warm water.

The study you posted is interesting since watching porn increases testosterone,
lowers prolactin, increases dopamine which would influence one strongly
to have sex to have an orgasm but the side effect from the study is lowered
cortisol which low cortisol is linked to adrenal fatigue/addisons which the symptoms
can be similar to POIS.

Bring on the questions Jim! ;)
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Offline Dave23

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8995 on: 25/08/2010 19:30:33 »
Quote from: Vandemolen3 on 25/08/2010 18:38:47

The cyste and POIS came six years ago. I don't know if there is a connection. A few weeks ago I had a scan in the prostate. There was nothing to see. This research was done by a replacer because my urologist was called for an emergency case. One appointment before I mentioned the cyste to my urologist. I said that maybe the cyste oppress the prostate. He said that it's possible and that we have to wait the scan. But his replacer didn't mention it. And I was forgotten it because I was happy that it wasn't cancer in the prostate.
But the only unusual thing about the cyste/prostate is that I couldn't have a full O since I discovered the cyste. That was the reason to go to urologist. He said that it was just a UTI.
But in stress the cyste grows. It's more internal.

About a few weeks I already have an appointment with my familydoctor to discuss the resultst of the last blood test (low Vitamin D) and my experiment with Thyrax. So if the cortisol test is not out of range, I will ask him to send me to the endo.

P.S.  I saw on B_Jims list that you use Relora. Isn't that strange because Relora brings cortisol down. And you have already a low cortisol level because of Addison.

Maybe the cyste is blocking the actual ejaculation process in the prostate thus not able to have an orgasm unlike before having the cyste .. i had low vitamin d3 blood results as well .. got it up to 80 with 10000iu of VIt D3 liquid emulsion.
Body wouldnt absorb vit d3 capsules/gels etc

Low vit D comes with the pois territory, from the symptoms I stayed in 99.99% of the time all year no sun so less vit d3 and also less thyroid hormones which Im on armour for hypothyroidism as well.

hehe that was a few years ago in regards to the relora, i first posted on this thread on page 4 dispite my low newbie post count ;)
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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8996 on: 25/08/2010 19:38:22 »

A different POIS spoof:


http://itsonlyfashionblog.com/2010/08/24/and-now-ive-got-post-orgasmic-illness-syndrome/
« Last Edit: 26/08/2010 03:29:36 by demografx »
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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8997 on: 25/08/2010 19:50:02 »

Hi, Girlwind, sorry I didn't mention that in my last PM to you!
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Offline Vandemolen3

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8998 on: 25/08/2010 19:57:35 »
Quote from: Dave23 on 25/08/2010 19:30:33
Maybe the cyste is blocking the actual ejaculation process in the prostate thus not able to have an orgasm unlike before having the cyste .. i had low vitamin d3 blood results as well .. got it up to 80 with 10000iu of VIt D3 liquid emulsion.
Body wouldnt absorb vit d3 capsules/gels etc

Low vit D comes with the pois territory, from the symptoms I stayed in 99.99% of the time all year no sun so less vit d3 and also less thyroid hormones which Im on armour for hypothyroidism as well.

hehe that was a few years ago in regards to the relora, i first posted on this thread on page 4 dispite my low newbie post count ;)
That's possible.

But did you had a scan of your adrenal glands and the pituitary?

Relora: ah, that's why. :)
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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #8999 on: 25/08/2010 20:03:51 »

My pituitary scan revealed nothing.
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