Cardiac Pathology: Congenital: Transposition of the great vessels: Pulmonary artery aneurysm
A 1966 autopsy specimen from a man who was 27 when he died. He had been cyanosed from birth and suffered marked exertional dyspnoea. There were several attacks of fever and pain (suggestive of bacterial endocarditis) but blood cultures were always sterile. In his later years, he developed large collections of uric acid around the joints of fingers and toes, and gouty tophi of the ears, complications of the secondary polycythaemia which accompanied his heart defects.