Gastrointestinal Pathology: Large Intestine: Hirschsprung's Disease of the Rectum

01 April 2011
Presented by Simon Cross


A 1972 autopsy specimen from a 4 month old boy, constipated since birth, who did not pass meconium until a rectal examination performed on the fourth day. Abdominal x-ray confirmed colonic dilatation with absence of gas in the rectum on inversion. A barium enema confirmed constriction at the recto-sigmoid junction with proximal dilatation. Hirschsprung's disease was diagnosed. The infant died of pseudomonas meningitis before a right transverse colostomy could be performed.


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