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Remodelling accelerated ageing
... Syndrome (HGPS), a rare but distressing accelerated ageing disease. Caused by an unknown genetic fault, people ... NAT10, which was not previously known to be involved in ageing, and seems to work in a different way from existing ... way for treatments for other diseases that also involve ageing processes, including cancer, and even ways of tackling ...
Cambridge Cafe Scientifique Vodcast - Dementia and an Ageing Population
Professor Carol Brayne discusses the consequences of our ageing population and looks into the symptoms, diagnosis and prevention of dementia and other diseases related to ageing. Professor Carol Brayne discusses the consequences of our ageing population and looks into the symptoms, diagnosis and ...
Worms may hold the secret to longer life
... researchers have a secret weapon in the battle with the ageing process – the humble worm. Flatworms have the ... creatures as a rich source of potential clues about the ageing process and how we too might regenerate tissues. In a ... in the tidal sands of the Adriatic Sea, to investigate ageing mechanisms. Previous research observed that the ...
Why do we grow old?
Ageing happens to each and every one of us, but what is ... Judy - Of course, we don’t have a clear definition of ageing except to say that it’s a process by which multiple ... parts of the body? Judy - It’s interesting that ageing affects different tissues in different ways, but also ...
Microbes Extend Healthy Lifespan
Chemicals released by gut microbes slow down the ageing process in worms, flies and even mice, scientists ... in gene expression that are normally associated with ageing, producing a gene profile in an elderly worm much more ... to simply extending how long we live." indoles_flies_ageing.gif Credit: Daniel Kalman, Emory University ...
Brain activity staves off dementia
... to get meaningful results. The Irish longitudinal study on ageing has been following over 8000 people over the age of ... Robertson is interested in how society’s stereotypes of ageing can impact people’s experience of ageing and how this can lead to, or prevent dementia. ...
Crash test dummies based on older bodies could reduce road fatalities
Europe’s population is ageing rapidly, yet the majority of car safety equipment is ... by 2021. By Catherine Collins Europe’s population is ageing rapidly, yet the majority of car safety equipment is ...
Anti-ageing treatment… for mice
... wanting to turn back the clock and erase the signs of ageing. Researchers at Erasmus University Medical Center in ... to arrive. The scientists saw fur growing back in balding, ageing mice after just 10 days of treatment, with fitness ... So it’s still likely to be some time before an anti-ageing drug becomes a reality. Researchers find a molecule ...
Restoring the Masters
... paintings here in the museum that show overall patterns of ageing cracks and then specific areas of drying cracks, and ... Ginny - What's the difference between drying cracks and ageing cracks? Sally - Superficially, you can see a ... which occurred at much earlier stage in the painting's ageing when the painting is drying and is still a quite ...
Modelling Alzheimer's Disease
... the healthy participants to study the process of healthy ageing while we use the Alzheimer's patients to study ... disease is a much more complex process than healthy ageing. So, for example, the number of genes that we found to underline healthy ageing were just eight, while the number of genes that we ...
Intervention doubles worm lifespan, even given in old age
... death and taxes." But before the death bit usually comes ageing first, and that's something of a scientific mystery: ... As he explained to Chris Smith, would worms in which an ageing-linked gene is deactivated later in life still ... called C.elegans. It's a great model organism for ageing research because it lives for three weeks. Just a ...
The great fly gender divide
... extended. Chris - If one studies the natural history of ageing in these flies (males versus females) and you look ... we did in parallel. We started to look at the guts of ageing males and ageing females and when we started out we expected that we ...
Can gut bugs keep you healthy for longer?
... factor from the bacteria and the worms show accelerated ageing, or their more frail, that molecule coming from those bugs might be involved in the ageing process? Daniel - Correct. Though the molecules that ... a lot of the things that we associate with health versus ageing. Chris - What are those molecules? Daniel - The ...
Gene signal informs Alzheimer's risk
... a profile covering 150 genes that can be used as a healthy ageing benchmark dubbed a "healthy ageing gene score" by the team. In the group of subjects ... examined, there was a 400 percent range in the healthy ageing gene score. "If we look at people aged 40 and 50, we ...
Parasites and the ageing process
“We’re ageing faster and afflicted by allergies and inflammatory ... bodies, could actually protect against certain diseases of ageing. Chris - Because, for a long time, people have ... of worms and possibly other parasites to control the ageing process or control their disease. They probably feel a ...
Gender divide: why females outlive males
... extended. Chris - If one studies the natural history of ageing in these flies – males versus females and you look ... we did. In parallel, we started to look at the guts of ageing males and ageing females. When we started out, we expected that we ...
Michael Shannack - Fat, old flies
... to our age-old topic, at the UCL Institute of Healthy Ageing. Student Michael Shannack has been studying fruit ... in and this is something that's kind of common in ageing research is to try and stress test the things that ... was Michael Shannack, from the UCL Institute of Healthy Ageing. Michael Shannack, UCL Institute of Healthy Ageing ...
Nazif Alic - Manipulating metabolism
... topic, with Dr Nazif Alic at the UCL Institute of Healthy Ageing. He's figuring out if tweaking some of the genes ... you actually look at these flies and work out how they're ageing? Nazif - So, one of the main outputs that we've been ... - That was Nazif Alic from the UCL Institute of Healthy Ageing. Nazif Alic, UCL Institute for Healthy Ageing Tweaking ...
Can cycling keep you younger?
... life has big health benefits. But can it slow down the ageing process? One problem with studying this is that most ... to know whether some of the health issues seen in ageing, such as heart and lung problems or loss of muscle and ... Staying active into older age appears to stave off the ageing process, new research shows Can cycling keep you ...
Sleep cell loss explains poor repose
... and are lost from the brain through the effects of ageing and disease lead to disturbed sleep in old age, ... in a community-based study called the "Rush Memory and Ageing Project". These participants had been followed since ... "sleep-switch", lost from the brain through the effects of ageing and disease, leads to disturbed sleep in old age... ...
How head trauma leads to dementia
... looked at what their brains looked like compared to normal ageing brains. And what we found in that was that they had a ... in patients who’d had a brain injury than in normal ageing. Chris - So when you say it’s in a wider ... was that tau protein was throughout their brain. In normal ageing it can just be in tiny spots here and there as part of ...
Does gravity affect how the body ages?
... of white blood cells). So actually there is an advanced ageing effect owing to radiation exposure which outpaces the ... to a massive gravity your time does slow down but does the ageing slow as well? And if yes, how? Let me rephrase my ... possible that MR. Smith's body has slowed it's "natural" ageing process while on this trip? Do we have some internal ...
The science of skincare
... Chris - And why is that? Jane - That’s a natural ageing process but that’s magnified by the effects of the ... to a supermarket or chemist or something and buy and anti-ageing cream or something to make me look a bit younger, how ... can lose that. But the creams that are put forward as anti-ageing creams, there’s a bit of a debate as to how well ...
Do Zombie cells promote arterial disease?
It’s a fact of life that we’re all ageing, all the time. And as we age, an increasing proportion ... explain how this relates to a concept of a whole person ageing? Martin - As we age, a greater proportion of our cells ... functioning of many many organs associated just with ageing. Professor Martin Bennett - Cambridge University As we ...
Reversing ageing in the brain
... good working order. The good news is that this aspect of ageing it might be reversible. To explain how, Robin Franklin ... duration there's a big problem of how you deal with the ageing phenomenon in the adult stem cell. Chris - And Kevin ... research reveals the same is true for our brain. Reversing ageing in the brain ...