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Old woman

Prof David Gems - Healthy ageing

... disease. Cheery stuff. At the UCL Institute of Healthy ageing, researchers are investigating the genetics of ageing, and how understanding the fundamental biological ... biogerontology, and started by asking him what we mean by "ageing". David -   The word 'ageing' is a very slippery term ...

A happy, healthy older man

Ageing and Bioscience at the Babraham Institute

... were brought together recently for conference on Ageing and Bioscience, hosted by the Babraham Institute just ... Partridge and I'm Director of the Institute of Healthy Ageing at UCL.  A very practical problem, I think, is the ... healthy as they get older.  The economic impact of the ageing population on health services is just becoming ...

Does your DNA impact your lifespan?

Do we know which parts of our DNA relate to our ageing, and how much of an effect it has? Georgia Mills spoke ... than for the rest of us. Joao - I became interested in ageing when I was a child. I was quite young and I first ... the internet so I wasn’t even aware that you could study ageing, but I was aware of the biomedical research. I knew we ...

Ageing effect on worm reproduction

... gene, or a gene, which might be linked to this premature ageing phenomenon that you were searching for? L. Rene -   ... regulates the durability of the circuit as the animal is ageing. Chris -   What does Sir-2 do?  How does it work?  And how does it influence this ageing process? L. Rene -   Sir-2 is an enzyme that ...

Why Senior Moments Are Not Inevitable

... span. It's quite well-known that even with normal healthy ageing, we do seem to see a decline in our cognitive ... memory, attention, etc. - and the Cambridge's Centre for Ageing and Neuroscience or Cam-CAN was setup to try and ... is affected very strongly indeed by our stereotypes of ageing. Ben -   So, if we expect that we are getting ...

Insulin crystals

Jennifer Tullett - Ageing & metabolism

... a look at the researchers hunting for the genes behind ageing, and now we're returning to the topic with a closer look at the links between genes, ageing and metabolism - that's how we use food to generate ... at different transcription factors that are involved in ageing.  Transcription factors are proteins that are ...

The process of synaptic transmission in neurones.

Teaching old dogs new tricks

... is that drawing any firm conclusions about the effects of ageing on our cognition is very difficult. Despite this, ... to better understand the consequences of the normal ageing process for cognition, focusing in particular on ... So, what do we know about the consequences of the normal ageing process for learning? At a biological level, when it ...

Harvesting bone marrow

Would self bone marrow transplants reverse aging?

... Professor Tom Kirkwood at Newcastle University... Tom - Ageing is complicated. We know that the underlying reason ... membranes that make up the cells. So basically, the ageing process is driven by things going wrong, cells become ... the body do themselves experience some form of intrinsic ageing. So, in theory, one might think that a good way to ...

The effects of old age on the human face. Portrait of Elisabetha Drum of Kittsee, Austria. Created by Michael Ströck

How old are you really?

... The team, from Duke University, also measured the 'pace of ageing' in the study group. This was calculated using the ... of those lines to produce an estimate for the pace of ageing. Most participants were found to be ageing at the expected rate of around 1 biological year per ...

Old lady from Zacatecas, Mexico

Younger Looking Skin

Meera - Whilst ageing is both a physical and psychological process, when ... companies promise, it's possible to reverse the effects of ageing... Patrick - The skin is the largest organ in our ... purely targeting people that are wanting to reverse their ageing? Patrick - We had about 25 years ago a big ...

Old lady from Zacatecas, Mexico

Younger-looking Skin

Meera - Whilst ageing is both a physical and psychological process, when ... companies promise, it's possible to reverse the effects of ageing. Patrick - The skin is the largest organ in our body. ... purely targeting people that are wanting to reverse their ageing? Patrick - We had about 25 years ago a big ...

GFP-expressing nerve cells in the mouse cerebral cortex

Protecting Neurons from Age-Related Decline

... developments on your work, today, we're talking about ageing.  What does this nerve degeneration process have to do with ageing? Michael -   So, in answer to one of your earlier ... and in certain types of neurodegenerative disease.  And ageing if you like, is a big new growth area in biomedical ...

Animation of the structure of a section of DNA. The bases lie horizontally between the two spiraling strands.

Damaged DNA

... such as cancer and we believe it can also contribute to ageing. Helen - You touched on the idea that we might be able ... a bet that it would slow down at least some aspects of ageing, maybe not all of them. The problem is that our cells ... of bringing that about then that might actually slow down ageing at a cellular level. Helen - So if we could tease ...

The naked mole-rat’s genes could inspire ways to delay the ageing process and treat strokes in humans.

Uncovering the secrets of the naked mole-rat

... its genes that could provide cures for strokes, delay the ageing process, and even increase our lifespan. These tiny, ... entire genome. It initially focused on genes relating to ageing, a key interest for researcher Dr João Pedro de ... at the University of Liverpool, UK. He wants to delay the ageing process, and turn back the clock to put a spring in ...

What Determines Female Fertility?

... quality. What people may not realise is that reproductive ageing in females begins when they reach their mid 30s, and ... menopause around age 50. So really, female reproductive ageing is one of the first organ systems in the human body to show signs of overt ageing. Georgia - Do we know why this is? Francesca - My ...

The effects of old age on the human face. Portrait of Elisabetha Drum of Kittsee, Austria. Created by Michael Ströck

Cambridge Cafe Scientifique - Dementia and an Ageing Population

... Professor Carol Brayne discusses the consequences of our ageing population and looks into the symptoms, diagnosis and prevention of dementia and other diseases related to ageing. We also hear how ageing can be studies using populations and find out audience ...

Clock

Could humans live forever?

Some animals appear to be able to reject the processes of ageing completely. Could this ever be the case in humans? ... based in California, which aims to reduce the damage of ageing and allow people to live younger. Aubrey - The body ... of the way the body normally works and, in that sense, ageing in a living organism like you or me is exactly the ...

Anti-senescence drug reverses ageing in old mice

Drug reverses ageing in mice

A drug that reverses the ageing process and makes balding mice hairy again, restores ... and other factors that actually accelerate the ageing process. Removing them is known to lead to ... before also injecting it into mice with an accelerated ageing syndrome as well as naturally aged animals. In the ...

Elderly man holding a watch

British Science Festival 2013: Healthy Life Simulation

The population of the modern world is ageing. However, not everyone's quality of ageing is equal and simple factors, such as where we live, ... are in to old age. Peter Gore, Professor of Practice for Ageing and Vitality at Newcastle University is part of a ...

Mouse on the left recieved the treatment compared to mouse who didn't.

Anti-ageing protein reverses senescence

A drug that reverses the ageing process has been unveiled by scientists in the ... of these senescent cells which are contributing to the ageing process and therefore you could, at the very worst, potentially arrest ageing and maybe even wind the clock back a bit? Peter - ...

Telomere caps

Healthy living reverses ageing

... and stress management, reversed genetic markers of human ageing, a new study has shown. Thirty five older men were ... times a cell can divide. As such, they provide an index of ageing and are a prognostic marker for risk of succumbing to ... to be slowing and even reversing the biochemical signs of ageing. Moreover, the better that subjects adhered to the ...

Chromosome territories in the nucleus

Remodelling accelerated ageing

... Syndrome (HGPS), a rare but distressing accelerated ageing disease.  Caused by an unknown genetic fault, people ... NAT10, which was not previously known to be involved in ageing, and seems to work in a different way from existing ... way for treatments for other diseases that also involve ageing processes, including cancer, and even ways of tackling ...

Cambridge Cafe Scientifique Vodcast - Dementia and an Ageing Population

Professor Carol Brayne discusses the consequences of our ageing population and looks into the symptoms, diagnosis and prevention of dementia and other diseases related to ageing. Professor Carol Brayne discusses the consequences of our ageing population and looks into the symptoms, diagnosis and ...

The regenerative abilities of the flatworm Macrostomum lignano serve as a model for how humans might regenerate tissues.

Worms may hold the secret to longer life

... researchers have a secret weapon in the battle with the ageing process – the humble worm. Flatworms have the ... creatures as a rich source of potential clues about the ageing process and how we too might regenerate tissues. In a ... in the tidal sands of the Adriatic Sea, to investigate ageing mechanisms. Previous research observed that the ...

Tree rings

Why do we grow old?

Ageing happens to each and every one of us, but what is ... Judy - Of course, we don’t have a clear definition of ageing except to say that it’s a process by which multiple ... parts of the body? Judy - It’s interesting that ageing affects different tissues in different ways, but also ...